ID A0A077S1H9_MOUSE Unreviewed; 160 AA. AC A0A077S1H9; DT 29-OCT-2014, integrated into UniProtKB/TrEMBL. DT 29-OCT-2014, sequence version 1. DT 06-JUL-2016, entry version 20. DE SubName: Full=Lysozyme e {ECO:0000313|EMBL:CDM98777.1}; DE SubName: Full=MCG117707 {ECO:0000313|EMBL:EDL00726.1}; DE SubName: Full=Sperm acrosome-associated protein 5 {ECO:0000313|Ensembl:ENSMUSP00000048721}; GN Name=Spaca5 {ECO:0000313|Ensembl:ENSMUSP00000048721, GN ECO:0000313|MGI:MGI:2685564}; GN Synonyms=Lyze {ECO:0000313|EMBL:CDM98777.1}; GN ORFNames=mCG_117707 {ECO:0000313|EMBL:EDL00726.1}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:CDM98777.1}; RN [1] {ECO:0000313|EMBL:EDL00726.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Mixed {ECO:0000313|EMBL:EDL00726.1}; RX PubMed=12040188; DOI=10.1126/science.1069193; RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., RA Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., RA Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W., RA Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., RA Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., RA Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., RA Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., RA Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., RA Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., RA Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., RA Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., RA Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., RA Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., RA Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., RA Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., RA Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., RA Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., RA Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., RA Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., RA Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., RA Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., RA Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., RA Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., RA Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., RA Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., RA Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., RA Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., RA Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., RA Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., RA Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., RA Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., RA Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.; RT "A comparison of whole-genome shotgun-derived mouse chromosome 16 and RT the human genome."; RL Science 296:1661-1671(2002). RN [2] {ECO:0000313|EMBL:EDL00726.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Mixed {ECO:0000313|EMBL:EDL00726.1}; RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.; RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|Ensembl:ENSMUSP00000048721, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000048721, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [4] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and RT expression."; RL Cell 143:1174-1189(2010). RN [5] {ECO:0000313|EMBL:CDM98777.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=N/A {ECO:0000313|EMBL:CDM98777.1}; RX PubMed=26484105; DOI=10.1016/j.gdata.2014.08.003; RA Premzl M.; RT "Third party annotation gene data set of eutherian lysozyme genes."; RL Genomics Data 2:258-260(2014). RN [6] {ECO:0000313|Ensembl:ENSMUSP00000048721} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000048721}; RG Ensembl; RL Submitted (AUG-2015) to UniProtKB. RN [7] {ECO:0000313|EMBL:CDM98777.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=N/A {ECO:0000313|EMBL:CDM98777.1}; RX PubMed=26862561; DOI=10.1016/j.dib.2015.11.056; RA Premzl M.; RT "Curated eutherian third party data gene data sets."; RL Data Brief 6:208-213(2016). CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 22 family. CC {ECO:0000256|RuleBase:RU004440, ECO:0000256|SAAS:SAAS00581266}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL671853; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; HG931776; CDM98777.1; -; Genomic_DNA. DR EMBL; CH466625; EDL00726.1; -; Genomic_DNA. DR RefSeq; NP_001078862.1; NM_001085393.2. DR STRING; 10090.ENSMUSP00000048721; -. DR Ensembl; ENSMUST00000040437; ENSMUSP00000048721; ENSMUSG00000037167. DR GeneID; 278203; -. DR KEGG; mmu:278203; -. DR CTD; 389852; -. DR MGI; MGI:2685564; Spaca5. DR eggNOG; ENOG410IT6F; Eukaryota. DR eggNOG; ENOG4111EG8; LUCA. DR KO; K01185; -. DR OMA; TQNLCHM; -. DR Proteomes; UP000000589; Chromosome X. DR GO; GO:0003796; F:lysozyme activity; IEA:InterPro. DR InterPro; IPR001916; Glyco_hydro_22. DR InterPro; IPR000974; Glyco_hydro_22_lys. DR InterPro; IPR023346; Lysozyme-like_dom. DR InterPro; IPR030064; LYZL5. DR PANTHER; PTHR11407:SF31; PTHR11407:SF31; 1. DR Pfam; PF00062; Lys; 1. DR PRINTS; PR00137; LYSOZYME. DR PRINTS; PR00135; LYZLACT. DR SMART; SM00263; LYZ1; 1. DR SUPFAM; SSF53955; SSF53955; 1. DR PROSITE; PS51348; LACTALBUMIN_LYSOZYME_2; 1. PE 1: Evidence at protein level; KW Complete proteome {ECO:0000313|Proteomes:UP000000589}; KW Disulfide bond {ECO:0000256|SAAS:SAAS00472704}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 21 {ECO:0000256|SAM:SignalP}. FT CHAIN 22 160 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5007377018. SQ SEQUENCE 160 AA; 18005 MW; 6B29416231FA5C1E CRC64; MKVCSIVVVI LAVLLIAKLD AKIYERCELA KKLEEAGLDG FKGYTVGDWL CVAHYESGFD TSFVDHNPDG SSEYGIFQLN SAWWCNNGIT PTQNLCNIDC NDLLNRHILD DIICAKRVAS SHKSMKAWDS WTQHCAGHDL SEWLKGCSVR LKTDSSYNNW //