ID A0A081R422_STROR Unreviewed; 250 AA. AC A0A081R422; A0A0N5E9F1; D4FQD3; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 22-FEB-2023, entry version 42. DE SubName: Full=Accessory gene regulator protein A {ECO:0000313|EMBL:RSI72448.1}; DE SubName: Full=DNA-binding response regulator {ECO:0000313|EMBL:OJG02333.1}; DE SubName: Full=LytTr DNA-binding domain protein {ECO:0000313|EMBL:KEQ49945.1}; DE SubName: Full=Response regulator of the competence regulon ComE {ECO:0000313|EMBL:KXT81600.1}; DE SubName: Full=Response regulator transcription factor {ECO:0000313|EMBL:QQB99482.1}; GN Name=agrA {ECO:0000313|EMBL:RSI72448.1}; GN Synonyms=agrA_2 {ECO:0000313|EMBL:RSK12787.1}; GN ORFNames=BBP19_05890 {ECO:0000313|EMBL:OJG02333.1}, D8804_06465 GN {ECO:0000313|EMBL:RSK08731.1}, D8835_07855 GN {ECO:0000313|EMBL:RSK14137.1}, D8846_00010 GN {ECO:0000313|EMBL:RSK20300.1}, D8850_08770 GN {ECO:0000313|EMBL:RSK12787.1}, D8858_05865 GN {ECO:0000313|EMBL:RSI75671.1}, D8860_01360 GN {ECO:0000313|EMBL:RSI72448.1}, I6H78_05400 GN {ECO:0000313|EMBL:QQC34689.1}, I6I32_05455 GN {ECO:0000313|EMBL:QQB99482.1}, SK143_1889 GN {ECO:0000313|EMBL:KEQ49945.1}, SORDD14_01205 GN {ECO:0000313|EMBL:KXT81600.1}, SORDD20_00206 GN {ECO:0000313|EMBL:KXT96672.1}, SORDD25_01487 GN {ECO:0000313|EMBL:KXU07563.1}, SORDD27_01772 GN {ECO:0000313|EMBL:KXT93693.1}, SORDD30_01523 GN {ECO:0000313|EMBL:KXT97486.1}; OS Streptococcus oralis. OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; OC Streptococcus. OX NCBI_TaxID=1303 {ECO:0000313|EMBL:KEQ49945.1, ECO:0000313|Proteomes:UP000028098}; RN [1] {ECO:0000313|EMBL:KEQ49945.1, ECO:0000313|Proteomes:UP000028098} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SK143 {ECO:0000313|EMBL:KEQ49945.1, RC ECO:0000313|Proteomes:UP000028098}; RA Daugherty S.C., Tallon L.J., Sadzewicz L., Kilian M., Tettelin H.; RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Proteomes:UP000070220, ECO:0000313|Proteomes:UP000070340} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DD14 {ECO:0000313|EMBL:KXT81600.1, RC ECO:0000313|Proteomes:UP000070497}, DD20 {ECO:0000313|EMBL:KXT96672.1, RC ECO:0000313|Proteomes:UP000070340}, DD25 {ECO:0000313|EMBL:KXU07563.1, RC ECO:0000313|Proteomes:UP000071369}, DD27 {ECO:0000313|EMBL:KXT93693.1, RC ECO:0000313|Proteomes:UP000072363}, and DD30 RC {ECO:0000313|EMBL:KXT97486.1, ECO:0000313|Proteomes:UP000070220}; RA Denapaite D., Rieger M., Koendgen S., Brueckner R., Ochigava I., RA Kappeler P., Maetz-Rensing K., Leendertz F., Hakenbeck R.; RT "Highly variable Streptococcus oralis are common among viridans RT streptococci isolated from primates."; RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:OJG02333.1, ECO:0000313|Proteomes:UP000183671} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SC15-3744 {ECO:0000313|EMBL:OJG02333.1, RC ECO:0000313|Proteomes:UP000183671}; RA Kanji J.N., Bharat A., Naidu P., Martin I., Mulvey M.R., Panaro C.D.; RT "A clinical isolate of carbapenem-resistant Streptococcus oralis with RT altered penicillin binding proteins."; RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|Proteomes:UP000270438, ECO:0000313|Proteomes:UP000272687} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BCA1 {ECO:0000313|EMBL:RSK08731.1, RC ECO:0000313|Proteomes:UP000279863}, BCC02 RC {ECO:0000313|EMBL:RSK14137.1, ECO:0000313|Proteomes:UP000270438}, RC BCC19 {ECO:0000313|EMBL:RSI75671.1, RC ECO:0000313|Proteomes:UP000281197}, BCC50 RC {ECO:0000313|EMBL:RSI72448.1, ECO:0000313|Proteomes:UP000272687}, RC BCC58 {ECO:0000313|EMBL:RSK20300.1, RC ECO:0000313|Proteomes:UP000277548}, and KLC05 RC {ECO:0000313|EMBL:RSK12787.1, ECO:0000313|Proteomes:UP000274672}; RA Velsko I.; RT "Species Designations Belie Phenotypic and Genotypic Heterogeneity in Oral RT Streptococci."; RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases. RN [5] {ECO:0000313|Proteomes:UP000595431, ECO:0000313|Proteomes:UP000595948} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=FDAARGOS_1021 {ECO:0000313|EMBL:QQC34689.1, RC