{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A160JN66","uniProtkbId":"A0A160JN66_PHYDU","entryAudit":{"firstPublicDate":"2016-07-06","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2016-07-06","entryVersion":22,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Phylloglossum drummondii","commonName":"Pigmy clubmoss","synonyms":["Huperzia drummondii"],"taxonId":70003,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ANC96972.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Lycopodiopsida","Lycopodiales","Lycopodiaceae","Huperzioideae","Phylloglossum"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"non-specific serine/threonine protein kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"2.7.11.1"}]},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ANC96972.1"}],"value":"PHOT"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047899"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009903"}],"value":"Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":117,"modifier":"EXACT"},"end":{"value":405,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Active site","location":{"start":{"value":242,"modifier":"EXACT"},"end":{"value":242,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":146,"modifier":"EXACT"},"end":{"value":146,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ANC96972.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"26322073","citationType":"journal article","authors":["Li F.W.","Rothfels C.J.","Melkonian M.","Villarreal J.C.","Stevenson D.W.","Graham S.W.","Wong G.K.","Mathews S.","Pryer K.M."],"citationCrossReferences":[{"database":"PubMed","id":"26322073"}],"title":"The origin and evolution of phototropins.","publicationDate":"2015","journal":"Front. Plant Sci.","firstPage":"637","lastPage":"637","volume":"6"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ANC96972.1"}]},{"referenceNumber":2,"citation":{"id":"CI-F1K69Q5IC8RGR","citationType":"submission","authors":["Noorani M."],"publicationDate":"JUL-2015","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ANC96972.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KT321847","properties":[{"key":"ProteinId","value":"ANC96972.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A160JN66","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0004674","properties":[{"key":"GoTerm","value":"F:protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"CDD","id":"cd05574","properties":[{"key":"EntryName","value":"STKc_phototropin_like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000265","properties":[{"key":"EntryName","value":"Putative LOV domain-containing protein"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.450.20","properties":[{"key":"EntryName","value":"PAS domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR45637","properties":[{"key":"EntryName","value":"FLIPPASE KINASE 1-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"FLQGPFWNLFHLQAMKDHKGELQYFIGVQLDGSEKVEPSMKRLSEKTELESSKLVQATAVDVKEAVRELPDANSIPDDLWAKHSKVVVPKPHKINSNTWEAIRKVRTHGEKLGLKHFHPVKLLGYGDTGCVHLVELRGTGINYAMKAMSKSVMLNRNKVHRVCAEREILGMMDHPFLPTLYASFQTKTHIFLVTDFCAGGDLFLLLDRQPSKCFTEDAARFYAAEILLALEYLHCLGVIYRDLKPENVLIQIDGHLLLTDFDLSLLTSSKPQLIRPGRPTGNPKKQKDVLLPTFIAEPVARSNSFVGTEEYIAPEIINGEGHSSAVDWWALGILIYEMLYGYTPFRGKSRQKTFSNVLLKELAFPNSVTVSLAAKNLIRGLLQKDPEKRLGSKRGSNHIKHHPFFQSIKWPLIRCMSPPQLVAPVQLTSLEKDVPSKTADFEWDKIQGVNDFSREIF","length":457,"molWeight":51694,"crc64":"58D8EA98C4E332D1","md5":"80A2112948C24438F74ED609DC276631"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":2,"SIMILARITY":2},"countByFeatureType":{"Domain":1,"Active site":1,"Binding site":1,"Non-terminal residue":1},"uniParcId":"UPI0007C18424"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A8U0DD35","uniProtkbId":"A0A8U0DD35_PHYDU","entryAudit":{"firstPublicDate":"2022-10-12","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2022-10-12","entryVersion":12,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Phylloglossum drummondii","commonName":"Pigmy clubmoss","synonyms":["Huperzia drummondii"],"taxonId":70003,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"UPQ49781.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Lycopodiopsida","Lycopodiales","Lycopodiaceae","Huperzioideae","Phylloglossum"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"UPQ49781.1"}],"value":"Levopimaradiene synthase"}}]},"comments":[{"commentType":"COFACTOR","cofactors":[{"name":"Mg(2+)","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001946"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:18420"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004721"}],"value":"Secondary metabolite biosynthesis; terpenoid biosynthesis"}],"commentType":"PATHWAY"}],"features":[{"type":"Domain","location":{"start":{"value":319,"modifier":"EXACT"},"end":{"value":525,"modifier":"EXACT"}},"description":"Terpene synthase N-terminal","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF01397"}]},{"type":"Domain","location":{"start":{"value":598,"modifier":"EXACT"},"end":{"value":832,"modifier":"EXACT"}},"description":"Terpene synthase-like metal-binding","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF03936"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022842"}],"id":"KW-0460","category":"Ligand","name":"Magnesium"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-703S0ASS7I6UG","citationType":"journal article","authors":["Jia Q.","Brown R.","Koellner T.G.","Fu J.","Chen X.","Wong G.K.