ID A0A077S1H9_MOUSE Unreviewed; 160 AA. AC A0A077S1H9; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 18-JAN-2017, entry version 25. DE SubName: Full=Lysozyme e {ECO:0000313|EMBL:CDM98777.1}; DE SubName: Full=MCG117707 {ECO:0000313|EMBL:EDL00726.1}; GN Name=Spaca5 {ECO:0000313|MGI:MGI:2685564}; GN Synonyms=Lyze {ECO:0000313|EMBL:CDM98777.1}; GN ORFNames=mCG_117707 {ECO:0000313|EMBL:EDL00726.1}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:CDM98777.1}; RN [1] {ECO:0000313|EMBL:EDL00726.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Mixed {ECO:0000313|EMBL:EDL00726.1}; RX PubMed=12040188; DOI=10.1126/science.1069193; RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., RA Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., RA Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W., RA Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., RA Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., RA Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., RA Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., RA Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., RA Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., RA Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., RA Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., RA Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., RA Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., RA Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., RA Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., RA Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., RA Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., RA Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., RA Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., RA Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., RA Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., RA Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., RA Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., RA Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., RA Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., RA Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., RA Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., RA Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., RA Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., RA Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., RA Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., RA Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.; RT "A comparison of whole-genome shotgun-derived mouse chromosome 16 and RT the human genome."; RL Science 296:1661-1671(2002). RN [2] {ECO:0000313|EMBL:EDL00726.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Mixed {ECO:0000313|EMBL:EDL00726.1}; RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.; RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). RN [4] {ECO:0000313|EMBL:CDM98777.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=N/A {ECO:0000313|EMBL:CDM98777.1}; RX PubMed=26484105; DOI=10.1016/j.gdata.2014.08.003; RA Premzl M.; RT "Third party annotation gene data set of eutherian lysozyme genes."; RL Genom Data 2:258-260(2014). RN [5] {ECO:0000313|EMBL:CDM98777.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=N/A {ECO:0000313|EMBL:CDM98777.1}; RX PubMed=26862561; DOI=10.1016/j.dib.2015.11.056; RA Premzl M.; RT "Curated eutherian third party data gene data sets."; RL Data Brief 6:208-213(2016). CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 22 family. CC {ECO:0000256|RuleBase:RU004440, ECO:0000256|SAAS:SAAS00581266}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; HG931776; CDM98777.1; -; Genomic_DNA. DR EMBL; CH466625; EDL00726.1; -; Genomic_DNA. DR RefSeq; NP_001078862.1; NM_001085393.2. DR STRING; 10090.ENSMUSP00000048721; -. DR GeneID; 278203; -. DR KEGG; mmu:278203; -. DR CTD; 389852; -. DR MGI; MGI:2685564; Spaca5. DR eggNOG; ENOG410IT6F; Eukaryota. DR eggNOG; ENOG4111EG8; LUCA. DR KO; K01185; -. DR OMA; TQNLCHM; -. DR OrthoDB; EOG091G0R9V; -. DR GO; GO:0003796; F:lysozyme activity; IEA:InterPro. DR CDD; cd00119; LYZ1; 1. DR InterPro; IPR001916; Glyco_hydro_22. DR InterPro; IPR000974; Glyco_hydro_22_lys. DR InterPro; IPR023346; Lysozyme-like_dom. DR InterPro; IPR030064; LYZL5. DR PANTHER; PTHR11407:SF31; PTHR11407:SF31; 1. DR Pfam; PF00062; Lys; 1. DR PRINTS; PR00137; LYSOZYME. DR PRINTS; PR00135; LYZLACT. DR SMART; SM00263; LYZ1; 1. DR SUPFAM; SSF53955; SSF53955; 1. DR PROSITE; PS51348; LACTALBUMIN_LYSOZYME_2; 1. PE 1: Evidence at protein level; KW Disulfide bond {ECO:0000256|SAAS:SAAS00108962}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 21 {ECO:0000256|SAM:SignalP}. FT CHAIN 22 160 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5008819407. SQ SEQUENCE 160 AA; 18005 MW; 6B29416231FA5C1E CRC64; MKVCSIVVVI LAVLLIAKLD AKIYERCELA KKLEEAGLDG FKGYTVGDWL CVAHYESGFD TSFVDHNPDG SSEYGIFQLN SAWWCNNGIT PTQNLCNIDC NDLLNRHILD DIICAKRVAS SHKSMKAWDS WTQHCAGHDL SEWLKGCSVR LKTDSSYNNW //