ID A0A023J5Z3_MOUSE Unreviewed; 176 AA. AC A0A023J5Z3; DT 09-JUL-2014, integrated into UniProtKB/TrEMBL. DT 09-JUL-2014, sequence version 1. DT 11-MAY-2016, entry version 7. DE RecName: Full=NADH-ubiquinone oxidoreductase chain 6 {ECO:0000256|RuleBase:RU004430}; DE EC=1.6.5.3 {ECO:0000256|RuleBase:RU004430}; GN Name=ND6 {ECO:0000313|EMBL:AHG32160.1}; OS Mus musculus musculus (eastern European house mouse). OG Mitochondrion {ECO:0000313|EMBL:AHG32160.1}. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=39442 {ECO:0000313|EMBL:AHG32160.1}; RN [1] {ECO:0000313|EMBL:AHG32160.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=UQ {ECO:0000313|EMBL:AHG32160.1}; RA Xu J., Huang L., Jing M.; RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: NADH + ubiquinone + 5 H(+)(In) = NAD(+) + CC ubiquinol + 4 H(+)(Out). {ECO:0000256|RuleBase:RU004430}. CC -!- SIMILARITY: Belongs to the complex I subunit 6 family. CC {ECO:0000256|RuleBase:RU004429, ECO:0000256|SAAS:SAAS00585382}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; KF781654; AHG32160.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC. DR InterPro; IPR001457; NADH_UbQ/plastoQ_OxRdtase_su6. DR Pfam; PF00499; Oxidored_q3; 1. PE 3: Inferred from homology; KW Membrane {ECO:0000256|SAAS:SAAS00477717, ECO:0000256|SAM:Phobius}; KW Mitochondrion {ECO:0000256|RuleBase:RU004430, KW ECO:0000313|EMBL:AHG32160.1}; NAD {ECO:0000256|SAAS:SAAS00477704}; KW Oxidoreductase {ECO:0000256|RuleBase:RU004429, KW ECO:0000256|SAAS:SAAS00477695}; Signal {ECO:0000256|SAM:SignalP}; KW Transmembrane {ECO:0000256|SAAS:SAAS00477711, KW ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00477687, KW ECO:0000256|SAM:Phobius}. FT SIGNAL 1 18 {ECO:0000256|SAM:SignalP}. FT CHAIN 19 176 NADH-ubiquinone oxidoreductase chain 6. FT {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5001522996. FT TRANSMEM 36 66 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 86 106 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 142 167 Helical. {ECO:0000256|SAM:Phobius}. SQ SEQUENCE 176 AA; 19103 MW; 92BEAD0D6ECC232E CRC64; MNNYIFVLSS LFLVGCLGLA LKPSPIYGGL GLIVSGFVGC LMVLGFGGSF LGLMVFLIYL GGMLVVFGYT TAMATEEYPE TWGSNWLILG FLVLGVIMEV FLIYALNYYD EVGVINLDGL GDWLMYEVDD VGVMLEGGIG VAAMYSCATW MMVVAGWSLF AGIFIIIEIT RNNLSM //