ID A0A086JNU3_TOXGO Unreviewed; 609 AA. AC A0A086JNU3; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 09-DEC-2015, entry version 7. DE SubName: Full=3'5'-cyclic nucleotide phosphodiesterase domain-containing protein {ECO:0000313|EMBL:KFG33811.1}; DE EC=3.1.4.17 {ECO:0000313|EMBL:KFG33811.1}; GN ORFNames=TGDOM2_258508 {ECO:0000313|EMBL:KFG33811.1}; OS Toxoplasma gondii GAB2-2007-GAL-DOM2. OC Eukaryota; Alveolata; Apicomplexa; Conoidasida; Coccidia; OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma. OX NCBI_TaxID=1130820 {ECO:0000313|EMBL:KFG33811.1, ECO:0000313|Proteomes:UP000028837}; RN [1] {ECO:0000313|EMBL:KFG33811.1, ECO:0000313|Proteomes:UP000028837} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=GAB2-2007-GAL-DOM2 {ECO:0000313|EMBL:KFG33811.1, RC ECO:0000313|Proteomes:UP000028837}; RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., RA Brunk B., Roos D., Caler E., Lorenzi H.; RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:KFG33811.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AHZU02001301; KFG33811.1; -; Genomic_DNA. DR EnsemblProtists; KFG33811; KFG33811; TGDOM2_258508. DR Proteomes; UP000028837; Unassembled WGS sequence. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:UniProtKB-EC. DR GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR Gene3D; 1.10.1300.10; -; 1. DR Gene3D; 1.20.120.350; -; 1. DR InterPro; IPR027359; Channel_four-helix_dom. DR InterPro; IPR005821; Ion_trans_dom. DR InterPro; IPR002073; PDEase_catalytic_dom. DR Pfam; PF00520; Ion_trans; 1. DR Pfam; PF00233; PDEase_I; 1. PE 4: Predicted; KW Complete proteome {ECO:0000313|Proteomes:UP000028837}; KW Hydrolase {ECO:0000313|EMBL:KFG33811.1}; KW Ion channel {ECO:0000256|RuleBase:RU003378, KW ECO:0000256|SAAS:SAAS00005980}; KW Ion transport {ECO:0000256|RuleBase:RU003378, KW ECO:0000256|SAAS:SAAS00005966}; KW Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius}; KW Transmembrane {ECO:0000256|RuleBase:RU003378, KW ECO:0000256|SAAS:SAAS00084820, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00084701, KW ECO:0000256|SAM:Phobius}; KW Transport {ECO:0000256|RuleBase:RU003378, KW ECO:0000256|SAAS:SAAS00005856}; KW Voltage-gated channel {ECO:0000256|SAAS:SAAS00005871}. FT TRANSMEM 48 73 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 10 85 Ion_trans. {ECO:0000259|Pfam:PF00520}. FT DOMAIN 361 587 PDEase_I. {ECO:0000259|Pfam:PF00233}. SQ SEQUENCE 609 AA; 68371 MW; 446ACC29FD6E172B CRC64; MHISCVKGRI VARQIDNVFT VIFAIEVLGK FVSYGLEYLQ DPIESFDTIV VLTSFTLLVL GFYVSGIGLL RILRLLSALA LLHKYPDSKE KRPELSAGNS SKLEKASSIV EGLLTNVHIP KYFKTELEWV WDSILANKVY DSHVVENEEE EEDQATETII AGSDASRKTQ AAVRASRAQS RASKLPHGSS SMVVGTTNGR ISGQILETLR EPDPRMMDAA LYKSETRNLD PLTATVGGMK NSPSMFAKGS KSSNMMGSSA SKSFRTERNK KAIDIISVLY QASQITGAEQ EQVNEAMRPF DEWQWDALHA GDVCDMNLLP VVFVRAIATF PTIMTKFNFD LDRLFDFLKV VQTSFQKNVK FHCAAHTADM IQAMHYFLTI GKLGALLSEY DVFLCHFCAL VCHFGHPGVT NTFLVKSRHP RAIRYDDESV NENYVASAIS CLVAREEYNF FGDKLPLWQV FRLHMIDILL NFDISKSAHQ VAMFRTKVSI KFTASTPADK QLLLTILLRA ADYSFTCRQL ALYSKWKDRM IDEFFAMGDT EKQLALTVSP FCDRELTNVD KCHVAFAEVA VKPLMTVLVL GLAPHLQKDV LDTLEANQKN LMQKLDKSD //