{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A223FQU7","uniProtkbId":"A0A223FQU7_ULMAM","entryAudit":{"firstPublicDate":"2017-10-25","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2017-10-25","entryVersion":14,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Ulmus americana","commonName":"American elm","taxonId":29740,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11580.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Rosales","Ulmaceae","Ulmus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11580.1"}],"value":"13S-lipoxygenase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11580.1"}],"value":"13S-LOX"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"value":"Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"value":"Lipid metabolism; oxylipin biosynthesis"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":354,"modifier":"EXACT"}},"description":"Lipoxygenase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51393"}]},{"type":"Binding site","location":{"start":{"value":333,"modifier":"EXACT"},"end":{"value":333,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600907-1"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875","note":"catalytic"}},{"type":"Binding site","location":{"start":{"value":338,"modifier":"EXACT"},"end":{"value":338,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600907-1"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875","note":"catalytic"}},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11580.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":354,"modifier":"EXACT"},"end":{"value":354,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11580.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022964"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0223","category":"Molecular function","name":"Dioxygenase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0275","category":"Biological process","name":"Fatty acid biosynthesis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0276","category":"Biological process","name":"Fatty acid metabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600907-1"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0444","category":"Biological process","name":"Lipid biosynthesis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0443","category":"Biological process","name":"Lipid metabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600907-1"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0925","category":"Biological process","name":"Oxylipin biosynthesis"}],"references":[{"referenceNumber":1,"citation":{"id":"28769110","citationType":"journal article","authors":["Sherif S.M.","Erland L.A.","Shukla M.R.","Saxena P.K."],"citationCrossReferences":[{"database":"PubMed","id":"28769110"}],"title":"Bark and wood tissues of American elm exhibit distinct responses to Dutch elm disease.","publicationDate":"2017","journal":"Sci. Rep.","firstPage":"7114","lastPage":"7114","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11580.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KY866673","properties":[{"key":"ProteinId","value":"AST11580.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A223FQU7","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0016165","properties":[{"key":"GoTerm","value":"F:linoleate 13S-lipoxygenase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0046872","properties":[{"key":"GoTerm","value":"F:metal ion binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006633","properties":[{"key":"GoTerm","value":"P:fatty acid biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0034440","properties":[{"key":"GoTerm","value":"P:lipid oxidation"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0031408","properties":[{"key":"GoTerm","value":"P:oxylipin biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"FunFam","id":"3.10.450.60:FF:000005","properties":[{"key":"EntryName","value":"Lipoxygenase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.10.450.60","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"4.10.375.10","properties":[{"key":"EntryName","value":"Lipoxygenase-1, Domain 2"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"4.10.372.10","properties":[{"key":"EntryName","value":"Lipoxygenase-1, Domain 3"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.245.10","properties":[{"key":"EntryName","value":"Lipoxygenase-1, Domain 5"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR000907","properties":[{"key":"EntryName","value":"LipOase"}]},{"database":"InterPro","id":"IPR013819","properties":[{"key":"EntryName","value":"LipOase_C"}]},{"database":"InterPro","id":"IPR036226","properties":[{"key":"EntryName","value":"LipOase_C_sf"}]},{"database":"InterPro","id":"IPR001246","properties":[{"key":"EntryName","value":"LipOase_plant"}]},{"database":"InterPro","id":"IPR027433","properties":[{"key":"EntryName","value":"Lipoxygenase_dom_3"}]},{"database":"PANTHER","id":"PTHR11771","properties":[{"key":"EntryName","value":"LIPOXYGENASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00305","properties":[{"key":"EntryName","value":"Lipoxygenase"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00087","properties":[{"key":"EntryName","value":"LIPOXYGENASE"}]},{"database":"PRINTS","id":"PR00468","properties":[{"key":"EntryName","value":"PLTLPOXGNASE"}]},{"database":"SUPFAM","id":"SSF48484","properties":[{"key":"EntryName","value":"Lipoxigenase"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51393","properties":[{"key":"EntryName","value":"LIPOXYGENASE_3"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"ILRGNGEGERKHFERIYDYDVYNDIGDPDKNLKLQRPAFGGEELPYPRRCRTGRPRCESDSMSEKRNGRRFYVPRDECFSEIKQLTFQAKTLYSVLHALSPSLATAMADRELGFPHFTTIDALFCEGVDLPPIGNEGFLRSVLPRVVKTFKDTGKDVLRFEPPETINRDKFFWFRDQEFARQTLAGLNPCGIRLITEWPLKSKLDPEIYGPPESAITTEMIEQEIGGIMSVDQAIKQKKLFILDHHDVLLPFVHKVRKIKGTTLYGSRAVFFLNPDGTLRPLAIELTRPKSDEKPQWKQAFTPSWHSTSIWLWRIAKVHVLAHDSGYHQLVSHWLKTHAVTEPYVIATNRQLSV","length":354,"molWeight":40777,"crc64":"9983740784A8F487","md5":"0F511364682C3991FC2BCF133A44C6BE"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"PATHWAY":1,"CAUTION":1},"countByFeatureType":{"Domain":1,"Binding site":2,"Non-terminal residue":2},"uniParcId":"UPI000B99FB26"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A223FQV4","uniProtkbId":"A0A223FQV4_ULMAM","entryAudit":{"firstPublicDate":"2017-10-25","lastAnnotationUpdateDate":"2025-04-02","lastSequenceUpdateDate":"2017-10-25","entryVersion":18,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Ulmus americana","commonName":"American elm","taxonId":29740,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11582.