{"results":[{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P80920","uniProtkbId":"ACP_LEUMU","entryAudit":{"firstPublicDate":"1997-11-01","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2007-01-23","entryVersion":105,"sequenceVersion":2},"annotationScore":4.0,"organism":{"scientificName":"Leucothrix mucor","taxonId":45248,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Thiotrichales","Thiotrichaceae","Leucothrix"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01217"}],"value":"Acyl carrier protein"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01217"}],"value":"ACP"}]}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01217"}],"value":"acpP"}}],"comments":[{"texts":[{"value":"Carrier of the growing fatty acid chain in fatty acid biosynthesis"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01217"}],"value":"Lipid metabolism; fatty acid biosynthesis"}],"commentType":"PATHWAY"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01217"}],"value":"Cytoplasm","id":"SL-0086"}}]},{"texts":[{"value":"4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group"}],"commentType":"PTM"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01217"}],"value":"Belongs to the acyl carrier protein (ACP) family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Initiator methionine","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"Removed","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9171419"}]},{"type":"Chain","location":{"start":{"value":2,"modifier":"EXACT"},"end":{"value":77,"modifier":"EXACT"}},"description":"Acyl carrier protein","featureId":"PRO_0000180149"},{"type":"Domain","location":{"start":{"value":2,"modifier":"EXACT"},"end":{"value":77,"modifier":"EXACT"}},"description":"Carrier","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00258"}]},{"type":"Modified residue","location":{"start":{"value":37,"modifier":"EXACT"},"end":{"value":37,"modifier":"EXACT"}},"description":"O-(pantetheine 4'-phosphoryl)serine","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00258"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9171419"}]}],"keywords":[{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0903","category":"Technical term","name":"Direct protein sequencing"},{"id":"KW-0275","category":"Biological process","name":"Fatty acid biosynthesis"},{"id":"KW-0276","category":"Biological process","name":"Fatty acid metabolism"},{"id":"KW-0444","category":"Biological process","name":"Lipid biosynthesis"},{"id":"KW-0443","category":"Biological process","name":"Lipid metabolism"},{"id":"KW-0596","category":"PTM","name":"Phosphopantetheine"},{"id":"KW-0597","category":"PTM","name":"Phosphoprotein"}],"references":[{"referenceNumber":1,"citation":{"id":"9171419","citationType":"journal article","authors":["Tang L.","Weissborn A.C.","Kennedy E.P."],"citationCrossReferences":[{"database":"PubMed","id":"9171419"},{"database":"DOI","id":"10.1128/jb.179.11.3697-3705.1997"}],"title":"Domains of Escherichia coli acyl carrier protein important for membrane-derived-oligosaccharide biosynthesis.","publicationDate":"1997","journal":"J. Bacteriol.","firstPage":"3697","lastPage":"3705","volume":"179"},"referencePositions":["PROTEIN SEQUENCE OF 2-77","PHOSPHOPANTETHEINYLATION AT SER-37"],"referenceComments":[{"value":"ATCC 25107 / DSM 2157 / CECT 5016 / NCIMB 2222","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"AlphaFoldDB","id":"P80920","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P80920","properties":[{"key":"Description","value":"-"}]},{"database":"UniPathway","id":"UPA00094","properties":[{"key":"RectionId","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0000035","properties":[{"key":"GoTerm","value":"F:acyl binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0000036","properties":[{"key":"GoTerm","value":"F:acyl carrier activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0031177","properties":[{"key":"GoTerm","value":"F:phosphopantetheine binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009245","properties":[{"key":"GoTerm","value":"P:lipid A biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"FunFam","id":"1.10.1200.10:FF:000001","properties":[{"key":"EntryName","value":"Acyl carrier