{"results":[{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P0A0T1","secondaryAccessions":["O68824"],"uniProtkbId":"G6PI_XANCI","entryAudit":{"firstPublicDate":"2005-02-15","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2005-02-15","entryVersion":65,"sequenceVersion":1},"annotationScore":4.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"Glucose-6-phosphate isomerase"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"GPI"}],"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"5.3.1.9"}]},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"Phosphoglucose isomerase"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"PGI"}]},{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"Phosphohexose isomerase"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"PHI"}]}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"pgi"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate"}],"commentType":"FUNCTION"},{"texts":[{"value":"Required for pathogenicity"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:11816"},{"database":"ChEBI","id":"CHEBI:57634"},{"database":"ChEBI","id":"CHEBI:58225"}],"ecNumber":"5.3.1.9","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"Carbohydrate biosynthesis; gluconeogenesis"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4"}],"commentType":"PATHWAY"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}],"value":"Cytoplasm","id":"SL-0086"}}]},{"texts":[{"value":"Inhibited by growth in complex medium but induced by culture in plant extract"}],"commentType":"INDUCTION"},{"texts":[{"value":"Mutation in pgi results in the inability of X.c.citri to utilize fructose or glycerol as carbon sources, to grow in plant tissue, and to cause typical canker symptoms"}],"commentType":"MISCELLANEOUS"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"},{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the GPI family"}],"commentType":"SIMILARITY"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"AAC08426.1","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":504,"modifier":"EXACT"}},"description":"Glucose-6-phosphate isomerase","featureId":"PRO_0000180771"},{"type":"Active site","location":{"start":{"value":333,"modifier":"EXACT"},"end":{"value":333,"modifier":"EXACT"}},"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}]},{"type":"Active site","location":{"start":{"value":364,"modifier":"EXACT"},"end":{"value":364,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}]},{"type":"Active site","location":{"start":{"value":473,"modifier":"EXACT"},"end":{"value":473,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00473"}]}],"keywords":[{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0312","category":"Biological process","name":"Gluconeogenesis"},{"id":"KW-0324","category":"Biological process","name":"Glycolysis"},{"id":"KW-0413","category":"Molecular function","name":"Isomerase"}],"references":[{"referenceNumber":1,"citation":{"id":"10584018","citationType":"journal article","authors":["Tung S.Y.","Kuo T.T."],"citationCrossReferences":[{"database":"PubMed","id":"10584018"},{"database":"DOI","id":"10.1128/aem.65.12.5564-5573.1999"}],"title":"Requirement for phosphoglucose isomerase of Xanthomonas campestris in pathogenesis of citrus canker.","publicationDate":"1999","journal":"Appl. Environ. Microbiol.","firstPage":"5564","lastPage":"5570","volume":"65"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]","CHARACTERIZATION"],"referenceComments":[{"value":"XW47","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AF054807","properties":[{"key":"ProteinId","value":"AAC08426.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"T46970","properties":[{"key":"EntryName","value":"T46970"}]},{"database":"RefSeq","id":"WP_011051139.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP059992.1"}]},{"database":"AlphaFoldDB","id":"P0A0T1","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P0A0T1","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"66910936","properties":[{"key":"Description","value":"-"}]},{"database":"UniPathway","id":"UPA00109","properties":[{"key":"RectionId","value":"UER00181"}]},{"database":"UniPathway","id":"UPA00138","properties":[{"key":"RectionId","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0097367","properties":[{"key":"GoTerm","value":"F:carbohydrate derivative binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0004347","properties":[{"key":"GoTerm","value":"F:glucose-6-phosphate isomerase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0048029","properties":[{"key":"GoTerm","value":"F:monosaccharide binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006094","properties":[{"key":"GoTerm","value":"P:gluconeogenesis"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0051156","properties":[{"key":"GoTerm","value":"P:glucose 6-phosphate metabolic process"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006096","properties":[{"key":"GoTerm","value":"P:glycolytic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"CDD","id":"cd05015","properties":[{"key":"EntryName","value":"SIS_PGI_1"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd05016","properties":[{"key":"EntryName","value":"SIS_PGI_2"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.40.50.10490:FF:000060","properties":[{"key":"EntryName","value":"Glucose-6-phosphate isomerase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.1390.10","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.10490","properties":[{"key":"EntryName","value":"Glucose-6-phosphate isomerase like protein, domain 1"},{"key":"MatchStatus","value":"2"}]},{"database":"HAMAP","id":"MF_00473","properties":[{"key":"EntryName","value":"G6P_isomerase"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR001672","properties":[{"key":"EntryName","value":"G6P_Isomerase"}]},{"database":"InterPro","id":"IPR023096","properties":[{"key":"EntryName","value":"G6P_Isomerase_C"}]},{"database":"InterPro","id":"IPR018189","properties":[{"key":"EntryName","value":"Phosphoglucose_isomerase_CS"}]},{"database":"InterPro","id":"IPR046348","properties":[{"key":"EntryName","value":"SIS_dom_sf"}]},{"database":"InterPro","id":"IPR035476","properties":[{"key":"EntryName","value":"SIS_PGI_1"}]},{"database":"InterPro","id":"IPR035482","properties":[{"key":"EntryName","value":"SIS_PGI_2"}]},{"database":"NCBIfam","id":"NF001211","properties":[{"key":"EntryName","value":"pgi"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11469","properties":[{"key":"EntryName","value":"GLUCOSE-6-PHOSPHATE ISOMERASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11469:SF1","properties":[{"key":"EntryName","value":"GLUCOSE-6-PHOSPHATE ISOMERASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00342","properties":[{"key":"EntryName","value":"PGI"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00662","properties":[{"key":"EntryName","value":"G6PISOMERASE"}]},{"database":"SUPFAM","id":"SSF53697","properties":[{"key":"EntryName","value":"SIS domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00765","properties":[{"key":"EntryName","value":"P_GLUCOSE_ISOMERASE_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00174","properties":[{"key":"EntryName","value":"P_GLUCOSE_ISOMERASE_2"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51463","properties":[{"key":"EntryName","value":"P_GLUCOSE_ISOMERASE_3"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MTQTNGFDALHAHAQRLRGAAIPALLAAEPERPTQYARQVGPLYFNFARQKYDRAALDALFAIARERDLSGAFQRLFRGEQVNVTEQRAALHTALRGDLTDAPVASEAYATAEEVRQRMGSLIQQLEATDVTDIVSVGIGGSDLGPRLVADALRAPSGARFRVHFVSNVDGAAMQRTLATLDPARTAGILISKTFGTQETLLNGSILHAWLGGSERLYAVSANPERAAKAFDIAPGRVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLEGAAQFDAHVLNTPLEENVAVLHGLTAVWNRNLLGSATHAVMTYDQRLALLPAYLQQLVMESLGKRVKLDGSAVDSDTVSVWWGGAGTDVQHSFFQALHQGTSVVPADFIGTVHNDDPYAENHTALMANVLAQTEALANGQDSSDPHRSYPGGRPSTVILLDALTPQALGALISMYEHSVYVQSVMWGINAFDQFGVELGKQLASQLLPALKGESVDVADPVTRELLNKLRG","length":504,"molWeight":54454,"crc64":"03C410C3F8E8A504","md5":"7D583E96767ADBA541AEC100A7975574"},"extraAttributes":{"countByCommentType":{"FUNCTION":2,"CATALYTIC ACTIVITY":1,"PATHWAY":2,"SUBCELLULAR LOCATION":1,"INDUCTION":1,"MISCELLANEOUS":1,"SIMILARITY":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Chain":1,"Active site":3},"uniParcId":"UPI000012AF79"}},{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P52279","secondaryAccessions":["P96186"],"uniProtkbId":"PIP_XANCI","entryAudit":{"firstPublicDate":"1996-10-01","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"1997-11-01","entryVersion":109,"sequenceVersion":2},"annotationScore":4.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Proline iminopeptidase"},"shortNames":[{"value":"PIP"}],"ecNumbers":[{"value":"3.4.11.5"}]},"alternativeNames":[{"fullName":{"value":"Prolyl aminopeptidase"},"shortNames":[{"value":"PAP"}]}]},"genes":[{"geneName":{"value":"pip"},"synonyms":[{"value":"xap"}]}],"comments":[{"texts":[{"value":"May be involved in proline metabolism and sensitivity to ascamycin. Has ascamycin dealanylating activity"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"Release of N-terminal proline from a peptide.","ecNumber":"3.4.11.5"}},{"texts":[{"value":"Homooligomer"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Cytoplasm","id":"SL-0086"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the peptidase S33 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":313,"modifier":"EXACT"}},"description":"Proline iminopeptidase","featureId":"PRO_0000080847"},{"type":"Domain","location":{"start":{"value":35,"modifier":"EXACT"},"end":{"value":298,"modifier":"EXACT"}},"description":"AB hydrolase-1","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Active site","location":{"start":{"value":110,"modifier":"EXACT"},"end":{"value":110,"modifier":"EXACT"}},"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9427736"}]},{"type":"Active site","location":{"start":{"value":266,"modifier":"EXACT"},"end":{"value":266,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9427736"}]},{"type":"Active site","location":{"start":{"value":294,"modifier":"EXACT"},"end":{"value":294,"modifier":"EXACT"}},"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9427736"}]},{"type":"Sequence conflict","location":{"start":{"value":95,"modifier":"EXACT"},"end":{"value":95,"modifier":"EXACT"}},"description":"in Ref. 3; BAA11623","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"L","alternativeSequences":["V"]}},{"type":"Sequence conflict","location":{"start":{"value":121,"modifier":"EXACT"},"end":{"value":129,"modifier":"EXACT"}},"description":"in Ref. 3; BAA11623","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"ADPSAAGHQ","alternativeSequences":["QTHPQQVTE"]}},{"type":"Sequence conflict","location":{"start":{"value":245,"modifier":"EXACT"},"end":{"value":251,"modifier":"EXACT"}},"description":"in Ref. 3; BAA11623","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"QLLRDAH","alternativeSequences":["SCCATD"]}},{"type":"Sequence conflict","location":{"start":{"value":284,"modifier":"EXACT"},"end":{"value":284,"modifier":"EXACT"}},"description":"in Ref. 3; BAA11623","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{}},{"type":"Helix","location":{"start":{"value":4,"modifier":"EXACT"},"end":{"value":7,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":11,"modifier":"EXACT"},"end":{"value":17,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":19,"modifier":"EXACT"},"end":{"value":21,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":23,"modifier":"EXACT"},"end":{"value":30,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":34,"modifier":"EXACT"},"end":{"value":40,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Turn","location":{"start":{"value":43,"modifier":"EXACT"},"end":{"value":46,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":50,"modifier":"EXACT"},"end":{"value":55,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Turn","location":{"start":{"value":58,"modifier":"EXACT"},"end":{"value":60,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":61,"modifier":"EXACT"},"end":{"value":66,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":74,"modifier":"EXACT"},"end":{"value":76,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":85,"modifier":"EXACT"},"end":{"value":98,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":102,"modifier":"EXACT"},"end":{"value":109,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":111,"modifier":"EXACT"},"end":{"value":122,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":124,"modifier":"EXACT"},"end":{"value":126,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":127,"modifier":"EXACT"},"end":{"value":134,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":140,"modifier":"EXACT"},"end":{"value":147,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":151,"modifier":"EXACT"},"end":{"value":154,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":156,"modifier":"EXACT"},"end":{"value":164,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":168,"modifier":"EXACT"},"end":{"value":170,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":174,"modifier":"EXACT"},"end":{"value":182,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":187,"modifier":"EXACT"},"end":{"value":203,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":205,"modifier":"EXACT"},"end":{"value":208,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":211,"modifier":"EXACT"},"end":{"value":217,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":220,"modifier":"EXACT"},"end":{"value":235,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":237,"modifier":"EXACT"},"end":{"value":239,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":245,"modifier":"EXACT"},"end":{"value":248,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":250,"modifier":"EXACT"},"end":{"value":253,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":258,"modifier":"EXACT"},"end":{"value":263,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":267,"modifier":"EXACT"},"end":{"value":269,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":271,"modifier":"EXACT"},"end":{"value":280,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Beta strand","location":{"start":{"value":284,"modifier":"EXACT"},"end":{"value":289,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]},{"type":"Helix","location":{"start":{"value":299,"modifier":"EXACT"},"end":{"value":312,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1AZW"}]}],"keywords":[{"id":"KW-0002","category":"Technical term","name":"3D-structure"},{"id":"KW-0031","category":"Molecular function","name":"Aminopeptidase"},{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0903","category":"Technical term","name":"Direct protein sequencing"},{"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"id":"KW-0645","category":"Molecular function","name":"Protease"}],"references":[{"referenceNumber":1,"citation":{"id":"8885412","citationType":"journal article","authors":["Alonso J.","Garcia J.L."],"citationCrossReferences":[{"database":"PubMed","id":"8885412"},{"database":"DOI","id":"10.1099/13500872-142-10-2951"}],"title":"Proline iminopeptidase gene from Xanthomonas campestris pv. citri.","publicationDate":"1996","journal":"Microbiology","firstPage":"2951","lastPage":"2957","volume":"142"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"NBRC 3835","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"CI-39C9SPT00IOUP","citationType":"submission","authors":["Alonso J."],"publicationDate":"FEB-1997","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["SEQUENCE REVISION"]},{"referenceNumber":3,"citation":{"id":"8870654","citationType":"journal article","authors":["Sudo T.","Shinohara K.","Dohmae N.","Takio K.","Usami R.","Horikoshi K.","Osada H."],"citationCrossReferences":[{"database":"PubMed","id":"8870654"},{"database":"DOI","id":"10.1042/bj3190099"}],"title":"Isolation and characterization of the gene encoding an aminopeptidase involved in the selective toxicity of ascamycin toward Xanthomonas campestris pv. citri.","publicationDate":"1996","journal":"Biochem. J.","firstPage":"99","lastPage":"102","volume":"319"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]","PROTEIN SEQUENCE OF 1-20 AND 283-296"],"referenceComments":[{"value":"NBRC 3781","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"9427736","citationType":"journal article","authors":["Medrano F.J.","Alonso J.","Garcia J.L.","Romero A.","Bode W.","Gomis-Ruth F.X."],"citationCrossReferences":[{"database":"PubMed","id":"9427736"},{"database":"DOI","id":"10.1093/emboj/17.1.1"}],"title":"Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: a prototype for the prolyl oligopeptidase family.","publicationDate":"1998","journal":"EMBO J.","firstPage":"1","lastPage":"9","volume":"17"},"referencePositions":["X-RAY CRYSTALLOGRAPHY","ACTIVE SITE"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"Z54150","properties":[{"key":"ProteinId","value":"CAA90864.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"D82882","properties":[{"key":"ProteinId","value":"BAA11623.