ID A0A068BFV6_MOUSE Unreviewed; 482 AA. AC A0A068BFV6; DT 01-OCT-2014, integrated into UniProtKB/TrEMBL. DT 01-OCT-2014, sequence version 1. DT 08-NOV-2023, entry version 45. DE SubName: Full=Putative retinoid X receptor beta isoform 3 {ECO:0000313|EMBL:AIC84029.1}; GN Name=Rxrb {ECO:0000313|EMBL:AIC84029.1, ECO:0000313|MGI:MGI:98215}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AIC84029.1}; RN [1] {ECO:0000313|EMBL:AIC84029.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=I/StSnEgYCit {ECO:0000313|EMBL:AIC84029.1}; RC TISSUE=Spleen {ECO:0000313|EMBL:AIC84029.1}; RA Harrison E.; RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:AIC84029.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=I/StSnEgYCit {ECO:0000313|EMBL:AIC84029.1}; RC TISSUE=Spleen {ECO:0000313|EMBL:AIC84029.1}; RX PubMed=26618355; RA Logunova N., Korotetskaya M., Polshakov V., Apt A.; RT "The QTL within the H2 Complex Involved in the Control of Tuberculosis RT Infection in Mice Is the Classical Class II H2-Ab1 Gene."; RL PLoS Genet. 11:E1005672-E1005672(2015). CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}. CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family. NR2 CC subfamily. {ECO:0000256|ARBA:ARBA00006421}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KJ663719; AIC84029.1; -; mRNA. DR AlphaFoldDB; A0A068BFV6; -. DR AGR; MGI:98215; -. DR MGI; MGI:98215; Rxrb. DR ChiTaRS; Rxrb; mouse. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro. DR GO; GO:0003707; F:nuclear steroid receptor activity; IEA:InterPro. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0006351; P:DNA-templated transcription; IEA:UniProtKB-UniRule. DR CDD; cd06956; NR_DBD_RXR; 1. DR CDD; cd06943; NR_LBD_RXR_like; 1. DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1. DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1. DR InterPro; IPR035500; NHR-like_dom_sf. DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd. DR InterPro; IPR001723; Nuclear_hrmn_rcpt. DR InterPro; IPR000003; Retinoid-X_rcpt/HNF4. DR InterPro; IPR001628; Znf_hrmn_rcpt. DR InterPro; IPR013088; Znf_NHR/GATA. DR PANTHER; PTHR24083; NUCLEAR HORMONE RECEPTOR; 1. DR PANTHER; PTHR24083:SF90; RETINOIC ACID RECEPTOR RXR-BETA; 1. DR Pfam; PF00104; Hormone_recep; 1. DR Pfam; PF00105; zf-C4; 1. DR PRINTS; PR00545; RETINOIDXR. DR PRINTS; PR00398; STRDHORMONER. DR PRINTS; PR00047; STROIDFINGER. DR SMART; SM00430; HOLI; 1. DR SMART; SM00399; ZnF_C4; 1. DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1. DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1. DR PROSITE; PS51843; NR_LBD; 1. DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1. DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1. PE 2: Evidence at transcript level; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, KW ECO:0000256|RuleBase:RU004334}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334}; KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334}; KW Transcription {ECO:0000256|ARBA:ARBA00023163, KW ECO:0000256|RuleBase:RU004334}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, KW ECO:0000256|RuleBase:RU004334}; KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334}; KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}. FT DOMAIN 151..226 FT /note="Nuclear receptor" FT /evidence="ECO:0000259|PROSITE:PS51030" FT DOMAIN 245..478 FT /note="NR LBD" FT /evidence="ECO:0000259|PROSITE:PS51843" FT REGION 1..129 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 225..247 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 262..285 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 38..52 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 53..82 FT /note="Pro residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 90..104 FT /note="Pro residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 105..119 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 225..241 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 482 AA; 51813 MW; 21178652D6D54D83 CRC64; MSWATRPPFL PPRHAAGQCG PVGVRKEMHC GMGDSGRDSR SPDSSSPNPL SQGIRPSSPP GPPLTPSAPP PPMPPPPLGS PFPVISSSMG SPGLPPPAPP GFSGPVSSPQ INSTVSLPGG GSGPPEDVKP PVLGVRGLHC PPPPGGPGAG KRLCAICGDR SSGKHYGVYS CEGCKGFFKR TIRKDLTYSC RDNKDCTVDK RQRNRCQYCR YQKCLATGMK REAVQEERQR GKDKDGDGDG AGGAPEEMPV DRILEAELAV EQKSDQGVEG PGATGGGGSS PNDPVTNICQ AADKQLFTLV EWAKRIPHFS SLPLDDQVIL LRAGWNELLI ASFSHRSIDV RDGILLATGL HVHRNSAHSA GVGAIFDRVL TELVSKMRDM RMDKTELGCL RAIILFNPDA KGLSNPGEVE ILREKVYASL ETYCKQKYPE QQGRFAKLLL RLPALRSIGL KCLEHLFFFK LIGDTPIDTF LMEMLEAPHQ LA //