ID A0A060VEM3_KLEPN Unreviewed; 298 AA. AC A0A060VEM3; A0A0J2FNU8; A0A4V0H0I6; DT 03-SEP-2014, integrated into UniProtKB/TrEMBL. DT 03-SEP-2014, sequence version 1. DT 29-SEP-2021, entry version 70. DE RecName: Full=Tyrosine recombinase XerD {ECO:0000256|ARBA:ARBA00015810, ECO:0000256|HAMAP-Rule:MF_01807}; GN Name=xerD_1 {ECO:0000313|EMBL:SXN30647.1}; GN Synonyms=xerD {ECO:0000256|HAMAP-Rule:MF_01807, GN ECO:0000313|EMBL:AUY20800.1}, xerD_2 {ECO:0000313|EMBL:SQC22324.1}, GN xerD_3 {ECO:0000313|EMBL:STT81935.1}, xerD_4 GN {ECO:0000313|EMBL:STT06328.1}; GN ORFNames=B4U61_19045 {ECO:0000313|EMBL:TEA99473.1}, B5L96_14520 GN {ECO:0000313|EMBL:OVF70901.1}, BANRA_01662 GN {ECO:0000313|EMBL:VCW55188.1}, BANRA_03562 GN {ECO:0000313|EMBL:VCZ44708.1}, BANRA_04561 GN {ECO:0000313|EMBL:VCV63039.1}, BL124_00033500 GN {ECO:0000313|EMBL:ROG84450.1}, BS595_24370 GN {ECO:0000313|EMBL:ORZ66167.1}, BVX91_20715 GN {ECO:0000313|EMBL:PAX11544.1}, C3F39_19500 GN {ECO:0000313|EMBL:AUY20800.1}, DBX64_05375 GN {ECO:0000313|EMBL:QPA08950.1}, DD583_10645 GN {ECO:0000313|EMBL:RXZ11009.1}, DDJ63_11615 GN {ECO:0000313|EMBL:RFC25380.1}, DN601_06620 GN {ECO:0000313|EMBL:RWT64280.1}, DRB11_24560 GN {ECO:0000313|EMBL:RBN27076.1}, EHZ17_12455 GN {ECO:0000313|EMBL:NNP57849.1}, FXN67_05480 GN {ECO:0000313|EMBL:TYL81586.1}, G5637_06420 GN {ECO:0000313|EMBL:NGE18388.1}, G7Z27_04690 GN {ECO:0000313|EMBL:QLI07111.1}, GJJ08_004405 GN {ECO:0000313|EMBL:QOU52670.1}, GNG14_23710 GN {ECO:0000313|EMBL:MUD54923.1}, GTH21_18130 GN {ECO:0000313|EMBL:QIF86445.1}, NCTC11679_00882 GN {ECO:0000313|EMBL:STV33488.1}, NCTC13443_06275 GN {ECO:0000313|EMBL:STT06328.1}, NCTC13465_03909 GN {ECO:0000313|EMBL:SQC45359.1}, NCTC13635_02708 GN {ECO:0000313|EMBL:VEB02248.1}, NCTC204_03084 GN {ECO:0000313|EMBL:STV03030.1}, NCTC3279_03678 GN {ECO:0000313|EMBL:VTR52865.1}, NCTC5047_02873 GN {ECO:0000313|EMBL:STT81935.1}, NCTC5052_04183 GN {ECO:0000313|EMBL:STT95675.1}, NCTC5053_05258 GN {ECO:0000313|EMBL:STV51837.1}, NCTC8849_05245 GN {ECO:0000313|EMBL:STT56586.1}, NCTC9645_02901 GN {ECO:0000313|EMBL:SQC22324.1}, NCTC9661_01619 GN {ECO:0000313|EMBL:STU29063.1}, SAMEA24020668_01281 GN {ECO:0000313|EMBL:SSG76835.1}, SAMEA3499874_00840 GN {ECO:0000313|EMBL:SXG11045.1}, SAMEA3499901_01654 GN {ECO:0000313|EMBL:SXN30647.1}, SAMEA3512100_02307 GN {ECO:0000313|EMBL:SXU32816.1}, SAMEA3515130_02120 GN {ECO:0000313|EMBL:SYC59938.1}, SAMEA3538828_01629 GN {ECO:0000313|EMBL:SYR35506.1}, SAMEA3649466_02574 GN {ECO:0000313|EMBL:SVM85449.1}, SAMEA3649648_00132 GN {ECO:0000313|EMBL:SVK47462.1}, SAMEA3649758_00426 GN {ECO:0000313|EMBL:SVS89794.1}, SAMEA3720909_02519 GN {ECO:0000313|EMBL:SWF72294.1}, SAMEA3727643_03285 GN {ECO:0000313|EMBL:SWP81358.1}, SAMEA3727679_00425 GN {ECO:0000313|EMBL:SWR35885.1}, SAMEA3729663_02454 GN {ECO:0000313|EMBL:SWU95565.1}, SAMEA4364603_00912 GN {ECO:0000313|EMBL:SSK22593.1}; OS Klebsiella pneumoniae. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Klebsiella. OX NCBI_TaxID=573 {ECO:0000313|EMBL:SXN30647.1, ECO:0000313|Proteomes:UP000259975}; RN [1] {ECO:0000313|EMBL:ORZ66167.1, ECO:0000313|Proteomes:UP000193360} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MNCRE61 {ECO:0000313|EMBL:ORZ66167.1, RC ECO:0000313|Proteomes:UP000193360}; RA Johnson T.J., Hargreaves M., Snippes-Vignone P., Lynfield R.; RT "Comparison of KPC-2 positive Klebsiella pneumoniae."; RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:TEA99473.1, ECO:0000313|Proteomes:UP000297943} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MEC097 {ECO:0000313|EMBL:TEA99473.1, RC ECO:0000313|Proteomes:UP000297943}; RA Arya A.S.; RT "Isolation of Levoglucosan Utilizing Bacteria."; RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:OVF70901.1, ECO:0000313|Proteomes:UP000196447} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=39383 {ECO:0000313|EMBL:OVF70901.1, RC ECO:0000313|Proteomes:UP000196447}; RA Fouts D., Stalin M.J., Chen L., Wright M., Sutton G., Nguyen K., RA Vanduin D., Rojas L., Hujer A., Hujer K., Bonomo R., Kreiswirth B., RA Adams M.; RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|EMBL:PAX11544.1, ECO:0000313|Proteomes:UP000218240} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=WBB417 {ECO:0000313|EMBL:PAX11544.1, RC ECO:0000313|Proteomes:UP000218240}; RA Koh T.H., Abdul Rahman N., Teo J.W., La M.-V., Periaswamy B., Chen S.L.; RT "Draft Genome Sequence of a Singapore Klebsiella pneumoniae subsp. RT pnuemoniae isolate DS32358_14 Encoding the Carbapenemase Gene blaVIM-1."; RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases. RN [5] {ECO:0000313|Proteomes:UP000239813} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KPNIH48 {ECO:0000313|Proteomes:UP000239813}; RX PubMed=29437920; RG NISC Comparative Sequencing Program; RA Weingarten R.A., Johnson R.C., Conlan S., Ramsburg A.M., Dekker J.P., RA Lau A.F., Khil P., Odom R.T., Deming C., Park M., Thomas P.J., RA Henderson D.K., Palmore T.N., Segre J.A., Frank K.M.; RT "Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of RT Bacterial Plasmids Conferring Carbapenem Resistance."; RL MBio 9:e02011-e02017(2018). RN [6] {ECO:0000313|EMBL:AUY20800.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KPNIH48 {ECO:0000313|EMBL:AUY20800.1}; RA Weingarten R.A., Johnson R.C., Conlan S., Ramsburg A.M., Dekker J.P., RA Lau A.F., Khil P., Odom R.T., Deming C., Park M., Thomas P.J., RA Henderson D.K., Palmore T.N., Segre J.A., Frank K.M.; RT "Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of RT Bacterial Plasmids Conferring Carbapenem Resistance."; RL MBio 0:0-0(2018). RN [7] {ECO:0000313|EMBL:QPA08950.1, ECO:0000313|Proteomes:UP000593852} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=3214 {ECO:0000313|EMBL:QPA08950.1, RC ECO:0000313|Proteomes:UP000593852}; RA Liu B.-T., Su W.; RT "Characterization of Klebsiella pneumoniae strain."; RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases. RN [8] {ECO:0000313|EMBL:RFC25380.1, ECO:0000313|Proteomes:UP000256349} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=H1 {ECO:0000313|EMBL:RFC25380.1, RC ECO:0000313|Proteomes:UP000256349}; RA Khan F.A., Jass J., Soderquist B., Hellmark B., Ehricht R.; RT "Related carbapenemase-producing Klebsiella isolates detected in both a RT hospital and associated aquatic environment in Sweden."; RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases. RN [9] {ECO:0000313|EMBL:RXZ11009.1, ECO:0000313|Proteomes:UP000289252} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=775-DZ2-4B {ECO:0000313|EMBL:RXZ11009.1, RC ECO:0000313|Proteomes:UP000289252}; RA Zhang R., Li J., Wang Y., Shen J., Shen Z., Wang S.; RT "The molecular epidemiology of the NDM positive non-E. coli RT Enterobacteriaceae in poultry production environment."; RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases. RN [10] {ECO:0000313|EMBL:RWT64280.1, ECO:0000313|Proteomes:UP000288743} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=GEO_28_Up_A {ECO:0000313|EMBL:RWT64280.1, RC ECO:0000313|Proteomes:UP000288743}; RA Mathys D.A., Mollenkopf D.F., Feicht S.M., Adams R.J., Albers A.L., RA Grooters S.V., Stuever D.M., Daniels J.B., Wittum T.E.; RT "Carbapenemase-producing Enterobacteriaceae present in wastewater treatment RT plant effluent and nearby surface waters in the US."; RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases. RN [11] {ECO:0000313|EMBL:RBN27076.1, ECO:0000313|Proteomes:UP000252532} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JZX2124 {ECO:0000313|EMBL:RBN27076.1, RC ECO:0000313|Proteomes:UP000252532}; RA Sun Q., Gu D., Hu Y., Shu L., Hu J., Zhang R., Chen G.; RT "Colonization of different clones of blaKPC-2-bearing Klebsiella pneumoniae RT in the gastrointestinal tract."; RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases. RN [12] {ECO:0000313|Proteomes:UP000250675, ECO:0000313|Proteomes:UP000251721} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NCTC11679 {ECO:0000313|EMBL:STV33488.1, RC ECO:0000313|Proteomes:UP000255239}, NCTC13443 RC {ECO:0000313|EMBL:STT06328.1, ECO:0000313|Proteomes:UP000255518}, RC NCTC13465 {ECO:0000313|EMBL:SQC45359.1, RC ECO:0000313|Proteomes:UP000251721}, NCTC204 RC {ECO:0000313|EMBL:STV03030.1, ECO:0000313|Proteomes:UP000255192}, RC NCTC5047 {ECO:0000313|EMBL:STT81935.1, RC ECO:0000313|Proteomes:UP000254340}, NCTC5052 RC {ECO:0000313|EMBL:STT95675.1, ECO:0000313|Proteomes:UP000254103}, RC NCTC5053 {ECO:0000313|EMBL:STV51837.1, RC ECO:0000313|Proteomes:UP000254387}, NCTC8849 RC {ECO:0000313|EMBL:STT56586.1, ECO:0000313|Proteomes:UP000254799}, RC NCTC9645 {ECO:0000313|EMBL:SQC22324.1, RC ECO:0000313|Proteomes:UP000250675}, and NCTC9661 RC {ECO:0000313|EMBL:STU29063.1, ECO:0000313|Proteomes:UP000255137}; RG Pathogen Informatics; RA Doyle S.; RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases. RN [13] {ECO:0000313|Proteomes:UP000257327, ECO:0000313|Proteomes:UP000257587} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=4300STDY6470422 {ECO:0000313|EMBL:SSK22593.1, RC ECO:0000313|Proteomes:UP000252603}, 4300STDY6636983 RC {ECO:0000313|EMBL:SSG76835.1, ECO:0000313|Proteomes:UP000253526}, RC EuSCAPE_AT002 {ECO:0000313|EMBL:SXG11045.1, RC ECO:0000313|Proteomes:UP000257587}, EuSCAPE_AT029 RC {ECO:0000313|EMBL:SXN30647.1, ECO:0000313|Proteomes:UP000259975}, RC EuSCAPE_BE053 {ECO:0000313|EMBL:SWP81358.1, RC ECO:0000313|Proteomes:UP000259594}, EuSCAPE_BE092 RC {ECO:0000313|EMBL:SWR35885.1, ECO:0000313|Proteomes:UP000258785}, RC EuSCAPE_DE072 {ECO:0000313|EMBL:SXU32816.1, RC ECO:0000313|Proteomes:UP000259753}, EuSCAPE_ES150 RC {ECO:0000313|EMBL:SVM85449.1, ECO:0000313|Proteomes:UP000260067}, RC