protein"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.1200.10","properties":[{"key":"EntryName","value":"ACP-like"},{"key":"MatchStatus","value":"1"}]},{"database":"HAMAP","id":"MF_01217","properties":[{"key":"EntryName","value":"Acyl_carrier"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003231","properties":[{"key":"EntryName","value":"ACP"}]},{"database":"InterPro","id":"IPR036736","properties":[{"key":"EntryName","value":"ACP-like_sf"}]},{"database":"InterPro","id":"IPR020806","properties":[{"key":"EntryName","value":"PKS_PP-bd"}]},{"database":"InterPro","id":"IPR009081","properties":[{"key":"EntryName","value":"PP-bd_ACP"}]},{"database":"InterPro","id":"IPR006162","properties":[{"key":"EntryName","value":"Ppantetheine_attach_site"}]},{"database":"NCBIfam","id":"NF002149","properties":[{"key":"EntryName","value":"acpP"},{"key":"MatchStatus","value":"1"}]},{"database":"NCBIfam","id":"TIGR00517","properties":[{"key":"EntryName","value":"acyl_carrier"},{"key":"MatchStatus","value":"1"}]},{"database":"NCBIfam","id":"NF002148","properties":[{"key":"EntryName","value":"PRK00982.1-2"},{"key":"MatchStatus","value":"1"}]},{"database":"NCBIfam","id":"NF002150","properties":[{"key":"EntryName","value":"PRK00982.1-4"},{"key":"MatchStatus","value":"1"}]},{"database":"NCBIfam","id":"NF002151","properties":[{"key":"EntryName","value":"PRK00982.1-5"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR20863","properties":[{"key":"EntryName","value":"ACYL CARRIER PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR20863:SF76","properties":[{"key":"EntryName","value":"CARRIER DOMAIN-CONTAINING PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00550","properties":[{"key":"EntryName","value":"PP-binding"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00823","properties":[{"key":"EntryName","value":"PKS_PP"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF47336","properties":[{"key":"EntryName","value":"ACP-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50075","properties":[{"key":"EntryName","value":"CARRIER"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00012","properties":[{"key":"EntryName","value":"PHOSPHOPANTETHEINE"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSDIEQRVKNVVVEQLGVDEAEVTNAASFVDDLGADSLDTVELVMALEEEFGTEIPDEEAEKITTVQLAIDYVKSHQ","length":77,"molWeight":8468,"crc64":"6D71233E04EA981A","md5":"0D8FBD36D611B63E31934E08D05409F7"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"PATHWAY":1,"SUBCELLULAR LOCATION":1,"PTM":1,"SIMILARITY":1},"countByFeatureType":{"Initiator methionine":1,"Chain":1,"Domain":1,"Modified residue":1},"uniParcId":"UPI0000ED908A"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A9Q6U6","uniProtkbId":"A9Q6U6_LEUMU","entryAudit":{"firstPublicDate":"2008-02-05","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-02-05","entryVersion":36,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Leucothrix mucor","taxonId":45248,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67350.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Thiotrichales","Thiotrichaceae","Leucothrix"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67350.1"}],"value":"Sulfate thioesterase/sulfate thiohydrolase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67350.1"}],"value":"soxB"}}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67350.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":223,"modifier":"EXACT"},"end":{"value":223,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67350.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67350.1"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"}],"references":[{"referenceNumber":1,"citation":{"id":"17991026","citationType":"journal article","authors":["Meyer B.","Imhoff J.F.","Kuever J."],"citationCrossReferences":[{"database":"PubMed","id":"17991026"},{"database":"DOI","id":"10.1111/j.1462-2920.2007.01407.x"}],"title":"Molecular analysis of the distribution and phylogeny of the soxB gene among sulfur-oxidizing bacteria - evolution of the Sox sulfur oxidation enzyme system.","publicationDate":"2007","journal":"Environ. Microbiol.","firstPage":"2957","lastPage":"2977","volume":"9"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67350.1"}],"value":"DSM 621","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67350.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"EF618580","properties":[{"key":"ProteinId","value":"ABR67350.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A9Q6U6","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0030288","properties":[{"key":"GoTerm","value":"C:outer membrane-bounded periplasmic space"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0016787","properties":[{"key":"GoTerm","value":"F:hydrolase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009166","properties":[{"key":"GoTerm","value":"P:nucleotide catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.60.21.10","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.90.780.10","properties":[{"key":"EntryName","value":"5'-Nucleotidase, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR036907","properties":[{"key":"EntryName","value":"5'-Nucleotdase_C_sf"}]},{"database":"InterPro","id":"IPR006179","properties":[{"key":"EntryName","value":"5_nucleotidase/apyrase"}]},{"database":"InterPro","id":"IPR029052","properties":[{"key":"EntryName","value":"Metallo-depent_PP-like"}]},{"database":"PANTHER","id":"PTHR11575","properties":[{"key":"EntryName","value":"5'-NUCLEOTIDASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11575:SF42","properties":[{"key":"EntryName","value":"SULFUR