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Rosales","Ulmaceae","Ulmus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012209"}],"value":"allene-oxide cyclase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012209"}],"value":"5.3.99.6"}]},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11582.1"}],"value":"AOC"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"(9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate = (9S,13S,15Z)-12-oxophyto-10,15-dienoate","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:22592"},{"database":"ChEBI","id":"CHEBI:36438"},{"database":"ChEBI","id":"CHEBI:57411"}],"ecNumber":"5.3.99.6","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00049891"}]}},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004229"}],"value":"Plastid, chloroplast","id":"SL-0049"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00007982"}],"value":"Belongs to the allene oxide cyclase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11582.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":101,"modifier":"EXACT"},"end":{"value":101,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11582.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022528"}],"id":"KW-0150","category":"Cellular component","name":"Chloroplast"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023235"}],"id":"KW-0413","category":"Molecular function","name":"Isomerase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022640"}],"id":"KW-0934","category":"Cellular component","name":"Plastid"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022946"}],"id":"KW-0809","category":"Domain","name":"Transit peptide"}],"references":[{"referenceNumber":1,"citation":{"id":"28769110","citationType":"journal article","authors":["Sherif S.M.","Erland L.A.","Shukla M.R.","Saxena P.K."],"citationCrossReferences":[{"database":"PubMed","id":"28769110"}],"title":"Bark and wood tissues of American elm exhibit distinct responses to Dutch elm disease.","publicationDate":"2017","journal":"Sci. Rep.","firstPage":"7114","lastPage":"7114","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11582.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KY866675","properties":[{"key":"ProteinId","value":"AST11582.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A223FQV4","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0009507","properties":[{"key":"GoTerm","value":"C:chloroplast"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0046423","properties":[{"key":"GoTerm","value":"F:allene-oxide cyclase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0009695","properties":[{"key":"GoTerm","value":"P:jasmonic acid biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"2.40.480.10","properties":[{"key":"EntryName","value":"Allene oxide cyclase-like"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR009410","properties":[{"key":"EntryName","value":"Allene_ox_cyc"}]},{"database":"InterPro","id":"IPR044859","properties":[{"key":"EntryName","value":"Allene_oxi_cyc_Dirigent"}]},{"database":"InterPro","id":"IPR034871","properties":[{"key":"EntryName","value":"Allene_oxi_cyc_sf"}]},{"database":"PANTHER","id":"PTHR31843","properties":[{"key":"EntryName","value":"ALLENE OXIDE CYCLASE 4, CHLOROPLASTIC"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR31843:SF11","properties":[{"key":"EntryName","value":"ALLENE OXIDE CYCLASE 4, CHLOROPLASTIC"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF06351","properties":[{"key":"EntryName","value":"Allene_ox_cyc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF141493","properties":[{"key":"EntryName","value":"Allene oxide cyclase-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"IYTGDLQKRLGITAGMCILIENKPEKKGDRYEAIFSFYFGDYGHISVQGPYLTYEDSCLTVTGGTGIFEGAYGEVKLHQIVFPFKIFYSFYLKGIGDLPSE","length":101,"molWeight":11339,"crc64":"9B55EB7DCE6E14E5","md5":"F76E14196B547E64716CE5BFFD18119D"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI000B9A04FF"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"O24420","uniProtkbId":"O24420_ULMAM","entryAudit":{"firstPublicDate":"1998-01-01","lastAnnotationUpdateDate":"2025-02-05","lastSequenceUpdateDate":"1998-01-01","entryVersion":58,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Ulmus americana","commonName":"American elm","taxonId":29740,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAB71731.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Rosales","Ulmaceae","Ulmus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"value":"Acyl-[acyl-carrier-protein] hydrolase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"value":"3.1.2.-"}]},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAB71731.1"}],"value":"Ua-FatB1"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"value":"Plays an essential role in chain termination during de novo fatty acid synthesis"}],"commentType":"FUNCTION"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004229"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"value":"Plastid, chloroplast","id":"SL-0049"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006500"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"value":"Belongs to the acyl-ACP thioesterase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":2,"modifier":"EXACT"},"end":{"value":85,"modifier":"EXACT"}},"description":"Acyl-ACP-thioesterase N-terminal","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF12590"}]},{"type":"Domain","location":{"start":{"value":96,"modifier":"EXACT"},"end":{"value":231,"modifier":"EXACT"}},"description":"Acyl-ACP thioesterase N-terminal hotdog","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF01643"}]},{"type":"Domain","location":{"start":{"value":260,"modifier":"EXACT"},"end":{"value":359,"modifier":"EXACT"}},"description":"Acyl-ACP thioesterase-like C-terminal","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF20791"}]},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":22,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":8,"modifier":"EXACT"},"end":{"value":22,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAB71731.