EuSCAPE_GR031 {ECO:0000313|EMBL:SVK47462.1, RC ECO:0000313|Proteomes:UP000258771}, EuSCAPE_GR139 RC {ECO:0000313|EMBL:SVS89794.1, ECO:0000313|Proteomes:UP000260499}, RC EuSCAPE_HU047 {ECO:0000313|EMBL:SYR35506.1, RC ECO:0000313|Proteomes:UP000258253}, EuSCAPE_IT101 RC {ECO:0000313|EMBL:SYC59938.1, ECO:0000313|Proteomes:UP000260197}, RC EuSCAPE_TR019 {ECO:0000313|EMBL:SWU95565.1, RC ECO:0000313|Proteomes:UP000257327}, EuSCAPE_UK014 RC {ECO:0000313|EMBL:SWF72294.1, ECO:0000313|Proteomes:UP000259364}, RC NCTC13635 {ECO:0000313|EMBL:VEB02248.1, RC ECO:0000313|Proteomes:UP000282433}, and NCTC3279 RC {ECO:0000313|EMBL:VTR52865.1, ECO:0000313|Proteomes:UP000395965}; RG Pathogen Informatics; RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases. RN [14] {ECO:0000313|Proteomes:UP000269373, ECO:0000313|Proteomes:UP000276935} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Kpneu003 {ECO:0000313|EMBL:VCV63039.1}, Kpneu014 RC {ECO:0000313|EMBL:VCW55188.1}, and Kpneu037 RC {ECO:0000313|EMBL:VCZ44708.1}; RA Noll B N.; RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases. RN [15] {ECO:0000313|EMBL:ROG84450.1, ECO:0000313|Proteomes:UP000283322} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CRK0165 {ECO:0000313|EMBL:ROG84450.1, RC ECO:0000313|Proteomes:UP000283322}; RA Vanduin D., Fouts D., Wright M., Sutton G., Nguyen K., Kreiswirth B., RA Chen L., Rojas L., Hujer A., Hujer K., Bonomo R., Adams M.; RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases. RN [16] {ECO:0000313|EMBL:TYL81586.1, ECO:0000313|Proteomes:UP000322977} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=UCO-494 {ECO:0000313|EMBL:TYL81586.1, RC ECO:0000313|Proteomes:UP000322977}; RA Morales-Leon F., Caro C., Opazo-Capurro A., Lincopan N., RA Dominguez-Yevenes M., Lima C., Bello-Toledo H., Gonzalez-Rocha G.; RT "Phenotypic and genetic characterization of extended-spectrum b-lactamase- RT producing hypermucoviscous Klebsiella pneumoniae from Chile."; RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases. RN [17] {ECO:0000313|EMBL:MUD54923.1, ECO:0000313|Proteomes:UP000488995} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KP_10042 {ECO:0000313|EMBL:MUD54923.1, RC ECO:0000313|Proteomes:UP000488995}; RA Zhou K.; RT "Emergence of a novel subclone of carbapenem-resistant Klebsiella RT pneumoniae ST11 with enhanced virulence and transmissibility: a molecular RT epidemiological, clinical, genomic study."; RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases. RN [18] {ECO:0000313|Proteomes:UP000556239} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KP-MO-27 {ECO:0000313|Proteomes:UP000556239}; RA Gentile B., Grottola A., Orlando G., Fregni Serpini G., Venturelli C., RA Meschiari M., Anselmo A., Fillo S., Fortunato A., Lista F., Pecorari M., RA Mussini C.; RT "A retrospective whole-genome sequencing analysis of carbapenem- and RT colistin-resistant Klebsiella pneumoniae nosocomial strains isolated during RT an MDR surveillance program."; RL Antibiotics (Basel) 9:246-240(2020). RN [19] {ECO:0000313|EMBL:QOU52670.1, ECO:0000313|Proteomes:UP000439817} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CriePir120 {ECO:0000313|EMBL:QOU52670.1, RC