{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"D0ETE8","uniProtkbId":"D0ETE8_9GAMM","entryAudit":{"firstPublicDate":"2009-11-24","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2009-11-24","entryVersion":40,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Thioalkalibacter halophilus","taxonId":469656,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACX49120.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Chromatiales","Thioalkalibacteraceae","Thioalkalibacter"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACX49120.1"}],"value":"Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACX49120.1"}],"value":"cbbL"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"2 (2R)-3-phosphoglycerate + 2 H(+) = D-ribulose 1,5-bisphosphate + CO2 + H2O","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:23124"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:16526"},{"database":"ChEBI","id":"CHEBI:57870"},{"database":"ChEBI","id":"CHEBI:58272"}],"ecNumber":"4.1.1.39","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10114"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"Mg(2+)","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001946"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:18420"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003834"}],"value":"Belongs to the RuBisCO large chain family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":3,"modifier":"EXACT"},"end":{"value":75,"modifier":"EXACT"}},"description":"Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF02788"}]},{"type":"Domain","location":{"start":{"value":85,"modifier":"EXACT"},"end":{"value":300,"modifier":"EXACT"}},"description":"Ribulose bisphosphate carboxylase large subunit C-terminal","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF00016"}]},{"type":"Binding site","location":{"start":{"value":134,"modifier":"EXACT"},"end":{"value":134,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:18420"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10114"}],"ligand":{"name":"Mg(2+)","id":"ChEBI:CHEBI:18420"}},{"type":"Modified residue","location":{"start":{"value":132,"modifier":"EXACT"},"end":{"value":132,"modifier":"EXACT"}},"description":"N6-carboxylysine","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10114"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACX49120.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":300,"modifier":"EXACT"},"end":{"value":300,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACX49120.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022842"}],"id":"KW-0460","category":"Ligand","name":"Magnesium"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"}],"references":[{"referenceNumber":1,"citation":{"id":"20299400","citationType":"journal article","authors":["Tourova T.P.","Kovaleva O.L.","Sorokin D.Y.","Muyzer G."],"citationCrossReferences":[{"database":"PubMed","id":"20299400"},{"database":"DOI","id":"10.1099/mic.0.034603-0"}],"title":"Ribulose-1, 5-bisphosphate carboxylase/oxygenase genes as a functional marker for chemolithoautotrophic halophilic sulfur-oxidizing bacteria in hypersaline habitats.","publicationDate":"2010","journal":"Microbiology (Mosc.)","firstPage":"0","lastPage":"0","volume":"0"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACX49120.1"}],"value":"ALCO1","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACX49120.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"GQ888605","properties":[{"key":"ProteinId","value":"ACX49120.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"D0ETE8","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0000287","properties":[{"key":"GoTerm","value":"F:magnesium ion binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016984","properties":[{"key":"GoTerm","value":"F:ribulose-bisphosphate carboxylase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0015977","properties":[{"key":"GoTerm","value":"P:carbon fixation"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.20.20.110","properties":[{"key":"EntryName","value":"Ribulose bisphosphate carboxylase, large subunit, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.70.150","properties":[{"key":"EntryName","value":"RuBisCO large subunit, N-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR033966","properties":[{"key":"EntryName","value":"RuBisCO"}]},{"database":"InterPro","id":"IPR020878","properties":[{"key":"EntryName","value":"RuBisCo_large_chain_AS"}]},{"database":"InterPro","id":"IPR000685","properties":[{"key":"EntryName","value":"RuBisCO_lsu_C"}]},{"database":"InterPro","id":"IPR036376","properties":[{"key":"EntryName","value":"RuBisCO_lsu_C_sf"}]},{"database":"InterPro","id":"IPR017443","properties":[{"key":"EntryName","value":"RuBisCO_lsu_fd_N"}]},{"database":"InterPro","id":"IPR036422","properties":[{"key":"EntryName","value":"RuBisCO_lsu_N_sf"}]},{"database":"NCBIfam","id":"NF003252","properties":[{"key":"EntryName","value":"PRK04208.1"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42704","properties":[{"key":"EntryName","value":"RIBULOSE BISPHOSPHATE CARBOXYLASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42704:SF17","properties":[{"key":"EntryName","value":"RIBULOSE BISPHOSPHATE CARBOXYLASE LARGE CHAIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00016","properties":[{"key":"EntryName","value":"RuBisCO_large"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02788","properties":[{"key":"EntryName","value":"RuBisCO_large_N"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDS00014","properties":[{"key":"EntryName","value":"RuBisCO"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDG00301","properties":[{"key":"EntryName","value":"RuBisCO-like_proteins"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF51649","properties":[{"key":"EntryName","value":"RuBisCo, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF54966","properties":[{"key":"EntryName","value":"RuBisCO, large subunit, small (N-terminal) domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00157","properties":[{"key":"EntryName","value":"RUBISCO_LARGE"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"WTDLLTDIEFYKGRAYRIEDVPGDKEAFYTFIAYPLDLFEEGSITNVLTSLVGNVFGFKAIRSLRLEDIRFPVAFLKTCMGPPSGIQVERDKLNKYGRPMLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENINCQPFMRWRNRFEFVSEAVHKAADETGEIKGHYLNVTAPDAEQMMERAEFAKELGMPIIMHDFLTAGFTANTSLAKWCRQNGMLLHIHRAMHAVIDRHPRHGIHFRVLAKCLRISGGDHLHTGTVVGKLEGDRQSTLGFVDQLREAFVPEDRSRGIFSDQDWA","length":300,"molWeight":34091,"crc64":"9A5E8F3F9418982D","md5":"1D5A6A24FD16BC9EF4D602731936FC45"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"COFACTOR":1,"SIMILARITY":1},"countByFeatureType":{"Domain":2,"Binding site":1,"Modified residue":1,"Non-terminal residue":2},"uniParcId":"UPI0001B9B3A3"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"L0GC59","uniProtkbId":"L0GC59_9GAMM","entryAudit":{"firstPublicDate":"2013-03-06","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2013-03-06","entryVersion":23,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Thioalkalibacter halophilus","taxonId":469656,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82616.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Chromatiales","Thioalkalibacteraceae","Thioalkalibacter"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82616.1"}],"value":"Sulfate thioesterase/sulfate thiohydrolase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82616.1"}],"value":"soxB"}}],"features":[{"type":"Domain","location":{"start":{"value":175,"modifier":"EXACT"},"end":{"value":240,"modifier":"EXACT"}},"description":"5'-Nucleotidase C-terminal","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF02872"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82616.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":252,"modifier":"EXACT"},"end":{"value":252,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82616.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82616.1"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"}],"references":[{"referenceNumber":1,"citation":{"id":"23237619","citationType":"journal article","authors":["Tourova T.P.","Slobodova N.V.","Bumazhkin B.K.","Kolganova T.V.","Muyzer G.","Sorokin D.Y."],"citationCrossReferences":[{"database":"PubMed","id":"23237619"},{"database":"DOI","id":"10.1111/1574-6941.12056"}],"title":"Analysis of community composition of sulfur-oxidizing bacteria in hypersaline and soda lakes using soxB as a functional molecular marker.","publicationDate":"2013","journal":"FEMS Microbiol. Ecol.","firstPage":"280","lastPage":"289","volume":"84"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82616.1"}],"value":"ALCO1","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82616.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KC017794","properties":[{"key":"ProteinId","value":"AGA82616.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"L0GC59","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0030288","properties":[{"key":"GoTerm","value":"C:outer membrane-bounded periplasmic space"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0016787","properties":[{"key":"GoTerm","value":"F:hydrolase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009166","properties":[{"key":"GoTerm","value":"P:nucleotide catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.60.21.10","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.90.780.10","properties":[{"key":"EntryName","value":"5'-Nucleotidase, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR008334","properties":[{"key":"EntryName","value":"5'-Nucleotdase_C"}]},{"database":"InterPro","id":"IPR036907","properties":[{"key":"EntryName","value":"5'-Nucleotdase_C_sf"}]},{"database":"InterPro","id":"IPR006179","properties":[{"key":"EntryName","value":"5_nucleotidase/apyrase"}]},{"database":"InterPro","id":"IPR029052","properties":[{"key":"EntryName","value":"Metallo-depent_PP-like"}]},{"database":"PANTHER","id":"PTHR11575","properties":[{"key":"EntryName","value":"5'-NUCLEOTIDASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11575:SF42","properties":[{"key":"EntryName","value":"SULFUR OXIDATION PROTEIN SOXB"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02872","properties":[{"key":"EntryName","value":"5_nucleotid_C"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR01607","properties":[{"key":"EntryName","value":"APYRASEFAMLY"}]},{"database":"SUPFAM","id":"SSF55816","properties":[{"key":"EntryName","value":"5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56300","properties":[{"key":"EntryName","value":"Metallo-dependent phosphatases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"TPIAQPSWMVEGWSFGIRESDMQQTVDAARAEGAEVVVVLSHNGMDVDIKMARNVTGIDAIFGGHTHDAPPQPTVVENEGGQTLVTNAGSNGKYLGVMDFDVQDGEIKDWNYSLLPVFSDFIEPDKEMQEYIDNLYNSEITFEGETFIAKERLEQKLASNDALLYRRGNFTGTWDQLICDALIEENDAQISFSPGVRWGTSIIPGQDITYEDMMTQTALTYPNVTVNDFTGAEIKSILEDVCDNIFNKDPYY","length":252,"molWeight":28118,"crc64":"04CAA57A3B302FAE","md5":"23AA739C4B2D6CBED8FB930EA62CEE33"},"extraAttributes":{"countByFeatureType":{"Domain":1,"Non-terminal residue":2},"uniParcId":"UPI0002A861FD"}}]}