ID A0A078MBE6_9STAP Unreviewed; 493 AA. AC A0A078MBE6; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 27-MAR-2024, entry version 36. DE SubName: Full=Multidrug export protein EmrB {ECO:0000313|EMBL:CEA03620.1}; GN Name=emrB_3 {ECO:0000313|EMBL:CEA03620.1}; GN ORFNames=BN1048_02151 {ECO:0000313|EMBL:CEA03620.1}; OS Jeotgalicoccus saudimassiliensis. OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae; OC Jeotgalicoccus. OX NCBI_TaxID=1461582 {ECO:0000313|EMBL:CEA03620.1, ECO:0000313|Proteomes:UP000044136}; RN [1] {ECO:0000313|EMBL:CEA03620.1, ECO:0000313|Proteomes:UP000044136} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=13MG44_air {ECO:0000313|EMBL:CEA03620.1, RC ECO:0000313|Proteomes:UP000044136}; RA Urmite Genomes Urmite Genomes; RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein CC {ECO:0000256|ARBA:ARBA00004141}. CC -!- SIMILARITY: Belongs to the major facilitator superfamily. EmrB family. CC {ECO:0000256|ARBA:ARBA00008537}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CCSE01000001; CEA03620.1; -; Genomic_DNA. DR RefSeq; WP_035811090.1; NZ_CCSE01000001.1. DR AlphaFoldDB; A0A078MBE6; -. DR STRING; 1461582.BN1048_02151; -. DR eggNOG; COG2814; Bacteria. DR HOGENOM; CLU_000960_28_0_9; -. DR OrthoDB; 9816041at2; -. DR Proteomes; UP000044136; Unassembled WGS sequence. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro. DR CDD; cd17503; MFS_LmrB_MDR_like; 1. DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1. DR Gene3D; 1.20.1720.10; Multidrug resistance protein D; 1. DR InterPro; IPR004638; EmrB-like. DR InterPro; IPR011701; MFS. DR InterPro; IPR020846; MFS_dom. DR InterPro; IPR036259; MFS_trans_sf. DR NCBIfam; TIGR00711; efflux_EmrB; 1. DR PANTHER; PTHR42718:SF47; DRUG EFFLUX PUMP JEFA; 1. DR PANTHER; PTHR42718; MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC; 1. DR Pfam; PF07690; MFS_1; 1. DR PRINTS; PR01036; TCRTETB. DR SUPFAM; SSF103473; MFS general substrate transporter; 1. DR PROSITE; PS50850; MFS; 1. PE 3: Inferred from homology; KW Cell membrane {ECO:0000256|ARBA:ARBA00022475}; KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius}; KW Reference proteome {ECO:0000313|Proteomes:UP000044136}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}. FT TRANSMEM 12..31 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 51..71 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 78..102 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 138..159 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 165..186 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 198..217 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 223..245 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 266..291 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 303..324 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 331..350 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 356..378 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 399..422 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT TRANSMEM 442..464 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT DOMAIN 13..469 FT /note="Major facilitator superfamily (MFS) profile" FT /evidence="ECO:0000259|PROSITE:PS50850" SQ SEQUENCE 493 AA; 53323 MW; ABDDF22E00E5466A CRC64; MSEITQKKPD YRLIIILLSG AFISFLSNTF LNVALPAIKN DFGISTSAVQ WVSTSYMLVS GIIIPTTAYL MQKFSAKTLF LAAMSLFLAG TLVAGFSPTF IVLILGRMIQ ATGSAMLMPL LMNIMITSFP PDKRGTAMGL FSLVMFFAPA IGPTLSGIVV ENYSWHMLFY MMVPVLVIVL AVGFWQLPDV QQHREAHIDI YSIVLSTIGF GGVLYGLSSA GEYGLASSSV LIPLFLGLAA VTLYVMRQFK LEHPMLDFRV YKYSMYTIAS LIIGAANMAL FAGMILIPIF MQDIQGLSPL DTGLLMLPGA LIMGLMSPVS GKLFDIYGPK VMAITGLTLA VVTTFFLSRL EVDTSFTYLL TIYMIRALGM TMVNTPVMTN GMNSLPAHLT PHGSSLNSML NQVSGSIGIA LLITVMQTYT NITVSKMDNP TEAMINQATL EGINLSFLVG TCFLGLALAA AFFLKQSSSG ETIGKGLAKA RPISDESKKL SRD //