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022528"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"id":"KW-0150","category":"Cellular component","name":"Chloroplast"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023160"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"id":"KW-0275","category":"Biological process","name":"Fatty acid biosynthesis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022832"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"id":"KW-0276","category":"Biological process","name":"Fatty acid metabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022801"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022516"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"id":"KW-0444","category":"Biological process","name":"Lipid biosynthesis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023098"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"id":"KW-0443","category":"Biological process","name":"Lipid metabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022640"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363096"}],"id":"KW-0934","category":"Cellular component","name":"Plastid"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022946"}],"id":"KW-0809","category":"Domain","name":"Transit peptide"}],"references":[{"referenceNumber":1,"citation":{"id":"9193098","citationType":"journal article","authors":["Voelker T.A.","Jones A.","Cranmer A.M.","Davies H.M.","Knutzon D.S."],"citationCrossReferences":[{"database":"PubMed","id":"9193098"},{"database":"DOI","id":"10.1104/pp.114.2.669"}],"title":"Broad-range and binary-range acyl-acyl-carrier protein thioesterases suggest an alternative mechanism for medium-chain production in seeds.","publicationDate":"1997","journal":"Plant Physiol.","firstPage":"669","lastPage":"677","volume":"114"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAB71731.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"U65644","properties":[{"key":"ProteinId","value":"AAB71731.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"GO","id":"GO:0009507","properties":[{"key":"GoTerm","value":"C:chloroplast"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0000036","properties":[{"key":"GoTerm","value":"F:acyl carrier activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0016297","properties":[{"key":"GoTerm","value":"F:fatty acyl-[ACP] hydrolase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd00586","properties":[{"key":"EntryName","value":"4HBT"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.10.129.10:FF:000014","properties":[{"key":"EntryName","value":"Acyl-[acyl-carrier-protein] hydrolase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.10.129.10","properties":[{"key":"EntryName","value":"Hotdog Thioesterase"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR021113","properties":[{"key":"EntryName","value":"Acyl-ACP-thioesterase_N"}]},{"database":"InterPro","id":"IPR049427","properties":[{"key":"EntryName","value":"Acyl-ACP_TE_C"}]},{"database":"InterPro","id":"IPR002864","properties":[{"key":"EntryName","value":"Acyl-ACP_thioesterase_NHD"}]},{"database":"InterPro","id":"IPR045023","properties":[{"key":"EntryName","value":"FATA/B"}]},{"database":"InterPro","id":"IPR029069","properties":[{"key":"EntryName","value":"HotDog_dom_sf"}]},{"database":"PANTHER","id":"PTHR31727","properties":[{"key":"EntryName","value":"OLEOYL-ACYL CARRIER PROTEIN THIOESTERASE 1, CHLOROPLASTIC"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR31727:SF2","properties":[{"key":"EntryName","value":"PALMITOYL-ACYL CARRIER PROTEIN THIOESTERASE, CHLOROPLASTIC"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01643","properties":[{"key":"EntryName","value":"Acyl-ACP_TE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF20791","properties":[{"key":"EntryName","value":"Acyl-ACP_TE_C"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF12590","properties":[{"key":"EntryName","value":"Acyl-thio_N"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF54637","properties":[{"key":"EntryName","value":"Thioesterase/thiol ester dehydrase-isomerase"},{"key":"MatchStatus","value":"2"}]}],"sequence":{"value":"GSGALQVKASSQAPPKLNGSNVGLVKSSQIVKKGDDTTSPPARTFINQLPDWSMLLAAITTLFLAAEKQWMMLDWKPKRPDMLVDPFGLGRFVQDGLVFRNNFSIRSYEIGADRTASIETLMNHLQETALNHVKSVGLLEDGLGSTREMSLRNLIWVVTKMQVAVDRYPTWGDEVQVSSWATAIGKNGMRREWIVTDFRTGETLLRATSVWVMMNKLTRRISKIPEEVWHEIGPSFIDAPPLPTVEDDGRKLTRFDESSADFIRXGLTPRWSDLDINQHVNNVKYIGWLLESAPPEIHESHEIASLTLEYRRECGRDSVLNSATKVSDSSQLGKSAVECNHLVRLQNGGEIVKGRTVWRPKRPLYNDGAVVDVXAKTS","length":378,"molWeight":42304,"crc64":"EE333663179DF6FD","md5":"7A1FF3470194A9706FA5B2EB94A2BA2B"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Domain":3,"Region":1,"Compositional bias":1,"Non-terminal residue":1},"uniParcId":"UPI00000A9E3C"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q43853","uniProtkbId":"Q43853_ULMAM","entryAudit":{"firstPublicDate":"1996-11-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1996-11-01","entryVersion":115,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Ulmus americana","commonName":"American elm","taxonId":29740,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAA34214.