ID A0A081R422_STROR Unreviewed; 250 AA. AC A0A081R422; A0A0N5E9F1; D4FQD3; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 12-AUG-2020, entry version 35. DE SubName: Full=Accessory gene regulator protein A {ECO:0000313|EMBL:RSI59664.1}; DE SubName: Full=DNA-binding response regulator {ECO:0000313|EMBL:OJG02333.1}; DE SubName: Full=LytTr DNA-binding domain protein {ECO:0000313|EMBL:KEQ49945.1}; DE SubName: Full=Response regulator of the competence regulon ComE {ECO:0000313|EMBL:KXT81600.1}; GN Name=agrA {ECO:0000313|EMBL:RSI72448.1}; GN Synonyms=agrA_2 {ECO:0000313|EMBL:RSI59664.1}; GN ORFNames=BBP19_05890 {ECO:0000313|EMBL:OJG02333.1}, D8804_06465 GN {ECO:0000313|EMBL:RSK08731.1}, D8835_07855 GN {ECO:0000313|EMBL:RSK14137.1}, D8846_00010 GN {ECO:0000313|EMBL:RSK20300.1}, D8858_05865 GN {ECO:0000313|EMBL:RSI75671.1}, D8860_01360 GN {ECO:0000313|EMBL:RSI72448.1}, D8864_08910 GN {ECO:0000313|EMBL:RSI59664.1}, SK143_1889 GN {ECO:0000313|EMBL:KEQ49945.1}, SORDD14_01205 GN {ECO:0000313|EMBL:KXT81600.1}, SORDD20_00206 GN {ECO:0000313|EMBL:KXT96672.1}, SORDD25_01487 GN {ECO:0000313|EMBL:KXU07563.1}, SORDD27_01772 GN {ECO:0000313|EMBL:KXT93693.1}, SORDD30_01523 GN {ECO:0000313|EMBL:KXT97486.1}; OS Streptococcus oralis. OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; OC Streptococcus. OX NCBI_TaxID=1303 {ECO:0000313|EMBL:KEQ49945.1, ECO:0000313|Proteomes:UP000028098}; RN [1] {ECO:0000313|EMBL:KEQ49945.1, ECO:0000313|Proteomes:UP000028098} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SK143 {ECO:0000313|EMBL:KEQ49945.1, RC ECO:0000313|Proteomes:UP000028098}; RA Daugherty S.C., Tallon L.J., Sadzewicz L., Kilian M., Tettelin H.; RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Proteomes:UP000070220, ECO:0000313|Proteomes:UP000070340, ECO:0000313|Proteomes:UP000070497} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DD14 {ECO:0000313|EMBL:KXT81600.1, RC ECO:0000313|Proteomes:UP000070497}, DD20 {ECO:0000313|EMBL:KXT96672.1, RC ECO:0000313|Proteomes:UP000070340}, DD25 {ECO:0000313|EMBL:KXU07563.1, RC ECO:0000313|Proteomes:UP000071369}, DD27 {ECO:0000313|EMBL:KXT93693.1, RC ECO:0000313|Proteomes:UP000072363}, and DD30 RC {ECO:0000313|EMBL:KXT97486.1, ECO:0000313|Proteomes:UP000070220}; RA Denapaite D., Rieger M., Koendgen S., Brueckner R., Ochigava I., RA Kappeler P., Maetz-Rensing K., Leendertz F., Hakenbeck R.; RT "Highly variable Streptococcus oralis are common among viridans RT streptococci isolated from primates."; RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:OJG02333.1, ECO:0000313|Proteomes:UP000183671} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SC15-3744 {ECO:0000313|EMBL:OJG02333.1, RC ECO:0000313|Proteomes:UP000183671}; RA Kanji J.N., Bharat A., Naidu P., Martin I., Mulvey M.R., Panaro C.D.; RT "A clinical isolate of carbapenem-resistant Streptococcus oralis with RT altered penicillin binding proteins."; RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|Proteomes:UP000270438, ECO:0000313|Proteomes:UP000272687, ECO:0000313|Proteomes:UP000273474} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BCA1 {ECO:0000313|EMBL:RSK08731.1, RC ECO:0000313|Proteomes:UP000279863}, BCA21 RC {ECO:0000313|EMBL:RSI59664.1, ECO:0000313|Proteomes:UP000273474}, RC BCC02 {ECO:0000313|EMBL:RSK14137.1, RC ECO:0000313|Proteomes:UP000270438}, BCC19 RC {ECO:0000313|EMBL:RSI75671.1, ECO:0000313|Proteomes:UP000281197}, RC BCC50 {ECO:0000313|EMBL:RSI72448.1, RC ECO:0000313|Proteomes:UP000272687}, and BCC58 RC {ECO:0000313|EMBL:RSK20300.1, ECO:0000313|Proteomes:UP000277548}; RA Velsko I.; RT "Species Designations Belie Phenotypic and Genotypic Heterogeneity in Oral RT Streptococci."; RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ CC whole genome shotgun (WGS) entry which is preliminary data. CC {ECO:0000313|EMBL:KEQ49945.