ID A0A060VEM3_KLEPN Unreviewed; 298 AA. AC A0A060VEM3; A0A0J2FNU8; A0A4V0H0I6; DT 03-SEP-2014, integrated into UniProtKB/TrEMBL. DT 03-SEP-2014, sequence version 1. DT 02-DEC-2020, entry version 66. DE RecName: Full=Tyrosine recombinase XerD {ECO:0000256|ARBA:ARBA00015810, ECO:0000256|HAMAP-Rule:MF_01807}; GN Name=xerD_1 {ECO:0000313|EMBL:CAA1277204.1}; GN Synonyms=xerD {ECO:0000256|HAMAP-Rule:MF_01807, GN ECO:0000313|EMBL:AUU96018.1}, xerD_2 {ECO:0000313|EMBL:SQC22324.1}, GN xerD_3 {ECO:0000313|EMBL:STT81935.1}, xerD_4 GN {ECO:0000313|EMBL:STT06328.1}; GN ORFNames=B6R99_15785 {ECO:0000313|EMBL:OXS98679.1}, BANRA_01662 GN {ECO:0000313|EMBL:VCW55188.1}, BANRA_03562 GN {ECO:0000313|EMBL:VCZ44708.1}, BL124_00033500 GN {ECO:0000313|EMBL:ROG84450.1}, BVX91_20715 GN {ECO:0000313|EMBL:PAX11544.1}, C2U49_15015 GN {ECO:0000313|EMBL:AUU96018.1}, C3F39_19500 GN {ECO:0000313|EMBL:AUY20800.1}, C4Y50_001360 GN {ECO:0000313|EMBL:ROG94080.1}, C7V41_27010 GN {ECO:0000313|EMBL:PWF56157.1}, C8P71_4754 GN {ECO:0000313|EMBL:RMB23049.1}, CK508_011550 GN {ECO:0000313|EMBL:RJS99761.1}, DD581_26750 GN {ECO:0000313|EMBL:RXY83143.1}, DD583_10645 GN {ECO:0000313|EMBL:RXZ11009.1}, DM059_25510 GN {ECO:0000313|EMBL:RCJ95709.1}, DM060_24430 GN {ECO:0000313|EMBL:RCJ90806.1}, DM078_02370 GN {ECO:0000313|EMBL:RBZ26255.1}, EAO17_09240 GN {ECO:0000313|EMBL:RRF06376.1}, EPB11_26880 GN {ECO:0000313|EMBL:QHQ45820.1}, EXT45_09365 GN {ECO:0000313|EMBL:RZG38655.1}, F0330_09235 GN {ECO:0000313|EMBL:KAA0486132.1}, F1D54_20785 GN {ECO:0000313|EMBL:KAA1498412.1}, F3G17_18980 GN {ECO:0000313|EMBL:KAA5741288.1}, F3G25_11040 GN {ECO:0000313|EMBL:KAA5735152.1}, FAT93_01500 GN {ECO:0000313|EMBL:THS93593.1}, FCH06_019205 GN {ECO:0000313|EMBL:TYY80925.1}, FKC87_22590 GN {ECO:0000313|EMBL:TQC87086.1}, FXN60_05960 GN {ECO:0000313|EMBL:QEI34884.1}, FXN67_05480 GN {ECO:0000313|EMBL:TYL81586.1}, G5637_06420 GN {ECO:0000313|EMBL:NGE18388.1}, GF489_04285 GN {ECO:0000313|EMBL:MRD85777.1}, GJJ01_23895 GN {ECO:0000313|EMBL:MRJ98980.1}, GS419_04655 GN {ECO:0000313|EMBL:QHD73497.1}, GZH28_20120 GN {ECO:0000313|EMBL:NER57043.1}, NCTC11679_00882 GN {ECO:0000313|EMBL:STV33488.1}, NCTC13443_06275 GN {ECO:0000313|EMBL:STT06328.1}, NCTC13465_03909 GN {ECO:0000313|EMBL:SQC45359.1}, NCTC13635_02708 GN {ECO:0000313|EMBL:VEB02248.1}, NCTC1936_04966 GN {ECO:0000313|EMBL:STT68740.1}, NCTC204_03084 GN {ECO:0000313|EMBL:STV03030.1}, NCTC5047_02873 GN {ECO:0000313|EMBL:STT81935.1}, NCTC5052_04183 GN {ECO:0000313|EMBL:STT95675.1}, NCTC5053_05258 GN {ECO:0000313|EMBL:STV51837.1}, NCTC8849_05245 GN {ECO:0000313|EMBL:STT56586.1}, NCTC9645_02901 GN {ECO:0000313|EMBL:SQC22324.1}, NCTC9661_01619 GN {ECO:0000313|EMBL:STU29063.1}, SAMEA104567806_02957 GN {ECO:0000313|EMBL:VGD10272.1}, SAMEA104567834_01863 GN {ECO:0000313|EMBL:VGE27219.1}, SAMEA104567846_02785 GN {ECO:0000313|EMBL:VGF18314.1}, SAMEA104567853_04838 GN {ECO:0000313|EMBL:VGF91089.1}, SAMEA104567857_04294 GN {ECO:0000313|EMBL:VGG04295.1}, SAMEA104567906_02271 GN {ECO:0000313|EMBL:VFZ30775.1}, SAMEA104567925_01220 GN {ECO:0000313|EMBL:VGB58175.1}, SAMEA1712987_01233 GN {ECO:0000313|EMBL:VAP03302.1}, SAMEA24002668_05251 GN {ECO:0000313|EMBL:SSF86199.1}, SAMEA3531867_02661 GN {ECO:0000313|EMBL:VTT41013.1}, SAMEA3538702_03118 GN {ECO:0000313|EMBL:SYM14167.1}, SAMEA3649466_02574 GN {ECO:0000313|EMBL:SVM85449.1}, SAMEA3649709_00426 GN {ECO:0000313|EMBL:SVT03116.1}, SAMEA3649772_01001 GN {ECO:0000313|EMBL:VUK54045.1}, SAMEA3673122_01102 GN {ECO:0000313|EMBL:SWE21563.1}, SAMEA3673128_04663 GN {ECO:0000313|EMBL:SWE82846.1}, SAMEA3727630_03240 GN {ECO:0000313|EMBL:SWP37910.1}, SAMEA3729660_00746 GN {ECO:0000313|EMBL:SWU32708.1}, SAMEA3729780_00830 GN {ECO:0000313|EMBL:CAA1277204.1}, SAMEA4364603_00912 GN {ECO:0000313|EMBL:SSK22593.1}, SAMEA4873570_04906 GN {ECO:0000313|EMBL:VGH84727.1}, SAMEA4873575_01525 GN {ECO:0000313|EMBL:VGH91921.1}, SAMEA4873581_02632 GN {ECO:0000313|EMBL:VGI38069.1}, SAMEA4873632_04892 GN {ECO:0000313|EMBL:VGL14206.1}, SAMEA4873640_04643 GN {ECO:0000313|EMBL:VGL46693.1}, SK89_04359 GN {ECO:0000313|EMBL:KLY12001.1}; OS Klebsiella pneumoniae. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; OC Enterobacteriaceae; Klebsiella. OX NCBI_TaxID=573 {ECO:0000313|EMBL:KLY12001.1}; RN [1] {ECO:0000313|EMBL:KLY12001.