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Rosales","Ulmaceae","Ulmus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAA34214.1"}],"value":"Chitinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAA34214.1"}],"value":"3.2.1.14"}]}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAA34214.1"}],"value":"pHS2"},"synonyms":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82487.1"}],"value":"CHT"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009373"}],"value":"Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":21,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":22,"modifier":"EXACT"},"end":{"value":321,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5007702690"},{"type":"Domain","location":{"start":{"value":21,"modifier":"EXACT"},"end":{"value":62,"modifier":"EXACT"}},"description":"Chitin-binding type-1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50941"}]},{"type":"Active site","location":{"start":{"value":135,"modifier":"EXACT"},"end":{"value":135,"modifier":"EXACT"}},"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR001060-1"}]},{"type":"Disulfide bond","location":{"start":{"value":24,"modifier":"EXACT"},"end":{"value":39,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR001060-2"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":33,"modifier":"EXACT"},"end":{"value":45,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR001060-2"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":38,"modifier":"EXACT"},"end":{"value":52,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR001060-2"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":56,"modifier":"EXACT"},"end":{"value":60,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR001060-2"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":167,"modifier":"EXACT"},"end":{"value":175,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR001060-2"}]},{"type":"Disulfide bond","location":{"start":{"value":274,"modifier":"EXACT"},"end":{"value":306,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR001060-2"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022669"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}],"id":"KW-0147","category":"Ligand","name":"Chitin-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023157"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR001060-2"}],"id":"KW-1015","category":"PTM","name":"Disulfide bond"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAA34214.1"}],"id":"KW-0326","category":"Molecular function","name":"Glycosidase"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAA34214.1"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022821"}],"id":"KW-0611","category":"Biological process","name":"Plant defense"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-B1UE4158O4MEO","citationType":"submission","authors":["Hajela R.K.","Graham L.S.","Sherald J.L.","Sticklen M.B."],"title":"Nucleotide sequence of a cDNA encoding a chitinase-like polypeptide from Dutch elm disease-resistant elm selection NPS 3-487.","publicationDate":"NOV-1993","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAA34214.1"}],"value":"Callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAA34214.1"}]},{"referenceNumber":2,"citation":{"id":"CI-BORAQ9O71APL1","citationType":"submission","authors":["Nasmith C.G.","Jeng R.S.","Hubbes M."],"title":"Comparison of steady state targeted gene expression in Ulmus americana and U. pumila tissues.","publicationDate":"MAY-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82487.1"}]},{"referenceNumber":3,"citation":{"id":"CI-16FL7VLO633EQ","citationType":"journal article","authors":["Nasmith C.","Jeng R.","Hubbes M."],"citationCrossReferences":[{"database":"DOI","id":"10.1111/j.1439-0329.2007.00523.x"}],"title":"Targeted gene analysis in Ulmus americana and U. pumila tissues.","publicationDate":"2008","journal":"For. Pathol.","firstPage":"90","lastPage":"103","volume":"38"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82487.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"L22032","properties":[{"key":"ProteinId","value":"AAA34214.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"DQ078281","properties":[{"key":"ProteinId","value":"AAY82487.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"Q43853","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0008061","properties":[{"key":"GoTerm","value":"F:chitin binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0008843","properties":[{"key":"GoTerm","value":"F:endochitinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0005975","properties":[{"key":"GoTerm","value":"P:carbohydrate metabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016998","properties":[{"key":"GoTerm","value":"P:cell wall macromolecule catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006032","properties":[{"key":"GoTerm","value":"P:chitin catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0050832","properties":[{"key":"GoTerm","value":"P:defense response to fungus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd00325","properties":[{"key":"EntryName","value":"chitinase_GH19"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd06921","properties":[{"key":"EntryName","value":"ChtBD1_GH19_hevein"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.60.10:FF:000001","properties":[{"key":"EntryName","value":"Basic endochitinase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.20.10:FF:000001","properties":[{"key":"EntryName","value":"Endochitinase (Chitinase)"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.530.10","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.20.10","properties":[{"key":"EntryName","value":"Endochitinase, domain 2"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.60.10","properties":[{"key":"EntryName","value":"Endochitinase-like"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR001002","properties":[{"key":"EntryName","value":"Chitin-bd_1"}]},{"database":"InterPro","id":"IPR018371","properties":[{"key":"EntryName","value":"Chitin-binding_1_CS"}]},{"database":"InterPro","id":"IPR036861","properties":[{"key":"EntryName","value":"Endochitinase-like_sf"}]},{"database":"InterPro","id":"IPR016283","properties":[{"key":"EntryName","value":"Glyco_hydro_19"}]},{"database":"InterPro","id":"IPR000726","properties":[{"key":"EntryName","value":"Glyco_hydro_19_cat"}]},{"database":"InterPro","id":"IPR023346","properties":[{"key":"EntryName","value":"Lysozyme-like_dom_sf"}]},{"database":"PANTHER","id":"PTHR22595","properties":[{"key":"EntryName","value":"CHITINASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR22595:SF200","properties":[{"key":"EntryName","value":"ENDOCHITINASE 