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PDB","id":"1AZW","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"2.70 A"},{"key":"Chains","value":"A/B=1-313"}]},{"database":"AlphaFoldDB","id":"P52279","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P52279","properties":[{"key":"Description","value":"-"}]},{"database":"ESTHER","id":"xanca-impep","properties":[{"key":"FamilyName","value":"Proline_iminopeptidase"}]},{"database":"MEROPS","id":"S33.001","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"AACRYWA","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"EvolutionaryTrace","id":"P52279","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0004177","properties":[{"key":"GoTerm","value":"F:aminopeptidase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0006508","properties":[{"key":"GoTerm","value":"P:proteolysis"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.40.50.1820","properties":[{"key":"EntryName","value":"alpha/beta hydrolase"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR000073","properties":[{"key":"EntryName","value":"AB_hydrolase_1"}]},{"database":"InterPro","id":"IPR029058","properties":[{"key":"EntryName","value":"AB_hydrolase_fold"}]},{"database":"InterPro","id":"IPR002410","properties":[{"key":"EntryName","value":"Peptidase_S33"}]},{"database":"InterPro","id":"IPR005944","properties":[{"key":"EntryName","value":"Pro_iminopeptidase"}]},{"database":"NCBIfam","id":"TIGR01249","properties":[{"key":"EntryName","value":"pro_imino_pep_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR43722","properties":[{"key":"EntryName","value":"PROLINE IMINOPEPTIDASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR43722:SF1","properties":[{"key":"EntryName","value":"PROLINE IMINOPEPTIDASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00561","properties":[{"key":"EntryName","value":"Abhydrolase_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF006431","properties":[{"key":"EntryName","value":"Pept_S33"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00793","properties":[{"key":"EntryName","value":"PROAMNOPTASE"}]},{"database":"SUPFAM","id":"SSF53474","properties":[{"key":"EntryName","value":"alpha/beta-Hydrolases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MRTLYPEITPYQQGSLKVDDRHTLYFEQCGNPHGKPVVMLHGGPGGGCNDKMRRFHDPAKYRIVLFDQRGSGRSTPHADLVDNTTWDLVADIERLRTHLGVDRWQVFGGSWGSTLALAYAADPSAAGHQLVLRGIFLLRRFELEWFYQEGASRLFPDAWEHYLNAIPPVERADLMSAFHRRLTSDDEATRLAAAKAWSVWEGATSFLHVDEDFVTGHEDAHFALAFARIENHYFVNGGFFEVEDQLLRDAHRIADIPGVIVHGRYDVVCPLQSAWDLHKAWPKAQLQISPASGHSAFEPENVDALVRATDGFA","length":313,"molWeight":35260,"crc64":"7A9DF2636363FF48","md5":"7FB874AE52C0D0FB092CC5EE53F1E3F5"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Domain":1,"Active site":3,"Sequence conflict":4,"Helix":18,"Beta strand":12,"Turn":2},"uniParcId":"UPI0000131B12"}},{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P60512","secondaryAccessions":["O86050"],"uniProtkbId":"LEXA_XANCI","entryAudit":{"firstPublicDate":"2004-03-01","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2004-03-01","entryVersion":99,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00015"}],"value":"LexA repressor"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00015"}],"value":"3.4.21.88"}]}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00015"}],"value":"lexA"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Has been shown to bind to the palindromic sequence 5'-CTG-N(8-12)-C-[TC]-G. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"Hydrolysis of Ala-|-Gly bond in repressor LexA.","ecNumber":"3.4.21.88","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00015"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00015"}],"value":"Homodimer"}],"commentType":"SUBUNIT"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00015"}],"value":"Belongs to the peptidase S24 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":213,"modifier":"EXACT"}},"description":"LexA repressor","featureId":"PRO_0000170108"},{"type":"DNA binding","location":{"start":{"value":27,"modifier":"EXACT"},"end":{"value":47,"modifier":"EXACT"}},"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00015"}]},{"type":"Active site","location":{"start":{"value":133,"modifier":"EXACT"},"end":{"value":133,"modifier":"EXACT"}},"description":"For autocatalytic cleavage activity","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00015"}]},{"type":"Active site","location":{"start":{"value":170,"modifier":"EXACT"},"end":{"value":170,"modifier":"EXACT"}},"description":"For autocatalytic cleavage activity","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00015"}]},{"type":"Site","location":{"start":{"value":98,"modifier":"EXACT"},"end":{"value":99,"modifier":"EXACT"}},"description":"Cleavage; by autolysis","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00015"}]}],"keywords":[{"id":"KW-0068","category":"PTM","name":"Autocatalytic cleavage"},{"id":"KW-0227","category":"Biological process","name":"DNA damage"},{"id":"KW-0234","category":"Biological process","name":"DNA repair"},{"id":"KW-0235","category":"Biological process","name":"DNA replication"},{"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"id":"KW-0678","category":"Molecular function","name":"Repressor"},{"id":"KW-0742","category":"Biological process","name":"SOS response"},{"id":"KW-0804","category":"Biological process","name":"Transcription"},{"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"10688691","citationType":"journal article","authors":["Yang M.-K.","Wu P.-I.","Yang Y.-C."],"citationCrossReferences":[{"database":"PubMed","id":"10688691"},{"database":"DOI","id":"10.1007/s002849910047"}],"title":"Identification of a lexA gene in, and construction of a lexA mutant of, Xanthomonas campestris pv. citri.","publicationDate":"2000","journal":"Curr. Microbiol.","firstPage":"233","lastPage":"238","volume":"40"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]","DNA-BINDING SPECIFICITY"],"referenceComments":[{"value":"XW47","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AF081945","properties":[{"key":"ProteinId","value":"AAC31950.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_005915033.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP059992.1"}]},{"database":"AlphaFoldDB","id":"P60512","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P60512","properties":[{"key":"Description","value":"-"}]},{"database":"MEROPS","id":"S24.001","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"66910889","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0032993","properties":[{"key":"GoTerm","value":"C:protein-DNA complex"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0001217","properties":[{"key":"GoTerm","value":"F:DNA-binding transcription repressor activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0004252","properties":[{"key":"GoTerm","value":"F:serine-type endopeptidase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0000976","properties":[{"key":"GoTerm","value":"F:transcription cis-regulatory region binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0006281","properties":[{"key":"GoTerm","value":"P:DNA repair"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0006260","properties":[{"key":"GoTerm","value":"P:DNA replication"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0006508","properties":[{"key":"GoTerm","value":"P:proteolysis"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009432","properties":[{"key":"GoTerm","value":"P:SOS response"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"CDD","id":"cd06529","properties":[{"key":"EntryName","value":"S24_LexA-like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.10.10:FF:000009","properties":[{"key":"EntryName","value":"LexA repressor"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.10.109.10:FF:000001","properties":[{"key":"EntryName","value":"LexA repressor"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.10.109.10","properties":[{"key":"EntryName","value":"Umud Fragment, subunit A"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.10.10","properties":[{"key":"EntryName","value":"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"HAMAP","id":"MF_00015","properties":[{"key":"EntryName","value":"LexA"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR006200","properties":[{"key":"EntryName","value":"LexA"}]},{"database":"InterPro","id":"IPR039418","properties":[{"key":"EntryName","value":"LexA-like"}]},{"database":"InterPro","id":"IPR036286","properties":[{"key":"EntryName","value":"LexA/Signal_pep-like_sf"}]},{"database":"InterPro","id":"IPR006199","properties":[{"key":"EntryName","value":"LexA_DNA-bd_dom"}]},{"database":"InterPro","id":"IPR050077","properties":[{"key":"EntryName","value":"LexA_repressor"}]},{"database":"InterPro","id":"IPR006197","properties":[{"key":"EntryName","value":"Peptidase_S24_LexA"}]},{"database":"InterPro","id":"IPR015927","properties":[{"key":"EntryName","value":"Peptidase_S24_S26A/B/C"}]},{"database":"InterPro","id":"IPR036388","properties":[{"key":"EntryName","value":"WH-like_DNA-bd_sf"}]},{"database":"InterPro","id":"IPR036390","properties":[{"key":"EntryName","value":"WH_DNA-bd_sf"}]},{"database":"NCBIfam","id":"TIGR00498","properties":[{"key":"EntryName","value":"lexA"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33516","properties":[{"key":"EntryName","value":"LEXA REPRESSOR"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33516:SF2","properties":[{"key":"EntryName","value":"LEXA REPRESSOR-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01726","properties":[{"key":"EntryName","value":"LexA_DNA_bind"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00717","properties":[{"key":"EntryName","value":"Peptidase_S24"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00726","properties":[{"key":"EntryName","value":"LEXASERPTASE"}]},{"database":"SUPFAM","id":"SSF51306","properties":[{"key":"EntryName","value":"LexA/Signal peptidase"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF46785","properties":[{"key":"EntryName","value":"Winged helix' DNA-binding domain"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDLTDTQQAILALIAERIDADGVPPSQTEIARAFGFKGIRAAQYHLEALEHAGAIRRVPGQARGIRLAGQGAQTRTAPVSEVARDDVLRLPVLGRVAAGLPIGADIGSDDFVVLDRVFFSPSPDYLLKVQGDSMRDEGIFNGDLIGVHRTRDARSGQIVVARIDEEITVKLLKIGKDRIRLLPRNPDYAPIEVLPDQDFAIEGLYCGLLRPNR","length":213,"molWeight":23240,"crc64":"30C56E5396EAF946","md5":"4851F8E88910FF8BBE5B4453508A2F33"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"SUBUNIT":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"DNA binding":1,"Active site":2,"Site":1},"uniParcId":"UPI000012E5CD"}},{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P0A0W5","secondaryAccessions":["O34257"],"uniProtkbId":"RECA_XANCI","entryAudit":{"firstPublicDate":"2005-02-15","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2005-02-15","entryVersion":79,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00268"}],"value":"Protein RecA"}},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00268"}],"value":"Recombinase A"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00268"}],"value":"recA"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00268"}],"value":"Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage"}],"commentType":"FUNCTION"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00268"}],"value":"Cytoplasm","id":"SL-0086"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00268"}],"value":"Belongs to the RecA family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":344,"modifier":"EXACT"}},"description":"Protein RecA","featureId":"PRO_0000122902"},{"type":"Region","location":{"start":{"value":323,"modifier":"EXACT"},"end":{"value":344,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":323,"modifier":"EXACT"},"end":{"value":337,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Binding site","location":{"start":{"value":65,"modifier":"EXACT"},"end":{"value":72,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00268"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0227","category":"Biological process","name":"DNA damage"},{"id":"KW-0233","category":"Biological process","name":"DNA recombination"},{"id":"KW-0234","category":"Biological process","name":"DNA repair"},{"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"id":"KW-0742","category":"Biological process","name":"SOS response"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-6ES8NPPR2JO3K","citationType":"submission","authors":["Yang M.-K.","Yang Y.-C."],"publicationDate":"JUN-1997","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"XW47","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AF006590","properties":[{"key":"ProteinId","value":"AAB63678.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_011051113.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP059992.1"}]},{"database":"AlphaFoldDB","id":"P0A0W5","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P0A0W5","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"66910890","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"AAECQKS","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0140664","properties":[{"key":"GoTerm","value":"F:ATP-dependent DNA damage sensor activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0003684","properties":[{"key":"GoTerm","value":"F:damaged DNA binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0003697","properties":[{"key":"GoTerm","value":"F:single-stranded DNA binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0006310","properties":[{"key":"GoTerm","value":"P:DNA recombination"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0006281","properties":[{"key":"GoTerm","value":"P:DNA repair"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0009432","properties":[{"key":"GoTerm","value":"P:SOS response"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"CDD","id":"cd00983","properties":[{"key":"EntryName","value":"RecA"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.40.50.300:FF:000087","properties":[{"key":"EntryName","value":"Recombinase RecA"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.300","properties":[{"key":"EntryName","value":"P-loop containing nucleotide triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"HAMAP","id":"MF_00268","properties":[{"key":"EntryName","value":"RecA"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003593","properties":[{"key":"EntryName","value":"AAA+_ATPase"}]},{"database":"InterPro","id":"IPR013765","properties":[{"key":"EntryName","value":"DNA_recomb/repair_RecA"}]},{"database":"InterPro","id":"IPR020584","properties":[{"key":"EntryName","value":"DNA_recomb/repair_RecA_CS"}]},{"database":"InterPro","id":"IPR027417","properties":[{"key":"EntryName","value":"P-loop_NTPase"}]},{"database":"InterPro","id":"IPR049261","properties":[{"key":"EntryName","value":"RecA-like_C"}]},{"database":"InterPro","id":"IPR049428","properties":[{"key":"EntryName","value":"RecA-like_N"}]},{"database":"InterPro","id":"IPR020588","properties":[{"key":"EntryName","value":"RecA_ATP-bd"}]},{"database":"InterPro","id":"IPR023400","properties":[{"key":"EntryName","value":"RecA_C_sf"}]},{"database":"InterPro","id":"IPR020587","properties":[{"key":"EntryName","value":"RecA_monomer-monomer_interface"}]},{"database":"NCBIfam","id":"TIGR02012","properties":[{"key":"EntryName","value":"tigrfam_recA"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR45900:SF1","properties":[{"key":"EntryName","value":"MITOCHONDRIAL DNA REPAIR PROTEIN RECA HOMOLOG-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR45900","properties":[{"key":"EntryName","value":"RECA"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF21096","properties":[{"key":"EntryName","value":"RecA_C"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00154","properties":[{"key":"EntryName","value":"RecA_N"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00142","properties":[{"key":"EntryName","value":"RECA"}]},{"database":"SMART","id":"SM00382","properties":[{"key":"EntryName","value":"AAA"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52540","properties":[{"key":"EntryName","value":"P-loop containing nucleoside triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF54752","properties":[{"key":"EntryName","value":"RecA protein, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00321","properties":[{"key":"EntryName","value":"RECA_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50162","properties":[{"key":"EntryName","value":"RECA_2"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50163","properties":[{"key":"EntryName","value":"RECA_3"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDENKKRALSAALSQIEKQFGKGSVMRMGDRVIEAVEVIPTGSLMLDIALGIGGLPKGRVVEIYGPESSGKTTLTLQAIAECQKNGGTAAFIDAEHALDPIYAAKLGVNVDDLLLSQPDTGEQALEIADMLVRSGSVDIVVVDSVAALTPKAEIEGEMGDQLPGLQARLMSQALRKLTGNIKRSNTLVVFINQLRMKIGVMMPGQSPEVTTGGNALKFYASVRLDIRRIGAIKKGDEIIGNQTKIKVVKNKLAPPFKQVVTEILYGEGISREGELIDMGVEAKLVDKAGAWYSYGDERIGQGKDNARTYLRDNSQVATRLEAELREKFQPAEAPREAGDDEDKE","length":344,"molWeight":37167,"crc64":"430F35A2155D9BD6","md5":"E5969371F2DDD3B641F1718FEA4612CF"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Region":1,"Compositional bias":1,"Binding site":1},"uniParcId":"UPI0000133546"}},{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P0A0W7","secondaryAccessions":["Q9LCZ3"],"uniProtkbId":"RECX_XANCI","entryAudit":{"firstPublicDate":"2005-02-15","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2005-02-15","entryVersion":53,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"value":"Regulatory protein RecX"}}},"genes":[{"geneName":{"value":"recX"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Modulates RecA activity"}],"commentType":"FUNCTION"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Cytoplasm","id":"SL-0086"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the RecX family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":162,"modifier":"EXACT"}},"description":"Regulatory protein RecX","featureId":"PRO_0000162496"}],"keywords":[{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"}],"references":[{"referenceNumber":1,"citation":{"id":"11178726","citationType":"journal article","authors":["Yang M.-K.","Chou M.-E.","Yang Y.-C."],"citationCrossReferences":[{"database":"PubMed","id":"11178726"},{"database":"DOI","id":"10.1007/s002840110214"}],"title":"Molecular characterization and expression of the recX gene of Xanthomonas campestris pv. citri.","publicationDate":"2001","journal":"Curr. Microbiol.","firstPage":"257","lastPage":"263","volume":"42"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"XW47","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AF006590","properties":[{"key":"ProteinId","value":"AAF65178.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_003481873.