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CHS153 {ECO:0000313|EMBL:KLY12001.1}; RG The Broad Institute Genomics Platform; RG The Broad Institute Genome Sequencing Center for Infectious Disease; RA Earl A.M., Onderdonk A.B., Kirby J., Ferraro M.J., Huang S., Spencer M., RA Fodor A., Hooper D., Dekker J., O'Brien T., Quan V., Gombosev A., RA Delaney M., DuBois A., Ernst C., Kim D.S., Rossman W., Gohs F., Petruso H., RA Nozar T., Mougeot F., Manson-McGuire A., Young S., Abouelleil A., Cao P., RA Chapman S.B., Griggs A., Priest M., Shea T., Wortman I., Wortman J.R., RA Nusbaum C., Birren B.; RT "The Genome Sequence of None."; RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:OXS98679.1, ECO:0000313|Proteomes:UP000215430} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=VD412 {ECO:0000313|EMBL:OXS98679.1, RC ECO:0000313|Proteomes:UP000215430}; RA Tran L.D.; RT "Vietnam strains VN412."; RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:PAX11544.1, ECO:0000313|Proteomes:UP000218240} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=WBB417 {ECO:0000313|EMBL:PAX11544.1, RC ECO:0000313|Proteomes:UP000218240}; RA Koh T.H., Abdul Rahman N., Teo J.W., La M.-V., Periaswamy B., Chen S.L.; RT "Draft Genome Sequence of a Singapore Klebsiella pneumoniae subsp. RT pnuemoniae isolate DS32358_14 Encoding the Carbapenemase Gene blaVIM-1."; RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|EMBL:RRF06376.1, ECO:0000313|Proteomes:UP000275975} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KLPN_104 {ECO:0000313|EMBL:RRF06376.1, RC ECO:0000313|Proteomes:UP000275975}; RX PubMed=30373801; RA Tamma P.D., Fan Y., Bergman Y., Pertea G., Kazmi A., Lewis S., RA Carroll K.C., Schatz M.C., Timp W., Simner P.J.; RT "Applying Rapid Whole Genome Sequencing to Predict Phenotypic Antimicrobial RT Susceptibility Testing Results Among Carbapenem-Resistant Klebsiella RT pneumoniae Clinical Isolates."; RL Antimicrob. Agents Chemother. 0:0-0(2018). RN [5] {ECO:0000313|Proteomes:UP000236255, ECO:0000313|Proteomes:UP000239813} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KPNIH48 {ECO:0000313|Proteomes:UP000239813}, and KPNIH49 RC {ECO:0000313|Proteomes:UP000236255}; RX PubMed=29437920; RG NISC Comparative Sequencing Program; RA Weingarten R.A., Johnson R.C., Conlan S., Ramsburg A.M., Dekker J.P., RA Lau A.F., Khil P., Odom R.T., Deming C., Park M., Thomas P.J., RA Henderson D.K., Palmore T.N., Segre J.A., Frank K.M.; RT "Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of RT Bacterial Plasmids Conferring Carbapenem Resistance."; RL MBio 9:e02011-17(2018). RN [6] {ECO:0000313|EMBL:AUY20800.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KPNIH48 {ECO:0000313|EMBL:AUY20800.1}; RA Weingarten R.A., Johnson R.C., Conlan S., Ramsburg A.M., Dekker J.P., RA Lau A.F., Khil P., Odom R.T., Deming C., Park M., Thomas P.J., RA Henderson D.K., Palmore T.N., Segre J.A., Frank K.M.; RT "Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of RT Bacterial Plasmids Conferring Carbapenem Resistance."; RL MBio 0:0-0(2018). RN [7] {ECO:0000313|EMBL:AUU96018.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=KPNIH49 {ECO:0000313|EMBL:AUU96018.1}; RG NISC Comparative Sequencing Program; RA Weingarten R.A., Johnson R.C., Conlan S., Ramsburg A.M., Dekker J.P., RA Lau A.F., Khil P., Odom R.T., Deming C., Park M., Thomas P.J., RA Henderson D.K., Palmore T.N., Segre J.A., Frank K.M.; RT "Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of RT Bacterial Plasmids Conferring Carbapenem Resistance."; RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases. RN [8] {ECO:0000313|EMBL:AUU96018.1, ECO:0000313|Proteomes:UP000236255} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KPNIH49 {ECO:0000313|EMBL:AUU96018.1, RC ECO:0000313|Proteomes:UP000236255}; RA Segre J.A., Mullikin J.; RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases. RN [9] {ECO:0000313|EMBL:PWF56157.1, ECO:0000313|Proteomes:UP000245017} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KPL0.2 {ECO:0000313|EMBL:PWF56157.1, RC ECO:0000313|Proteomes:UP000245017}; RA Le Guern R., Grandjean T., Bauduin M., Loquet A., Faure K., Kipnis E., RA Dessein R.; RT "A murine model of gut colonization with Klebsiella pneumoniae NDM."; RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases. RN [10] {ECO:0000313|EMBL:RXY83143.1, ECO:0000313|Proteomes:UP000289252, ECO:0000313|Proteomes:UP000290276} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=3DZ2-3B {ECO:0000313|EMBL:RXY83143.1, RC ECO:0000313|Proteomes:UP000290276}, and 775-DZ2-4B RC {ECO:0000313|EMBL:RXZ11009.1, ECO:0000313|Proteomes:UP000289252}; RA Zhang R., Li J., Wang Y., Shen J., Shen Z., Wang S.; RT "The molecular epidemiology of the NDM positive non-E. coli RT Enterobacteriaceae in poultry production environment."; RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases. RN [11] {ECO:0000313|Proteomes:UP000250675, ECO:0000313|Proteomes:UP000251721, ECO:0000313|Proteomes:UP000254103} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NCTC11679 {ECO:0000313|EMBL:STV33488.1, RC ECO:0000313|Proteomes:UP000255239}, NCTC13443 RC {ECO:0000313|EMBL:STT06328.1, ECO:0000313|Proteomes:UP000255518}, RC NCTC13465 {ECO:0000313|EMBL:SQC45359.1, RC ECO:0000313|Proteomes:UP000251721}, NCTC1936 RC {ECO:0000313|EMBL:STT68740.1, ECO:0000313|Proteomes:UP000254753}, RC NCTC204 {ECO:0000313|EMBL:STV03030.1, RC ECO:0000313|Proteomes:UP000255192}, NCTC5047 RC {ECO:0000313|EMBL:STT81935.1, ECO:0000313|Proteomes:UP000254340}, RC NCTC5052 {ECO:0000313|EMBL:STT95675.1, RC ECO:0000313|Proteomes:UP000254103}, NCTC5053 RC {ECO:0000313|EMBL:STV51837.1, ECO:0000313|Proteomes:UP000254387}, RC NCTC8849 {ECO:0000313|EMBL:STT56586.1, RC ECO:0000313|Proteomes:UP000254799}, NCTC9645 RC {ECO:0000313|EMBL:SQC22324.1, ECO:0000313|Proteomes:UP000250675}, and RC NCTC9661 {ECO:0000313|EMBL:STU29063.1, RC ECO:0000313|Proteomes:UP000255137}; RG Pathogen Informatics; RA Doyle S.; RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases. RN [12] {ECO:0000313|Proteomes:UP000252755, ECO:0000313|Proteomes:UP000253217, ECO:0000313|Proteomes:UP000253559} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BC-4224 {ECO:0000313|EMBL:RCJ90806.1, RC ECO:0000313|Proteomes:UP000252755}, BC_4223 RC {ECO:0000313|EMBL:RCJ95709.1, ECO:0000313|Proteomes:UP000253217}, and RC BC_5001 {ECO:0000313|EMBL:RBZ26255.1, RC ECO:0000313|Proteomes:UP000253559}; RA Martins R.C.R., Perdigao-Neto L.V., Costa S.F., Levin A.S.S.; RT "Klebsiella pneumoniae genome sequencing and assembly."; RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases. RN [13] {ECO:0000313|EMBL:RBZ26255.1, ECO:0000313|Proteomes:UP000252755, ECO:0000313|Proteomes:UP000253559} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BC-4224 {ECO:0000313|EMBL:RCJ90806.1, RC ECO:0000313|Proteomes:UP000252755}, and BC_5001 RC {ECO:0000313|EMBL:RBZ26255.1, ECO:0000313|Proteomes:UP000253559}; RA Martins R.C., Perdigao-Neto L.V., Costa S.F., Levin A.S.S.; RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases. RN [14] {ECO:0000313|EMBL:SSF86199.1, ECO:0000313|Proteomes:UP000252603, ECO:0000313|Proteomes:UP000253632} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=2485STDY5438277 {ECO:0000313|EMBL:VAP03302.1, RC ECO:0000313|Proteomes:UP000326261}, 3754STDY6292969 RC {ECO:0000313|EMBL:CAA1277204.1, ECO:0000313|Proteomes:UP000257626}, RC 4300STDY6470422 {ECO:0000313|EMBL:SSK22593.1, RC ECO:0000313|Proteomes:UP000252603}, 4300STDY6636959 RC {ECO:0000313|EMBL:SSF86199.1, ECO:0000313|Proteomes:UP000253632}, RC 5012STDY7312591 {ECO:0000313|EMBL:VGD10272.1, RC ECO:0000313|Proteomes:UP000295363}, 5012STDY7312619 RC {ECO:0000313|EMBL:VGE27219.1}, 5012STDY7312664 RC {ECO:0000313|EMBL:VGF18314.1, ECO:0000313|Proteomes:UP000337947}, RC 5012STDY7312671 {ECO:0000313|EMBL:VGF91089.1, RC ECO:0000313|Proteomes:UP000381540}, 5012STDY7312675 RC {ECO:0000313|EMBL:VGG04295.1}, 5012STDY7312724 RC {ECO:0000313|EMBL:VFZ30775.1, ECO:0000313|Proteomes:UP000406376}, RC 5012STDY7312743 {ECO:0000313|EMBL:VGB58175.1, RC ECO:0000313|Proteomes:UP000386678}, 5012STDY7626369 RC {ECO:0000313|EMBL:VGH84727.1, ECO:0000313|Proteomes:UP000343310}, RC 5012STDY7626374 {ECO:0000313|EMBL:VGH91921.1, RC ECO:0000313|Proteomes:UP000360885}, 5012STDY7626380 RC {ECO:0000313|EMBL:VGI38069.1, ECO:0000313|Proteomes:UP000390008}, RC 5012STDY7626430 {ECO:0000313|EMBL:VGL14206.1, RC