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00187","properties":[{"key":"EntryName","value":"Chitin_bind_1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00182","properties":[{"key":"EntryName","value":"Glyco_hydro_19"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF001060","properties":[{"key":"EntryName","value":"Endochitinase"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00451","properties":[{"key":"EntryName","value":"CHITINBINDNG"}]},{"database":"SMART","id":"SM00270","properties":[{"key":"EntryName","value":"ChtBD1"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF53955","properties":[{"key":"EntryName","value":"Lysozyme-like"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF57016","properties":[{"key":"EntryName","value":"Plant lectins/antimicrobial peptides"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00026","properties":[{"key":"EntryName","value":"CHIT_BIND_I_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50941","properties":[{"key":"EntryName","value":"CHIT_BIND_I_2"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00774","properties":[{"key":"EntryName","value":"CHITINASE_19_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MRFWALTTLSLLLSIIQGGWAEQCGSQAGGAVCPVGLCCSKFGWCGSTNEYCGDGCQSQCGGTGRGDIGGLISSSAFNDMLKHRNDRWFPAKGFYTYDAFISGLSKAFPCNLRTTGDDITRKREIAAFLGQTSHETTGGWASAPRGPITLGGYCYNREPKTLLLDYCSFSPTWPCASGKRYFGRGPIQLSWNYNYGQCGRRIGANLLNNPDLVATDPVISFKTALWFWMTPQSPKPSCHDVITGRWSPSGTDQSAGRVAGYGVITNIINGGIECGKGQVPQVVERIGFYKRYCDILIVGYGNNLDCYNQRPFGNGLLLDTM","length":321,"molWeight":34951,"crc64":"C7FEFF2FEE313C51","md5":"903E120043BFFF5D2DE6BE7DA1B312A7"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Signal":1,"Chain":1,"Domain":1,"Active site":1,"Disulfide bond":6},"uniParcId":"UPI00000A2165"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q4PJW1","uniProtkbId":"Q4PJW1_ULMAM","entryAudit":{"firstPublicDate":"2005-07-19","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2005-07-19","entryVersion":95,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Ulmus americana","commonName":"American elm","taxonId":29740,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82485.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Rosales","Ulmaceae","Ulmus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012139"}],"value":"phenylalanine ammonia-lyase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012139"}],"value":"4.3.1.24"}]},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82485.1"}],"value":"PAL"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00002235"}],"value":"This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-phenylalanine = (E)-cinnamate + NH4(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:21384"},{"database":"ChEBI","id":"CHEBI:15669"},{"database":"ChEBI","id":"CHEBI:28938"},{"database":"ChEBI","id":"CHEBI:58095"}],"ecNumber":"4.3.1.24","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023537"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00005138"}],"value":"Phenylpropanoid metabolism; trans-cinnamate biosynthesis; trans-cinnamate from L-phenylalanine: step 1/1"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00011881"}],"value":"Homotetramer"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004496"}],"value":"Cytoplasm","id":"SL-0086"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00007238"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003954"}],"value":"Belongs to the PAL/histidase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82485.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022490"}],"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023239"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003954"}],"id":"KW-0456","category":"Molecular function","name":"Lyase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023232"}],"id":"KW-0585","category":"Biological process","name":"Phenylalanine catabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023051"}],"id":"KW-0587","category":"Biological process","name":"Phenylpropanoid metabolism"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-BORAQ9O71APL1","citationType":"submission","authors":["Nasmith C.G.","Jeng R.S.","Hubbes M."],"title":"Comparison of steady state targeted gene expression in Ulmus americana and U. pumila tissues.","publicationDate":"MAY-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82485.1"}]},{"referenceNumber":2,"citation":{"id":"CI-16FL7VLO633EQ","citationType":"journal article","authors":["Nasmith C.","Jeng R.","Hubbes M."],"citationCrossReferences":[{"database":"DOI","id":"10.1111/j.1439-0329.2007.00523.x"}],"title":"Targeted gene analysis in Ulmus americana and U. pumila tissues.","publicationDate":"2008","journal":"For. Pathol.","firstPage":"90","lastPage":"103","volume":"38"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82485.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ078279","properties":[{"key":"ProteinId","value":"AAY82485.