ECO:0000313|Proteomes:UP000595948}, and FDAARGOS_1075 RC {ECO:0000313|EMBL:QQB99482.1, ECO:0000313|Proteomes:UP000595431}; RA Sproer C., Gronow S., Severitt S., Schroder I., Tallon L., Sadzewicz L., RA Zhao X., Boylan J., Ott S., Bowen H., Vavikolanu K., Mehta A., RA Aluvathingal J., Nadendla S., Lowell S., Myers T., Yan Y., Sichtig H.; RT "FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS): RT Supporting development and validation of Infectious Disease Dx tests."; RL Submitted (DEC-2020) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JPGB01000006; KEQ49945.1; -; Genomic_DNA. DR EMBL; LQRI01000157; KXT81600.1; -; Genomic_DNA. DR EMBL; LQNZ01000144; KXT93693.1; -; Genomic_DNA. DR EMBL; LQOC01000058; KXT96672.1; -; Genomic_DNA. DR EMBL; LQRP01000048; KXT97486.1; -; Genomic_DNA. DR EMBL; LQZC01000011; KXU07563.1; -; Genomic_DNA. DR EMBL; MBDM01000008; OJG02333.1; -; Genomic_DNA. DR EMBL; CP066041; QQB99482.1; -; Genomic_DNA. DR EMBL; CP066059; QQC34689.1; -; Genomic_DNA. DR EMBL; RJNM01000001; RSI72448.1; -; Genomic_DNA. DR EMBL; RJNO01000012; RSI75671.1; -; Genomic_DNA. DR EMBL; RJVZ01000009; RSK08731.1; -; Genomic_DNA. DR EMBL; RMVI01000005; RSK12787.1; -; Genomic_DNA. DR EMBL; RMVL01000013; RSK14137.1; -; Genomic_DNA. DR EMBL; RMVJ01000001; RSK20300.1; -; Genomic_DNA. DR RefSeq; WP_000866079.1; NZ_SSNB01000001.1. DR STRING; 1303.SORDD17_01792; -. DR EnsemblBacteria; KEQ49945; KEQ49945; SK143_1889. DR EnsemblBacteria; KXT81600; KXT81600; SORDD14_01205. DR EnsemblBacteria; KXT93693; KXT93693; SORDD27_01772. DR EnsemblBacteria; KXT97486; KXT97486; SORDD30_01523. DR EnsemblBacteria; KXU07563; KXU07563; SORDD25_01487. DR EnsemblBacteria; OJG02333; OJG02333; BBP19_05890. DR GeneID; 49600697; -. DR PATRIC; fig|1303.44.peg.1811; -. DR Proteomes; UP000028098; Unassembled WGS sequence. DR Proteomes; UP000070220; Unassembled WGS sequence. DR Proteomes; UP000070340; Unassembled WGS sequence. DR Proteomes; UP000070497; Unassembled WGS sequence. DR Proteomes; UP000071369; Unassembled WGS sequence. DR Proteomes; UP000072363; Unassembled WGS sequence. DR Proteomes; UP000183671; Unassembled WGS sequence. DR Proteomes; UP000270438; Unassembled WGS sequence. DR Proteomes; UP000272687; Unassembled WGS sequence. DR Proteomes; UP000274672; Unassembled WGS sequence. DR Proteomes; UP000277548; Unassembled WGS sequence. DR Proteomes; UP000279863; Unassembled WGS sequence. DR Proteomes; UP000281197; Unassembled WGS sequence. DR Proteomes; UP000595431; Chromosome. DR Proteomes; UP000595948; Chromosome. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro. DR CDD; cd17533; REC_LytTR_AgrA-like; 1. DR Gene3D; 3.40.50.2300; -; 1. DR Gene3D; 2.40.50.1020; LytTr DNA-binding domain; 1. DR InterPro; IPR011006; CheY-like_superfamily. DR InterPro; IPR046947; LytR-like. DR InterPro; IPR007492; LytTR_DNA-bd_dom. DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver. DR PANTHER; PTHR37299:SF3; STAGE 0 SPORULATION PROTEIN A HOMOLOG; 1. DR PANTHER; PTHR37299; TRANSCRIPTIONAL REGULATOR-RELATED; 1. DR Pfam; PF04397; LytTR; 1. DR Pfam; PF00072; Response_reg; 1. DR SMART; SM00850; LytTR; 1. DR SMART; SM00448; REC; 1. DR SUPFAM; SSF52172; CheY-like; 1. DR PROSITE; PS50930; HTH_LYTTR; 1. DR PROSITE; PS50110; RESPONSE_REGULATORY; 1. PE 4: Predicted; KW DNA-binding {ECO:0000313|EMBL:KEQ49945.1}; KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169}. FT DOMAIN 2..125 FT /note="Response regulatory" FT /evidence="ECO:0000259|PROSITE:PS50110" FT DOMAIN 142..246 FT /note="HTH LytTR-type" FT /evidence="ECO:0000259|PROSITE:PS50930" FT MOD_RES 58 FT /note="4-aspartylphosphate" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169" SQ SEQUENCE 250 AA; 29884 MW; 303E18B4B22EBE5B CRC64; MKVLILEDVI EHQVRLERIL NEISEESNIP ISYKTTGKVR EFKEYIENDE VNQLYFLDID IHGIEKKGFE VAQFIRHHNP YAIIVFITSR SEFATLTYKY QVSALDFVDK DINDELFKKR IEQSIFYTKS MLLENEDVVD YFDYNYKGND LKIPYHDILY IETTGVSHKL RIIGKNFAKE FYGTMTDIQE KDKHTQRFYC SHKSFLVNVG NVREIDRKNL EVVFYEDHRC PITRLKVRKL KDILEKKSKK //