{"results":[{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P69572","secondaryAccessions":["P92398","P92402","P92409","P92410"],"uniProtkbId":"RBL_LUPAA","entryAudit":{"firstPublicDate":"2005-03-29","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2005-03-29","entryVersion":72,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Lupinus atlanticus","commonName":"Lupine","taxonId":53218,"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Fabales","Fabaceae","Papilionoideae","50 kb inversion clade","genistoids sensu lato","core genistoids","Genisteae","Lupinus"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"value":"Ribulose bisphosphate carboxylase large chain"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"value":"RuBisCO large subunit"}],"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"value":"4.1.1.39"}]},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"value":"rbcL"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"value":"RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"2 (2R)-3-phosphoglycerate + 2 H(+) = D-ribulose 1,5-bisphosphate + CO2 + H2O","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:23124"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:16526"},{"database":"ChEBI","id":"CHEBI:57870"},{"database":"ChEBI","id":"CHEBI:58272"}],"ecNumber":"4.1.1.39","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"D-ribulose 1,5-bisphosphate + O2 = 2-phosphoglycolate + (2R)-3-phosphoglycerate + 2 H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:36631"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:15379"},{"database":"ChEBI","id":"CHEBI:57870"},{"database":"ChEBI","id":"CHEBI:58033"},{"database":"ChEBI","id":"CHEBI:58272"}],"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"Mg(2+)","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:18420"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"value":"Binds 1 Mg(2+) ion per subunit."}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"value":"Heterohexadecamer of 8 large chains and 8 small chains; disulfide-linked. The disulfide link is formed within the large subunit homodimers"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"value":"Plastid, chloroplast","id":"SL-0049"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"value":"The disulfide bond which can form in the large chain dimeric partners within the hexadecamer appears to be associated with oxidative stress and protein turnover"}],"commentType":"PTM"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"value":"The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'"}],"commentType":"MISCELLANEOUS"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"value":"Belongs to the RuBisCO large chain family. Type I subfamily"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"OUTSIDE"},"end":{"value":455,"modifier":"OUTSIDE"}},"description":"Ribulose bisphosphate carboxylase large chain","featureId":"PRO_0000062505"},{"type":"Active site","location":{"start":{"value":166,"modifier":"EXACT"},"end":{"value":166,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}]},{"type":"Active site","location":{"start":{"value":285,"modifier":"EXACT"},"end":{"value":285,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}]},{"type":"Binding site","location":{"start":{"value":114,"modifier":"EXACT"},"end":{"value":114,"modifier":"EXACT"}},"description":"in homodimeric partner","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"ligand":{"name":"substrate"}},{"type":"Binding site","location":{"start":{"value":164,"modifier":"EXACT"},"end":{"value":164,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"ligand":{"name":"substrate"}},{"type":"Binding site","location":{"start":{"value":168,"modifier":"EXACT"},"end":{"value":168,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"ligand":{"name":"substrate"}},{"type":"Binding site","location":{"start":{"value":192,"modifier":"EXACT"},"end":{"value":192,"modifier":"EXACT"}},"description":"via carbamate group","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:18420"}],"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"ligand":{"name":"Mg(2+)","id":"ChEBI:CHEBI:18420"}},{"type":"Binding site","location":{"start":{"value":194,"modifier":"EXACT"},"end":{"value":194,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:18420"}],"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"ligand":{"name":"Mg(2+)","id":"ChEBI:CHEBI:18420"}},{"type":"Binding site","location":{"start":{"value":195,"modifier":"EXACT"},"end":{"value":195,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:18420"}],"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"ligand":{"name":"Mg(2+)","id":"ChEBI:CHEBI:18420"}},{"type":"Binding site","location":{"start":{"value":286,"modifier":"EXACT"},"end":{"value":286,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"ligand":{"name":"substrate"}},{"type":"Binding site","location":{"start":{"value":318,"modifier":"EXACT"},"end":{"value":318,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"ligand":{"name":"substrate"}},{"type":"Binding