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"Q4PJW1","properties":[{"key":"Description","value":"-"}]},{"database":"UniPathway","id":"UPA00713","properties":[{"key":"RectionId","value":"UER00725"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0045548","properties":[{"key":"GoTerm","value":"F:phenylalanine ammonia-lyase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0009800","properties":[{"key":"GoTerm","value":"P:cinnamic acid biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniPathway"}]},{"database":"GO","id":"GO:0006559","properties":[{"key":"GoTerm","value":"P:L-phenylalanine catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd00332","properties":[{"key":"EntryName","value":"PAL-HAL"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.20.200.10:FF:000009","properties":[{"key":"EntryName","value":"Phenylalanine ammonia-lyase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.200.10","properties":[{"key":"EntryName","value":"Fumarase/aspartase (Central domain)"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.275.10","properties":[{"key":"EntryName","value":"Fumarase/aspartase (N-terminal domain)"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.274.20","properties":[{"key":"EntryName","value":"Phenylalanine ammonia-lyase 1, domain 3"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR001106","properties":[{"key":"EntryName","value":"Aromatic_Lyase"}]},{"database":"InterPro","id":"IPR024083","properties":[{"key":"EntryName","value":"Fumarase/histidase_N"}]},{"database":"InterPro","id":"IPR008948","properties":[{"key":"EntryName","value":"L-Aspartase-like"}]},{"database":"InterPro","id":"IPR005922","properties":[{"key":"EntryName","value":"Phe_NH3-lyase"}]},{"database":"InterPro","id":"IPR023144","properties":[{"key":"EntryName","value":"Phe_NH3-lyase_shielding_dom_sf"}]},{"database":"NCBIfam","id":"TIGR01226","properties":[{"key":"EntryName","value":"phe_am_lyase"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10362","properties":[{"key":"EntryName","value":"HISTIDINE AMMONIA-LYASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00221","properties":[{"key":"EntryName","value":"Lyase_aromatic"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF48557","properties":[{"key":"EntryName","value":"L-aspartase-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"PLSYIAGLMTGRPNSKAVGPNGDIISPTEAFNLAGITSGFFELQPKEGIAMVNGTAVGSGLASVVLFDANVLAILSELLSAIFAEVMLGKPEFTDHLTHKLKHHPGQIEAAAIMEHIFDGSSYIKDAQKVHEIDPLQKPKKDRYALITSPQWLGPQIEVIRAATKMIEREINSVDDNPLIDVSRNKALHGRNFQGTPIGVSMDNTRLAIASIGKLMFAQFSELVNDFYNKGLPSNLSGGRNPSWDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTEEAVEILKLMSTTFLVALCQAIDLRHLEENLKNTVKNTVSQVAKKVLTTGSNGELHPSRLCEKDLLKVVDREYVFSYIDDPCSSIYPLMQELRQVLVDHALNNGEKETNPNTSIFQKIAAFEEELKTLLPKEVESSRVQLENGNPAIPDKIKGCRSFPLYKFVREELGTGLLTGEKVKSPGEEFDKVFPAMCAGKLIDPLLECLKEWDGAPLPIC","length":509,"molWeight":55931,"crc64":"5E840BA636C1F11A","md5":"9E1E3BFCB433572DC79E28CB3786266C"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"PATHWAY":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Non-terminal residue":1},"uniParcId":"UPI0000538873"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A223FQT9","uniProtkbId":"A0A223FQT9_ULMAM","entryAudit":{"firstPublicDate":"2017-10-25","lastAnnotationUpdateDate":"2025-02-05","lastSequenceUpdateDate":"2017-10-25","entryVersion":12,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Ulmus americana","commonName":"American elm","taxonId":29740,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11581.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Rosales","Ulmaceae","Ulmus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11581.1"}],"value":"Allene oxide synthase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11581.1"}],"value":"AOS"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00010617"}],"value":"Belongs to the cytochrome P450 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11581.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":140,"modifier":"EXACT"},"end":{"value":140,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11581.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"}],"references":[{"referenceNumber":1,"citation":{"id":"28769110","citationType":"journal article","authors":["Sherif S.M.","Erland L.A.","Shukla M.R.","Saxena P.K."],"citationCrossReferences":[{"database":"PubMed","id":"28769110"}],"title":"Bark and wood tissues of American elm exhibit distinct responses to Dutch elm disease.","publicationDate":"2017","journal":"Sci. Rep.","firstPage":"7114","lastPage":"7114","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11581.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KY866674","properties":[{"key":"ProteinId","value":"AST11581.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A223FQT9","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0020037","properties":[{"key":"GoTerm","value":"F:heme binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0005506","properties":[{"key":"GoTerm","value":"F:iron ion binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0004497","properties":[{"key":"GoTerm","value":"F:monooxygenase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016705","properties":[{"key":"GoTerm","value":"F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016125","properties":[{"key":"GoTerm","value":"P:sterol metabolic process"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"Gene3D","id":"1.10.630.10","properties":[{"key":"EntryName","value":"Cytochrome P450"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR001128","properties":[{"key":"EntryName","value":"Cyt_P450"}]},{"database":"InterPro","id":"IPR036396","properties":[{"key":"EntryName","value":"Cyt_P450_sf"}]},{"database":"PANTHER","id":"PTHR24286:SF302","properties":[{"key":"EntryName","value":"ALLENE OXIDE SYNTHASE 2"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR24286","properties":[{"key":"EntryName","value":"CYTOCHROME P450 26"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00067","properties":[{"key":"EntryName","value":"p450"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF48264","properties":[{"key":"EntryName","value":"Cytochrome P450"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"KSVAYEVLRIEPPVPFQYGNAKEDIVVESHDASFKIKKGEMVFGFQPFATRDPKVFDKAEDFVADRFVGLGEKLLKYVFWSNGRESDKPTADNKQCPGRDLVVLVARVVLVEFFLRYDTFEVEDKLFLVGSKVTFKSLTK","length":140,"molWeight":16005,"crc64":"1EB11C8A32479AD8","md5":"5FBC1EF351EA772A0836C3540B6EA593"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI000B99F848"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A223FQV3","uniProtkbId":"A0A223FQV3_ULMAM","entryAudit":{"firstPublicDate":"2017-10-25","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2017-10-25","entryVersion":9,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Ulmus americana","commonName":"American elm","taxonId":29740,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11583.