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JPGB01000006; KEQ49945.1; -; Genomic_DNA. DR EMBL; LQRI01000157; KXT81600.1; -; Genomic_DNA. DR EMBL; LQNZ01000144; KXT93693.1; -; Genomic_DNA. DR EMBL; LQOC01000058; KXT96672.1; -; Genomic_DNA. DR EMBL; LQRP01000048; KXT97486.1; -; Genomic_DNA. DR EMBL; LQZC01000011; KXU07563.1; -; Genomic_DNA. DR EMBL; MBDM01000008; OJG02333.1; -; Genomic_DNA. DR EMBL; RJNI01000008; RSI59664.1; -; Genomic_DNA. DR EMBL; RJNM01000001; RSI72448.1; -; Genomic_DNA. DR EMBL; RJNO01000012; RSI75671.1; -; Genomic_DNA. DR EMBL; RJVZ01000009; RSK08731.1; -; Genomic_DNA. DR EMBL; RMVL01000013; RSK14137.1; -; Genomic_DNA. DR EMBL; RMVJ01000001; RSK20300.1; -; Genomic_DNA. DR RefSeq; WP_000866079.1; NZ_SSNB01000001.1. DR EnsemblBacteria; KEQ44523; KEQ44523; SK141_1907. DR EnsemblBacteria; KEQ49945; KEQ49945; SK143_1889. DR EnsemblBacteria; KXT81600; KXT81600; SORDD14_01205. DR EnsemblBacteria; KXT93693; KXT93693; SORDD27_01772. DR EnsemblBacteria; KXT96672; KXT96672; SORDD20_00206. DR EnsemblBacteria; KXT97486; KXT97486; SORDD30_01523. DR EnsemblBacteria; KXU07563; KXU07563; SORDD25_01487. DR GeneID; 49600697; -. DR PATRIC; fig|1303.44.peg.1811; -. DR Proteomes; UP000028098; Unassembled WGS sequence. DR Proteomes; UP000070220; Unassembled WGS sequence. DR Proteomes; UP000070340; Unassembled WGS sequence. DR Proteomes; UP000070497; Unassembled WGS sequence. DR Proteomes; UP000071369; Unassembled WGS sequence. DR Proteomes; UP000072363; Unassembled WGS sequence. DR Proteomes; UP000183671; Unassembled WGS sequence. DR Proteomes; UP000270438; Unassembled WGS sequence. DR Proteomes; UP000272687; Unassembled WGS sequence. DR Proteomes; UP000273474; Unassembled WGS sequence. DR Proteomes; UP000277548; Unassembled WGS sequence. DR Proteomes; UP000279863; Unassembled WGS sequence. DR Proteomes; UP000281197; Unassembled WGS sequence. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro. DR CDD; cd00156; REC; 1. DR InterPro; IPR011006; CheY-like_superfamily. DR InterPro; IPR007492; LytTR_DNA-bd_dom. DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver. DR Pfam; PF04397; LytTR; 1. DR Pfam; PF00072; Response_reg; 1. DR SMART; SM00850; LytTR; 1. DR SMART; SM00448; REC; 1. DR SUPFAM; SSF52172; SSF52172; 1. DR PROSITE; PS50930; HTH_LYTTR; 1. DR PROSITE; PS50110; RESPONSE_REGULATORY; 1. PE 4: Predicted; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:KEQ49945.1}; KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}. FT DOMAIN 2..125 FT /note="Response regulatory" FT /evidence="ECO:0000259|PROSITE:PS50110" FT DOMAIN 142..246 FT /note="HTH LytTR-type" FT /evidence="ECO:0000259|PROSITE:PS50930" FT MOD_RES 58 FT /note="4-aspartylphosphate" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169" SQ SEQUENCE 250 AA; 29884 MW; 303E18B4B22EBE5B CRC64; MKVLILEDVI EHQVRLERIL NEISEESNIP ISYKTTGKVR EFKEYIENDE VNQLYFLDID IHGIEKKGFE VAQFIRHHNP YAIIVFITSR SEFATLTYKY QVSALDFVDK DINDELFKKR IEQSIFYTKS MLLENEDVVD YFDYNYKGND LKIPYHDILY IETTGVSHKL RIIGKNFAKE FYGTMTDIQE KDKHTQRFYC SHKSFLVNVG NVREIDRKNL EVVFYEDHRC PITRLKVRKL KDILEKKSKK //