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CAVLIF010000058.1"}]},{"database":"AlphaFoldDB","id":"P0A0W7","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P0A0W7","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"66910891","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0006282","properties":[{"key":"GoTerm","value":"P:regulation of DNA repair"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"Gene3D","id":"1.10.10.10","properties":[{"key":"EntryName","value":"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"},{"key":"MatchStatus","value":"3"}]},{"database":"HAMAP","id":"MF_01114","properties":[{"key":"EntryName","value":"RecX"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR053926","properties":[{"key":"EntryName","value":"RecX_HTH_1st"}]},{"database":"InterPro","id":"IPR053924","properties":[{"key":"EntryName","value":"RecX_HTH_2nd"}]},{"database":"InterPro","id":"IPR053925","properties":[{"key":"EntryName","value":"RecX_HTH_3rd"}]},{"database":"InterPro","id":"IPR003783","properties":[{"key":"EntryName","value":"Regulatory_RecX"}]},{"database":"InterPro","id":"IPR036388","properties":[{"key":"EntryName","value":"WH-like_DNA-bd_sf"}]},{"database":"NCBIfam","id":"NF001054","properties":[{"key":"EntryName","value":"recX"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33602","properties":[{"key":"EntryName","value":"REGULATORY PROTEIN RECX FAMILY PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33602:SF1","properties":[{"key":"EntryName","value":"REGULATORY PROTEIN RECX FAMILY PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF21982","properties":[{"key":"EntryName","value":"RecX_HTH1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02631","properties":[{"key":"EntryName","value":"RecX_HTH2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF21981","properties":[{"key":"EntryName","value":"RecX_HTH3"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDEQEPAPKRGRRFKEQTPVQRALGLLVRREHSRKELNRKLLARGIEPDAAQAAVDRLTDEGWQDDTRFAAAVVRNRAGSGYGPLHIRAELGTHGLDSEAISAALAAFEGDWTENARDLIRRRFGEQGPTDLPQRRKAADLLARRGFEGNSIRAATRFDLED","length":162,"molWeight":18154,"crc64":"31B28244A0C4BA06","md5":"8AB874D7F47F6154B9BA44279C15ACE5"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1},"uniParcId":"UPI000013361E"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q670P6","uniProtkbId":"Q670P6_XANCI","entryAudit":{"firstPublicDate":"2004-10-11","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2004-10-11","entryVersion":96,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAU05602.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00019965"},{"evidenceCode":"ECO:0000256","source":"NCBIfam","id":"TIGR01816"}],"value":"Succinate dehydrogenase flavoprotein subunit"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012792"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"value":"1.3.5.1"}]}},"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"a quinone + succinate = fumarate + a quinol","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:40523"},{"database":"ChEBI","id":"CHEBI:24646"},{"database":"ChEBI","id":"CHEBI:29806"},{"database":"ChEBI","id":"CHEBI:30031"},{"database":"ChEBI","id":"CHEBI:132124"}],"ecNumber":"1.3.5.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00049220"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"FAD","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-3"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:57692"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-3"}],"value":"Flavinylated by SdhE, about 5% flavinylation occurs in the absence of SdhE."}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004894"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"value":"Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (bacterial route): step 1/1"}],"commentType":"PATHWAY"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004515"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"value":"Cell inner membrane","id":"SL-0037"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004515"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"value":"Peripheral membrane protein","id":"SL-9903"},"orientation":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004515"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"value":"Cytoplasmic side","id":"SL-9910"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00008040"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"value":"Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":12,"modifier":"EXACT"},"end":{"value":408,"modifier":"EXACT"}},"description":"FAD-dependent oxidoreductase 2 FAD-binding","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF00890"}]},{"type":"Domain","location":{"start":{"value":463,"modifier":"EXACT"},"end":{"value":596,"modifier":"EXACT"}},"description":"Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF02910"}]},{"type":"Active site","location":{"start":{"value":290,"modifier":"EXACT"},"end":{"value":290,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000171-1"}]},{"type":"Binding site","location":{"start":{"value":17,"modifier":"EXACT"},"end":{"value":22,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:57692"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-3"}],"ligand":{"name":"FAD","id":"ChEBI:CHEBI:57692"}},{"type":"Binding site","location":{"start":{"value":40,"modifier":"EXACT"},"end":{"value":55,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:57692"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-3"}],"ligand":{"name":"FAD","id":"ChEBI:CHEBI:57692"}},{"type":"Binding site","location":{"start":{"value":225,"modifier":"EXACT"},"end":{"value":225,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:57692"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-3"}],"ligand":{"name":"FAD","id":"ChEBI:CHEBI:57692"}},{"type":"Binding site","location":{"start":{"value":246,"modifier":"EXACT"},"end":{"value":246,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-2"}],"ligand":{"name":"substrate"}},{"type":"Binding site","location":{"start":{"value":258,"modifier":"EXACT"},"end":{"value":258,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-2"}],"ligand":{"name":"substrate"}},{"type":"Binding site","location":{"start":{"value":357,"modifier":"EXACT"},"end":{"value":357,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-2"}],"ligand":{"name":"substrate"}},{"type":"Binding site","location":{"start":{"value":391,"modifier":"EXACT"},"end":{"value":391,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:57692"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-3"}],"ligand":{"name":"FAD","id":"ChEBI:CHEBI:57692"}},{"type":"Binding site","location":{"start":{"value":402,"modifier":"EXACT"},"end":{"value":402,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-2"}],"ligand":{"name":"substrate"}},{"type":"Binding site","location":{"start":{"value":407,"modifier":"EXACT"},"end":{"value":408,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:57692"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-3"}],"ligand":{"name":"FAD","id":"ChEBI:CHEBI:57692"}},{"type":"Modified residue","location":{"start":{"value":48,"modifier":"EXACT"},"end":{"value":48,"modifier":"EXACT"}},"description":"Tele-8alpha-FAD histidine","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-4"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"id":"KW-0997","category":"Cellular component","name":"Cell inner membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022982"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"id":"KW-0249","category":"Biological process","name":"Electron transport"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022827"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-3"}],"id":"KW-0274","category":"Ligand","name":"FAD"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022630"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR611281-3"}],"id":"KW-0285","category":"Ligand","name":"Flavoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022448"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"id":"KW-0813","category":"Biological process","name":"Transport"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022532"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362051"}],"id":"KW-0816","category":"Biological process","name":"Tricarboxylic acid cycle"}],"references":[{"referenceNumber":1,"citation":{"id":"16602085","citationType":"journal article","authors":["Li J.","Zhou M.","Li H.","Chen C.","Wang J.","Zhang Y."],"citationCrossReferences":[{"database":"PubMed","id":"16602085"},{"database":"DOI","id":"10.1002/ps.1187"}],"title":"A study on the molecular mechanism of resistance to amicarthiazol in Xanthomonas campestris pv. citri.","publicationDate":"2006","journal":"Pest Manag. Sci.","firstPage":"440","lastPage":"445","volume":"62"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAU05602.1"}],"value":"Xcc","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAU05602.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY695406","properties":[{"key":"ProteinId","value":"AAU05602.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_011051316.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP059992.1"}]},{"database":"AlphaFoldDB","id":"Q670P6","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"66911211","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"AAEHIMG","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"UniPathway","id":"UPA00223","properties":[{"key":"RectionId","value":"UER01005"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0009055","properties":[{"key":"GoTerm","value":"F:electron transfer activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0050660","properties":[{"key":"GoTerm","value":"F:flavin adenine dinucleotide binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0008177","properties":[{"key":"GoTerm","value":"F:succinate dehydrogenase (quinone) activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0009061","properties":[{"key":"GoTerm","value":"P:anaerobic respiration"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0022900","properties":[{"key":"GoTerm","value":"P:electron transport chain"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0006099","properties":[{"key":"GoTerm","value":"P:tricarboxylic acid cycle"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"FunFam","id":"4.10.80.40:FF:000002","properties":[{"key":"EntryName","value":"Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.50.50.60:FF:000026","properties":[{"key":"EntryName","value":"Succinate dehydrogenase flavoprotein subunit"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.20.58.100:FF:000001","properties":[{"key":"EntryName","value":"Succinate dehydrogenase flavoprotein subunit (SdhA)"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.50.50.60","properties":[{"key":"EntryName","value":"FAD/NAD(P)-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.58.100","properties":[{"key":"EntryName","value":"Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"4.10.80.40","properties":[{"key":"EntryName","value":"succinate dehydrogenase protein domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.90.700.10","properties":[{"key":"EntryName","value":"Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003953","properties":[{"key":"EntryName","value":"FAD-dep_OxRdtase_2_FAD-bd"}]},{"database":"InterPro","id":"IPR036188","properties":[{"key":"EntryName","value":"FAD/NAD-bd_sf"}]},{"database":"InterPro","id":"IPR003952","properties":[{"key":"EntryName","value":"FRD_SDH_FAD_BS"}]},{"database":"InterPro","id":"IPR037099","properties":[{"key":"EntryName","value":"Fum_R/Succ_DH_flav-like_C_sf"}]},{"database":"InterPro","id":"IPR015939","properties":[{"key":"EntryName","value":"Fum_Rdtase/Succ_DH_flav-like_C"}]},{"database":"InterPro","id":"IPR030664","properties":[{"key":"EntryName","value":"SdhA/FrdA/AprA"}]},{"database":"InterPro","id":"IPR027477","properties":[{"key":"EntryName","value":"Succ_DH/fumarate_Rdtase_cat_sf"}]},{"database":"InterPro","id":"IPR011281","properties":[{"key":"EntryName","value":"Succ_DH_flav_su_fwd"}]},{"database":"InterPro","id":"IPR014006","properties":[{"key":"EntryName","value":"Succ_Dhase_FrdA_Gneg"}]},{"database":"NCBIfam","id":"TIGR01816","properties":[{"key":"EntryName","value":"sdhA_forward"},{"key":"MatchStatus","value":"1"}]},{"database":"NCBIfam","id":"TIGR01812","properties":[{"key":"EntryName","value":"sdhA_frdA_Gneg"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11632","properties":[{"key":"EntryName","value":"SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11632:SF51","properties":[{"key":"EntryName","value":"SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00890","properties":[{"key":"EntryName","value":"FAD_binding_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02910","properties":[{"key":"EntryName","value":"Succ_DH_flav_C"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF000171","properties":[{"key":"EntryName","value":"SDHA_APRA_LASPO"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF51905","properties":[{"key":"EntryName","value":"FAD/NAD(P)-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF46977","properties":[{"key":"EntryName","value":"Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56425","properties":[{"key":"EntryName","value":"Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00504","properties":[{"key":"EntryName","value":"FRD_SDH_FAD_BINDING"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSAYKITEHKYDMVVVGAGGAGLRATFGLAQKGLQTVCLTKVFPTRSHTVAAQGGISAALGNMGEDDWRYHFYDTIKGSDWLGDQDAIEYMCREAIPAIIELEHYGVPFSRTEEGKIYQRPFGGMTTKYGEGPSAQRTCAAADRTGHAMLHTLYQQSLAHNARFMIEYFALDLIFDEEGVCRGVLALDMAEGSLHLFRAHGVVLATGGYGRAYFSATSAHTCTGDGGGLVMRAGLPVQDMEFVQFHPTGIYGAGCLITEGVRGEGGILRNSNGERFMERYAPHYKDLASRDVVSRSMTVEIREGRGVGEHKDHILLDLTHLGPEVINEKLPGIAESAHIFAGVDVTKQPIPVLPTVHYNMGGIPTNFYGEVVRKRGDDADAVVPGLYAIGEAACVSVHGANRLGSNSLLDLVVFGRAVANRCAETVKPNQPHKTLPSDACDKALGLLDKLRHANGSTPTAVIRDNMQRTMQSDAAVFRTSKTLKEGVDKMAEIFATFEDVKVSDRSLVWNSDLIETYELNNLLLNAVATINSAEQRKESRGAHSHEDFPDRDDVNWQKHTLVTVDDKGKCEFDYRPVHMYTLSKDVDVVPPKPRVY","length":596,"molWeight":65299,"crc64":"A78E82D66F3AA81F","md5":"15588C9C4F4723803CEE82B430BFC855"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"COFACTOR":1,"PATHWAY":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Domain":2,"Active site":1,"Binding site":9,"Modified residue":1},"uniParcId":"UPI00000D8031"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"O52613","uniProtkbId":"O52613_XANCI","entryAudit":{"firstPublicDate":"1998-06-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1998-06-01","entryVersion":83,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAB97527.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAB97527.1"}],"value":"Fimbrillin"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAB97527.1"}],"value":"fimA"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00005233"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000389"}],"value":"Belongs to the N-Me-Phe pilin family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01070"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Propeptide","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":6,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01070"}],"featureId":"PRO_5048704007"},{"type":"Chain","location":{"start":{"value":7,"modifier":"EXACT"},"end":{"value":146,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01070"}],"featureId":"PRO_5048704006"},{"type":"Transmembrane","location":{"start":{"value":7,"modifier":"EXACT"},"end":{"value":27,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Modified residue","location":{"start":{"value":7,"modifier":"EXACT"},"end":{"value":7,"modifier":"EXACT"}},"description":"N-methylphenylalanine","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01070"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000389"}],"id":"KW-0281","category":"Cellular component","name":"Fimbrium"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022481"}],"id":"KW-0488","category":"PTM","name":"Methylation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"10503532","citationType":"journal article","authors":["Su W.C.","Tung S.Y.","Yang M.K.","Kuo T.T."],"citationCrossReferences":[{"database":"PubMed","id":"10503532"},{"database":"DOI","id":"10.1007/s004380051055"}],"title":"The pilA gene of Xanthomonas campestris pv. citri is required for infection by the filamentous phage cf.","publicationDate":"1999","journal":"Mol. Gen. Genet.","firstPage":"22","lastPage":"26","volume":"262"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAB97527.1"}],"value":"XW47","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAB97527.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AF042829","properties":[{"key":"ProteinId","value":"AAB97527.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"O52613","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0044096","properties":[{"key":"GoTerm","value":"C:type IV pilus"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0007155","properties":[{"key":"GoTerm","value":"P:cell adhesion"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0043107","properties":[{"key":"GoTerm","value":"P:type IV pilus-dependent motility"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"Gene3D","id":"3.30.700.10","properties":[{"key":"EntryName","value":"Glycoprotein, Type 4 Pilin"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR012902","properties":[{"key":"EntryName","value":"N_methyl_site"}]},{"database":"InterPro","id":"IPR001082","properties":[{"key":"EntryName","value":"Pilin"}]},{"database":"InterPro","id":"IPR045584","properties":[{"key":"EntryName","value":"Pilin-like"}]},{"database":"NCBIfam","id":"TIGR02532","properties":[{"key":"EntryName","value":"IV_pilin_GFxxxE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30093","properties":[{"key":"EntryName","value":"GENERAL SECRETION PATHWAY PROTEIN G"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30093:SF34","properties":[{"key":"EntryName","value":"PREPILIN PEPTIDASE-DEPENDENT PROTEIN D"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07963","properties":[{"key":"EntryName","value":"N_methyl"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00114","properties":[{"key":"EntryName","value":"Pilin"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF54523","properties":[{"key":"EntryName","value":"Pili subunits"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00409","properties":[{"key":"EntryName","value":"PROKAR_NTER_METHYL"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKKQQGFTLIELMIVIAIIAILAAIALPQYQNYVAKSQVTAGLAELSPGKTQYETLLNEGKGTTLTTADAVGLQATSTTNRCSAITVLAPDATAGEQTNALSCTLAGSPRIVGKKITWARDTNGVWTCSTDIATADKAKFAPATCQ","length":146,"molWeight":15250,"crc64":"6D0C7F3C1E824DAE","md5":"1BB6936DE1E44A8226007072DE4E4FF8"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1,"CAUTION":1},"countByFeatureType":{"Propeptide":1,"Chain":1,"Transmembrane":1,"Modified residue":1},"uniParcId":"UPI00000B0F73"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q6B4H3","uniProtkbId":"Q6B4H3_XANCI","entryAudit":{"firstPublicDate":"2004-09-13","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2004-09-13","entryVersion":60,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91479.