ECO:0000313|Proteomes:UP000376235}, 5012STDY7626438 RC {ECO:0000313|EMBL:VGL46693.1}, EuSCAPE_BE040 RC {ECO:0000313|EMBL:SWP37910.1, ECO:0000313|Proteomes:UP000258702}, RC EuSCAPE_ES150 {ECO:0000313|EMBL:SVM85449.1, RC ECO:0000313|Proteomes:UP000260067}, EuSCAPE_GR090 RC {ECO:0000313|EMBL:SVT03116.1, ECO:0000313|Proteomes:UP000259889}, RC EuSCAPE_GR153 {ECO:0000313|EMBL:VUK54045.1, RC ECO:0000313|Proteomes:UP000443666}, EuSCAPE_IT334 RC {ECO:0000313|EMBL:SYM14167.1, ECO:0000313|Proteomes:UP000260565}, RC EuSCAPE_RO021 {ECO:0000313|EMBL:SWE21563.1, RC ECO:0000313|Proteomes:UP000257792}, EuSCAPE_RO027 RC {ECO:0000313|EMBL:SWE82846.1, ECO:0000313|Proteomes:UP000258129}, RC EuSCAPE_TR130 {ECO:0000313|EMBL:SWU32708.1, RC ECO:0000313|Proteomes:UP000258699}, F1-8-ERB4 RC {ECO:0000313|EMBL:VTT41013.1}, and NCTC13635 RC {ECO:0000313|EMBL:VEB02248.1, ECO:0000313|Proteomes:UP000282433}; RG Pathogen Informatics; RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases. RN [15] {ECO:0000313|EMBL:RCJ95709.1, ECO:0000313|Proteomes:UP000253217} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=BC_4223 {ECO:0000313|EMBL:RCJ95709.1, RC ECO:0000313|Proteomes:UP000253217}; RA Quirk P.G., Krulwich T.A.; RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases. RN [16] {ECO:0000313|EMBL:RJS99761.1, ECO:0000313|Proteomes:UP000218552} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=B35 {ECO:0000313|EMBL:RJS99761.1, RC ECO:0000313|Proteomes:UP000218552}; RA Araujo B.F., Campos P.A., Royer S., Ferreira M.L., Goncalves I.R., RA Batistao D.W.F., Cerdeira L.T., Brito C.S., Gontijo-Filho P., Ribas R.M.; RT "Klebsiella pneumoniae KPC-2-producing B35 strain."; RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases. RN [17] {ECO:0000313|EMBL:RMB23049.1, ECO:0000313|Proteomes:UP000271388} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JE01 {ECO:0000313|EMBL:RMB23049.1, RC ECO:0000313|Proteomes:UP000271388}; RA Guss A.; RT "PacBio sequencing to determine microbial DNA methylation."; RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases. RN [18] {ECO:0000313|EMBL:VCW55188.1, ECO:0000313|Proteomes:UP000269373, ECO:0000313|Proteomes:UP000277476} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Kpneu014 {ECO:0000313|EMBL:VCW55188.1}, and Kpneu037 RC {ECO:0000313|EMBL:VCZ44708.1}; RA Noll B N.; RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases. RN [19] {ECO:0000313|EMBL:ROG94080.1, ECO:0000313|Proteomes:UP000286610} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CRK0390 {ECO:0000313|EMBL:ROG94080.1, RC ECO:0000313|Proteomes:UP000286610}; RA Vanduin D., Fouts D., Sutton G., Nguyen K., Hujer A., Hujer K., Bonomo R.; RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases. RN [20] {ECO:0000313|EMBL:ROG84450.1, ECO:0000313|Proteomes:UP000283322} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CRK0165 {ECO:0000313|EMBL:ROG84450.1, RC ECO:0000313|Proteomes:UP000283322}; RA Vanduin D., Fouts D., Wright M., Sutton G., Nguyen K., Kreiswirth B., RA Chen L., Rojas L., Hujer A., Hujer K., Bonomo R., Adams M.; RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases. RN [21] {ECO:0000313|EMBL:QEI34884.1, ECO:0000313|Proteomes:UP000322548} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KLP268 {ECO:0000313|EMBL:QEI34884.1, RC ECO:0000313|Proteomes:UP000322548}; RA Marsh J.W., Shields R.K.; RT "Evolution of Outbreak-Causing Carbapenem-Resistant Klebsiella pneumoniae RT ST258 at a Tertiary Care Hospital over 8 Years."; RL MBio 0:0-0(2019). RN [22] {ECO:0000313|EMBL:MRD85777.1, ECO:0000313|Proteomes:UP000475774} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=99 {ECO:0000313|EMBL:MRD85777.1, RC ECO:0000313|Proteomes:UP000475774}; RA Paraschiv S., Surleac M., Czobor Barbu I., Popa L.I., Gheorghe I., RA Otelea D., Chifiriuc M.C.; RT "Whole genome sequencing snapshot of multi-drug resistant Klebsiella RT pneumoniae strains from hospitals and receiving wastewater treatment plants RT in Southern Romania."; RL PLoS ONE 0:0-0(2019). RN [23] {ECO:0000313|EMBL:RZG38655.1, ECO:0000313|Proteomes:UP000293472} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=53 {ECO:0000313|EMBL:RZG38655.1, RC ECO:0000313|Proteomes:UP000293472}; RA Newire E., Aydin A., Juma S., Enne