{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"R9WQI3","uniProtkbId":"R9WQI3_MATTR","entryAudit":{"firstPublicDate":"2013-09-18","lastAnnotationUpdateDate":"2025-10-08","lastSequenceUpdateDate":"2013-09-18","entryVersion":20,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Matthiola tricuspidata","commonName":"Three-horned stock","synonyms":["Cheiranthus tricuspidatus"],"taxonId":309419,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGO01041.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Brassicales","Brassicaceae","Anchonieae","Matthiola"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGO01041.1"}],"value":"Putative progesterone 5-beta-reductase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGO01041.1"}],"value":"1.3.99.6"}]}]},"features":[{"type":"Domain","location":{"start":{"value":87,"modifier":"EXACT"},"end":{"value":387,"modifier":"EXACT"}},"description":"PRISE-like Rossmann-fold","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF22917"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022857"}],"id":"KW-0521","category":"Ligand","name":"NADP"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"},{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGO01041.1"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-A6HUTAL93IVPB","citationType":"submission","authors":["Costa C.","Mueller-Uri F.","Kreis W."],"publicationDate":"MAR-2013","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGO01041.1"}],"value":"Mature leaf","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGO01041.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KC757414","properties":[{"key":"ProteinId","value":"AGO01041.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"R9WQI3","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0047568","properties":[{"key":"GoTerm","value":"F:3-oxo-5-beta-steroid 4-dehydrogenase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0006629","properties":[{"key":"GoTerm","value":"P:lipid metabolic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd08948","properties":[{"key":"EntryName","value":"5beta-POR_like_SDR_a"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.40.50.720:FF:000808","properties":[{"key":"EntryName","value":"Iridoid synthase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.720","properties":[{"key":"EntryName","value":"NAD(P)-binding Rossmann-like Domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR036291","properties":[{"key":"EntryName","value":"NAD(P)-bd_dom_sf"}]},{"database":"InterPro","id":"IPR055222","properties":[{"key":"EntryName","value":"PRISE-like_Rossmann-fold"}]},{"database":"PANTHER","id":"PTHR32487","properties":[{"key":"EntryName","value":"3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR32487:SF0","properties":[{"key":"EntryName","value":"3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF22917","properties":[{"key":"EntryName","value":"PRISE"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF51735","properties":[{"key":"EntryName","value":"NAD(P)-binding Rossmann-fold domains"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSWWGAGAIGAAKKKLEEDEPTQSYESVALIIGVTGIVGNSLAEILPLSDTPGGPWKVYGVARRPRPSWNADHPIDYIQCDISDAEDARSKLSSLADVTHVFYVTWTNRPSEGENCEANGSMLRNVLQAIVPHAPNLRHVCLQTGTKHYLGPFDNLGKSHHDPPFTEDLPRLQIQNFYYTQEDILFEEIKKKEGVTWSVHRPNTIFGFSPYSLMNIVGTLCVYAAICKHQGSPLVFPGSKKAWEGFATASDADLIAEQQIGRLSIPMPRTRRLTATMPTSKWKHLWKVLAEQFGIKEYGFQEGKNLGLVEMMKGKDRVWEEMVKENQLQEMKLEEVAVWWFADVILGVEGMIDSMNKSKEHGFLGFRNSTNSFISWIDKYKAYKIVP","length":387,"molWeight":43652,"crc64":"E481CFD87FEFC617","md5":"4695F559BD589907F1EC7CB5D7B2EDF5"},"extraAttributes":{"countByFeatureType":{"Domain":1},"uniParcId":"UPI000352011C"}}]}