ID A0A086JNU3_TOXGO Unreviewed; 609 AA. AC A0A086JNU3; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 31-JUL-2019, entry version 22. DE SubName: Full=3'5'-cyclic nucleotide phosphodiesterase domain-containing protein {ECO:0000313|EMBL:KFG33811.1}; DE EC=3.1.4.17 {ECO:0000313|EMBL:KFG33811.1}; GN ORFNames=TGDOM2_258508 {ECO:0000313|EMBL:KFG33811.1}; OS Toxoplasma gondii GAB2-2007-GAL-DOM2. OC Eukaryota; Alveolata; Apicomplexa; Conoidasida; Coccidia; OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma. OX NCBI_TaxID=1130820 {ECO:0000313|EMBL:KFG33811.1}; RN [1] {ECO:0000313|EMBL:KFG33811.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=GAB2-2007-GAL-DOM2 {ECO:0000313|EMBL:KFG33811.1}; RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., RA Brunk B., Roos D., Caler E., Lorenzi H.; RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:KFG33811.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AHZU02001301; KFG33811.1; -; Genomic_DNA. DR EnsemblProtists; KFG33811; KFG33811; TGDOM2_258508. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:UniProtKB-EC. DR GO; GO:0005216; F:ion channel activity; IEA:InterPro. DR GO; GO:0007165; P:signal transduction; IEA:InterPro. DR Gene3D; 1.10.1300.10; -; 1. DR Gene3D; 1.20.120.350; -; 1. DR InterPro; IPR005821; Ion_trans_dom. DR InterPro; IPR002073; PDEase_catalytic_dom. DR InterPro; IPR036971; PDEase_catalytic_dom_sf. DR InterPro; IPR027359; Volt_channel_dom_sf. DR Pfam; PF00520; Ion_trans; 1. DR Pfam; PF00233; PDEase_I; 1. DR PROSITE; PS51845; PDEASE_I_2; 1. PE 4: Predicted; KW Hydrolase {ECO:0000313|EMBL:KFG33811.1}; KW Membrane {ECO:0000256|SAAS:SAAS00460873, ECO:0000256|SAM:Phobius}; KW Transmembrane {ECO:0000256|SAAS:SAAS00460807, KW ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00461080, KW ECO:0000256|SAM:Phobius}. FT TRANSMEM 48 73 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 264 608 PDEase. {ECO:0000259|PROSITE:PS51845}. FT REGION 146 196 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 233 263 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 159 196 Polar. {ECO:0000256|SAM:MobiDB-lite}. SQ SEQUENCE 609 AA; 68371 MW; 446ACC29FD6E172B CRC64; MHISCVKGRI VARQIDNVFT VIFAIEVLGK FVSYGLEYLQ DPIESFDTIV VLTSFTLLVL GFYVSGIGLL RILRLLSALA LLHKYPDSKE KRPELSAGNS SKLEKASSIV EGLLTNVHIP KYFKTELEWV WDSILANKVY DSHVVENEEE EEDQATETII AGSDASRKTQ AAVRASRAQS RASKLPHGSS SMVVGTTNGR ISGQILETLR EPDPRMMDAA LYKSETRNLD PLTATVGGMK NSPSMFAKGS KSSNMMGSSA SKSFRTERNK KAIDIISVLY QASQITGAEQ EQVNEAMRPF DEWQWDALHA GDVCDMNLLP VVFVRAIATF PTIMTKFNFD LDRLFDFLKV VQTSFQKNVK FHCAAHTADM IQAMHYFLTI GKLGALLSEY DVFLCHFCAL VCHFGHPGVT NTFLVKSRHP RAIRYDDESV NENYVASAIS CLVAREEYNF FGDKLPLWQV FRLHMIDILL NFDISKSAHQ VAMFRTKVSI KFTASTPADK QLLLTILLRA ADYSFTCRQL ALYSKWKDRM IDEFFAMGDT EKQLALTVSP FCDRELTNVD KCHVAFAEVA VKPLMTVLVL GLAPHLQKDV LDTLEANQKN LMQKLDKSD //