V., Roberts A.P.; RT "Identification of a Type IV CRISPR-Cas system located exclusively on RT IncHI1B/ IncFIB plasmids in Enterobacteriaceae."; RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases. RN [24] {ECO:0000313|EMBL:THS93593.1, ECO:0000313|Proteomes:UP000305572} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SIKP198 {ECO:0000313|EMBL:THS93593.1, RC ECO:0000313|Proteomes:UP000305572}; RA Fouts D., Sutton G., Singh I., Nguyen K.; RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases. RN [25] {ECO:0000313|EMBL:TQC87086.1, ECO:0000313|Proteomes:UP000316663} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=T38-P35-mcr3-tc {ECO:0000313|EMBL:TQC87086.1, RC ECO:0000313|Proteomes:UP000316663}; RA Yu Y.; RT "An mcr-1 and mcr-3 co-harboring Klebsiella pneumoniae strain from human in RT Thailand."; RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases. RN [26] {ECO:0000313|EMBL:KAA0486132.1, ECO:0000313|Proteomes:UP000323019} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=K7 {ECO:0000313|EMBL:KAA0486132.1, RC ECO:0000313|Proteomes:UP000323019}; RA Cho G.-S., Stein M., Fiedler G., Igbinosa E.O., Heuermann L., Brinks E., RA Neve H., Franz C.M.A.P.; RT "Characterization of antibiotic-resistant enterobacteria."; RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases. RN [27] {ECO:0000313|EMBL:TYY80925.1, ECO:0000313|Proteomes:UP000323143} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=AS001328 {ECO:0000313|EMBL:TYY80925.1, RC ECO:0000313|Proteomes:UP000323143}; RA Beisken S.; RT "Evaluating DNBSEQ for clinical isolate sequencing and identification of RT antibiotic resistance."; RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases. RN [28] {ECO:0000313|EMBL:TYL81586.1, ECO:0000313|Proteomes:UP000322977} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=UCO-494 {ECO:0000313|EMBL:TYL81586.1, RC ECO:0000313|Proteomes:UP000322977}; RA Morales-Leon F., Caro C., Opazo-Capurro A., Lincopan N., RA Dominguez-Yevenes M., Lima C., Bello-Toledo H., Gonzalez-Rocha G.; RT "Phenotypic and genetic characterization of extended-spectrum b-lactamase- RT producing hypermucoviscous Klebsiella pneumoniae from Chile."; RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases. RN [29] {ECO:0000313|Proteomes:UP000322675, ECO:0000313|Proteomes:UP000322831} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=P12 {ECO:0000313|Proteomes:UP000322675}, and P23 RC {ECO:0000313|Proteomes:UP000322831}; RA Zhang X.; RT "Genome of bacteria."; RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases. RN [30] {ECO:0000313|EMBL:KAA1498412.1, ECO:0000313|Proteomes:UP000322821} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=195D9 {ECO:0000313|EMBL:KAA1498412.1, RC ECO:0000313|Proteomes:UP000322821}; RA Bonnin R.A., Jousset A.B., Chiarelli A., Emeraud C., Glaser P., Naas T., RA Dortet L.; RT "Unexpected genetic diversity among KPC-producing Klebsiella in France."; RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases. RN [31] {ECO:0000313|EMBL:KAA5735152.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=P12 {ECO:0000313|EMBL:KAA5741288.1}, and P23 RC {ECO:0000313|EMBL:KAA5735152.1}; RA Zhang X.; RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases. RN [32] {ECO:0000313|EMBL:QHQ45820.1, ECO:0000313|Proteomes:UP000465088} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MRK9 {ECO:0000313|EMBL:QHQ45820.1, RC ECO:0000313|Proteomes:UP000465088}; RA Azam M., Gaind R., Yadav G., Singh R.; RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases. RN [33] {ECO:0000313|EMBL:MRJ98980.1, ECO:0000313|Proteomes:UP000441029} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CriePir226 {ECO:0000313|EMBL:MRJ98980.1, RC ECO:0000313|Proteomes:UP000441029}; RA Shelenkov A., Mikhaylova Y., Yanushevich Y., Samoilov A., Petrova L., RA Fomina V., Gusarov V., Zamyatin M., Shagin D.; RT "Molecular typing, antibiotic resistance determination and virulence RT profiling for 36 multidrug-resistant clinical Klebsiella pneumoniae RT isolates using second- and third-generation sequencing."; RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases. RN [34] {ECO:0000313|EMBL:QHD73497.1, ECO:0000313|Proteomes:UP000464108} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Kp36 {ECO:0000313|EMBL:QHD73497.1, RC ECO:0000313|Proteomes:UP000464108}; RA Tan D.; RT "Mobile Genetic Element-Mediated Frameshifting in wcaJ Provides Phage RT Resistance in Klebsiella pneumoniae."; RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases. RN [35] {ECO:0000313|EMBL:NER57043.