-S.","Gershenzon J.","Peters R.J.","Chen F."],"title":"Origin and early evolution of the plant terpene synthase family.","publicationDate":"2022","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"0","lastPage":"0","volume":"119"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"UPQ49781.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"OL989442","properties":[{"key":"ProteinId","value":"UPQ49781.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A8U0DD35","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0000287","properties":[{"key":"GoTerm","value":"F:magnesium ion binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0010333","properties":[{"key":"GoTerm","value":"F:terpene synthase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016102","properties":[{"key":"GoTerm","value":"P:diterpenoid biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd00684","properties":[{"key":"EntryName","value":"Terpene_cyclase_plant_C1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.50.10.130:FF:000002","properties":[{"key":"EntryName","value":"Ent-copalyl diphosphate synthase, chloroplastic"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.600.10:FF:000005","properties":[{"key":"EntryName","value":"Ent-kaur-16-ene synthase, chloroplastic"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.50.10.160","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.600.10","properties":[{"key":"EntryName","value":"Farnesyl Diphosphate Synthase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.50.10.130","properties":[{"key":"EntryName","value":"Terpene synthase, N-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR008949","properties":[{"key":"EntryName","value":"Isoprenoid_synthase_dom_sf"}]},{"database":"InterPro","id":"IPR034741","properties":[{"key":"EntryName","value":"Terpene_cyclase-like_1_C"}]},{"database":"InterPro","id":"IPR044814","properties":[{"key":"EntryName","value":"Terpene_cyclase_plant_C1"}]},{"database":"InterPro","id":"IPR001906","properties":[{"key":"EntryName","value":"Terpene_synth_N"}]},{"database":"InterPro","id":"IPR036965","properties":[{"key":"EntryName","value":"Terpene_synth_N_sf"}]},{"database":"InterPro","id":"IPR050148","properties":[{"key":"EntryName","value":"Terpene_synthase-like"}]},{"database":"InterPro","id":"IPR005630","properties":[{"key":"EntryName","value":"Terpene_synthase_metal-bd"}]},{"database":"InterPro","id":"IPR008930","properties":[{"key":"EntryName","value":"Terpenoid_cyclase/PrenylTrfase"}]},{"database":"PANTHER","id":"PTHR31739","properties":[{"key":"EntryName","value":"ENT-COPALYL DIPHOSPHATE SYNTHASE, CHLOROPLASTIC"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR31739:SF4","properties":[{"key":"EntryName","value":"ENT-COPALYL DIPHOSPHATE SYNTHASE, CHLOROPLASTIC"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01397","properties":[{"key":"EntryName","value":"Terpene_synth"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03936","properties":[{"key":"EntryName","value":"Terpene_synth_C"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDS00005","properties":[{"key":"EntryName","value":"Isoprenoid_Synthase_Type_I"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDG01019","properties":[{"key":"EntryName","value":"Terpene_Cyclase_Like_1_C_Termi"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDG01014","properties":[{"key":"EntryName","value":"Terpene_Cyclase_Like_1_N-term"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDG01605","properties":[{"key":"EntryName","value":"Terpene_Cyclase_Like_1_N-term"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF48239","properties":[{"key":"EntryName","value":"Terpenoid cyclases/Protein prenyltransferases"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF48576","properties":[{"key":"EntryName","value":"Terpenoid synthases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSRHGSASSYRRSDGVLMKSSSYSWPAARLWSCGDDRLALLKSSHLSSATSSKASMRKLLYAGGSKAVSACLSCISKDSTSSAIAAASRETDKNTLTEADHELQLISFEKPPSYYHPTLWKDDFIESLQGEQVDEDEINDLIEEVRGMFRTMGDGATAASAYDTAWVARVPSLDGRGSPQFPLTLQWIVDNQLEDGSWGEKELFLAYDRVFNTLACVLALQTWNVGEESITKGLDFMRRCVNMMKDEAGAHMPSGFEICFISMLEEAKQMGLDLPYDLPFIKGIQEAREKKLQRIPIDYFHTRPTTILYSLEGLQSLVDWNRILDLQSPDGSFLSSPASTACVLMHTGNQKCLDFLNSVLPRFNNAVPCHYPLDLFERLWAIDGLMRLGVDRFFQTEIKQTLDYVYKYMTETGIGWARENPVHDIDDTCMAFRILRLHGYDVSPKCIEHFKSEGKFFCFAGESRHGVTEMLNLYRASQLRFPGETILEESHSYSKAYLANAVQTRDAFDKWALKKDLEGEVEYALKFPWHRSVPRLEARTYVQQYGADDMWLGKTMYRMYNVSNQTFLELGIADFNRCQAIHQKELQQINRWWNQSGFAELSFTRQRPAEMYFSIAACMFEPEFAALRLAYTKTACITVILDDLFDSHASVPDLKLFLEAVKRWDPSVVNGLSEDMKVSFNGLYSTLNSFVEDAFEVQGRDISGYLRTTWEDLLSAYILEAEWSERSYVPKFEEYIENAKVSIALGTVILNSIFFCGEPLPDHVLQQLDFRSNFLHLVCLTGRLINDTKTFEAEKERGELASSISCYMNDNPSVSEEESKAHVYGIIDAALKELNWELVRPNNVPLPCKRLLFNTARVMQLFYMVRDGFGISDMEMKGHLHNVLFQQVSV","length":890,"molWeight":101385,"crc64":"035DB9ED4441E32C","md5":"61E59DF74A244C2AC7B93C3C34EFA4A9"},"extraAttributes":{"countByCommentType":{"COFACTOR":1,"PATHWAY":1},"countByFeatureType":{"Domain":2},"uniParcId":"UPI00204968C4"}}]}