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00019425"}],"value":"Succinate dehydrogenase hydrophobic membrane anchor subunit"}}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91479.1"}],"value":"sdhD"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004050"}],"value":"Membrane-anchoring subunit of succinate dehydrogenase (SDH)"}],"commentType":"FUNCTION"},{"commentType":"COFACTOR","cofactors":[{"name":"heme","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001971"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:30413"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00005163"}],"value":"Carbohydrate metabolism; tricarboxylic acid cycle"}],"commentType":"PATHWAY"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004651"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004651"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]}],"features":[{"type":"Transmembrane","location":{"start":{"value":29,"modifier":"EXACT"},"end":{"value":51,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":63,"modifier":"EXACT"},"end":{"value":84,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":104,"modifier":"EXACT"},"end":{"value":125,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022982"}],"id":"KW-0249","category":"Biological process","name":"Electron transport"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022617"}],"id":"KW-0349","category":"Ligand","name":"Heme"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022448"}],"id":"KW-0813","category":"Biological process","name":"Transport"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022532"}],"id":"KW-0816","category":"Biological process","name":"Tricarboxylic acid cycle"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-EHJHTDSSFAN5T","citationType":"submission","authors":["Jun L.","Mingguo Z."],"title":"Cloning of Xanthomonas campestris pv. citri succinate dehydrogenase gene.","publicationDate":"JUL-2004","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91479.1"}]},{"referenceNumber":2,"citation":{"id":"16602085","citationType":"journal article","authors":["Li J.","Zhou M.","Li H.","Chen C.","Wang J.","Zhang Y."],"citationCrossReferences":[{"database":"PubMed","id":"16602085"},{"database":"DOI","id":"10.1002/ps.1187"}],"title":"A study on the molecular mechanism of resistance to amicarthiazol in Xanthomonas campestris pv. citri.","publicationDate":"2006","journal":"Pest Manag. Sci.","firstPage":"440","lastPage":"445","volume":"62"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91479.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY682986","properties":[{"key":"ProteinId","value":"AAT91479.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_011051315.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP059992.1"}]},{"database":"AlphaFoldDB","id":"Q6B4H3","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q6B4H3","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"66911210","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"AANHWMA","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"UniPathway","id":"UPA00223","properties":[{"key":"RectionId","value":"-"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0020037","properties":[{"key":"GoTerm","value":"F:heme binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006099","properties":[{"key":"GoTerm","value":"P:tricarboxylic acid cycle"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniPathway"}]},{"database":"CDD","id":"cd03495","properties":[{"key":"EntryName","value":"SQR_TypeC_SdhD_like"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.1300.10","properties":[{"key":"EntryName","value":"Fumarate reductase/succinate dehydrogenase, transmembrane subunit"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR034804","properties":[{"key":"EntryName","value":"SQR/QFR_C/D"}]},{"database":"InterPro","id":"IPR014312","properties":[{"key":"EntryName","value":"Succ_DH_anchor"}]},{"database":"InterPro","id":"IPR000701","properties":[{"key":"EntryName","value":"SuccDH_FuR_B_TM-su"}]},{"database":"NCBIfam","id":"TIGR02968","properties":[{"key":"EntryName","value":"succ_dehyd_anc"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR38689","properties":[{"key":"EntryName","value":"SUCCINATE DEHYDROGENASE HYDROPHOBIC MEMBRANE ANCHOR SUBUNIT"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR38689:SF1","properties":[{"key":"EntryName","value":"SUCCINATE DEHYDROGENASE HYDROPHOBIC MEMBRANE ANCHOR SUBUNIT"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01127","properties":[{"key":"EntryName","value":"Sdh_cyt"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF81343","properties":[{"key":"EntryName","value":"Fumarate reductase respiratory complex transmembrane subunits"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSRYRTPLKNVRGLGAAKTGTEHFVIQRLTAAALVPLSIWFLVFVLSLIGADHAAASAAVAKPWNAILLVAFLIASFWHAQLGMQVVLEDYVHDSLLALIAQTLVRFVAVLGAIVSVFAVARIALGMS","length":128,"molWeight":13710,"crc64":"A1D7CCB67B63BF48","md5":"7E25CC330FA73A73AFBF5C0CD5097774"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"COFACTOR":1,"PATHWAY":1,"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Transmembrane":3},"uniParcId":"UPI00000D8030"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q6B4H4","uniProtkbId":"Q6B4H4_XANCI","entryAudit":{"firstPublicDate":"2004-09-13","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2004-09-13","entryVersion":65,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91478.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00020076"}],"value":"Succinate dehydrogenase cytochrome b556 subunit"}}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91478.1"}],"value":"sdhC"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004050"}],"value":"Membrane-anchoring subunit of succinate dehydrogenase (SDH)"}],"commentType":"FUNCTION"},{"commentType":"COFACTOR","cofactors":[{"name":"heme","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000178-1"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:30413"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000178-1"}],"value":"The heme is bound between the two transmembrane subunits."}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00025912"}],"value":"Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004370"}],"value":"Membrane","id":"SL-0162"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00007244"}],"value":"Belongs to the cytochrome b560 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Transmembrane","location":{"start":{"value":25,"modifier":"EXACT"},"end":{"value":51,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":63,"modifier":"EXACT"},"end":{"value":84,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":105,"modifier":"EXACT"},"end":{"value":126,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Binding site","location":{"start":{"value":81,"modifier":"EXACT"},"end":{"value":81,"modifier":"EXACT"}},"description":"axial binding residue","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30413"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000178-1"}],"ligand":{"name":"heme","id":"ChEBI:CHEBI:30413","note":"ligand shared with second transmembrane subunit"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022617"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000178-1"}],"id":"KW-0349","category":"Ligand","name":"Heme"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000178-1"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000178-1"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-EHJHTDSSFAN5T","citationType":"submission","authors":["Jun L.","Mingguo Z."],"title":"Cloning of Xanthomonas campestris pv. citri succinate dehydrogenase gene.","publicationDate":"JUL-2004","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91478.1"}]},{"referenceNumber":2,"citation":{"id":"16602085","citationType":"journal article","authors":["Li J.","Zhou M.","Li H.","Chen C.","Wang J.","Zhang Y."],"citationCrossReferences":[{"database":"PubMed","id":"16602085"},{"database":"DOI","id":"10.1002/ps.1187"}],"title":"A study on the molecular mechanism of resistance to amicarthiazol in Xanthomonas campestris pv. citri.","publicationDate":"2006","journal":"Pest Manag. Sci.","firstPage":"440","lastPage":"445","volume":"62"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91478.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY682985","properties":[{"key":"ProteinId","value":"AAT91478.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_011051314.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP059992.1"}]},{"database":"AlphaFoldDB","id":"Q6B4H4","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q6B4H4","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"66911209","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"AANWMAR","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0009055","properties":[{"key":"GoTerm","value":"F:electron transfer activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006099","properties":[{"key":"GoTerm","value":"P:tricarboxylic acid cycle"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd03499","properties":[{"key":"EntryName","value":"SQR_TypeC_SdhC"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.20.1300.10:FF:000016","properties":[{"key":"EntryName","value":"Succinate dehydrogenase membrane anchor subunit"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.1300.10","properties":[{"key":"EntryName","value":"Fumarate reductase/succinate dehydrogenase, transmembrane subunit"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR034804","properties":[{"key":"EntryName","value":"SQR/QFR_C/D"}]},{"database":"InterPro","id":"IPR014314","properties":[{"key":"EntryName","value":"Succ_DH_cytb556"}]},{"database":"InterPro","id":"IPR000701","properties":[{"key":"EntryName","value":"SuccDH_FuR_B_TM-su"}]},{"database":"NCBIfam","id":"TIGR02970","properties":[{"key":"EntryName","value":"succ_dehyd_cytB"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10978","properties":[{"key":"EntryName","value":"SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10978:SF5","properties":[{"key":"EntryName","value":"SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01127","properties":[{"key":"EntryName","value":"Sdh_cyt"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF000178","properties":[{"key":"EntryName","value":"SDH_cyt_b560"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF81343","properties":[{"key":"EntryName","value":"Fumarate reductase respiratory complex transmembrane subunits"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MAIRERPLSPHLQVYRWQIQMVTSILNRATGIVLTVGALAIAAALLTLMLGPDHWNCFRAQAATWYGQVFLFGWTWSFAFHLFGGLRHMLQDFGQGYAVRSFISMGWLSVVLSLVLTAAIWAYVLLSGGAV","length":131,"molWeight":14587,"crc64":"D6C594DA9F52AC1E","md5":"94E7F597EEC5B0D6F2A29ADF678058C6"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"COFACTOR":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Transmembrane":3,"Binding site":1},"uniParcId":"UPI00000D802F"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q6B4H5","uniProtkbId":"Q6B4H5_XANCI","entryAudit":{"firstPublicDate":"2004-09-13","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2004-09-13","entryVersion":102,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91477.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022131"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"value":"Succinate dehydrogenase iron-sulfur subunit"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012792"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"value":"1.3.5.1"}]}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91477.1"}],"value":"sdhB"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"a quinone + succinate = fumarate + a quinol","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:40523"},{"database":"ChEBI","id":"CHEBI:24646"},{"database":"ChEBI","id":"CHEBI:29806"},{"database":"ChEBI","id":"CHEBI:30031"},{"database":"ChEBI","id":"CHEBI:132124"}],"ecNumber":"1.3.5.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00049220"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"[2Fe-2S] cluster","evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:190135"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"value":"Binds 1 [2Fe-2S] cluster."}]}},{"commentType":"COFACTOR","cofactors":[{"name":"[3Fe-4S] cluster","evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:21137"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"value":"Binds 1 [3Fe-4S] cluster."}]}},{"commentType":"COFACTOR","cofactors":[{"name":"[4Fe-4S] cluster","evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:49883"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"value":"Binds 1 [4Fe-4S] cluster."}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004894"}],"value":"Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (bacterial route): step 1/1"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00011294"}],"value":"Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein"}],"commentType":"SUBUNIT"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009433"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"value":"Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":36,"modifier":"EXACT"},"end":{"value":119,"modifier":"EXACT"}},"description":"2Fe-2S ferredoxin-type","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51085"}]},{"type":"Domain","location":{"start":{"value":161,"modifier":"EXACT"},"end":{"value":191,"modifier":"EXACT"}},"description":"4Fe-4S ferredoxin-type","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51379"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022714"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"id":"KW-0001","category":"Ligand","name":"2Fe-2S"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023291"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"id":"KW-0003","category":"Ligand","name":"3Fe-4S"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022485"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"id":"KW-0004","category":"Ligand","name":"4Fe-4S"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022982"}],"id":"KW-0249","category":"Biological process","name":"Electron transport"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023014"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"id":"KW-0411","category":"Ligand","name":"Iron-sulfur"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361237"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022448"}],"id":"KW-0813","category":"Biological process","name":"Transport"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022532"}],"id":"KW-0816","category":"Biological process","name":"Tricarboxylic acid cycle"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-EHJHTDSSFAN5T","citationType":"submission","authors":["Jun L.","Mingguo Z."],"title":"Cloning of Xanthomonas campestris pv. citri succinate dehydrogenase gene.","publicationDate":"JUL-2004","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91477.1"}]},{"referenceNumber":2,"citation":{"id":"16602085","citationType":"journal article","authors":["Li J.","Zhou M.","Li H.","Chen C.","Wang J.","Zhang Y."],"citationCrossReferences":[{"database":"PubMed","id":"16602085"},{"database":"DOI","id":"10.1002/ps.1187"}],"title":"A study on the molecular mechanism of resistance to amicarthiazol in Xanthomonas campestris pv. citri.","publicationDate":"2006","journal":"Pest Manag. Sci.","firstPage":"440","lastPage":"445","volume":"62"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAT91477.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY682984","properties":[{"key":"ProteinId","value":"AAT91477.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_003482787.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CAVLIU010000109.1"}]},{"database":"AlphaFoldDB","id":"Q6B4H5","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q6B4H5","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"66911213","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"AACPAYW","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"GO","id":"GO:0051537","properties":[{"key":"GoTerm","value":"F:2 iron, 2 sulfur cluster binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009055","properties":[{"key":"GoTerm","value":"F:electron transfer activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0008177","properties":[{"key":"GoTerm","value":"F:succinate dehydrogenase (quinone) activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0022904","properties":[{"key":"GoTerm","value":"P:respiratory electron transport chain"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006099","properties":[{"key":"GoTerm","value":"P:tricarboxylic acid cycle"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"FunFam","id":"3.10.20.30:FF:000007","properties":[{"key":"EntryName","value":"Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.1060.10:FF:000001","properties":[{"key":"EntryName","value":"Succinate dehydrogenase iron-sulfur subunit SdhB"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.10.20.30","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.1060.10","properties":[{"key":"EntryName","value":"Alpha-helical ferredoxin"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR036010","properties":[{"key":"EntryName","value":"2Fe-2S_ferredoxin-like_sf"}]},{"database":"InterPro","id":"IPR001041","properties":[{"key":"EntryName","value":"2Fe-2S_ferredoxin-type"}]},{"database":"InterPro","id":"IPR006058","properties":[{"key":"EntryName","value":"2Fe2S_fd_BS"}]},{"database":"InterPro","id":"IPR017896","properties":[{"key":"EntryName","value":"4Fe4S_Fe-S-bd"}]},{"database":"InterPro","id":"IPR017900","properties":[{"key":"EntryName","value":"4Fe4S_Fe_S_CS"}]},{"database":"InterPro","id":"IPR012675","properties":[{"key":"EntryName","value":"Beta-grasp_dom_sf"}]},{"database":"InterPro","id":"IPR009051","properties":[{"key":"EntryName","value":"Helical_ferredxn"}]},{"database":"InterPro","id":"IPR050573","properties":[{"key":"EntryName","value":"SDH/FRD_Iron-Sulfur"}]},{"database":"InterPro","id":"IPR004489","properties":[{"key":"EntryName","value":"Succ_DH/fum_Rdtase_Fe-S"}]},{"database":"InterPro","id":"IPR025192","properties":[{"key":"EntryName","value":"Succ_DH/fum_Rdtase_N"}]},{"database":"NCBIfam","id":"TIGR00384","properties":[{"key":"EntryName","value":"dhsB"},{"key":"MatchStatus","value":"1"}]},{"database":"NCBIfam","id":"NF004616","properties":[{"key":"EntryName","value":"sdhB"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11921:SF29","properties":[{"key":"EntryName","value":"SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11921","properties":[{"key":"EntryName","value":"SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13085","properties":[{"key":"EntryName","value":"Fer2_3"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13534","properties":[{"key":"EntryName","value":"Fer4_17"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF54292","properties":[{"key":"EntryName","value":"2Fe-2S ferredoxin-like"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF46548","properties":[{"key":"EntryName","value":"alpha-helical ferredoxin"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00197","properties":[{"key":"EntryName","value":"2FE2S_FER_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51085","properties":[{"key":"EntryName","value":"2FE2S_FER_2"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00198","properties":[{"key":"EntryName","value":"4FE4S_FER_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51379","properties":[{"key":"EntryName","value":"4FE4S_FER_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MAEFTLPKNSKIGKGKHYPAKGAKNTRTFKVYRWDPDVDANPRTDSYEIDLDKCGPMVLDALIKIKNEIDPTLAFRRSCREGICGSCAMNIDGTNTLACTKAIAACGKSEVPIYPLPHMSVIKDLVPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPEDRRKLDGLYECILCACCSTSCPSYWWNGERYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPKGLNPALAIAEIKKLMMARRA","length":260,"molWeight":29396,"crc64":"3C4C915683C18290","md5":"F32AE35A73E782F08445721D8E6438E9"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"COFACTOR":3,"PATHWAY":1,"SUBUNIT":1,"SIMILARITY":1},"countByFeatureType":{"Domain":2},"uniParcId":"UPI00000D8032"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q6XL17","uniProtkbId":"Q6XL17_XANCI","entryAudit":{"firstPublicDate":"2004-07-05","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2004-07-05","entryVersion":100,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30659.