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=UCO505 {ECO:0000313|EMBL:NER57043.1}; RA Morales-Leon F., Opazo-Capurro A., Gonzalez-Rocha G., Bello-Toledo H.; RT "Colistin-heteroresistance in extended-spectrum -lactamase producing RT Klebsiella pneumoniae from Chile."; RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases. RN [36] {ECO:0000313|EMBL:NGE18388.1, ECO:0000313|Proteomes:UP000474962} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KPM_60 {ECO:0000313|EMBL:NGE18388.1, RC ECO:0000313|Proteomes:UP000474962}; RA Tokajian S., El Chaar M., El Khoury M.; RT "WGS of Carbapenem-Resistant Entrobacteriaceae."; RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing CC the cutting and rejoining of the recombining DNA molecules. Binds CC cooperatively to specific DNA consensus sequences that are separated CC from XerC binding sites by a short central region, forming the CC heterotetrameric XerC-XerD complex that recombines DNA substrates. The CC complex is essential to convert dimers of the bacterial chromosome into CC monomers to permit their segregation at cell division. It also CC contributes to the segregational stability of plasmids. In the complex CC XerD specifically exchanges the bottom DNA strands. {ECO:0000256|HAMAP- CC Rule:MF_01807}. CC -!- ACTIVITY REGULATION: FtsK may regulate the catalytic switch between CC XerC and XerD in the heterotetrameric complex during the two steps of CC the recombination process. {ECO:0000256|HAMAP-Rule:MF_01807}. CC -!- SUBUNIT: Forms a cyclic heterotetrameric complex composed of two CC molecules of XerC and two molecules of XerD, in which XerC interacts CC with XerD via its C-terminal region, XerD interacts with XerC via its CC C-terminal region and so on. {ECO:0000256|ARBA:ARBA00011483, CC ECO:0000256|HAMAP-Rule:MF_01807}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, CC ECO:0000256|HAMAP-Rule:MF_01807}. CC -!- SIMILARITY: Belongs to the 'phage' integrase family. XerD subfamily. CC {ECO:0000256|ARBA:ARBA00010450, ECO:0000256|HAMAP-Rule:MF_01807}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP026178; AUU96018.1; -; Genomic_DNA. DR EMBL; CP026392; AUY20800.1; -; Genomic_DNA. DR EMBL; UJWM02000001; CAA1277204.1; -; Genomic_DNA. DR EMBL; VTUL01000007; KAA0486132.1; -; Genomic_DNA. DR EMBL; VUBL01000034; KAA1498412.1; -; Genomic_DNA. DR EMBL; VWRA01000009; KAA5735152.1; -; Genomic_DNA. DR EMBL; VWRE01000015; KAA5741288.1; -; Genomic_DNA. DR EMBL; LEUQ01000014; KLY12001.1; -; Genomic_DNA. DR EMBL; WJBQ01000002; MRD85777.1; -; Genomic_DNA. DR EMBL; WJVL01000023; MRJ98980.1; -; Genomic_DNA. DR EMBL; JAAFZD010000025; NER57043.1; -; Genomic_DNA. DR EMBL; JAAJRV010000003; NGE18388.1; -; Genomic_DNA. DR EMBL; NBIK01000013; OXS98679.1; -; Genomic_DNA. DR EMBL; NSMB01000014; PAX11544.1; -; Genomic_DNA. DR EMBL; PYBH01000031; PWF56157.1; -; Genomic_DNA. DR EMBL; CP043047; QEI34884.1; -; Genomic_DNA. DR EMBL; CP047192; QHD73497.1; -; Genomic_DNA. DR EMBL; CP043859; QHQ45820.1; -; Genomic_DNA. DR EMBL; QOHW01000001; RBZ26255.1; -; Genomic_DNA. DR EMBL; QOUF01000707; RCJ90806.1; -; Genomic_DNA. DR EMBL; QOUG01001467; RCJ95709.1; -; Genomic_DNA. DR EMBL; NTHY02000039; RJS99761.1; -; Genomic_DNA. DR EMBL; REFB01000001; RMB23049.1; -; Genomic_DNA. DR EMBL; MPYG04000255; ROG84450.1; -; Genomic_DNA. DR EMBL; PTFF02000005; ROG94080.1; -; Genomic_DNA. DR EMBL; RDAM01000001; RRF06376.1; -; Genomic_DNA. DR EMBL; QFMH01000384; RXY83143.1; -; Genomic_DNA. DR EMBL; QFMF01000008; RXZ11009.1; -; Genomic_DNA. DR EMBL; SGOL01000007; RZG38655.1; -; Genomic_DNA. DR EMBL; UASO01000004; SQC22324.1; -; Genomic_DNA. DR EMBL; UAWQ01000018; SQC45359.1; -; Genomic_DNA. DR EMBL; UFBE01000027; SSF86199.1; -; Genomic_DNA. DR EMBL; UFEU01000002; SSK22593.1; -; Genomic_DNA. DR EMBL; UGKT01000001; STT06328.1; -; Genomic_DNA. DR EMBL; UGLC01000002; STT56586.1; -; Genomic_DNA. DR EMBL; UGLI01000001; STT68740.1; -; Genomic_DNA. DR