site","location":{"start":{"value":370,"modifier":"EXACT"},"end":{"value":370,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}],"ligand":{"name":"substrate"}},{"type":"Site","location":{"start":{"value":325,"modifier":"EXACT"},"end":{"value":325,"modifier":"EXACT"}},"description":"Transition state stabilizer","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}]},{"type":"Modified residue","location":{"start":{"value":5,"modifier":"EXACT"},"end":{"value":5,"modifier":"EXACT"}},"description":"N6,N6,N6-trimethyllysine","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}]},{"type":"Modified residue","location":{"start":{"value":192,"modifier":"EXACT"},"end":{"value":192,"modifier":"EXACT"}},"description":"N6-carboxylysine","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}]},{"type":"Disulfide bond","location":{"start":{"value":238,"modifier":"EXACT"},"end":{"value":238,"modifier":"EXACT"}},"description":"Interchain; in linked form","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01338"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":""},{"type":"Non-terminal residue","location":{"start":{"value":455,"modifier":"EXACT"},"end":{"value":455,"modifier":"EXACT"}},"description":""}],"geneLocations":[{"geneEncodingType":"Chloroplast"}],"keywords":[{"id":"KW-0113","category":"Biological process","name":"Calvin cycle"},{"id":"KW-0120","category":"Biological process","name":"Carbon dioxide fixation"},{"id":"KW-0150","category":"Cellular component","name":"Chloroplast"},{"id":"KW-1015","category":"PTM","name":"Disulfide bond"},{"id":"KW-0456","category":"Molecular function","name":"Lyase"},{"id":"KW-0460","category":"Ligand","name":"Magnesium"},{"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"id":"KW-0488","category":"PTM","name":"Methylation"},{"id":"KW-0503","category":"Molecular function","name":"Monooxygenase"},{"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"id":"KW-0601","category":"Biological process","name":"Photorespiration"},{"id":"KW-0602","category":"Biological process","name":"Photosynthesis"},{"id":"KW-0934","category":"Cellular component","name":"Plastid"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-DJOHB36221L2E","citationType":"journal article","authors":["Kaess E.","Wink M."],"title":"Molecular phylogeny of the Papilionoideae (family Leguminosae): rbcL sequences versus chemical taxonomy.","publicationDate":"1995","journal":"Bot. Acta","firstPage":"149","lastPage":"162","volume":"108"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"Leaf","type":"TISSUE"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"Z70069","properties":[{"key":"ProteinId","value":"CAA93928.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"P69572","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P69572","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0009507","properties":[{"key":"GoTerm","value":"C:chloroplast"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0000287","properties":[{"key":"GoTerm","value":"F:magnesium ion binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016984","properties":[{"key":"GoTerm","value":"F:ribulose-bisphosphate carboxylase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0015977","properties":[{"key":"GoTerm","value":"P:carbon fixation"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd08212","properties":[{"key":"EntryName","value":"RuBisCO_large_I"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.20.20.110:FF:000001","properties":[{"key":"EntryName","value":"Ribulose bisphosphate carboxylase large chain"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.70.150:FF:000001","properties":[{"key":"EntryName","value":"Ribulose bisphosphate carboxylase large chain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.20.20.110","properties":[{"key":"EntryName","value":"Ribulose bisphosphate carboxylase, large subunit, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.70.150","properties":[{"key":"EntryName","value":"RuBisCO large subunit, N-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"HAMAP","id":"MF_01338","properties":[{"key":"EntryName","value":"RuBisCO_L_type1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR033966","properties":[{"key":"EntryName","value":"RuBisCO"}]},{"database":"InterPro","id":"IPR020878","properties":[{"key":"EntryName","value":"RuBisCo_large_chain_AS"}]},{"database":"InterPro","id":"IPR000685","properties":[{"key":"EntryName","value":"RuBisCO_lsu_C"}]},{"database":"InterPro","id":"IPR036376","properties":[{"key":"EntryName","value":"RuBisCO_lsu_C_sf"}]},{"database":"InterPro","id":"IPR017443","properties":[{"key":"EntryName","value":"RuBisCO_lsu_fd_N"}]},{"database":"InterPro","id":"IPR036422","properties":[{"key":"EntryName","value":"RuBisCO_lsu_N_sf"}]},{"database":"InterPro","id":"IPR020888","properties":[{"key":"EntryName","value":"RuBisCO_lsuI"}]},{"database":"NCBIfam","id":"NF003252","properties":[{"key":"EntryName","value":"PRK04208.1"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42704","properties":[{"key":"EntryName","value":"RIBULOSE BISPHOSPHATE CARBOXYLASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42704:SF16","properties":[{"key":"EntryName","value":"RIBULOSE BISPHOSPHATE CARBOXYLASE LARGE CHAIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00016","properties":[{"key":"EntryName","value":"RuBisCO_large"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02788","properties":[{"key":"EntryName","value":"RuBisCO_large_N"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDG01052","properties":[{"key":"EntryName","value":"RuBisCO"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDS00014","properties":[{"key":"EntryName","value":"RuBisCO"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDG00301","properties":[{"key":"EntryName","value":"RuBisCO-like_proteins"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF51649","properties":[{"key":"EntryName","value":"RuBisCo, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF54966","properties":[{"key":"EntryName","value":"RuBisCO, large subunit, small (N-terminal) domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00157","properties":[{"key":"EntryName","value":"RUBISCO_LARGE"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"SVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPNAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLASEGNQIIREASKWSPELAAACEVWKE","length":455,"molWeight":50288,"crc64":"F598938FD1D2ECCA","md5":"427AE95E7D8DEA7A587E620DA7BF61D7"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":2,"COFACTOR":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"PTM":1,"MISCELLANEOUS":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Active site":2,"Binding site":9,"Site":1,"Modified residue":2,"Disulfide bond":1,"Non-terminal residue":2},"uniParcId":"UPI00001332D5"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A142IK52","uniProtkbId":"A0A142IK52_LUPAA","entryAudit":{"firstPublicDate":"2016-06-08","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2016-06-08","entryVersion":35,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Lupinus atlanticus","commonName":"Lupine","taxonId":53218,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AMR60615.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Fabales","Fabaceae","Papilionoideae","50 kb inversion clade","genistoids sensu lato","core genistoids","Genisteae","Lupinus"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AMR60615.1"}],"value":"Lysin motif receptor-like kinase 3"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AMR60615.1"}],"value":"LYR3"}}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004162"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004162"}],"value":"Single-pass membrane protein","id":"SL-9904"}}]}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":24,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":25,"modifier":"EXACT"},"end":{"value":634,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5007497606"},{"type":"Transmembrane","location":{"start":{"value":265,"modifier":"EXACT"},"end":{"value":287,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Domain","location":{"start":{"value":186,"modifier":"EXACT"},"end":{"value":231,"modifier":"EXACT"}},"description":"LysM","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51782"}]},{"type":"Domain","location":{"start":{"value":295,"modifier":"EXACT"},"end":{"value":621,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":240,"modifier":"EXACT"},"end":{"value":259,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023157"}],"id":"KW-1015","category":"PTM","name":"Disulfide bond"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AMR60615.1"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AMR60615.1"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AMR60615.1"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"26987814","citationType":"journal article","authors":["Malkov N.","Fliegmann J.","Rosenberg C.","Gasciolli V.","Timmers A.C.","Nurisso A.","Cullimore J.","Bono J.J."],"citationCrossReferences":[{"database":"PubMed","id":"26987814"}],"title":"Molecular Basis of Lipo-chitooligosaccharide Recognition by the Lysin Motif Receptor-like Kinase LYR3 in Legumes.","publicationDate":"2016","journal":"Biochem. J.","firstPage":"0","lastPage":"0","volume":"0"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AMR60615.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KT955016","properties":[{"key":"ProteinId","value":"AMR60615.