ECO:0000313|Proteomes:UP000439817}; RX PubMed=32429555; RA Shelenkov A., Mikhaylova Y., Yanushevich Y., Samoilov A., Petrova L., RA Fomina V., Gusarov V., Zamyatin M., Shagin D., Akimkin V.; RT "Molecular Typing, Characterization of Antimicrobial Resistance, Virulence RT Profiling and Analysis of Whole-Genome Sequence of Clinical Klebsiella RT pneumoniae Isolates."; RL Antibiotics (Basel) 9:0-E261(2020). RN [20] {ECO:0000313|EMBL:QIF86445.1, ECO:0000313|Proteomes:UP000502019} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=2019036D {ECO:0000313|EMBL:QIF86445.1, RC ECO:0000313|Proteomes:UP000502019}; RA Peng K.; RT "Characterization of a poultry multidrug resistance Klebsiella pneumoniae RT strain harboring mcr-8.2."; RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases. RN [21] {ECO:0000313|EMBL:NGE18388.1, ECO:0000313|Proteomes:UP000474962} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KPM_60 {ECO:0000313|EMBL:NGE18388.1, RC ECO:0000313|Proteomes:UP000474962}; RA Tokajian S., El Chaar M., El Khoury M.; RT "WGS of Carbapenem-Resistant Entrobacteriaceae."; RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases. RN [22] {ECO:0000313|EMBL:QLI07111.1, ECO:0000313|Proteomes:UP000509467} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=11KM256 {ECO:0000313|EMBL:QLI07111.1, RC ECO:0000313|Proteomes:UP000509467}; RA Brilhante M., Perreten V.; RT "Whole genome sequencing of global problem clones of OXA-48-producing RT Klebsiella pneumoniae from the veterinary setting in Switzerland."; RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases. RN [23] {ECO:0000313|EMBL:NNP57849.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=KP-MO-27 {ECO:0000313|EMBL:NNP57849.1}; RA Gentile B., Grottola A., Orlando G., Fregni Serpini G., Venturelli C., RA Meschiari M., Anselmo A., Fillo S., Fortunato A., Lista F., Pecorari M., RA Mussini C.; RT "A retrospective whole-genome sequencing analysis of carbapenem- and RT colistin-resistant Klebsiella pneumoniae nosocomial strains isolated during RT an MDR surveillance program."; RL Antibiotics (Basel) 9:0-0(0). CC -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing CC the cutting and rejoining of the recombining DNA molecules. Binds CC cooperatively to specific DNA consensus sequences that are separated CC from XerC binding sites by a short central region, forming the CC heterotetrameric XerC-XerD complex that recombines DNA substrates. The CC complex is essential to convert dimers of the bacterial chromosome into CC monomers to permit their segregation at cell division. It also CC contributes to the segregational stability of plasmids. In the complex CC XerD specifically exchanges the bottom DNA strands. {ECO:0000256|HAMAP- CC Rule:MF_01807}. CC -!- ACTIVITY REGULATION: FtsK may regulate the catalytic switch between CC XerC and XerD in the heterotetrameric complex during the two steps of CC the recombination process. {ECO:0000256|HAMAP-Rule:MF_01807}. CC -!- SUBUNIT: Forms a cyclic heterotetrameric complex composed of two CC molecules of XerC and two molecules of XerD, in which XerC interacts CC with XerD via its C-terminal region, XerD interacts with XerC via its CC C-terminal region and so on. {ECO:0000256|ARBA:ARBA00011483, CC ECO:0000256|HAMAP-Rule:MF_01807}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, CC ECO:0000256|HAMAP-Rule:MF_01807}. CC -!