EMBL; UGLH01000006; STT81935.1; -; Genomic_DNA. DR EMBL; UGLJ01000002; STT95675.1; -; Genomic_DNA. DR EMBL; UGLQ01000003; STU29063.1; -; Genomic_DNA. DR EMBL; UGMD01000002; STV03030.1; -; Genomic_DNA. DR EMBL; UGMG01000001; STV33488.1; -; Genomic_DNA. DR EMBL; UGMN01000004; STV51837.1; -; Genomic_DNA. DR EMBL; UITM01000007; SVM85449.1; -; Genomic_DNA. DR EMBL; UIYB01000001; SVT03116.1; -; Genomic_DNA. DR EMBL; UJGH01000002; SWE21563.1; -; Genomic_DNA. DR EMBL; UJGS01000028; SWE82846.1; -; Genomic_DNA. DR EMBL; UJOM01000005; SWP37910.1; -; Genomic_DNA. DR EMBL; UJRJ01000002; SWU32708.1; -; Genomic_DNA. DR EMBL; UKYO01000011; SYM14167.1; -; Genomic_DNA. DR EMBL; STEC01000002; THS93593.1; -; Genomic_DNA. DR EMBL; VIAJ01000020; TQC87086.1; -; Genomic_DNA. DR EMBL; VSSY01000003; TYL81586.1; -; Genomic_DNA. DR EMBL; SUOY02000023; TYY80925.1; -; Genomic_DNA. DR EMBL; UNZU01000004; VAP03302.1; -; Genomic_DNA. DR EMBL; UWVV01000001; VCW55188.1; -; Genomic_DNA. DR EMBL; UWXT01000001; VCZ44708.1; -; Genomic_DNA. DR EMBL; LR134162; VEB02248.1; -; Genomic_DNA. DR EMBL; CAAGTI010000002; VFZ30775.1; -; Genomic_DNA. DR EMBL; CAAGVF010000002; VGB58175.1; -; Genomic_DNA. DR EMBL; CAAGWD010000010; VGD10272.1; -; Genomic_DNA. DR EMBL; CAAGXF010000002; VGE27219.1; -; Genomic_DNA. DR EMBL; CAAGXU010000002; VGF18314.1; -; Genomic_DNA. DR EMBL; CAAGXW010000031; VGF91089.1; -; Genomic_DNA. DR EMBL; CAAGYG010000012; VGG04295.1; -; Genomic_DNA. DR EMBL; CAAGZQ010000024; VGH84727.1; -; Genomic_DNA. DR EMBL; CAAGZV010000002; VGH91921.1; -; Genomic_DNA. DR EMBL; CAAHAF010000004; VGI38069.1; -; Genomic_DNA. DR EMBL; CAAHCC010000014; VGL14206.1; -; Genomic_DNA. DR EMBL; CAAHCJ010000024; VGL46693.1; -; Genomic_DNA. DR EMBL; FLXF02000002; VTT41013.1; -; Genomic_DNA. DR EMBL; CABGAI010000001; VUK54045.1; -; Genomic_DNA. DR RefSeq; WP_004144729.1; NZ_WYAM01000011.1. DR EnsemblBacteria; AIT00307; AIT00307; PMK1_00810. DR EnsemblBacteria; ALR26130; ALR26130; AGG09_18445. DR EnsemblBacteria; KSY13972; KSY13972; APT98_23625. DR EnsemblBacteria; SBX92074; SBX92074; SAMEA3531848_02889. DR EnsemblBacteria; SBY65672; SBY65672; SAMEA3531778_02882. DR GeneID; 46803126; -. DR KEGG; kpb:FH42_12590; -. DR KEGG; kpne:KU54_004475; -. DR KEGG; kpnu:LI86_04480; -. DR KEGG; kpx:PMK1_00810; -. DR PATRIC; fig|571.67.peg.4504; -. DR OrthoDB; 745068at2; -. DR Proteomes; UP000215430; Unassembled WGS sequence. DR Proteomes; UP000218240; Unassembled WGS sequence. DR Proteomes; UP000218552; Unassembled WGS sequence. DR Proteomes; UP000236255; Chromosome. DR Proteomes; UP000239813; Chromosome. DR Proteomes; UP000245017; Unassembled WGS sequence. DR Proteomes; UP000250675; Unassembled WGS sequence. DR Proteomes; UP000251721; Unassembled WGS sequence. DR Proteomes; UP000252603; Unassembled WGS sequence. DR Proteomes; UP000252755; Unassembled WGS sequence. DR Proteomes; UP000253217; Unassembled WGS sequence. DR Proteomes; UP000253559; Unassembled WGS sequence. DR Proteomes; UP000253632; Unassembled WGS sequence. DR Proteomes; UP000254103; Unassembled WGS sequence. DR Proteomes; UP000254340; Unassembled WGS sequence. DR Proteomes; UP000254387; Unassembled WGS sequence. DR Proteomes; UP000254753; Unassembled WGS sequence. DR Proteomes; UP000254799; Unassembled WGS sequence. DR Proteomes; UP000255137; Unassembled WGS sequence. DR Proteomes; UP000255192; Unassembled WGS sequence. DR Proteomes; UP000255239; Unassembled WGS sequence. DR Proteomes; UP000255518; Unassembled WGS sequence. DR Proteomes; UP000257626; Unassembled WGS sequence. DR Proteomes; UP000257792; Unassembled WGS sequence. DR Proteomes; UP000258129; Unassembled WGS sequence. DR Proteomes; UP000258699; Unassembled WGS sequence. DR Proteomes; UP000258702; Unassembled WGS sequence. DR Proteomes; UP000259889; Unassembled WGS sequence. DR Proteomes; UP000260067; Unassembled WGS sequence. DR Proteomes; UP000260565; Unassembled WGS sequence. DR Proteomes; UP000269373; Unassembled WGS sequence. DR Proteomes; UP000271388; Unassembled WGS sequence. DR Proteomes; UP000275975; Unassembled WGS sequence. DR Proteomes; UP000277476; Unassembled WGS sequence. DR Proteomes; UP000282433; Chromosome 1. DR Proteomes; UP000283322; Unassembled WGS sequence. DR