{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"I2E7U8","uniProtkbId":"I2E7U8_9BACT","entryAudit":{"firstPublicDate":"2012-07-11","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2012-07-11","entryVersion":38,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfoconvexum algidum","taxonId":453224,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95152.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfoconvexum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95152.1"}],"value":"Dissimilatory sulfte reductase alpha subunit"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95152.1"}],"value":"dsrA"}}],"features":[{"type":"Domain","location":{"start":{"value":197,"modifier":"EXACT"},"end":{"value":225,"modifier":"EXACT"}},"description":"4Fe-4S ferredoxin-type","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51379"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95152.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022485"}],"id":"KW-0004","category":"Ligand","name":"4Fe-4S"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023014"}],"id":"KW-0411","category":"Ligand","name":"Iron-sulfur"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"}],"references":[{"referenceNumber":1,"citation":{"id":"22659505","citationType":"journal article","authors":["Konneke M.","Kuever J.","Galushko A.","Jorgensen B.B."],"citationCrossReferences":[{"database":"PubMed","id":"22659505"},{"database":"DOI","id":"10.1099/ijs.0.043703-0"}],"title":"Desulfoconvexum algidum gen. nov., sp. nov., a psychrophilic sulfate-reducing bacterium isolated from a permanently cold marine sediment.","publicationDate":"2013","journal":"Int. J. Syst. Evol. Microbiol.","firstPage":"959","lastPage":"964","volume":"63"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95152.1"}],"value":"JHA1","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95152.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"JQ901403","properties":[{"key":"ProteinId","value":"AFJ95152.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"I2E7U8","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0009337","properties":[{"key":"GoTerm","value":"C:sulfite reductase complex (NADPH)"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0051539","properties":[{"key":"GoTerm","value":"F:4 iron, 4 sulfur cluster binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0018551","properties":[{"key":"GoTerm","value":"F:dissimilatory sulfite reductase (NADH) activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0020037","properties":[{"key":"GoTerm","value":"F:heme binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0050311","properties":[{"key":"GoTerm","value":"F:sulfite reductase (ferredoxin) activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0000103","properties":[{"key":"GoTerm","value":"P:sulfate assimilation"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"Gene3D","id":"3.30.70.20","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.70.2500","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.413.10","properties":[{"key":"EntryName","value":"Sulfite Reductase Hemoprotein, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR017896","properties":[{"key":"EntryName","value":"4Fe4S_Fe-S-bd"}]},{"database":"InterPro","id":"IPR011806","properties":[{"key":"EntryName","value":"DsrA"}]},{"database":"InterPro","id":"IPR036136","properties":[{"key":"EntryName","value":"Nit/Sulf_reduc_fer-like_dom_sf"}]},{"database":"InterPro","id":"IPR006067","properties":[{"key":"EntryName","value":"NO2/SO3_Rdtase_4Fe4S_dom"}]},{"database":"InterPro","id":"IPR045169","properties":[{"key":"EntryName","value":"NO2/SO3_Rdtase_4Fe4S_prot"}]},{"database":"InterPro","id":"IPR045854","properties":[{"key":"EntryName","value":"NO2/SO3_Rdtase_4Fe4S_sf"}]},{"database":"NCBIfam","id":"TIGR02064","properties":[{"key":"EntryName","value":"dsrA"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11493:SF54","properties":[{"key":"EntryName","value":"ANAEROBIC SULFITE REDUCTASE SUBUNIT C"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11493","properties":[{"key":"EntryName","value":"SULFITE REDUCTASE [NADPH] SUBUNIT BETA-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01077","properties":[{"key":"EntryName","value":"NIR_SIR"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF54862","properties":[{"key":"EntryName","value":"4Fe-4S ferredoxins"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56014","properties":[{"key":"EntryName","value":"Nitrite and sulphite reductase 4Fe-4S domain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55124","properties":[{"key":"EntryName","value":"Nitrite/Sulfite reductase N-terminal domain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51379","properties":[{"key":"EntryName","value":"4FE4S_FER_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"RVNQPAGKYYTTDYLRTLTKLWDFRGSGLTNMHGATGDIILLGTTTPQLEEVFHTLTHDMGQDLGGSGSNLRTPADCLGQSRCEYACYDTNALVYFLTNEYQDELHRPAFPYKFKFKLDGCPNCCVASIARSDMSFIGTWKDDIRIDQDAVNKYVENDPAYPANAGAYKGSKDWGPFDLEKEVLNLCPTKCMMFKNKKLFIDTANCTRCMHCINVMPRALKIGKETGCSILCGAKAPILDGAQMGSLLVPFIEVNPDNDYEAITEVIENIWDWWMEEGKNRERLGELIMRQGFQKLLEVTGIEAVPQHVQYPRTNPYIFWKEDEVPGGWERDVEEYRKHHQR","length":342,"molWeight":39014,"crc64":"B0F1F7B83E4603F8","md5":"BDC6D2EB61D4B2A682B32C00463EEBB0"},"extraAttributes":{"countByFeatureType":{"Domain":1,"Non-terminal residue":1},"uniParcId":"UPI00025F81CF"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"I2E7U9","uniProtkbId":"I2E7U9_9BACT","entryAudit":{"firstPublicDate":"2012-07-11","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2012-07-11","entryVersion":39,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfoconvexum algidum","taxonId":453224,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95153.