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A0A142IK52","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A0A142IK52","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0051707","properties":[{"key":"GoTerm","value":"P:response to other organism"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd00118","properties":[{"key":"EntryName","value":"LysM"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000468","properties":[{"key":"EntryName","value":"PTI1-like tyrosine-protein kinase 3"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.10.350.10","properties":[{"key":"EntryName","value":"LysM domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR018392","properties":[{"key":"EntryName","value":"LysM"}]},{"database":"InterPro","id":"IPR056562","properties":[{"key":"EntryName","value":"LysM2_CERK1_LYK3_4_5"}]},{"database":"InterPro","id":"IPR056563","properties":[{"key":"EntryName","value":"LysM3_LYK4_5"}]},{"database":"InterPro","id":"IPR036779","properties":[{"key":"EntryName","value":"LysM_dom_sf"}]},{"database":"InterPro","id":"IPR056561","properties":[{"key":"EntryName","value":"NFP_LYK_LysM1"}]},{"database":"InterPro","id":"IPR052611","properties":[{"key":"EntryName","value":"Plant_RLK_LysM"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"PANTHER","id":"PTHR45927:SF11","properties":[{"key":"EntryName","value":"LYSM DOMAIN RECEPTOR-LIKE KINASE 4"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR45927","properties":[{"key":"EntryName","value":"LYSM-DOMAIN RECEPTOR-LIKE KINASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF23446","properties":[{"key":"EntryName","value":"LysM1_NFP_LYK"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF23472","properties":[{"key":"EntryName","value":"LysM2_CERK1_LYK3_4_5"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF23473","properties":[{"key":"EntryName","value":"LysM3_LYK4_5"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00257","properties":[{"key":"EntryName","value":"LysM"},{"key":"MatchStatus","value":"2"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF54106","properties":[{"key":"EntryName","value":"LysM domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51782","properties":[{"key":"EntryName","value":"LYSM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSHFPLIPAFIFTLFICTFSMIQGQQPYIGLGTTACYKKGNSNSIRGYTCNGANQSCQAYLTFRSQPLYNSVSKISALLSSDPPQLAEINSVSLNDTFETNKLVIVPIKCSCASEYYQANTSYVVQNADTHFLIASNTFEGLSTCQALQNENHNPWNMFQGRELVVPLRCACPTRNQTEKGVKYLLSYLVKEGDSVSFISEKFDVKTKTTLEANNLSMTNDIIHPFTTLLVPLHDKPSISQTVSSAPPPSFPSSSTTDKSSKKKWVYAVVAVGVIVLILVICAIIFYTHHRKMKNKKDHVTVSESFEAIEKSQGRRKKEEESKKLSEIISGIAQSFKVYDFEELKHATDNFNPSYCIEGSVFRGVINGDLAAIKKVEGNVSKEIELLNKVNHANVIRLSGVSFSEGHWYHVYEYAANGALSEWIYFNNNIDGKFLSWTKRIQIAFDVATGLDYLHSFTSPPHIHKDLKSSNILLDHDLRAKVANLRLAKSVEVQEGEQLPLTRHIVGTRGYMAPEYLENGLVSTKLDVYAFGVLLLELLTGKEVAAILTEDNKNLSHVLCDMVGEKNDQEKVKEFMDPSLKGNYPLELAMFVVRMIDNCIEKDPENRPNMYEIVLSLSRTLNSSLSWEMSVNIS","length":634,"molWeight":71025,"crc64":"E52680816BF20D5B","md5":"3D5A95E8CBD50C24BFA084DBDCB81AB2"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Signal":1,"Chain":1,"Transmembrane":1,"Domain":2,"Region":1},"uniParcId":"UPI00078BCA41"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"F6LP11","uniProtkbId":"F6LP11_LUPAA","entryAudit":{"firstPublicDate":"2011-07-27","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2011-07-27","entryVersion":28,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Lupinus atlanticus","commonName":"Lupine","taxonId":53218,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13068.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Fabales","Fabaceae","Papilionoideae","50 kb inversion clade","genistoids sensu lato","core genistoids","Genisteae","Lupinus"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13068.1"}],"value":"Symbiotic receptor-like kinase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13068.1"}],"value":"SymRK"}}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004167"}],"value":"Membrane","id":"SL-0162"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004167"}],"value":"Single-pass membrane protein","id":"SL-9904"}}]}],"features":[{"type":"Domain","location":{"start":{"value":4,"modifier":"EXACT"},"end":{"value":294,"modifier":"EXACT"}},"description":"Malectin-like","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF12819"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13068.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":399,"modifier":"EXACT"},"end":{"value":399,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13068.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13068.1"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13068.1"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"}],"id":"KW-0732","category":"Domain","name":"Signal"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13068.1"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"21550410","citationType":"journal article","authors":["Mahe F.","Markova D.","Pasquet R.","Misset M.T.","Ainouche A."],"citationCrossReferences":[{"database":"PubMed","id":"21550410"},{"database":"DOI","id":"10.1016/j.ympev.2011.04.017"}],"title":"Isolation, phylogeny and evolution of the SymRK gene in the legume genus Lupinus L.","publicationDate":"2011","journal":"Mol. Phylogenet. Evol.","firstPage":"49","lastPage":"61","volume":"60"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13068.1"}],"value":"T1","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13068.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"JF304524","properties":[{"key":"ProteinId","value":"AEF13068.