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00039227"}],"value":"Leucine-responsive regulatory protein"}},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30659.1"}],"value":"lrp"}}],"features":[{"type":"Domain","location":{"start":{"value":8,"modifier":"EXACT"},"end":{"value":81,"modifier":"EXACT"}},"description":"HTH asnC-type","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50956"}]},{"type":"DNA binding","location":{"start":{"value":27,"modifier":"EXACT"},"end":{"value":46,"modifier":"EXACT"}},"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00319"}]},{"type":"Non-terminal residue","location":{"start":{"value":153,"modifier":"EXACT"},"end":{"value":153,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30659.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023159"}],"id":"KW-0010","category":"Molecular function","name":"Activator"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023125"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00319"}],"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023163"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00319"}],"id":"KW-0804","category":"Biological process","name":"Transcription"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023015"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00319"}],"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"15023955","citationType":"journal article","authors":["Cubero J.","Graham J.H."],"citationCrossReferences":[{"database":"PubMed","id":"15023955"},{"database":"DOI","id":"10.1099/ijs.0.02784-0"}],"title":"The leucine-responsive regulatory protein (lrp) gene for characterization of the relationship among Xanthomonas species.","publicationDate":"2004","journal":"Int. J. Syst. Evol. Microbiol.","firstPage":"429","lastPage":"437","volume":"54"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30658.1"}],"value":"CFBP 2852","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30661.1"}],"value":"JJ223.2","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30659.1"}],"value":"JK20.3","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30660.1"}],"value":"MA","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30662.1"}],"value":"MI","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30667.1"}],"value":"W1","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30668.1"}],"value":"X0052","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30664.1"}],"value":"X169","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30666.1"}],"value":"X205","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30663.1"}],"value":"X322","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30665.1"}],"value":"X406","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP30659.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY227401","properties":[{"key":"ProteinId","value":"AAP30658.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY227402","properties":[{"key":"ProteinId","value":"AAP30659.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY227403","properties":[{"key":"ProteinId","value":"AAP30660.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY227404","properties":[{"key":"ProteinId","value":"AAP30661.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY227405","properties":[{"key":"ProteinId","value":"AAP30662.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY227406","properties":[{"key":"ProteinId","value":"AAP30663.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY227407","properties":[{"key":"ProteinId","value":"AAP30664.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY227408","properties":[{"key":"ProteinId","value":"AAP30665.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY227409","properties":[{"key":"ProteinId","value":"AAP30666.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY227410","properties":[{"key":"ProteinId","value":"AAP30667.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY227411","properties":[{"key":"ProteinId","value":"AAP30668.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"Q6XL17","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0043565","properties":[{"key":"GoTerm","value":"F:sequence-specific DNA binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006351","properties":[{"key":"GoTerm","value":"P:DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0006355","properties":[{"key":"GoTerm","value":"P:regulation of DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0043201","properties":[{"key":"GoTerm","value":"P:response to L-leucine"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd00090","properties":[{"key":"EntryName","value":"HTH_ARSR"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.10.10:FF:000235","properties":[{"key":"EntryName","value":"AsnC family transcriptional regulator"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.70.920:FF:000001","properties":[{"key":"EntryName","value":"Transcriptional regulator, AsnC family"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.70.920","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.10.10","properties":[{"key":"EntryName","value":"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR011991","properties":[{"key":"EntryName","value":"ArsR-like_HTH"}]},{"database":"InterPro","id":"IPR000485","properties":[{"key":"EntryName","value":"AsnC-type_HTH_dom"}]},{"database":"InterPro","id":"IPR011008","properties":[{"key":"EntryName","value":"Dimeric_a/b-barrel"}]},{"database":"InterPro","id":"IPR019888","properties":[{"key":"EntryName","value":"Tscrpt_reg_AsnC-like"}]},{"database":"InterPro","id":"IPR019887","properties":[{"key":"EntryName","value":"Tscrpt_reg_AsnC/Lrp_C"}]},{"database":"InterPro","id":"IPR019885","properties":[{"key":"EntryName","value":"Tscrpt_reg_HTH_AsnC-type_CS"}]},{"database":"InterPro","id":"IPR036388","properties":[{"key":"EntryName","value":"WH-like_DNA-bd_sf"}]},{"database":"InterPro","id":"IPR036390","properties":[{"key":"EntryName","value":"WH_DNA-bd_sf"}]},{"database":"PANTHER","id":"PTHR30154","properties":[{"key":"EntryName","value":"LEUCINE-RESPONSIVE REGULATORY PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30154:SF0","properties":[{"key":"EntryName","value":"LEUCINE-RESPONSIVE REGULATORY PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01037","properties":[{"key":"EntryName","value":"AsnC_trans_reg"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13412","properties":[{"key":"EntryName","value":"HTH_24"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00033","properties":[{"key":"EntryName","value":"HTHASNC"}]},{"database":"SMART","id":"SM00344","properties":[{"key":"EntryName","value":"HTH_ASNC"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF54909","properties":[{"key":"EntryName","value":"Dimeric alpha+beta barrel"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF46785","properties":[{"key":"EntryName","value":"Winged helix' DNA-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00519","properties":[{"key":"EntryName","value":"HTH_ASNC_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50956","properties":[{"key":"EntryName","value":"HTH_ASNC_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSIRARELDKIDRKILRILQQEGRISFTELGERVGLSTTPCTERVRRLERDGAITGYYARLDPHYLKASLLVFVEISLAYKSGDIFEEFRRAALKLPNVLECHLVSGDFDYLLKARISEMASYRKLLGSTLLTMPHVRESKSYIVMEEVKETL","length":153,"molWeight":17656,"crc64":"A7D5D4D6C4243E18","md5":"B357B76B180A9C153FF775C9A584A7C3"},"extraAttributes":{"countByFeatureType":{"Domain":1,"DNA binding":1,"Non-terminal residue":1},"uniParcId":"UPI000023FF6A"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q7X3U2","uniProtkbId":"Q7X3U2_XANCI","entryAudit":{"firstPublicDate":"2003-10-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2003-10-01","entryVersion":103,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP55201.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012438"}],"value":"histidine kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012438"}],"value":"2.7.13.3"}]}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP55201.1"}],"value":"pilS"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.","ecNumber":"2.7.13.3","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00000085"}]}}],"features":[{"type":"Transmembrane","location":{"start":{"value":100,"modifier":"EXACT"},"end":{"value":122,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":134,"modifier":"EXACT"},"end":{"value":152,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":159,"modifier":"EXACT"},"end":{"value":178,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":184,"modifier":"EXACT"},"end":{"value":203,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":210,"modifier":"EXACT"},"end":{"value":228,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":240,"modifier":"EXACT"},"end":{"value":258,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Domain","location":{"start":{"value":403,"modifier":"EXACT"},"end":{"value":613,"modifier":"EXACT"}},"description":"Histidine kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50109"}]},{"type":"Modified residue","location":{"start":{"value":406,"modifier":"EXACT"},"end":{"value":406,"modifier":"EXACT"}},"description":"Phosphohistidine; by autocatalysis","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022553"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023012"}],"id":"KW-0902","category":"Biological process","name":"Two-component regulatory system"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-DL6TDM142IVTH","citationType":"submission","authors":["Kou T.T.","Yang Y.C.","Chou C.P.","Yang M.K."],"publicationDate":"MAY-2003","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP55201.1"}],"value":"XW47","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP55201.1"}]},{"referenceNumber":2,"citation":{"id":"15057449","citationType":"journal article","authors":["Yang Y.C.","Chou C.P.","Kuo T.T.","Lin S.H.","Yang M.K."],"citationCrossReferences":[{"database":"PubMed","id":"15057449"},{"database":"DOI","id":"10.1007/s00284-003-4191-5"}],"title":"PilR enhances the sensitivity of Xanthomonas axonopodis pv. citri to the infection of filamentous bacteriophage Cf.","publicationDate":"2004","journal":"Curr. Microbiol.","firstPage":"251","lastPage":"261","volume":"48"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP55201.1"}],"value":"XW47","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAP55201.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY295878","properties":[{"key":"ProteinId","value":"AAP55201.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"Q7X3U2","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0000156","properties":[{"key":"GoTerm","value":"F:phosphorelay response regulator activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0000155","properties":[{"key":"GoTerm","value":"F:phosphorelay sensor kinase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0030295","properties":[{"key":"GoTerm","value":"F:protein kinase activator activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0007234","properties":[{"key":"GoTerm","value":"P:osmosensory signaling via phosphorelay pathway"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd00075","properties":[{"key":"EntryName","value":"HATPase"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd00082","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.287.130","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.565.10","properties":[{"key":"EntryName","value":"Histidine kinase-like ATPase, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050351","properties":[{"key":"EntryName","value":"BphY/WalK/GraS-like"}]},{"database":"InterPro","id":"IPR036890","properties":[{"key":"EntryName","value":"HATPase_C_sf"}]},{"database":"InterPro","id":"IPR003594","properties":[{"key":"EntryName","value":"HATPase_dom"}]},{"database":"InterPro","id":"IPR005467","properties":[{"key":"EntryName","value":"His_kinase_dom"}]},{"database":"InterPro","id":"IPR003661","properties":[{"key":"EntryName","value":"HisK_dim/P_dom"}]},{"database":"InterPro","id":"IPR036097","properties":[{"key":"EntryName","value":"HisK_dim/P_sf"}]},{"database":"InterPro","id":"IPR004358","properties":[{"key":"EntryName","value":"Sig_transdc_His_kin-like_C"}]},{"database":"PANTHER","id":"PTHR42878:SF7","properties":[{"key":"EntryName","value":"SENSOR HISTIDINE KINASE GLRK"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42878","properties":[{"key":"EntryName","value":"TWO-COMPONENT HISTIDINE KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF25323","properties":[{"key":"EntryName","value":"6TM_PilS"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02518","properties":[{"key":"EntryName","value":"HATPase_c"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00512","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00344","properties":[{"key":"EntryName","value":"BCTRLSENSOR"}]},{"database":"SMART","id":"SM00387","properties":[{"key":"EntryName","value":"HATPase_c"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00388","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55874","properties":[{"key":"EntryName","value":"ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF47384","properties":[{"key":"EntryName","value":"Homodimeric domain of signal transducing histidine kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50109","properties":[{"key":"EntryName","value":"HIS_KIN"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MEIHASPWEKETTAACNADRRGGTSWDANGPPIVADHAVRRKIARDWPPDRSACAQADSVRRRCADRAPAYTRGSLQRGIGLASIASLIARIQSAPQRELYFFSLYRVLVAGLIAALVFSPLSDAIPEPRYPRLAAGVAIGYLCMAIPLLFWGRGERRLTPTVLCAVVADILAATLATHALPGASAGIAMMLLFNVAAASILLRLRYGMSIAVLASVAILLEYLWTLLEGGGATRPVAELAMFATSYVAVAFICEQIAARARRNQMLAEERGAQVANLYEINELIIRRMRTGVLVVDTHNHISLANEAALSLLGDGDQRTPSTDLSLVALTPELARRLQRWRSGWREEEAPLQLGAERPEVQPRFVRLLADSDLALVFLDDATVVSRRAESLTLSAMGRFSASLAHEIRNPLAAISYASQLLEESPDIGDADRRLLQIIHQQCQRTNGIVESVLALARRERATPDNLDLAAFVRRFVVEYRQTLSMETDILEASIQGSSVHALVDPKHLHQILTALVHNALKYGRVMDEPARVKLHVERLERKAVIDVIDRGPGIPDAVAAQLFRPFYTTSEHGTGLGLYIAQELCRANQAQLDYVSVPGGGACFRISLQGPNGLLGK","length":618,"molWeight":67508,"crc64":"7DC7C7CBAD5DACB3","md5":"0CCE536CD1344013261291B2FD387E2A"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1},"countByFeatureType":{"Transmembrane":6,"Domain":1,"Modified residue":1},"uniParcId":"UPI00001A9426"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A2PYF9","uniProtkbId":"A2PYF9_XANCI","entryAudit":{"firstPublicDate":"2007-03-06","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2007-03-06","entryVersion":35,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46269.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46269.1"}],"value":"Avirulence protein"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46269.1"}],"value":"hssB3.0"}}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004147"}],"value":"Host nucleus","id":"SL-0414"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004613"}],"value":"Secreted","id":"SL-0243"}}]}],"features":[{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":68,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":128,"modifier":"EXACT"},"end":{"value":152,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":944,"modifier":"EXACT"},"end":{"value":987,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":131,"modifier":"EXACT"},"end":{"value":141,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":142,"modifier":"EXACT"},"end":{"value":151,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":944,"modifier":"EXACT"},"end":{"value":956,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022562"}],"id":"KW-1048","category":"Cellular component","name":"Host nucleus"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022525"}],"id":"KW-0964","category":"Cellular component","name":"Secreted"}],"references":[{"referenceNumber":1,"citation":{"id":"17293422","citationType":"journal article","authors":["Shiotani H.","Fujikawa T.","Ishihara H.","Tsuyumu S.","Ozaki K."],"citationCrossReferences":[{"database":"PubMed","id":"17293422"},{"database":"DOI","id":"10.1128/JB.01790-06"}],"title":"A pthA homolog from Xanthomonas axonopodis pv. citri responsible for host-specific suppression of virulence.","publicationDate":"2007","journal":"J. Bacteriol.","firstPage":"3271","lastPage":"3279","volume":"189"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46269.1"}],"value":"KC21","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46269.