ID A0A077S1H9_MOUSE Unreviewed; 160 AA. AC A0A077S1H9; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 29-MAY-2024, entry version 67. DE SubName: Full=Lysozyme e {ECO:0000313|EMBL:CDM98777.1}; GN Name=Spaca5 {ECO:0000313|MGI:MGI:2685564}; GN Synonyms=Lyze {ECO:0000313|EMBL:CDM98777.1}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:CDM98777.1}; RN [1] {ECO:0007829|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and expression."; RL Cell 143:1174-1189(2010). RN [2] {ECO:0000313|EMBL:CDM98777.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=N/A {ECO:0000313|EMBL:CDM98777.1}; RX PubMed=26484105; DOI=10.1016/j.gdata.2014.08.003; RA Premzl M.; RT "Third party annotation gene data set of eutherian lysozyme genes."; RL Genom Data 2:258-260(2014). RN [3] {ECO:0000313|EMBL:CDM98777.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=N/A {ECO:0000313|EMBL:CDM98777.1}; RX PubMed=26862561; DOI=10.1016/j.dib.2015.11.056; RA Premzl M.; RT "Curated eutherian third party data gene data sets."; RL Data Brief 6:208-213(2016). RN [4] {ECO:0000313|EMBL:CDM98777.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=N/A {ECO:0000313|EMBL:CDM98777.1}; RX DOI=10.1016/j.genrep.2019.100414; RA Premzl M.; RT "Eutherian third-party data gene collections."; RL Gene Rep 16:100414-100414(2019). CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 22 family. CC {ECO:0000256|RuleBase:RU004440}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HG931776; CDM98777.1; -; Genomic_DNA. DR RefSeq; NP_001078862.1; NM_001085393.2. DR AlphaFoldDB; A0A077S1H9; -. DR SMR; A0A077S1H9; -. DR GeneID; 278203; -. DR KEGG; mmu:278203; -. DR AGR; MGI:2685564; -. DR CTD; 389852; -. DR MGI; MGI:2685564; Spaca5. DR VEuPathDB; HostDB:ENSMUSG00000037167; -. DR HOGENOM; CLU_111620_0_1_1; -. DR OMA; SAWWCNN; -. DR OrthoDB; 5344399at2759; -. DR PhylomeDB; A0A077S1H9; -. DR BioGRID-ORCS; 278203; 1 hit in 76 CRISPR screens. DR ExpressionAtlas; A0A077S1H9; baseline and differential. DR GO; GO:0001669; C:acrosomal vesicle; IEA:TreeGrafter. DR GO; GO:0036126; C:sperm flagellum; IEA:TreeGrafter. DR GO; GO:0003796; F:lysozyme activity; IEA:InterPro. DR GO; GO:0007342; P:fusion of sperm to egg plasma membrane involved in single fertilization; IEA:TreeGrafter. DR CDD; cd16897; LYZ_C; 1. DR Gene3D; 1.10.530.10; -; 1. DR InterPro; IPR001916; Glyco_hydro_22. DR InterPro; IPR000974; Glyco_hydro_22_lys. DR InterPro; IPR023346; Lysozyme-like_dom_sf. DR PANTHER; PTHR11407; LYSOZYME C; 1. DR PANTHER; PTHR11407:SF31; SPERM ACROSOME-ASSOCIATED PROTEIN 5; 1. DR Pfam; PF00062; Lys; 1. DR PRINTS; PR00137; LYSOZYME. DR PRINTS; PR00135; LYZLACT. DR SMART; SM00263; LYZ1; 1. DR SUPFAM; SSF53955; Lysozyme-like; 1. DR PROSITE; PS51348; GLYCOSYL_HYDROL_F22_2; 1. PE 1: Evidence at protein level; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..21 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 22..160 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5015028437" SQ SEQUENCE 160 AA; 18005 MW; 6B29416231FA5C1E CRC64; MKVCSIVVVI LAVLLIAKLD AKIYERCELA KKLEEAGLDG FKGYTVGDWL CVAHYESGFD TSFVDHNPDG SSEYGIFQLN SAWWCNNGIT PTQNLCNIDC NDLLNRHILD DIICAKRVAS SHKSMKAWDS WTQHCAGHDL SEWLKGCSVR LKTDSSYNNW //