OXIDATION PROTEIN SOXB"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR01607","properties":[{"key":"EntryName","value":"APYRASEFAMLY"}]},{"database":"SUPFAM","id":"SSF55816","properties":[{"key":"EntryName","value":"5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56300","properties":[{"key":"EntryName","value":"Metallo-dependent phosphatases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"FVPDWSFGIRDDRMQEMVDEARGKGAQAVILLSHNGMDVDLKLASKLTGIDAIMGGHTHDGVYQPVIVENSGGKTLVTNVGSNGKFLGVLDLEVKGGKVADFRYKLMPVFSNLLEANKGMSELIEKIRAPYQTELCEELAVCDDVLYRRGNFNGTFDQLICNALMEELDAPIAFSPGFRWGTSVLPGQPITFEHVADQTALTYGTVTRNLMSGELIKEVLEDV","length":223,"molWeight":24458,"crc64":"3EB802AD3D839BEA","md5":"413762488498D7E6D0BB9C39F6CE0EE6"},"extraAttributes":{"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI00016082B5"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A9Q6V2","uniProtkbId":"A9Q6V2_LEUMU","entryAudit":{"firstPublicDate":"2008-02-05","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-02-05","entryVersion":29,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Leucothrix mucor","taxonId":45248,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67356.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Thiotrichales","Thiotrichaceae","Leucothrix"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67356.1"}],"value":"Sulfate thioesterase/sulfate thiohydrolase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67356.1"}],"value":"soxB"}}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67356.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":223,"modifier":"EXACT"},"end":{"value":223,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67356.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67356.1"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"}],"references":[{"referenceNumber":1,"citation":{"id":"17991026","citationType":"journal article","authors":["Meyer B.","Imhoff J.F.","Kuever J."],"citationCrossReferences":[{"database":"PubMed","id":"17991026"},{"database":"DOI","id":"10.1111/j.1462-2920.2007.01407.x"}],"title":"Molecular analysis of the distribution and phylogeny of the soxB gene among sulfur-oxidizing bacteria - evolution of the Sox sulfur oxidation enzyme system.","publicationDate":"2007","journal":"Environ. Microbiol.","firstPage":"2957","lastPage":"2977","volume":"9"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67356.1"}],"value":"DSM 2157","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67356.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"EF618586","properties":[{"key":"ProteinId","value":"ABR67356.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"GO","id":"GO:0030288","properties":[{"key":"GoTerm","value":"C:outer membrane-bounded periplasmic space"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0016787","properties":[{"key":"GoTerm","value":"F:hydrolase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009166","properties":[{"key":"GoTerm","value":"P:nucleotide catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.60.21.10","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.90.780.10","properties":[{"key":"EntryName","value":"5'-Nucleotidase, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR036907","properties":[{"key":"EntryName","value":"5'-Nucleotdase_C_sf"}]},{"database":"InterPro","id":"IPR006179","properties":[{"key":"EntryName","value":"5_nucleotidase/apyrase"}]},{"database":"InterPro","id":"IPR029052","properties":[{"key":"EntryName","value":"Metallo-depent_PP-like"}]},{"database":"PANTHER","id":"PTHR11575","properties":[{"key":"EntryName","value":"5'-NUCLEOTIDASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11575:SF42","properties":[{"key":"EntryName","value":"SULFUR OXIDATION PROTEIN SOXB"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55816","properties":[{"key":"EntryName","value":"5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56300","properties":[{"key":"EntryName","value":"Metallo-dependent phosphatases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"FVPDWSFGIRDDRMQEMVDEARGKGAQAVILLSHNGMDVDLKLASKLTGIDAIMGGHTHDGVYQPVIVENSGGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEDVLYRRGNFNGTFDQVICNALMEELDAQITFSPGFRWGTSVLPGHPITFEHVADQTALTYGTVTRNLMSGELIKEVLEDV","length":223,"molWeight":24625,"crc64":"C5F710A2B0DE6E44","md5":"BC225B1B811540871ABD4972331BC16A"},"extraAttributes":{"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI00016082BB"}}]}