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB175482","properties":[{"key":"ProteinId","value":"BAF46269.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A2PYF9","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005576","properties":[{"key":"GoTerm","value":"C:extracellular region"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0042025","properties":[{"key":"GoTerm","value":"C:host cell nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"Gene3D","id":"6.10.140.500","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"8"}]},{"database":"InterPro","id":"IPR005042","properties":[{"key":"EntryName","value":"TAL_effector_rpt"}]},{"database":"InterPro","id":"IPR053450","properties":[{"key":"EntryName","value":"TALE"}]},{"database":"NCBIfam","id":"NF041308","properties":[{"key":"EntryName","value":"AvrBs3"},{"key":"MatchStatus","value":"2"}]},{"database":"PANTHER","id":"PTHR42872","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMATE METHYLESTERASE/PROTEIN-GLUTAMINE GLUTAMINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42872:SF6","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMATE METHYLESTERASE_PROTEIN-GLUTAMINE GLUTAMINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03377","properties":[{"key":"EntryName","value":"TAL_effector"},{"key":"MatchStatus","value":"16"}]}],"sequence":{"value":"MDPIRSRTPSPARELLPGPQPDGVQPTADRGVSPPAGGPLDGLPARRTISRTRLPSPPAPSPAFSAGSFSDLLRQFDPSLFNTSLFDSLPPFGAHHTEAATGEWDEVQSGLRAADAPPPTMRVAVTAARPPRAKPAPRRRAAQPSDASPAAQVDLRTLGYSQQQQEKIKPKVRSTVAQHHEALVGHGFTHAHIVALSQHPAALGTVAVKYQDMIAALPEATHEAIVGVGKQWSGARALEALLTVAGELRGPPLQLDTGQLLKIAKRGGVTAVEAVHAWRNALTGAPLNLTPEQVVAIASNIGGKQALETVQALLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGRPALESIVAQLSRPDPALAALTNDHLVALACLGGRPALDAVKKGLPHAPALIKRTNRRIPERTSHRVADHAQVVRVLGFFQCHSHPAQAFDDAMTQFGMSRHGLLQLFRRVGVTELEARSGTLPPASQRWDRILQASGMKRAKPSPTSTQTPDQASLHAFADSLERDLDAPSPMHEGDQTRASSRKRSRSDRAVTGPSAQQSFEVRVPEQRDALHLPLSWRVKRPRTSIGGGLPDPGTPTAADLAASSTVMREQDEDPFAGAADDFPAFNEEELAWLMELLPQ","length":1060,"molWeight":111693,"crc64":"27A5DF7ACB5937E8","md5":"C9FD90FB3CF8824EC07BDA6021FC82C5"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Region":3,"Compositional bias":3},"uniParcId":"UPI0000F08898"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A2PYH5","uniProtkbId":"A2PYH5_XANCI","entryAudit":{"firstPublicDate":"2007-03-06","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2007-03-06","entryVersion":31,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46270.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46270.1"}],"value":"Avirulence protein"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46270.1"}],"value":"pB3.1"}}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004147"}],"value":"Host nucleus","id":"SL-0414"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004613"}],"value":"Secreted","id":"SL-0243"}}]}],"features":[{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":68,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":128,"modifier":"EXACT"},"end":{"value":152,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":980,"modifier":"EXACT"},"end":{"value":1018,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":131,"modifier":"EXACT"},"end":{"value":141,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":142,"modifier":"EXACT"},"end":{"value":151,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":980,"modifier":"EXACT"},"end":{"value":994,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022562"}],"id":"KW-1048","category":"Cellular component","name":"Host nucleus"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022525"}],"id":"KW-0964","category":"Cellular component","name":"Secreted"}],"references":[{"referenceNumber":1,"citation":{"id":"17293422","citationType":"journal article","authors":["Shiotani H.","Fujikawa T.","Ishihara H.","Tsuyumu S.","Ozaki K."],"citationCrossReferences":[{"database":"PubMed","id":"17293422"},{"database":"DOI","id":"10.1128/JB.01790-06"}],"title":"A pthA homolog from Xanthomonas axonopodis pv. citri responsible for host-specific suppression of virulence.","publicationDate":"2007","journal":"J. Bacteriol.","firstPage":"3271","lastPage":"3279","volume":"189"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46270.1"}],"value":"KC21","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46270.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB206387","properties":[{"key":"ProteinId","value":"BAF46270.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A2PYH5","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005576","properties":[{"key":"GoTerm","value":"C:extracellular region"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0042025","properties":[{"key":"GoTerm","value":"C:host cell nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"Gene3D","id":"6.10.140.500","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"8"}]},{"database":"InterPro","id":"IPR005042","properties":[{"key":"EntryName","value":"TAL_effector_rpt"}]},{"database":"InterPro","id":"IPR053450","properties":[{"key":"EntryName","value":"TALE"}]},{"database":"NCBIfam","id":"NF041308","properties":[{"key":"EntryName","value":"AvrBs3"},{"key":"MatchStatus","value":"2"}]},{"database":"PANTHER","id":"PTHR42872","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMATE METHYLESTERASE/PROTEIN-GLUTAMINE GLUTAMINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42872:SF6","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMATE METHYLESTERASE_PROTEIN-GLUTAMINE GLUTAMINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03377","properties":[{"key":"EntryName","value":"TAL_effector"},{"key":"MatchStatus","value":"17"}]}],"sequence":{"value":"MDPIRSRTPSPARELLPGPQPDGVQPTADRGVSPPAGGPLDGLPARRTISRTRLPSPPAPSPAFSAGSFSDLLRQFDPSLFNTSLFDSLPPFGAHHTEAATGEWDEVQSGLRAADAPPPTMRVAVTAARPPRAKPAPRRRAAQPSDASPAAQVDLRTLGYSQQQQEKIKPKVRSTVAQHHEALVGHGFTHAHIVALSQHPAALGTVAVKYQDMIAALPEATHEAIVGVGKQWSGARALEALLTVAGELRGPPLQLDTGQLLKIAKRGGVTAVEAVHAWRNALTGAPLNLTPEQVVAIASNIGGKQALETVQALLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGRPALESIVAQLSRPDPALAALTNDHLVALACLGGRPALDAVKKGLPHAPALIKRTNRRIPERTSHRVADHAQVVRVLGFFQCHSHPAQAFDDAMTQFGMSRHGLLQLFRRVGVTELEARSGTLPPASQRWDRILQASGMKRAKPSPTSTQTPDQASLHAFADSLERDLDAPSPTHEGDQRRASSRKRSRSDRAVTGPSAQQSFEVRVPEQRDALHLPLSWRVKRPRTSIGGGLPDPGTPTAADLAASSTVMREQDEDPFAGAADDFPAFNEEELAWLMELLPQ","length":1096,"molWeight":115420,"crc64":"B11259B94E899A5E","md5":"120EE7B30C6F770B1D2E96671CEFDE70"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Region":3,"Compositional bias":3},"uniParcId":"UPI0000F08899"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A2PYH6","uniProtkbId":"A2PYH6_XANCI","entryAudit":{"firstPublicDate":"2007-03-06","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2007-03-06","entryVersion":34,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46271.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46271.1"}],"value":"Avirulence protein"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46271.1"}],"value":"pthA-KC21"}}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004147"}],"value":"Host nucleus","id":"SL-0414"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004613"}],"value":"Secreted","id":"SL-0243"}}]}],"features":[{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":68,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":128,"modifier":"EXACT"},"end":{"value":152,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1047,"modifier":"EXACT"},"end":{"value":1085,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":131,"modifier":"EXACT"},"end":{"value":141,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":142,"modifier":"EXACT"},"end":{"value":151,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1047,"modifier":"EXACT"},"end":{"value":1061,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022562"}],"id":"KW-1048","category":"Cellular component","name":"Host nucleus"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022525"}],"id":"KW-0964","category":"Cellular component","name":"Secreted"}],"references":[{"referenceNumber":1,"citation":{"id":"17293422","citationType":"journal article","authors":["Shiotani H.","Fujikawa T.","Ishihara H.","Tsuyumu S.","Ozaki K."],"citationCrossReferences":[{"database":"PubMed","id":"17293422"},{"database":"DOI","id":"10.1128/JB.01790-06"}],"title":"A pthA homolog from Xanthomonas axonopodis pv. citri responsible for host-specific suppression of virulence.","publicationDate":"2007","journal":"J. Bacteriol.","firstPage":"3271","lastPage":"3279","volume":"189"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46271.1"}],"value":"KC21","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46271.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB206388","properties":[{"key":"ProteinId","value":"BAF46271.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A2PYH6","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A2PYH6","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005576","properties":[{"key":"GoTerm","value":"C:extracellular region"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0042025","properties":[{"key":"GoTerm","value":"C:host cell nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"Gene3D","id":"6.10.140.500","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"9"}]},{"database":"InterPro","id":"IPR005042","properties":[{"key":"EntryName","value":"TAL_effector_rpt"}]},{"database":"InterPro","id":"IPR053450","properties":[{"key":"EntryName","value":"TALE"}]},{"database":"NCBIfam","id":"NF041308","properties":[{"key":"EntryName","value":"AvrBs3"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42872","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMATE METHYLESTERASE/PROTEIN-GLUTAMINE GLUTAMINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42872:SF6","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMATE METHYLESTERASE_PROTEIN-GLUTAMINE GLUTAMINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03377","properties":[{"key":"EntryName","value":"TAL_effector"},{"key":"MatchStatus","value":"19"}]}],"sequence":{"value":"MDPIRSRTPSPARELLPGPQPDGVQPTADRGVSPPAGGPLDGLPARRTISRTRLPSPPAPSPAFSAGSFSDLLRQFDPSLFNTSLFDSLPPFGAHHTEAATGEWDEVQSGLRAADAPPPTMRVAVTAARPPRAKPAPRRRAAQPSDASPAAQVDLRTLGYSQQQQEKIKPKVRSTVAQHHEALVGHGFTHAHIVALSQHPAALGTVAVKYQDMIAALPEATHEAIVGVGKQWSGARALEALLTVAGELRGPPLQLDTGQLLKIAKRGGVTAVEAVHAWRNALTGAPLNLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPQQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNSGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIACNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGRPALESIVAQLSRPDPALAALTNDHLVALACLGGRPALDAVKKGLPHAPALIKRTNRRIPERTSHRVADHAQVVRVLGFFQCHSHPAQAFDDAMTQFGMSRHGLLQLFRRVGVTELEARSGTLPPASQRWDRILQASGMKRAKPSPTSTQTPDQASLHAFADSLERDLDAPSPTHEGDQRRASSRKRSRSDRAVTGPSAQQSFEVRVPEQRDALHLPLSWRVKRPRTSIGGGLPDPGTPTAADLAASSTVMREQDEDPFAGAADDFPAFNEEELAWLMELLPQ","length":1163,"molWeight":122294,"crc64":"AA7A92D32C462733","md5":"139DEAFC38822502E05D2E911C28AFB2"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Region":3,"Compositional bias":3},"uniParcId":"UPI0000F0889A"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A2PYH7","uniProtkbId":"A2PYH7_XANCI","entryAudit":{"firstPublicDate":"2007-03-06","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2007-03-06","entryVersion":31,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46272.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46272.1"}],"value":"Avirulence protein"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46272.1"}],"value":"pB3.7"}}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004147"}],"value":"Host nucleus","id":"SL-0414"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004613"}],"value":"Secreted","id":"SL-0243"}}]}],"features":[{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":68,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":128,"modifier":"EXACT"},"end":{"value":152,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1179,"modifier":"EXACT"},"end":{"value":1217,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":131,"modifier":"EXACT"},"end":{"value":141,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":142,"modifier":"EXACT"},"end":{"value":151,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1179,"modifier":"EXACT"},"end":{"value":1193,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022562"}],"id":"KW-1048","category":"Cellular component","name":"Host nucleus"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022525"}],"id":"KW-0964","category":"Cellular component","name":"Secreted"}],"references":[{"referenceNumber":1,"citation":{"id":"17293422","citationType":"journal article","authors":["Shiotani H.","Fujikawa T.","Ishihara H.","Tsuyumu S.","Ozaki K."],"citationCrossReferences":[{"database":"PubMed","id":"17293422"},{"database":"DOI","id":"10.1128/JB.01790-06"}],"title":"A pthA homolog from Xanthomonas axonopodis pv. citri responsible for host-specific suppression of virulence.","publicationDate":"2007","journal":"J. Bacteriol.","firstPage":"3271","lastPage":"3279","volume":"189"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46272.1"}],"value":"KC21","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAF46272.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB206389","properties":[{"key":"ProteinId","value":"BAF46272.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"GO","id":"GO:0005576","properties":[{"key":"GoTerm","value":"C:extracellular region"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0042025","properties":[{"key":"GoTerm","value":"C:host cell nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"Gene3D","id":"6.10.140.500","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"12"}]},{"database":"InterPro","id":"IPR005042","properties":[{"key":"EntryName","value":"TAL_effector_rpt"}]},{"database":"InterPro","id":"IPR053450","properties":[{"key":"EntryName","value":"TALE"}]},{"database":"NCBIfam","id":"NF041308","properties":[{"key":"EntryName","value":"AvrBs3"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42872","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMATE METHYLESTERASE/PROTEIN-GLUTAMINE GLUTAMINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42872:SF6","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMATE METHYLESTERASE_PROTEIN-GLUTAMINE GLUTAMINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03377","properties":[{"key":"EntryName","value":"TAL_effector"},{"key":"MatchStatus","value":"23"}]}],"sequence":{"value":"MDPIRSRTPSPARELLPGPQPDGVQPTADRGVSPPAGGPLDGLPARRTMSRTRLPSPPAPSPAFSAGSFSDLLRQFDPSLFNTSLFDSLPPFGAHHTEAATGEWDEVQSGLRAADAPPPTMRVAVTAARPPRAKPAPRRRAAQPSDASPAAQVDLRTLGYSQQQQEKIKPKVRSTVAQHHEALVGHGFTHAHIVALSQHPAALGTVAVKYQDMIAALPEATHEAIVGVGKQWSGARALEALLTVAGELRGPPLQLDTGQLLKIAKRGGVTAVEAVYAWRNALTGAPLNLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGRPALESIVAQLSRPDPALAALTNDHLVALACLGGRPALDAVKKGLPHAPALIKRTNRRIPERTSHRVADHAQVVRVLGFFQCHSHPAQAFDDAMTQFGMSRHGLLQLFRRVGVTELEARSGTLPPASQRWDRILQASGMKRAKPSPTSTQTPDQASLHAFADSLERDLDAPSPTHEGDQRRASSRKRSRSDRAVTGPSAQQSFEVRVPEQRDALHLPLSWRVKRPRTSIGGGLPDPGTPTAADLAASSTVMREQDEDPFAGAADDFPVFNEEELAWLMELLPQ","length":1295,"molWeight":136238,"crc64":"6A9E67421421BD5E","md5":"D8DF8707C04885C28D0CC78A475CD54A"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Region":3,"Compositional bias":3},"uniParcId":"UPI0000F0889B"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A7LD73","secondaryAccessions":["A9UHA5"],"uniProtkbId":"A7LD73_XANCI","entryAudit":{"firstPublicDate":"2007-09-11","lastAnnotationUpdateDate":"2025-04-02","lastSequenceUpdateDate":"2007-09-11","entryVersion":31,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABS19000.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABS19000.1"},{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABX84268.1"}],"value":"Gyrase B"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABS19000.1"}],"value":"gyrB"}}],"features":[{"type":"Domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":156,"modifier":"EXACT"}},"description":"DNA gyrase subunit B insert","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF18053"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABS19000.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":176,"modifier":"EXACT"},"end":{"value":176,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABS19000.1"}]}],"references":[{"referenceNumber":1,"citation":{"id":"18048743","citationType":"journal article","authors":["Parkinson N.","Aritua V.","Heeney J.","Cowie C.","Bew J.","Stead D."],"citationCrossReferences":[{"database":"PubMed","id":"18048743"},{"database":"DOI","id":"10.1099/ijs.0.65220-0"}],"title":"Phylogenetic analysis of Xanthomonas species by comparison of partial gyrase B gene sequences.","publicationDate":"2007","journal":"Int. J. Syst. Evol. Microbiol.","firstPage":"2881","lastPage":"2887","volume":"57"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABS19000.1"}],"value":"LMG 9322","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABS19000.1"}]},{"referenceNumber":2,"citation":{"id":"CI-16B6JL74R37TH","citationType":"submission","authors":["Parkinson N.M.","Cowie C.","Heeney J.","Stead D."],"publicationDate":"NOV-2007","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABX84268.1"}],"value":"NCPPB409","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABX84268.1"}]},{"referenceNumber":3,"citation":{"id":"19196764","citationType":"journal article","authors":["Parkinson N.","Cowie C.","Heeney J.","Stead D."],"citationCrossReferences":[{"database":"PubMed","id":"19196764"},{"database":"DOI","id":"10.1099/ijs.0.65825-0"}],"title":"Phylogenetic structure of Xanthomonas determined by comparison of gyrB sequences.","publicationDate":"2009","journal":"Int. J. Syst. Evol. Microbiol.","firstPage":"264","lastPage":"274","volume":"59"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABX84268.1"}],"value":"NCPPB409","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABX84268.