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"F6LP11","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"Gene3D","id":"2.60.120.430","properties":[{"key":"EntryName","value":"Galactose-binding lectin"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.80.10.10","properties":[{"key":"EntryName","value":"Ribonuclease Inhibitor"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR032675","properties":[{"key":"EntryName","value":"LRR_dom_sf"}]},{"database":"InterPro","id":"IPR024788","properties":[{"key":"EntryName","value":"Malectin-like_Carb-bd_dom"}]},{"database":"PANTHER","id":"PTHR45631","properties":[{"key":"EntryName","value":"OS07G0107800 PROTEIN-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR45631:SF27","properties":[{"key":"EntryName","value":"PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF12819","properties":[{"key":"EntryName","value":"Malectin_like"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52058","properties":[{"key":"EntryName","value":"L domain-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"TDYSWFSDKRSCTQISKNVSNYGSNENVRLFDIDEGKRCYHLPTTKNGVYLIRGIFPFGELSNSSFYVTIGVTQLGSVISSRLQDLGIEGVFRATKNYIDFCLVKEKVNPYISQLELRQLPEDYINGLPTSVLKLISRNNLKGEGDDIRYPVDKSDRIWKGTSNPSYALLLSSNATNFDPKTNMTPPLQVLQSALTHSEKLEFIHNDLETEGYEYRVFLYFLELNSSLKAGQRVFDIHVNSEAKEERFDILAEGSNYRYTVLNFSATGLLNLTLVKAFGSENGPLLNAYEILQVRPWIEETNQTDVEMIQKLRKEQLLQNQDNQVIQSWSGDPCIIFPWQRIACDNSSVITELDLSLSNLKGTIPFGVTEMINLKILDLSPTSFNGYIPSFTVSSVMIP","length":399,"molWeight":45233,"crc64":"E19F3D3EAB948295","md5":"DB00C538E8BC1DAD5B1B1AFCB49DA153"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Domain":1,"Non-terminal residue":2},"uniParcId":"UPI00020D64DF"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"F6LP25","uniProtkbId":"F6LP25_LUPAA","entryAudit":{"firstPublicDate":"2011-07-27","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2011-07-27","entryVersion":26,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Lupinus atlanticus","commonName":"Lupine","taxonId":53218,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13082.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Fabales","Fabaceae","Papilionoideae","50 kb inversion clade","genistoids sensu lato","core genistoids","Genisteae","Lupinus"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13082.1"}],"value":"Symbiotic receptor-like kinase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13082.1"}],"value":"SymRK"}}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004167"}],"value":"Membrane","id":"SL-0162"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004167"}],"value":"Single-pass membrane protein","id":"SL-9904"}}]}],"features":[{"type":"Domain","location":{"start":{"value":4,"modifier":"EXACT"},"end":{"value":294,"modifier":"EXACT"}},"description":"Malectin-like","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF12819"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13082.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":305,"modifier":"EXACT"},"end":{"value":305,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13082.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13082.1"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13082.1"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"}],"id":"KW-0732","category":"Domain","name":"Signal"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13082.1"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"21550410","citationType":"journal article","authors":["Mahe F.","Markova D.","Pasquet R.","Misset M.T.","Ainouche A."],"citationCrossReferences":[{"database":"PubMed","id":"21550410"},{"database":"DOI","id":"10.1016/j.ympev.2011.04.017"}],"title":"Isolation, phylogeny and evolution of the SymRK gene in the legume genus Lupinus L.","publicationDate":"2011","journal":"Mol. Phylogenet. Evol.","firstPage":"49","lastPage":"61","volume":"60"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13082.1"}],"value":"T11","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AEF13082.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"JF304538","properties":[{"key":"ProteinId","value":"AEF13082.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"F6LP25","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"Gene3D","id":"2.60.120.430","properties":[{"key":"EntryName","value":"Galactose-binding lectin"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR024788","properties":[{"key":"EntryName","value":"Malectin-like_Carb-bd_dom"}]},{"database":"PANTHER","id":"PTHR45631","properties":[{"key":"EntryName","value":"OS07G0107800 PROTEIN-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR45631:SF27","properties":[{"key":"EntryName","value":"PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF12819","properties":[{"key":"EntryName","value":"Malectin_like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"TDYSWFSDKRSCTQISKNVSNYGSNENVRLFDIDEGKRCYNLPTTKNGVYLIRGILPFGELSNSSFYVTIGVTQLGSVISSRLQDLGIEGVFRATKNYIDFCLVKEKVNPYISQLELRQLPEDYINGLPTSVLKLISRNNLKGEGDDIRYPVDKSDRIWKGTSNPSYALLLSSKATNFDPKTNMTPPLQVLQSALTHSGKGEFIHNDLEIEGYEYRVFLYFLELNSSLKAGQRVFDIHVNSEAKEERFDILAEGSNYRYTVLNFSATGLLNLTLVKAFGSENGPLLNAYEILQVRPWIEETNQTD","length":305,"molWeight":34535,"crc64":"4A269CCECF1081BD","md5":"B2783CEE2CC71236152B457A3C732DC1"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Domain":1,"Non-terminal residue":2},"uniParcId":"UPI00020D64EC"}}]}