ID A0A023PRX2_CARAO Unreviewed; 219 AA. AC A0A023PRX2; DT 09-JUL-2014, integrated into UniProtKB/TrEMBL. DT 09-JUL-2014, sequence version 1. DT 03-SEP-2014, entry version 2. DE RecName: Full=Cytochrome c oxidase subunit 1; DE EC=1.9.3.1; DE Flags: Fragment; GN Name=COI; OS Carabus auronitens auronitens. OG Mitochondrion. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Coleoptera; Adephaga; Caraboidea; OC Carabidae; Carabinae; Carabini; Carabina; Carabus; Chrysocarabus. OX NCBI_TaxID=1149200; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=24497030; DOI=10.1093/molbev/msu063; RA Cruaud A., Gautier M., Galan M., Foucaud J., Saune L., Genson G., RA Dubois E., Nidelet S., Deuve T., Rasplus J.Y.; RT "Empirical Assessment of RAD Sequencing for Interspecific Phylogeny."; RL Mol. Biol. Evol. 31:1272-1274(2014). CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. CO I is the CC catalytic subunit of the enzyme. Electrons originating in CC cytochrome c are transferred via the copper A center of subunit 2 CC and heme A of subunit 1 to the bimetallic center formed by heme A3 CC and copper B (By similarity). CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4 CC ferricytochrome c + 2 H(2)O. CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KJ158787; AHX37007.1; -; Genomic_DNA. PE 3: Inferred from homology; KW Copper; Electron transport; Heme; Iron; Membrane; Metal-binding; KW Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; KW Respiratory chain; Transmembrane; Transport. FT NON_TER 1 1 FT NON_TER 219 219 SQ SEQUENCE 219 AA; 23541 MW; 611E8E1A03D49EC0 CRC64; TLYFIFGAWS GMVGTSLSML IRAELGNPGS LIGDDQIYNV IVTAHAFVMI FFMVMPIMIG GFGNWLVPLM LGAPDMAFPR MNNMSFWLLP PSLTLLLMSS MVEKGAGTGW TVYPPLSSGI AHSGASVDLA IFSLHLAGVS SILGAVNFIT TIINMRSVGM TFDRMPLFVW SVGITALLLL LSLPVLAGAI TMLLTDRNLN TSFFDPAGGG DPILYQHLF //