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"EU007540","properties":[{"key":"ProteinId","value":"ABS19000.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"EU285147","properties":[{"key":"ProteinId","value":"ABX84268.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A7LD73","properties":[{"key":"Description","value":"-"}]},{"database":"Gene3D","id":"3.10.20.690","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.1490.440","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR041423","properties":[{"key":"EntryName","value":"GyrB_insert"}]},{"database":"Pfam","id":"PF18053","properties":[{"key":"EntryName","value":"GyrB_insert"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"ITGEALEKLLMLFTSANEAIARNAHRYDPALLTALIDLPPLDVEKLQAEGDQHPTLDALQAVLNRGTLGTARYQLRFDPGSDNAPATLVAIRRHMGEEFTQVLPMGAFESGELRPLREVSLALHDLVREGAQIVRGNKSHPITSFAQAHAWLLDEAKKGRQVQRFKGLGEMNAEQL","length":176,"molWeight":19396,"crc64":"BF2F54E4A01B7547","md5":"63722280C958B525D500F3771D6CECDA"},"extraAttributes":{"countByFeatureType":{"Domain":1,"Non-terminal residue":2},"uniParcId":"UPI000158AB06"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"C8YL90","uniProtkbId":"C8YL90_XANCI","entryAudit":{"firstPublicDate":"2009-11-03","lastAnnotationUpdateDate":"2025-04-02","lastSequenceUpdateDate":"2009-11-03","entryVersion":43,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72425.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72425.1"}],"value":"RpoD"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72425.1"}],"value":"rpoD"}}],"features":[{"type":"Domain","location":{"start":{"value":6,"modifier":"EXACT"},"end":{"value":37,"modifier":"EXACT"}},"description":"RNA polymerase sigma-70 region 1.2","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF00140"}]},{"type":"Domain","location":{"start":{"value":47,"modifier":"EXACT"},"end":{"value":261,"modifier":"EXACT"}},"description":"RNA polymerase sigma factor 70 non-essential","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF04546"}]},{"type":"Region","location":{"start":{"value":96,"modifier":"EXACT"},"end":{"value":128,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":98,"modifier":"EXACT"},"end":{"value":120,"modifier":"EXACT"}},"description":"Acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72425.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":261,"modifier":"EXACT"},"end":{"value":261,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72425.1"}]}],"references":[{"referenceNumber":1,"citation":{"id":"19680562","citationType":"journal article","authors":["Hajri A.","Brin C.","Hunault G.","Lardeux F.","Lemaire C.","Manceau C.","Boureau T.","Poussier S."],"citationCrossReferences":[{"database":"PubMed","id":"19680562"},{"database":"DOI","id":"10.1371/journal.pone.0006632"}],"title":"A 'repertoire for repertoire' hypothesis: repertoires of type three effectors are candidate determinants of host specificity in Xanthomonas.","publicationDate":"2009","journal":"PLoS ONE","firstPage":"E6632","lastPage":"E6632","volume":"4"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72425.1"}],"value":"CFBP1209","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72433.1"}],"value":"CFBP1814","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72442.1"}],"value":"CFBP2525","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72449.1"}],"value":"CFBP2900","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72461.1"}],"value":"CFBP3369","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72478.1"}],"value":"CFBP5280","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72479.1"}],"value":"CFBP5284","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ACV72425.1"}]},{"referenceNumber":2,"citation":{"id":"23505513","citationType":"journal article","authors":["Mhedbi-Hajri N.","Hajri A.","Boureau T.","Darrasse A.","Durand K.","Brin C.","Saux M.F.","Manceau C.","Poussier S.","Pruvost O.","Lemaire C.","Jacques M.A."],"citationCrossReferences":[{"database":"PubMed","id":"23505513"}],"title":"Evolutionary History of the Plant Pathogenic Bacterium Xanthomonas axonopodis.","publicationDate":"2013","journal":"PLoS ONE","firstPage":"E58474","lastPage":"E58474","volume":"8"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AER61355.1"}],"value":"JF90_8","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AER61356.1"}],"value":"JJ60_1","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AER61357.1"}],"value":"JK2_20","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AER61358.1"}],"value":"JS582","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AER61359.1"}],"value":"LB302","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AER61355.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"FJ561596","properties":[{"key":"ProteinId","value":"ACV72425.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"FJ561604","properties":[{"key":"ProteinId","value":"ACV72433.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"FJ561613","properties":[{"key":"ProteinId","value":"ACV72442.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"FJ561620","properties":[{"key":"ProteinId","value":"ACV72449.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"FJ561632","properties":[{"key":"ProteinId","value":"ACV72461.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"FJ561649","properties":[{"key":"ProteinId","value":"ACV72478.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"FJ561650","properties":[{"key":"ProteinId","value":"ACV72479.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"HQ591334","properties":[{"key":"ProteinId","value":"AER61355.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"HQ591335","properties":[{"key":"ProteinId","value":"AER61356.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"HQ591336","properties":[{"key":"ProteinId","value":"AER61357.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"HQ591337","properties":[{"key":"ProteinId","value":"AER61358.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"HQ591338","properties":[{"key":"ProteinId","value":"AER61359.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"C8YL90","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"C8YL90","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0003677","properties":[{"key":"GoTerm","value":"F:DNA binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016987","properties":[{"key":"GoTerm","value":"F:sigma factor activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006352","properties":[{"key":"GoTerm","value":"P:DNA-templated transcription initiation"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"1.10.601.10","properties":[{"key":"EntryName","value":"RNA Polymerase Primary Sigma Factor"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR009042","properties":[{"key":"EntryName","value":"RNA_pol_sigma70_r1_2"}]},{"database":"InterPro","id":"IPR007631","properties":[{"key":"EntryName","value":"RNA_pol_sigma_70_non-ess"}]},{"database":"InterPro","id":"IPR013325","properties":[{"key":"EntryName","value":"RNA_pol_sigma_r2"}]},{"database":"Pfam","id":"PF04546","properties":[{"key":"EntryName","value":"Sigma70_ner"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00140","properties":[{"key":"EntryName","value":"Sigma70_r1_2"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF88946","properties":[{"key":"EntryName","value":"Sigma2 domain of RNA polymerase sigma factors"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"GGRTTDPVRMYMREMGTVELLTREGEIAIAKRIEEGLSQVQAALGVFPLSTEMLLADYEAHKEGKKRLAEIVVGFNDLIEEADAAAAALAAAGPVAVSDDEAVDEDDDEDGDDEAAEEEAGPTGPDPVEVATRMENLANEYAKFKKVYAKNGAEHKLVVKAREDMAAIFTTLKLPLPLTDALVTQLRGVVNGIKDHERKVLHLATTVARMPRKDFIRSWEGNQTNLEWVEDALKRKQKWSSALRDVKDQIISEQQGSIEME","length":261,"molWeight":28758,"crc64":"66042E7E274ACFB1","md5":"5803CC516E9E479584FBD882C44D4D63"},"extraAttributes":{"countByFeatureType":{"Domain":2,"Region":1,"Compositional bias":1,"Non-terminal residue":2},"uniParcId":"UPI0001B71E31"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"O82880","uniProtkbId":"O82880_XANCI","entryAudit":{"firstPublicDate":"1998-11-01","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"1998-11-01","entryVersion":112,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAA32731.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00071032"}],"value":"HTH-type DNA-binding transcriptional activator EutR"}},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00081697"}],"value":"Ethanolamine operon regulatory protein"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAA32731.1"}],"value":"hrpXct"}}],"features":[{"type":"Domain","location":{"start":{"value":375,"modifier":"EXACT"},"end":{"value":476,"modifier":"EXACT"}},"description":"HTH araC/xylS-type","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS01124"}]},{"type":"DNA binding","location":{"start":{"value":393,"modifier":"EXACT"},"end":{"value":414,"modifier":"EXACT"}},"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00593"}]},{"type":"DNA binding","location":{"start":{"value":443,"modifier":"EXACT"},"end":{"value":466,"modifier":"EXACT"}},"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00593"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023159"}],"id":"KW-0010","category":"Molecular function","name":"Activator"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023125"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00593"}],"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023163"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00593"}],"id":"KW-0804","category":"Biological process","name":"Transcription"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023015"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00593"}],"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"10902926","citationType":"journal article","authors":["Iwamoto M.","Oku T."],"citationCrossReferences":[{"database":"PubMed","id":"10902926"}],"title":"Cloning and molecular characterization of hrpX from Xanthomonas axonopodis pv. citri.","publicationDate":"2000","journal":"DNA Seq.","firstPage":"167","lastPage":"173","volume":"11"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAA32731.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB011449","properties":[{"key":"ProteinId","value":"BAA32731.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"O82880","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0003700","properties":[{"key":"GoTerm","value":"F:DNA-binding transcription factor activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0043565","properties":[{"key":"GoTerm","value":"F:sequence-specific DNA binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006351","properties":[{"key":"GoTerm","value":"P:DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"FunFam","id":"1.10.10.60:FF:000153","properties":[{"key":"EntryName","value":"HTH-type transcriptional regulator EutR"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.10.60","properties":[{"key":"EntryName","value":"Homeodomain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.25.40.10","properties":[{"key":"EntryName","value":"Tetratricopeptide repeat domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050204","properties":[{"key":"EntryName","value":"AraC_XylS_family_regulators"}]},{"database":"InterPro","id":"IPR009057","properties":[{"key":"EntryName","value":"Homeodomain-like_sf"}]},{"database":"InterPro","id":"IPR018060","properties":[{"key":"EntryName","value":"HTH_AraC"}]},{"database":"InterPro","id":"IPR018062","properties":[{"key":"EntryName","value":"HTH_AraC-typ_CS"}]},{"database":"InterPro","id":"IPR011990","properties":[{"key":"EntryName","value":"TPR-like_helical_dom_sf"}]},{"database":"PANTHER","id":"PTHR46796:SF12","properties":[{"key":"EntryName","value":"HTH-TYPE DNA-BINDING TRANSCRIPTIONAL ACTIVATOR EUTR"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR46796","properties":[{"key":"EntryName","value":"HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAS-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF12833","properties":[{"key":"EntryName","value":"HTH_18"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00342","properties":[{"key":"EntryName","value":"HTH_ARAC"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF46689","properties":[{"key":"EntryName","value":"Homeodomain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF48452","properties":[{"key":"EntryName","value":"TPR-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00041","properties":[{"key":"EntryName","value":"HTH_ARAC_FAMILY_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS01124","properties":[{"key":"EntryName","value":"HTH_ARAC_FAMILY_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MILSTYFAAISALSYAERLPTYTSRMLVGAWPQGLQHLQQRRDGQGAVDGADDEVSLFGASGDALLILEYQEEAEDAYRQALKAMRGHQRQLRLLSCRNTAWLMLSQRRLSAALNCFAQLAMDRETSPSLCGESLLGKSLTHFHLGQSTLALQTLERASEVLADLESGASEWLRIANALRLDMIAQLRIRRSDRMSNHVFWQAQLRQEDAAHAFEPSDLRACIADLAESMPVLAHAMRHVRTLLRIAGGDTFGFDAQIDALPAAATGCPPCARQDAQVELALAALAVGRADLAERALAGAGRHHAPRWNLEFEYCQAKISQAMGRTEQALLLYNRYALDAVQCLRSEVQAPRLLESGTPAHVSDDISARLPAKYRRAYSYMITNAHRSDLSINEVAAQIGVTGRALQQAFKSATGLSPTQVLRRYRMQSIRDELLAEGGCGSVLQAASRWGVGSRSALAKGYRQHFNEAPMETLQR","length":476,"molWeight":52432,"crc64":"C7F14E66DEAB7771","md5":"A268EB0F86982FDB272E341D648E38BD"},"extraAttributes":{"countByFeatureType":{"Domain":1,"DNA binding":2},"uniParcId":"UPI00000B7244"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q2V8B3","uniProtkbId":"Q2V8B3_XANCI","entryAudit":{"firstPublicDate":"2006-01-10","lastAnnotationUpdateDate":"2026-06-10","lastSequenceUpdateDate":"2006-01-10","entryVersion":18,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABB89548.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABB89548.1"}],"value":"HrpE"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABB89548.1"}],"value":"hrpE"}}],"references":[{"referenceNumber":1,"citation":{"id":"16452423","citationType":"journal article","authors":["Weber E.","Koebnik R."],"citationCrossReferences":[{"database":"PubMed","id":"16452423"},{"database":"DOI","id":"10.1128/JB.188.4.1405-1410.2006"}],"title":"Positive selection of the Hrp pilin HrpE of the plant pathogen Xanthomonas.","publicationDate":"2006","journal":"J. Bacteriol.","firstPage":"1405","lastPage":"1410","volume":"188"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABB89548.1"}],"value":"50E","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABB89548.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ286697","properties":[{"key":"ProteinId","value":"ABB89548.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"Q2V8B3","properties":[{"key":"Description","value":"-"}]},{"database":"InterPro","id":"IPR048137","properties":[{"key":"EntryName","value":"HrpE-like"}]},{"database":"NCBIfam","id":"NF041507","properties":[{"key":"EntryName","value":"HrpE_Xanth"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF28047","properties":[{"key":"EntryName","value":"HrpE-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MQLFPEISSINSRYHQGMDGATGGVSNGISGAGAISGANGQMESLLDDLIASDEAQKSMNNKITMLKNDLDFNVALNKFIGKAGDNAKQLVGQ","length":93,"molWeight":9732,"crc64":"C5A56FDB222A5B1F","md5":"544A5B898D50B1CA6D02E93D538AB775"},"extraAttributes":{"uniParcId":"UPI00006620AD"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q56780","uniProtkbId":"Q56780_XANCI","entryAudit":{"firstPublicDate":"1996-11-01","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"1996-11-01","entryVersion":49,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAC43587.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAC43587.1"}],"value":"PthA"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAC43587.1"}],"value":"pthA"}}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004147"}],"value":"Host nucleus","id":"SL-0414"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004613"}],"value":"Secreted","id":"SL-0243"}}]}],"features":[{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":68,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":128,"modifier":"EXACT"},"end":{"value":152,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1047,"modifier":"EXACT"},"end":{"value":1090,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1105,"modifier":"EXACT"},"end":{"value":1124,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":131,"modifier":"EXACT"},"end":{"value":141,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":142,"modifier":"EXACT"},"end":{"value":151,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1047,"modifier":"EXACT"},"end":{"value":1061,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022562"}],"id":"KW-1048","category":"Cellular component","name":"Host nucleus"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022525"}],"id":"KW-0964","category":"Cellular component","name":"Secreted"}],"references":[{"referenceNumber":1,"citation":{"id":"1421509","citationType":"journal article","authors":["Swarup S.","Yang Y.","Kingsley M.T.","Gabriel D.W."],"citationCrossReferences":[{"database":"PubMed","id":"1421509"}],"title":"An Xanthomonas citri pathogenicity gene, pthA, pleiotropically encodes gratuitous avirulence on nonhosts.","publicationDate":"1992","journal":"Mol. Plant Microbe Interact.","firstPage":"204","lastPage":"213","volume":"5"},"referencePositions":["NUCLEOTIDE SEQUENCE OF 1-38 AND 271-331"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAC43587.1"}],"value":"3213","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAC43587.1"}]},{"referenceNumber":2,"citation":{"id":"7665472","citationType":"journal article","authors":["Yang Y.","Gabriel D.W."],"citationCrossReferences":[{"database":"PubMed","id":"7665472"}],"title":"Intragenic recombination of a single plant pathogen gene provides a mechanism for the evolution of new host specificities.","publicationDate":"1995","journal":"J. Bacteriol.","firstPage":"4963","lastPage":"4968","volume":"177"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAC43587.1"}],"value":"3213","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAC43587.1"}]},{"referenceNumber":3,"citation":{"id":"8589417","citationType":"journal article","authors":["Yang Y.","Gabriel D.W."],"citationCrossReferences":[{"database":"PubMed","id":"8589417"}],"title":"Xanthomonas avirulence/pathogenicity gene family encodes functional plant nuclear targeting signals.","publicationDate":"1995","journal":"Mol. Plant Microbe Interact.","firstPage":"627","lastPage":"631","volume":"8"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAC43587.1"}],"value":"3213","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAC43587.