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Rosales","Ulmaceae","Ulmus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11583.1"}],"value":"OPDA-reductase 3"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11583.1"}],"value":"OPR3"}}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11583.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":75,"modifier":"EXACT"},"end":{"value":75,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11583.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022630"}],"id":"KW-0285","category":"Ligand","name":"Flavoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022643"}],"id":"KW-0288","category":"Ligand","name":"FMN"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022857"}],"id":"KW-0521","category":"Ligand","name":"NADP"}],"references":[{"referenceNumber":1,"citation":{"id":"28769110","citationType":"journal article","authors":["Sherif S.M.","Erland L.A.","Shukla M.R.","Saxena P.K."],"citationCrossReferences":[{"database":"PubMed","id":"28769110"}],"title":"Bark and wood tissues of American elm exhibit distinct responses to Dutch elm disease.","publicationDate":"2017","journal":"Sci. Rep.","firstPage":"7114","lastPage":"7114","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11583.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KY866676","properties":[{"key":"ProteinId","value":"AST11583.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A223FQV3","properties":[{"key":"Description","value":"-"}]},{"database":"Gene3D","id":"3.20.20.70","properties":[{"key":"EntryName","value":"Aldolase class I"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR013785","properties":[{"key":"EntryName","value":"Aldolase_TIM"}]},{"database":"InterPro","id":"IPR045247","properties":[{"key":"EntryName","value":"Oye-like"}]},{"database":"PANTHER","id":"PTHR22893","properties":[{"key":"EntryName","value":"NADH OXIDOREDUCTASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR22893:SF91","properties":[{"key":"EntryName","value":"NADPH DEHYDROGENASE 2-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF51395","properties":[{"key":"EntryName","value":"FMN-linked oxidoreductases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"STSHKETSIGPFVAYGRLFLANPKLPKRFVFDDPLNKYNRETFYTSVFSLHISYLSFGQLVVKTFPHVRFSRFVG","length":75,"molWeight":8705,"crc64":"11C400C63CF20390","md5":"4A99C1934794F1297717247195C8118B"},"extraAttributes":{"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI000B9A0782"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A223FQV7","uniProtkbId":"A0A223FQV7_ULMAM","entryAudit":{"firstPublicDate":"2017-10-25","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2017-10-25","entryVersion":22,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Ulmus americana","commonName":"American elm","taxonId":29740,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11584.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Rosales","Ulmaceae","Ulmus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11584.1"}],"value":"JA-methyltransferase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11584.1"}],"value":"JMT"}}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11584.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":213,"modifier":"EXACT"},"end":{"value":213,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11584.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11584.1"}],"id":"KW-0489","category":"Molecular function","name":"Methyltransferase"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11584.1"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"28769110","citationType":"journal article","authors":["Sherif S.M.","Erland L.A.","Shukla M.R.","Saxena P.K."],"citationCrossReferences":[{"database":"PubMed","id":"28769110"}],"title":"Bark and wood tissues of American elm exhibit distinct responses to Dutch elm disease.","publicationDate":"2017","journal":"Sci. Rep.","firstPage":"7114","lastPage":"7114","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11584.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KY866677","properties":[{"key":"ProteinId","value":"AST11584.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A223FQV7","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0008168","properties":[{"key":"GoTerm","value":"F:methyltransferase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.40.50.150","properties":[{"key":"EntryName","value":"Vaccinia Virus protein VP39"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR005299","properties":[{"key":"EntryName","value":"MeTrfase_7"}]},{"database":"InterPro","id":"IPR029063","properties":[{"key":"EntryName","value":"SAM-dependent_MTases_sf"}]},{"database":"PANTHER","id":"PTHR31009","properties":[{"key":"EntryName","value":"S-ADENOSYL-L-METHIONINE:CARBOXYL METHYLTRANSFERASE FAMILY PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03492","properties":[{"key":"EntryName","value":"Methyltransf_7"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF53335","properties":[{"key":"EntryName","value":"S-adenosyl-L-methionine-dependent methyltransferases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"SFYGRVFPKKSLHFVHSSSSLHWLSQVPSGLDINSKTPLNKGKLYISKSSPQSVLDAYSVQFQKDFSSFLRCRSQEIVEGGLMVLAFMGRSSSDPTTEESCYQWELLARALMTMVSEGLIEEEKVDSFNAPYYAPSPEEVKLEIEKEGSFILERLEAYEVDWDGGAADVEIMGGGTVAKLSRGQKVAKTIRAVVESMLEAHFGKDAVIMDDLF","length":213,"molWeight":23695,"crc64":"50C324B868F1D463","md5":"5D68D054454BFFA5E342CB70E22ADAB4"},"extraAttributes":{"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI000B9A0C51"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A223FQW0","uniProtkbId":"A0A223FQW0_ULMAM","entryAudit":{"firstPublicDate":"2017-10-25","lastAnnotationUpdateDate":"2025-04-02","lastSequenceUpdateDate":"2017-10-25","entryVersion":12,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Ulmus americana","commonName":"American elm","taxonId":29740,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11585.