ID   A0A068BA71_9NEOP        Unreviewed;       265 AA.
AC   A0A068BA71;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   25-OCT-2017, entry version 14.
DE   RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU000369};
DE            EC=1.9.3.1 {ECO:0000256|RuleBase:RU000369};
DE   Flags: Fragment;
OS   Micrarchus sp. n. 2 LTD-2014.
OG   Mitochondrion {ECO:0000313|EMBL:AIC79428.1}.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Polyneoptera; Phasmatodea; Verophasmatodea;
OC   Anareolatae; Diapheromeridae; Pachymorphinae; Micrarchus.
OX   NCBI_TaxID=1448259 {ECO:0000313|EMBL:AIC79428.1};
RN   [1] {ECO:0000313|EMBL:AIC79428.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MMT004 {ECO:0000313|EMBL:AIC79388.1}, MMT027
RC   {ECO:0000313|EMBL:AIC79424.1}, MMT028 {ECO:0000313|EMBL:AIC79426.1},
RC   MMT029 {ECO:0000313|EMBL:AIC79428.1}, MMT032
RC   {ECO:0000313|EMBL:AIC79434.1}, and MMT056
RC   {ECO:0000313|EMBL:AIC79478.1};
RX   PubMed=24762129; DOI=10.1111/mec.12767;
RA   Dunning L.T., Dennis A.B., Sinclair B.J., Newcomb R.D., Buckley T.R.;
RT   "Divergent transcriptional responses to low temperature among
RT   populations of alpine and lowland species of New Zealand stick insects
RT   (Micrarchus).";
RL   Mol. Ecol. 23:2712-2726(2014).
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC       3 form the functional core of the enzyme complex. CO I is the
CC       catalytic subunit of the enzyme. Electrons originating in
CC       cytochrome c are transferred via the copper A center of subunit 2
CC       and heme A of subunit 1 to the bimetallic center formed by heme A3
CC       and copper B. {ECO:0000256|RuleBase:RU000369}.
CC   -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
CC       ferricytochrome c + 2 H(2)O. {ECO:0000256|RuleBase:RU000369}.
CC   -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC       {ECO:0000256|RuleBase:RU000369}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000256|RuleBase:RU000369}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU000369}.
CC   -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
CC       {ECO:0000256|RuleBase:RU000369}.
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DR   EMBL; KJ142656; AIC79388.1; -; Genomic_DNA.
DR   EMBL; KJ142674; AIC79424.1; -; Genomic_DNA.
DR   EMBL; KJ142675; AIC79426.1; -; Genomic_DNA.
DR   EMBL; KJ142676; AIC79428.1; -; Genomic_DNA.
DR   EMBL; KJ142679; AIC79434.1; -; Genomic_DNA.
DR   EMBL; KJ142701; AIC79478.1; -; Genomic_DNA.
DR   UniPathway; UPA00705; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.20.210.10; -; 1.
DR   InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
DR   InterPro; IPR036927; Cyt_c_oxase-like_su1_sf.
DR   InterPro; IPR000883; Cyt_C_Oxase_1.
DR   PANTHER; PTHR10422; PTHR10422; 1.
DR   Pfam; PF00115; COX1; 1.
DR   PRINTS; PR01165; CYCOXIDASEI.
DR   SUPFAM; SSF81442; SSF81442; 1.
DR   PROSITE; PS50855; COX1; 1.
PE   3: Inferred from homology;
KW   Copper {ECO:0000256|RuleBase:RU000369};
KW   Electron transport {ECO:0000256|RuleBase:RU000369};
KW   Heme {ECO:0000256|RuleBase:RU000369};
KW   Iron {ECO:0000256|RuleBase:RU000369};
KW   Membrane {ECO:0000256|RuleBase:RU000369, ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|RuleBase:RU000369};
KW   Mitochondrion {ECO:0000256|RuleBase:RU000369,
KW   ECO:0000313|EMBL:AIC79428.1};
KW   Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000369};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000369};
KW   Respiratory chain {ECO:0000256|RuleBase:RU000369};
KW   Transmembrane {ECO:0000256|RuleBase:RU000369,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU000369}.
FT   TRANSMEM     21     42       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     54     77       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     89    108       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    128    147       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    159    178       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    198    224       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1    263       COX1. {ECO:0000259|PROSITE:PS50855}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:AIC79428.1}.
SQ   SEQUENCE   265 AA;  29812 MW;  F47F4A1E3930D668 CRC64;
     GFGMISHIIA HESGKKEVFG NLGMIFAMGA IGLLGFVVWA HHMFTVGMDV DTRAYFTSAT
     MIIAVPTGIK VFSWLATMYG SKLTLSPPCL WAMGFVFLFT LGGLTGIVLS NSSIDITLHD
     TYYVVAHFHY VLSMGAVFAI MAGFIQWFPL FTGMSMNPLW LKIQFTTMFI GVNMTFFPQH
     FLGLAGMPRR YSDYPDMFTA WNIISSMGAI ISMVSMMMFI MIMWESLSSM RQTIFSSHMT
     SSLEWNHNLP PTEHTYNELP ILIKF
//