ID A0A031JGU5_SPHPI Unreviewed; 158 AA. AC A0A031JGU5; DT 09-JUL-2014, integrated into UniProtKB/TrEMBL. DT 09-JUL-2014, sequence version 1. DT 07-JAN-2015, entry version 6. DE RecName: Full=Transcription elongation factor GreA {ECO:0000256|HAMAP-Rule:MF_00105, ECO:0000256|SAAS:SAAS00033968}; DE AltName: Full=Transcript cleavage factor GreA {ECO:0000256|HAMAP-Rule:MF_00105}; GN Name=greA {ECO:0000256|HAMAP-Rule:MF_00105, GN ECO:0000313|EMBL:EZP72503.1}; GN ORFNames=BV96_01943 {ECO:0000313|EMBL:EZP72503.1}; OS Sphingomonas paucimobilis (Pseudomonas paucimobilis). OC Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales; OC Sphingomonadaceae; Sphingomonas. OX NCBI_TaxID=13689 {ECO:0000313|EMBL:EZP72503.1}; RN [1] {ECO:0000313|EMBL:EZP72503.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=EPA505 {ECO:0000313|EMBL:EZP72503.1}; RA Gan H.M., Gan H.Y., Chew T.H., Savka M.A.; RT "Whole genome sequence of Sphingomonas paucimobilis EPA 505."; RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Necessary for efficient RNA polymerase transcription CC elongation past template-encoded arresting sites. The arresting CC sites in DNA have the property of trapping a certain fraction of CC elongating RNA polymerases that pass through, resulting in locked CC ternary complexes. Cleavage of the nascent transcript by cleavage CC factors such as GreA or GreB allows the resumption of elongation CC from the new 3'terminus. GreA releases sequences of 2 to 3 CC nucleotides. {ECO:0000256|HAMAP-Rule:MF_00105, CC ECO:0000256|RuleBase:RU000556, ECO:0000256|SAAS:SAAS00078390}. CC -!- SIMILARITY: Belongs to the GreA/GreB family. {ECO:0000256|HAMAP- CC Rule:MF_00105, ECO:0000256|RuleBase:RU000556}. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. {ECO:0000313|EMBL:EZP72503.1}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; JFYY01000007; EZP72503.1; -; Genomic_DNA. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro. DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW. DR Gene3D; 1.10.287.180; -; 1. DR Gene3D; 3.10.50.30; -; 1. DR HAMAP; MF_00105; GreA_GreB; 1. DR InterPro; IPR018151; TF_GreA/GreB_CS. DR InterPro; IPR006359; Tscrpt_elong_fac_GreA. DR InterPro; IPR028624; Tscrpt_elong_fac_GreA/B. DR InterPro; IPR001437; Tscrpt_elong_fac_GreA/B_C. DR InterPro; IPR023459; Tscrpt_elong_fac_GreA/B_fam. DR InterPro; IPR022691; Tscrpt_elong_fac_GreA/B_N. DR Pfam; PF01272; GreA_GreB; 1. DR Pfam; PF03449; GreA_GreB_N; 1. DR PIRSF; PIRSF006092; GreA_GreB; 1. DR SUPFAM; SSF46557; SSF46557; 1. DR TIGRFAMs; TIGR01462; greA; 1. DR PROSITE; PS00830; GREAB_2; 1. PE 3: Inferred from homology; KW Coiled coil {ECO:0000256|HAMAP-Rule:MF_00105}; KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_00105, KW ECO:0000256|RuleBase:RU000556}; KW Transcription {ECO:0000256|HAMAP-Rule:MF_00105, KW ECO:0000256|RuleBase:RU000556}; KW Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00105, KW ECO:0000256|RuleBase:RU000556}. FT COILED 5 76 {ECO:0000256|HAMAP-Rule:MF_00105}. SQ SEQUENCE 158 AA; 17302 MW; 3D14BA7ECD1D1B82 CRC64; MATVEKMPML QAGYDKLTAQ LRELKAERPL IVDAIEEARA HGDLSENAEY HAAKERQGQV EATIADLEDK LSRAQIIDPA TLSGDKVIFG ATVTLLDEDD KPVKYQIVGQ AEADAKLGMI SYNSPLGRAL IGRQVGEEVE VSVPSGDKFY LVDKIEFI //