Proteomes; UP000286610; Unassembled WGS sequence. DR Proteomes; UP000289252; Unassembled WGS sequence. DR Proteomes; UP000290276; Unassembled WGS sequence. DR Proteomes; UP000293472; Unassembled WGS sequence. DR Proteomes; UP000295363; Unassembled WGS sequence. DR Proteomes; UP000305572; Unassembled WGS sequence. DR Proteomes; UP000316663; Unassembled WGS sequence. DR Proteomes; UP000322548; Chromosome. DR Proteomes; UP000322675; Unassembled WGS sequence. DR Proteomes; UP000322821; Unassembled WGS sequence. DR Proteomes; UP000322831; Unassembled WGS sequence. DR Proteomes; UP000322977; Unassembled WGS sequence. DR Proteomes; UP000323019; Unassembled WGS sequence. DR Proteomes; UP000323143; Unassembled WGS sequence. DR Proteomes; UP000326261; Unassembled WGS sequence. DR Proteomes; UP000337947; Unassembled WGS sequence. DR Proteomes; UP000343310; Unassembled WGS sequence. DR Proteomes; UP000360885; Unassembled WGS sequence. DR Proteomes; UP000376235; Unassembled WGS sequence. DR Proteomes; UP000381540; Unassembled WGS sequence. DR Proteomes; UP000386678; Unassembled WGS sequence. DR Proteomes; UP000390008; Unassembled WGS sequence. DR Proteomes; UP000406376; Unassembled WGS sequence. DR Proteomes; UP000441029; Unassembled WGS sequence. DR Proteomes; UP000443666; Unassembled WGS sequence. DR Proteomes; UP000464108; Chromosome. DR Proteomes; UP000465088; Chromosome. DR Proteomes; UP000474962; Unassembled WGS sequence. DR Proteomes; UP000475774; Unassembled WGS sequence. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0009037; F:tyrosine-based site-specific recombinase activity; IEA:UniProtKB-UniRule. DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW. DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW. DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule. DR GO; GO:0006313; P:transposition, DNA-mediated; IEA:UniProtKB-UniRule. DR Gene3D; 1.10.150.130; -; 1. DR Gene3D; 1.10.443.10; -; 1. DR HAMAP; MF_01808; Recomb_XerC_XerD; 1. DR HAMAP; MF_01807; Recomb_XerD; 1. DR InterPro; IPR044068; CB. DR InterPro; IPR011010; DNA_brk_join_enz. DR InterPro; IPR013762; Integrase-like_cat_sf. DR InterPro; IPR002104; Integrase_catalytic. DR InterPro; IPR010998; Integrase_recombinase_N. DR InterPro; IPR004107; Integrase_SAM-like_N. DR InterPro; IPR011932; Recomb_XerD. DR InterPro; IPR023009; Tyrosine_recombinase_XerC/XerD. DR Pfam; PF02899; Phage_int_SAM_1; 1. DR Pfam; PF00589; Phage_integrase; 1. DR SUPFAM; SSF56349; SSF56349; 1. DR TIGRFAMs; TIGR02225; recomb_XerD; 1. DR PROSITE; PS51900; CB; 1. DR PROSITE; PS51898; TYR_RECOMBINASE; 1. PE 3: Inferred from homology; KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP- KW Rule:MF_01807}; KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP- KW Rule:MF_01807}; KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829, ECO:0000256|HAMAP- KW Rule:MF_01807}; KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01807}; KW DNA integration {ECO:0000256|ARBA:ARBA00022908, ECO:0000256|HAMAP- KW Rule:MF_01807}; KW DNA recombination {ECO:0000256|ARBA:ARBA00023172, ECO:0000256|HAMAP- KW Rule:MF_01807}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP- KW Rule:MF_01807, ECO:0000256|PROSITE-ProRule:PRU01248}. FT DOMAIN 2..87 FT /note="Core-binding (CB)" FT /evidence="ECO:0000259|PROSITE:PS51900" FT DOMAIN 108..292 FT /note="Tyr recombinase" FT /evidence="ECO:0000259|PROSITE:PS51898" FT ACT_SITE 148 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" FT ACT_SITE 172 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" FT ACT_SITE 244 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" FT ACT_SITE 247 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" FT ACT_SITE 270 FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" FT ACT_SITE 279 FT /note="O-(3'-phospho-DNA)-tyrosine intermediate" FT /evidence="ECO:0000256|HAMAP-Rule:MF_01807" SQ SEQUENCE 298 AA; 33967 MW; DF893A2E8C2D2B88 CRC64; MKQDLALIEQ FLDALWLERN LAENTLSAYR RDLTMLVEWL HHRGLSLASV GSDDLQALLA ERQSGGYKAT STARLLSAVR RFFQHLYREK IRPDDPSALL ASPKLPQRLP KDLSEAQVER LLQAPLVEQP LELRDKAMLE VLYATGLRVS ELVGLTMSDI SLRQGVLRVV GKGNKERLVP LGEEAVLWVE NYLEYGRPWL LNGVASDVLF PSQRAQQMTR QTFWHRIKHY AVLAGIDSEK LSPHVLRHAF ATHLLNHGAD LRVVQMLLGH SDLSTTQIYT HVATERLRQL HQQHHPRA //