- SIMILARITY: Belongs to the 'phage' integrase family. XerD subfamily. CC {ECO:0000256|ARBA:ARBA00010450, ECO:0000256|HAMAP-Rule:MF_01807}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP026392; AUY20800.1; -; Genomic_DNA. DR EMBL; WNSY01000029; MUD54923.1; -; Genomic_DNA. DR EMBL; JAAJRV010000003; NGE18388.1; -; Genomic_DNA. DR EMBL; RQIX01000009; NNP57849.1; -; Genomic_DNA. DR EMBL; MSLG01000059; ORZ66167.1; -; Genomic_DNA. DR EMBL; NDBK01000064; OVF70901.1; -; Genomic_DNA. DR EMBL; NSMB01000014; PAX11544.1; -; Genomic_DNA. DR EMBL; CP047336; QIF86445.1; -; Genomic_DNA. DR EMBL; CP049716; QLI07111.1; -; Genomic_DNA. DR EMBL; CP063008; QOU52670.1; -; Genomic_DNA. DR EMBL; CP028850; QPA08950.1; -; Genomic_DNA. DR EMBL; QMKE01000026; RBN27076.1; -; Genomic_DNA. DR EMBL; QDDZ01000007; RFC25380.1; -; Genomic_DNA. DR EMBL; MPYG04000255; ROG84450.1; -; Genomic_DNA. DR EMBL; QKPF01000003; RWT64280.1; -; Genomic_DNA. DR EMBL; QFMF01000008; RXZ11009.1; -; Genomic_DNA. DR EMBL; UASO01000004; SQC22324.1; -; Genomic_DNA. DR EMBL; UAWQ01000018; SQC45359.1; -; Genomic_DNA. DR EMBL; UFBV01000002; SSG76835.1; -; Genomic_DNA. DR EMBL; UFEU01000002; SSK22593.1; -; Genomic_DNA. DR EMBL; UGKT01000001; STT06328.1; -; Genomic_DNA. DR EMBL; UGLC01000002; STT56586.1; -; Genomic_DNA. DR EMBL; UGLH01000006; STT81935.1; -; Genomic_DNA. DR EMBL; UGLJ01000002; STT95675.1; -; Genomic_DNA. DR EMBL; UGLQ01000003; STU29063.1; -; Genomic_DNA. DR EMBL; UGMD01000002; STV03030.1; -; Genomic_DNA. DR EMBL; UGMG01000001; STV33488.1; -; Genomic_DNA. DR EMBL; UGMN01000004; STV51837.1; -; Genomic_DNA. DR EMBL; UIRT01000001; SVK47462.1; -; Genomic_DNA. DR EMBL; UITM01000007; SVM85449.1; -; Genomic_DNA. DR EMBL; UIYA01000001; SVS89794.1; -; Genomic_DNA. DR EMBL; UJHH01000010; SWF72294.1; -; Genomic_DNA. DR EMBL; UJOV01000011; SWP81358.1; -; Genomic_DNA. DR EMBL; UJPY01000001; SWR35885.1; -; Genomic_DNA. DR EMBL; UJSO01000008; SWU95565.1; -; Genomic_DNA. DR EMBL; UKAW01000002; SXG11045.1; -; Genomic_DNA. DR EMBL; UKGE01000006; SXN30647.1; -; Genomic_DNA. DR EMBL; UKLK01000004; SXU32816.1; -; Genomic_DNA. DR EMBL; UKRN01000004; SYC59938.1; -; Genomic_DNA. DR EMBL; ULCI01000006; SYR35506.1; -; Genomic_DNA. DR EMBL; MWQX01000029; TEA99473.1; -; Genomic_DNA. DR EMBL; VSSY01000003; TYL81586.1; -; Genomic_DNA. DR EMBL; UWVD01000001; VCV63039.1; -; Genomic_DNA. DR EMBL; UWVV01000001; VCW55188.1; -; Genomic_DNA. DR EMBL; UWXT01000001; VCZ44708.1; -; Genomic_DNA. DR EMBL; LR134162; VEB02248.1; -; Genomic_DNA. DR EMBL; CABEFC010000003; VTR52865.1; -; Genomic_DNA. DR RefSeq; WP_004144729.1; NZ_WWEY01000150.1. DR EnsemblBacteria; AIT00307; AIT00307; PMK1_00810. DR EnsemblBacteria; AUY20800; AUY20800; C3F39_19500. DR EnsemblBacteria; AVB70589; AVB70589; C3483_04075. DR EnsemblBacteria; KLY12001; KLY12001; SK89_04359. DR EnsemblBacteria; OON35129; OON35129; BU230_34595. DR EnsemblBacteria; PAX11544; PAX11544; BVX91_20715. DR EnsemblBacteria; PPK23654; PPK23654; CSC88_13350. DR EnsemblBacteria; PWF56157; PWF56157; C7V41_27010. DR