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfoconvexum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95153.1"}],"value":"Dissimilatory sulfite reductase beta subunit"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95153.1"}],"value":"dsrB"}}],"comments":[{"commentType":"COFACTOR","cofactors":[{"name":"[4Fe-4S] cluster","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001966"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:49883"}}]},{"commentType":"COFACTOR","cofactors":[{"name":"siroheme","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001929"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:60052"}}]}],"features":[{"type":"Domain","location":{"start":{"value":58,"modifier":"EXACT"},"end":{"value":119,"modifier":"EXACT"}},"description":"Nitrite/Sulfite reductase ferredoxin-like","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF03460"}]},{"type":"Domain","location":{"start":{"value":136,"modifier":"EXACT"},"end":{"value":212,"modifier":"EXACT"}},"description":"Nitrite/sulphite reductase 4Fe-4S","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF01077"}]},{"type":"Non-terminal residue","location":{"start":{"value":227,"modifier":"EXACT"},"end":{"value":227,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95153.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022485"}],"id":"KW-0004","category":"Ligand","name":"4Fe-4S"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023014"}],"id":"KW-0411","category":"Ligand","name":"Iron-sulfur"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"}],"references":[{"referenceNumber":1,"citation":{"id":"22659505","citationType":"journal article","authors":["Konneke M.","Kuever J.","Galushko A.","Jorgensen B.B."],"citationCrossReferences":[{"database":"PubMed","id":"22659505"},{"database":"DOI","id":"10.1099/ijs.0.043703-0"}],"title":"Desulfoconvexum algidum gen. nov., sp. nov., a psychrophilic sulfate-reducing bacterium isolated from a permanently cold marine sediment.","publicationDate":"2013","journal":"Int. J. Syst. Evol. Microbiol.","firstPage":"959","lastPage":"964","volume":"63"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95153.1"}],"value":"JHA1","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AFJ95153.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"JQ901403","properties":[{"key":"ProteinId","value":"AFJ95153.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"I2E7U9","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0020037","properties":[{"key":"GoTerm","value":"F:heme binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0051536","properties":[{"key":"GoTerm","value":"F:iron-sulfur cluster binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016491","properties":[{"key":"GoTerm","value":"F:oxidoreductase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.30.70.3340","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.413.10","properties":[{"key":"EntryName","value":"Sulfite Reductase Hemoprotein, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR005117","properties":[{"key":"EntryName","value":"NiRdtase/SiRdtase_haem-b_fer"}]},{"database":"InterPro","id":"IPR036136","properties":[{"key":"EntryName","value":"Nit/Sulf_reduc_fer-like_dom_sf"}]},{"database":"InterPro","id":"IPR006067","properties":[{"key":"EntryName","value":"NO2/SO3_Rdtase_4Fe4S_dom"}]},{"database":"InterPro","id":"IPR045169","properties":[{"key":"EntryName","value":"NO2/SO3_Rdtase_4Fe4S_prot"}]},{"database":"InterPro","id":"IPR045854","properties":[{"key":"EntryName","value":"NO2/SO3_Rdtase_4Fe4S_sf"}]},{"database":"PANTHER","id":"PTHR11493:SF47","properties":[{"key":"EntryName","value":"SULFITE REDUCTASE [NADPH] SUBUNIT BETA"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11493","properties":[{"key":"EntryName","value":"SULFITE REDUCTASE [NADPH] SUBUNIT BETA-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01077","properties":[{"key":"EntryName","value":"NIR_SIR"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03460","properties":[{"key":"EntryName","value":"NIR_SIR_ferr"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56014","properties":[{"key":"EntryName","value":"Nitrite and sulphite reductase 4Fe-4S domain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55124","properties":[{"key":"EntryName","value":"Nitrite/Sulfite reductase N-terminal domain-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MAFISTGYNPAKPMENRITDIGPKDHNEFYPPVIKKNKGKWSHHEILEPGVLVHVADSGDEVYTVRCGGARLMSTTHINEMCDIADKHCDGHIRFTTRNNIEFMVDSKDKLEPLKNDLASRKFDGGSFKFPIGGTGAGVTNIVHTQGWIHCHTPATDASGTVKATMDTLFSDFQDMRLPAQLRVSMACCLNMCGAVHCSDIAILGYHRKPPMLDHEYLDKICEIPLA","length":227,"molWeight":25185,"crc64":"DC73620725848CBB","md5":"5F95097BC857F331AC737485124FF113"},"extraAttributes":{"countByCommentType":{"COFACTOR":2},"countByFeatureType":{"Domain":2,"Non-terminal residue":1},"uniParcId":"UPI00025F81D0"}}]}