ID A0A068BFV6_MOUSE Unreviewed; 482 AA. AC A0A068BFV6; DT 01-OCT-2014, integrated into UniProtKB/TrEMBL. DT 01-OCT-2014, sequence version 1. DT 09-DEC-2015, entry version 8. DE SubName: Full=Putative retinoid X receptor beta isoform 3 {ECO:0000313|EMBL:AIC84029.1}; GN Name=Rxrb {ECO:0000313|EMBL:AIC84029.1, ECO:0000313|MGI:MGI:98215}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AIC84029.1}; RN [1] {ECO:0000313|EMBL:AIC84029.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=I/StSnEgYCit {ECO:0000313|EMBL:AIC84029.1}; RC TISSUE=Spleen {ECO:0000313|EMBL:AIC84029.1}; RA Logunova N.N., Korotetskaya M.V., Apt A.S.; RT "A QTL within the H-2 complex involved in the control of tuberculosis RT infection is the classical class II H2-Ab1 gene: identification by the RT forward genetic approach."; RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family. CC {ECO:0000256|RuleBase:RU000377}. CC -!- SIMILARITY: Contains nuclear receptor DNA-binding domain. CC {ECO:0000256|SAAS:SAAS00398720}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KJ663719; AIC84029.1; -; mRNA. DR UniGene; Mm.1243; -. DR MGI; MGI:98215; Rxrb. DR GO; GO:0005634; C:nucleus; ISO:MGI. DR GO; GO:0004886; F:9-cis retinoic acid receptor activity; IDA:MGI. DR GO; GO:0042803; F:protein homodimerization activity; IDA:MGI. DR GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:MGI. DR GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:MGI. DR GO; GO:0004879; F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding; ISO:MGI. DR GO; GO:0043565; F:sequence-specific DNA binding; IGI:MGI. DR GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro. DR GO; GO:0001228; F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; ISO:MGI. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0060038; P:cardiac muscle cell proliferation; IGI:MGI. DR GO; GO:0001701; P:in utero embryonic development; IGI:MGI. DR GO; GO:0001893; P:maternal placenta development; IGI:MGI. DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI. DR GO; GO:0048384; P:retinoic acid receptor signaling pathway; IDA:MGI. DR GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISO:GOC. DR GO; GO:0055012; P:ventricular cardiac muscle cell differentiation; IMP:MGI. DR Gene3D; 1.10.565.10; -; 1. DR Gene3D; 3.30.50.10; -; 1. DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd. DR InterPro; IPR001723; Nuclear_hrmn_rcpt. DR InterPro; IPR000003; Retinoid-X_rcpt/HNF4. DR InterPro; IPR001628; Znf_hrmn_rcpt. DR InterPro; IPR013088; Znf_NHR/GATA. DR Pfam; PF00104; Hormone_recep; 1. DR Pfam; PF00105; zf-C4; 1. DR PRINTS; PR00545; RETINOIDXR. DR PRINTS; PR00398; STRDHORMONER. DR PRINTS; PR00047; STROIDFINGER. DR SMART; SM00430; HOLI; 1. DR SMART; SM00399; ZnF_C4; 1. DR SUPFAM; SSF48508; SSF48508; 1. DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1. DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1. PE 2: Evidence at transcript level; KW DNA-binding {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00116462}; KW Metal-binding {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00116612}; KW Nucleus {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00306265}; KW Receptor {ECO:0000256|RuleBase:RU004334, ECO:0000313|EMBL:AIC84029.1}; KW Transcription {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00306222}; KW Transcription regulation {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00306243}; KW Zinc {ECO:0000256|RuleBase:RU004334, ECO:0000256|SAAS:SAAS00116516}; KW Zinc-finger {ECO:0000256|RuleBase:RU004334, KW ECO:0000256|SAAS:SAAS00116578}. FT DOMAIN 151 226 Nuclear receptor DNA-binding. FT {ECO:0000259|PROSITE:PS51030}. SQ SEQUENCE 482 AA; 51813 MW; 21178652D6D54D83 CRC64; MSWATRPPFL PPRHAAGQCG PVGVRKEMHC GMGDSGRDSR SPDSSSPNPL SQGIRPSSPP GPPLTPSAPP PPMPPPPLGS PFPVISSSMG SPGLPPPAPP GFSGPVSSPQ INSTVSLPGG GSGPPEDVKP PVLGVRGLHC PPPPGGPGAG KRLCAICGDR SSGKHYGVYS CEGCKGFFKR TIRKDLTYSC RDNKDCTVDK RQRNRCQYCR YQKCLATGMK REAVQEERQR GKDKDGDGDG AGGAPEEMPV DRILEAELAV EQKSDQGVEG PGATGGGGSS PNDPVTNICQ AADKQLFTLV EWAKRIPHFS SLPLDDQVIL LRAGWNELLI ASFSHRSIDV RDGILLATGL HVHRNSAHSA GVGAIFDRVL TELVSKMRDM RMDKTELGCL RAIILFNPDA KGLSNPGEVE ILREKVYASL ETYCKQKYPE QQGRFAKLLL RLPALRSIGL KCLEHLFFFK LIGDTPIDTF LMEMLEAPHQ LA //