EnsemblBacteria; RCJ95709; RCJ95709; DM059_25510. DR EnsemblBacteria; RDT68825; RDT68825; DXF97_06455. DR EnsemblBacteria; SBX92074; SBX92074; SAMEA3531848_02889. DR EnsemblBacteria; SQC22324; SQC22324; NCTC9645_02901. DR EnsemblBacteria; SQC45359; SQC45359; NCTC13465_03909. DR EnsemblBacteria; SSF57305; SSF57305; SAMEA23986918_01179. DR EnsemblBacteria; SSF86199; SSF86199; SAMEA24002668_05251. DR EnsemblBacteria; SSK22593; SSK22593; SAMEA4364603_00912. DR EnsemblBacteria; STT06328; STT06328; NCTC13443_06275. DR EnsemblBacteria; STT56586; STT56586; NCTC8849_05245. DR EnsemblBacteria; STT68740; STT68740; NCTC1936_04966. DR EnsemblBacteria; STT81935; STT81935; NCTC5047_02873. DR EnsemblBacteria; STT95675; STT95675; NCTC5052_04183. DR EnsemblBacteria; STU29063; STU29063; NCTC9661_01619. DR EnsemblBacteria; STV03030; STV03030; NCTC204_03084. DR EnsemblBacteria; STV33488; STV33488; NCTC11679_00882. DR EnsemblBacteria; STV51837; STV51837; NCTC5053_05258. DR EnsemblBacteria; SVJ39266; SVJ39266; SAMEA4394730_02526. DR EnsemblBacteria; VEB02248; VEB02248; NCTC13635_02708. DR GeneID; 64293635; -. DR KEGG; kpb:FH42_12590; -. DR KEGG; kpne:KU54_004475; -. DR KEGG; kpnu:LI86_04480; -. DR KEGG; kpx:PMK1_00810; -. DR OrthoDB; 745068at2; -. DR Proteomes; UP000193360; Unassembled WGS sequence. DR Proteomes; UP000196447; Unassembled WGS sequence. DR Proteomes; UP000218240; Unassembled WGS sequence. DR Proteomes; UP000239813; Chromosome. DR Proteomes; UP000250675; Unassembled WGS sequence. DR Proteomes; UP000251721; Unassembled WGS sequence. DR Proteomes; UP000252532; Unassembled WGS sequence. DR Proteomes; UP000252603; Unassembled WGS sequence. DR Proteomes; UP000253526; Unassembled WGS sequence. DR Proteomes; UP000254103; Unassembled WGS sequence. DR Proteomes; UP000254340; Unassembled WGS sequence. DR Proteomes; UP000254387; Unassembled WGS sequence. DR Proteomes; UP000254799; Unassembled WGS sequence. DR Proteomes; UP000255137; Unassembled WGS sequence. DR Proteomes; UP000255192; Unassembled WGS sequence. DR Proteomes; UP000255239; Unassembled WGS sequence. DR Proteomes; UP000255518; Unassembled WGS sequence. DR Proteomes; UP000256349; Unassembled WGS sequence. DR Proteomes; UP000257327; Unassembled WGS sequence. DR Proteomes; UP000257587; Unassembled WGS sequence. DR Proteomes; UP000258253; Unassembled WGS sequence. DR Proteomes; UP000258771; Unassembled WGS sequence. DR Proteomes; UP000258785; Unassembled WGS sequence. DR Proteomes; UP000259364; Unassembled WGS sequence. DR Proteomes; UP000259594; Unassembled WGS sequence. DR Proteomes; UP000259753; Unassembled WGS sequence. DR Proteomes; UP000259975; Unassembled WGS sequence. DR Proteomes; UP000260067; Unassembled WGS sequence. DR Proteomes; UP000260197; Unassembled WGS sequence. DR Proteomes; UP000260499; Unassembled WGS sequence. DR Proteomes; UP000269373; Unassembled WGS sequence. DR Proteomes; UP000276935; Unassembled WGS sequence. DR Proteomes; UP000277476; Unassembled WGS sequence. DR Proteomes; UP000282433; Chromosome 1. DR Proteomes; UP000283322; Unassembled WGS sequence. DR Proteomes; UP000288743; Unassembled WGS sequence. DR Proteomes; UP000289252; Unassembled WGS sequence. DR Proteomes; UP000297943; Unassembled WGS sequence. DR Proteomes; UP000322977; Unassembled WGS sequence. DR Proteomes; UP000395965; Unassembled WGS sequence. DR Proteomes; UP000439817; Chromosome. DR Proteomes; UP000474962; Unassembled WGS sequence. DR Proteomes; UP000488995; Unassembled WGS sequence. DR Proteomes; UP000502019; Chromosome. DR Proteomes; UP000509467; Chromosome. DR Proteomes; UP000556239; Unassembled WGS sequence. DR Proteomes; UP000593852; Chromosome. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0009037; F:tyrosine-based site-specific recombinase activity; IEA:UniProtKB-UniRule. DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW. DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW. DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule. DR GO; GO:0006313; P:transposition, DNA-mediated; IEA:UniProtKB-UniRule. DR Gene3D; 1.10.150.130; -; 1. DR Gene3D; 1.10.443.10; -; 1. DR HAMAP; MF_01808; Recomb_XerC_XerD; 1. DR HAMAP; MF_01807; Recomb_XerD; 1. DR InterPro; IPR044068; CB. DR InterPro; IPR011010; DNA_brk_join_enz. DR InterPro; IPR013762; Integrase-like_cat_sf. DR InterPro; IPR002104; Integrase_catalytic. DR InterPro; IPR010998; Integrase_recombinase_N. DR InterPro; IPR004107; Integrase_SAM-like_N. DR InterPro; IPR011932; Recomb_XerD. DR InterPro; IPR023009; Tyrosine_recombinase_XerC/XerD. DR Pfam; PF02899; Phage_int_SAM_1; 1. DR Pfam; PF00589; Phage_integrase; 1. DR SUPFAM; SSF56349; SSF56349; 1. DR TIGRFAMs; TIGR02225; recomb_XerD; 1. DR PROSITE; PS51900; CB; 1. DR PROSITE; PS51898; TYR_RECOMBINASE; 1. PE 3: Inferred from homology; KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP- KW Rule:MF_01807}; KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP- KW Rule:MF_01807}; KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829, ECO:0000256|HAMAP- KW Rule:MF_01807}; KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01807}; KW DNA integration {ECO:0000256|ARBA:ARBA00022908, ECO:0000256|HAMAP- KW Rule:MF_01807}; KW DNA recombination {ECO:0000256|ARBA:ARBA00023172, ECO:0000256|HAMAP- KW Rule:MF_01807}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP- KW Rule:MF_01807}. FT DOMAIN 2..87 FT /note="Core-binding (CB)" FT /evidence="ECO:0000259|PROSITE:PS51900" FT DOMAIN 108..292 FT /note="Tyr recombinase" FT /evidence="ECO:0000259|PROSITE:PS51898" FT ACT_SITE 148 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" FT ACT_SITE 172 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" FT ACT_SITE 244 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" FT ACT_SITE 247 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" FT ACT_SITE 270 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" FT ACT_SITE 279 FT /note="O-(3'-phospho-DNA)-tyrosine intermediate" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" SQ SEQUENCE 298 AA; 33967 MW; DF893A2E8C2D2B88 CRC64; MKQDLALIEQ FLDALWLERN LAENTLSAYR RDLTMLVEWL HHRGLSLASV GSDDLQALLA ERQSGGYKAT STARLLSAVR RFFQHLYREK IRPDDPSALL ASPKLPQRLP KDLSEAQVER LLQAPLVEQP LELRDKAMLE VLYATGLRVS ELVGLTMSDI SLRQGVLRVV GKGNKERLVP LGEEAVLWVE NYLEYGRPWL LNGVASDVLF PSQRAQQMTR QTFWHRIKHY AVLAGIDSEK LSPHVLRHAF ATHLLNHGAD LRVVQMLLGH SDLSTTQIYT HVATERLRQL HQQHHPRA //