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"U28802","properties":[{"key":"ProteinId","value":"AAC43587.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"Q56780","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q56780","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005576","properties":[{"key":"GoTerm","value":"C:extracellular region"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0042025","properties":[{"key":"GoTerm","value":"C:host cell nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"Gene3D","id":"6.10.140.500","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"9"}]},{"database":"InterPro","id":"IPR005042","properties":[{"key":"EntryName","value":"TAL_effector_rpt"}]},{"database":"InterPro","id":"IPR053450","properties":[{"key":"EntryName","value":"TALE"}]},{"database":"NCBIfam","id":"NF041308","properties":[{"key":"EntryName","value":"AvrBs3"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42872","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMATE METHYLESTERASE/PROTEIN-GLUTAMINE GLUTAMINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42872:SF6","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMATE METHYLESTERASE_PROTEIN-GLUTAMINE GLUTAMINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03377","properties":[{"key":"EntryName","value":"TAL_effector"},{"key":"MatchStatus","value":"19"}]}],"sequence":{"value":"MDPIRSRTPSPARELLPGPQPDGVQPTADRGVSPPAGGPLDGLPARRTMSRTRLPSPPAPSPAFSAGSFSDLLRQFDPSLFNTSLFDSLPPFGAHHTEAATGEWDEVQSGLRAADAPPPTMRVAVTAARPPRAKPAPRRRAAQPSDASPAAQVDLRTLGYSQQQQEKIKPKVRSTVAQHHEALVGHGFTHAHIVALSQHPAALGTVAVKYQDMIAALPEATHEAIVGVGKQWSGARALEALLTVAGELRGPPLQLDTGQLLKIAKRGGVTAVEAVHAWRNALTGAPLNLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPQQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTLDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNSGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIACNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGRPALESIVAQLSRPDPALAALTNDHLVALACLGGRPALDAVKKGLPHAPALIKRTNRRIPERTSHRVADHAQVVRVLGFFQCHSHPAQAFDDAMTQFGMSRHGLLQLFRRVGVTELEARSGTLPPASQRWDRILQASGMKRAKPSPTSTQTPDQASLHAFADSLERDLDAPSPTHEGDQRRASSRKRSRSDRAVTGPSAQQSFEVRAPEQRDALHLPLSWRVKRPRTSIGGGLPDPGTPTAADLAASSTVMREQDEDPFAGAADDFPAFNEEELAWLMELLPQ","length":1163,"molWeight":122249,"crc64":"92E2F4F9679BFD27","md5":"5DE93223F8F49FBD234F40281356E87C"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Region":4,"Compositional bias":3},"uniParcId":"UPI00000B34C1"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q5BMU0","uniProtkbId":"Q5BMU0_XANCI","entryAudit":{"firstPublicDate":"2012-04-18","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2012-04-18","entryVersion":26,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24183.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24183.1"}],"value":"Uncharacterized protein orf83"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24183.1"}],"value":"orf83"}}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":82,"modifier":"EXACT"},"end":{"value":82,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24183.1"}]}],"references":[{"referenceNumber":1,"citation":{"id":"15755815","citationType":"journal article","authors":["Gillings M.R.","Holley M.P.","Stokes H.W.","Holmes A.J."],"citationCrossReferences":[{"database":"PubMed","id":"15755815"},{"database":"DOI","id":"10.1073/pnas.0406620102"}],"title":"Integrons in Xanthomonas: a source of species genome diversity.","publicationDate":"2005","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"4419","lastPage":"4424","volume":"102"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24174.1"}],"value":"DAR72029","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24183.1"}],"value":"DAR73889","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24183.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY928780","properties":[{"key":"ProteinId","value":"AAX24174.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY928783","properties":[{"key":"ProteinId","value":"AAX24183.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_005915237.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP059992.1"}]},{"database":"AlphaFoldDB","id":"Q5BMU0","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"66909555","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"AGTNHDW","properties":[{"key":"Fingerprint","value":"-"}]}],"sequence":{"value":"MENYQLVTSPLCRSVTTDGRTIRLEIYRGPDTGWTLEAVDEFNNSTVWDDLFATDQAALDEALRTIRDEGIDSLIGPPSGVH","length":82,"molWeight":9127,"crc64":"41B6EE17B977A3AD","md5":"D7D20935E0531FBAC33B0455E24FFFD6"},"extraAttributes":{"countByFeatureType":{"Non-terminal residue":1},"uniParcId":"UPI00000D7A50"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q5BMV0","uniProtkbId":"Q5BMV0_XANCI","entryAudit":{"firstPublicDate":"2012-04-18","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2012-04-18","entryVersion":35,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24173.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24173.1"}],"value":"ISxac3 transposase"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24173.1"}],"value":"orf269"}}],"features":[{"type":"Domain","location":{"start":{"value":105,"modifier":"EXACT"},"end":{"value":195,"modifier":"EXACT"}},"description":"Integrase catalytic","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50994"}]},{"type":"Region","location":{"start":{"value":229,"modifier":"EXACT"},"end":{"value":248,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Binding site","location":{"start":{"value":116,"modifier":"EXACT"},"end":{"value":116,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:18420"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00457"}],"ligand":{"name":"Mg(2+)","id":"ChEBI:CHEBI:18420","note":"catalytic"}},{"type":"Binding site","location":{"start":{"value":176,"modifier":"EXACT"},"end":{"value":176,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:18420"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00457"}],"ligand":{"name":"Mg(2+)","id":"ChEBI:CHEBI:18420","note":"catalytic"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00457"}],"id":"KW-0229","category":"Biological process","name":"DNA integration"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00457"}],"id":"KW-0233","category":"Biological process","name":"DNA recombination"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00457"}],"id":"KW-0255","category":"Molecular function","name":"Endonuclease"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00457"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00457"}],"id":"KW-0540","category":"Molecular function","name":"Nuclease"}],"references":[{"referenceNumber":1,"citation":{"id":"15755815","citationType":"journal article","authors":["Gillings M.R.","Holley M.P.","Stokes H.W.","Holmes A.J."],"citationCrossReferences":[{"database":"PubMed","id":"15755815"},{"database":"DOI","id":"10.1073/pnas.0406620102"}],"title":"Integrons in Xanthomonas: a source of species genome diversity.","publicationDate":"2005","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"4419","lastPage":"4424","volume":"102"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24173.1"}],"value":"DAR72029","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24182.1"}],"value":"DAR73889","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24173.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY928780","properties":[{"key":"ProteinId","value":"AAX24173.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY928783","properties":[{"key":"ProteinId","value":"AAX24182.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"Q5BMV0","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0004519","properties":[{"key":"GoTerm","value":"F:endonuclease activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0016787","properties":[{"key":"GoTerm","value":"F:hydrolase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0003676","properties":[{"key":"GoTerm","value":"F:nucleic acid binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0015074","properties":[{"key":"GoTerm","value":"P:DNA integration"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006313","properties":[{"key":"GoTerm","value":"P:DNA transposition"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"Gene3D","id":"3.30.420.10","properties":[{"key":"EntryName","value":"Ribonuclease H-like superfamily/Ribonuclease H"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR025948","properties":[{"key":"EntryName","value":"HTH-like_dom"}]},{"database":"InterPro","id":"IPR001584","properties":[{"key":"EntryName","value":"Integrase_cat-core"}]},{"database":"InterPro","id":"IPR012337","properties":[{"key":"EntryName","value":"RNaseH-like_sf"}]},{"database":"InterPro","id":"IPR036397","properties":[{"key":"EntryName","value":"RNaseH_sf"}]},{"database":"InterPro","id":"IPR048020","properties":[{"key":"EntryName","value":"Transpos_IS3"}]},{"database":"InterPro","id":"IPR050900","properties":[{"key":"EntryName","value":"Transposase_IS3/IS150/IS904"}]},{"database":"NCBIfam","id":"NF033516","properties":[{"key":"EntryName","value":"transpos_IS3"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR46889","properties":[{"key":"EntryName","value":"TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3B-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR46889:SF4","properties":[{"key":"EntryName","value":"TRANSPOSASE INSO FOR INSERTION SEQUENCE ELEMENT IS911B-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13276","properties":[{"key":"EntryName","value":"HTH_21"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00665","properties":[{"key":"EntryName","value":"rve"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF53098","properties":[{"key":"EntryName","value":"Ribonuclease H-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50994","properties":[{"key":"EntryName","value":"INTEGRASE"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MCRVLRVNRAGYYAWLKSPDSERAKEDERLLGLIKHHWLASGSVYGHRKIAKDLRDLGERCSRHRVHRLMRTEGLRAQVGYGRKPRFHGGTPCKAAANLLDRQFDVTEPDTAWASDFTFIRTHEGWMYLAVVIDLFSRQVVGWAMRDRADTELVVQALLSAVWRRKPSAGCLVHSDQGSVYTSDDWRSFLASHGLVCSMSRRGNCHEREACPWGTTHRWRASLVCSNASGSGGGSTPPRTPHAPRCSTTSRCSTTHNAVMVQLATCPL","length":268,"molWeight":30089,"crc64":"BF6564C7D472FD79","md5":"091EDCF2514D98A7F543DFB678E7808C"},"extraAttributes":{"countByFeatureType":{"Domain":1,"Region":1,"Binding site":2},"uniParcId":"UPI00000DA0A3"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q5BMV1","uniProtkbId":"Q5BMV1_XANCI","entryAudit":{"firstPublicDate":"2012-04-18","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2012-04-18","entryVersion":36,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24172.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24172.1"}],"value":"ISxac3 transposase"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24172.1"}],"value":"orf91"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009964"}],"value":"Belongs to the transposase 8 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Coiled coil","location":{"start":{"value":56,"modifier":"EXACT"},"end":{"value":83,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Coils"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Coils"}],"id":"KW-0175","category":"Domain","name":"Coiled coil"}],"references":[{"referenceNumber":1,"citation":{"id":"15755815","citationType":"journal article","authors":["Gillings M.R.","Holley M.P.","Stokes H.W.","Holmes A.J."],"citationCrossReferences":[{"database":"PubMed","id":"15755815"},{"database":"DOI","id":"10.1073/pnas.0406620102"}],"title":"Integrons in Xanthomonas: a source of species genome diversity.","publicationDate":"2005","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"4419","lastPage":"4424","volume":"102"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24172.1"}],"value":"DAR72029","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24181.1"}],"value":"DAR73889","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24172.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY928780","properties":[{"key":"ProteinId","value":"AAX24172.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY928783","properties":[{"key":"ProteinId","value":"AAX24181.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"Q5BMV1","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"APHFQQK","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"GO","id":"GO:0003677","properties":[{"key":"GoTerm","value":"F:DNA binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0004803","properties":[{"key":"GoTerm","value":"F:transposase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006313","properties":[{"key":"GoTerm","value":"P:DNA transposition"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"1.10.10.60","properties":[{"key":"EntryName","value":"Homeodomain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR009057","properties":[{"key":"EntryName","value":"Homeodomain-like_sf"}]},{"database":"InterPro","id":"IPR002514","properties":[{"key":"EntryName","value":"Transposase_8"}]},{"database":"PANTHER","id":"PTHR33215","properties":[{"key":"EntryName","value":"PROTEIN DISTAL ANTENNA"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33215:SF13","properties":[{"key":"EntryName","value":"PROTEIN DISTAL ANTENNA"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01527","properties":[{"key":"EntryName","value":"HTH_Tnp_1"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF46689","properties":[{"key":"EntryName","value":"Homeodomain-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSSKRYTDEFKIEAVRQVTDRGFKVAEVAERLGVTTHSLYAWLRKFGKPGVVQRAEADQSAEVRRLKIELRRVTEERDILKKAAAYFAKG","length":90,"molWeight":10358,"crc64":"C1EC5E1883E0D60F","md5":"654F270556C5D538CA874776E964D706"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Coiled coil":1},"uniParcId":"UPI00000DA0A4"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q5BMV3","uniProtkbId":"Q5BMV3_XANCI","entryAudit":{"firstPublicDate":"2005-04-12","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2005-04-12","entryVersion":58,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Xanthomonas citri","commonName":"Xanthomonas campestris pv. citri","taxonId":346,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24170.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Lysobacterales","Lysobacteraceae","Xanthomonas"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24170.1"}],"value":"Dihydroxy-acid dehydratase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24170.1"}],"value":"ilvD"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006486"}],"value":"Belongs to the IlvD/Edd family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":2,"modifier":"EXACT"},"end":{"value":108,"modifier":"EXACT"}},"description":"Dihydroxy-acid/6-phosphogluconate dehydratase C-terminal","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF24877"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24170.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023239"}],"id":"KW-0456","category":"Molecular function","name":"Lyase"}],"references":[{"referenceNumber":1,"citation":{"id":"15755815","citationType":"journal article","authors":["Gillings M.R.","Holley M.P.","Stokes H.W.","Holmes A.J."],"citationCrossReferences":[{"database":"PubMed","id":"15755815"},{"database":"DOI","id":"10.1073/pnas.0406620102"}],"title":"Integrons in Xanthomonas: a source of species genome diversity.","publicationDate":"2005","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"4419","lastPage":"4424","volume":"102"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24170.1"}],"value":"DAR65869","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24169.1"}],"value":"DAR65973","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24171.1"}],"value":"DAR72029","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24179.1"}],"value":"DAR73872","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24180.1"}],"value":"DAR73889","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAX24170.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY928778","properties":[{"key":"ProteinId","value":"AAX24169.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY928779","properties":[{"key":"ProteinId","value":"AAX24170.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY928780","properties":[{"key":"ProteinId","value":"AAX24171.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY928782","properties":[{"key":"ProteinId","value":"AAX24179.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY928783","properties":[{"key":"ProteinId","value":"AAX24180.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"Q5BMV3","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0016836","properties":[{"key":"GoTerm","value":"F:hydro-lyase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"Gene3D","id":"3.50.30.80","properties":[{"key":"EntryName","value":"IlvD/EDD C-terminal domain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR042096","properties":[{"key":"EntryName","value":"Dihydro-acid_dehy_C"}]},{"database":"InterPro","id":"IPR020558","properties":[{"key":"EntryName","value":"DiOHA_6PGluconate_deHydtase_CS"}]},{"database":"InterPro","id":"IPR056740","properties":[{"key":"EntryName","value":"ILV_EDD_C"}]},{"database":"PANTHER","id":"PTHR43661","properties":[{"key":"EntryName","value":"D-XYLONATE DEHYDRATASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR43661:SF3","properties":[{"key":"EntryName","value":"D-XYLONATE DEHYDRATASE YAGF-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF24877","properties":[{"key":"EntryName","value":"ILV_EDD_C"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52016","properties":[{"key":"EntryName","value":"LeuD/IlvD-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00887","properties":[{"key":"EntryName","value":"ILVD_EDD_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"YLKSKGLGKQCALLTDGRFSGGTSGLSIGHASPEAAAGGAIGLVREGDRILIDIPNRSINLLISDEELALRRAEQDAKGWKPVEVRPRKVTTALKAYALLATSADKGAVRDKALLDG","length":117,"molWeight":12282,"crc64":"2834B383E9A4CBCF","md5":"A1A0C53B78A592EE81FEA00C839C525A"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Domain":1,"Non-terminal residue":1},"uniParcId":"UPI00004EA66A"}}]}