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Rosales","Ulmaceae","Ulmus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11585.1"}],"value":"JA-resistance"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11585.1"}],"value":"JAR"}}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11585.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":111,"modifier":"EXACT"},"end":{"value":111,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11585.1"}]}],"references":[{"referenceNumber":1,"citation":{"id":"28769110","citationType":"journal article","authors":["Sherif S.M.","Erland L.A.","Shukla M.R.","Saxena P.K."],"citationCrossReferences":[{"database":"PubMed","id":"28769110"}],"title":"Bark and wood tissues of American elm exhibit distinct responses to Dutch elm disease.","publicationDate":"2017","journal":"Sci. Rep.","firstPage":"7114","lastPage":"7114","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AST11585.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KY866678","properties":[{"key":"ProteinId","value":"AST11585.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A223FQW0","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0016881","properties":[{"key":"GoTerm","value":"F:acid-amino acid ligase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"InterPro","id":"IPR004993","properties":[{"key":"EntryName","value":"GH3"}]},{"database":"PANTHER","id":"PTHR31901","properties":[{"key":"EntryName","value":"GH3 DOMAIN-CONTAINING PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR31901:SF5","properties":[{"key":"EntryName","value":"JASMONOYL--L-AMINO ACID SYNTHETASE JAR1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03321","properties":[{"key":"EntryName","value":"GH3"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"LVHFFFCREFPISNGKALNFIYSSKQFETKGGLAAGTATTNVFRNSEYKKTMKAFQSQCCSPDEVIFGPDFHQSLYCHFLCGLIFREDVQLISSTFAHSIVHAFRTFEKVW","length":111,"molWeight":12749,"crc64":"619592F942AF6453","md5":"282C31DD1DFB3C654CE255CC368F9325"},"extraAttributes":{"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI000B9A1684"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q4PJV7","uniProtkbId":"Q4PJV7_ULMAM","entryAudit":{"firstPublicDate":"2005-07-19","lastAnnotationUpdateDate":"2025-10-08","lastSequenceUpdateDate":"2005-07-19","entryVersion":39,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Ulmus americana","commonName":"American elm","taxonId":29740,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82489.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Rosales","Ulmaceae","Ulmus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82489.1"}],"value":"Polygalacturonase inhibiting protein"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82489.1"}],"value":"PGIP"}}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004370"}],"value":"Membrane","id":"SL-0162"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004191"}],"value":"Secreted, cell wall","id":"SL-0041"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00038043"}],"value":"Belongs to the polygalacturonase-inhibiting protein family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82489.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022512"}],"id":"KW-0134","category":"Cellular component","name":"Cell wall"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022614"}],"id":"KW-0433","category":"Domain","name":"Leucine-rich repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022512"}],"id":"KW-0964","category":"Cellular component","name":"Secreted"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"}],"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-BORAQ9O71APL1","citationType":"submission","authors":["Nasmith C.G.","Jeng R.S.","Hubbes M."],"title":"Comparison of steady state targeted gene expression in Ulmus americana and U. pumila tissues.","publicationDate":"MAY-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82489.1"}]},{"referenceNumber":2,"citation":{"id":"CI-16FL7VLO633EQ","citationType":"journal article","authors":["Nasmith C.","Jeng R.","Hubbes M."],"citationCrossReferences":[{"database":"DOI","id":"10.1111/j.1439-0329.2007.00523.x"}],"title":"Targeted gene analysis in Ulmus americana and U. pumila tissues.","publicationDate":"2008","journal":"For. Pathol.","firstPage":"90","lastPage":"103","volume":"38"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAY82489.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ078283","properties":[{"key":"ProteinId","value":"AAY82489.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"Q4PJV7","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"FunFam","id":"3.80.10.10:FF:000400","properties":[{"key":"EntryName","value":"Nuclear pore complex protein NUP107"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.80.10.10","properties":[{"key":"EntryName","value":"Ribonuclease Inhibitor"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR001611","properties":[{"key":"EntryName","value":"Leu-rich_rpt"}]},{"database":"InterPro","id":"IPR032675","properties":[{"key":"EntryName","value":"LRR_dom_sf"}]},{"database":"InterPro","id":"IPR051848","properties":[{"key":"EntryName","value":"PGIP"}]},{"database":"PANTHER","id":"PTHR48059","properties":[{"key":"EntryName","value":"POLYGALACTURONASE INHIBITOR 1"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR48059:SF4","properties":[{"key":"EntryName","value":"POLYGALACTURONASE INHIBITOR 1-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00560","properties":[{"key":"EntryName","value":"LRR_1"},{"key":"MatchStatus","value":"4"}]},{"database":"SUPFAM","id":"SSF52058","properties":[{"key":"EntryName","value":"L domain-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"TDCCDWYCVTCDPKTHRINSLTVITGSLTGQIPPQVGDLPFLETLEFHKQANLTGPIQPAIAKLSKLKVLTLSWTNLTGSVPDFISNLKNLTFLDVSFNNLTGSIPSSLSKLENLLSIRLDWNKLTGLIPESFGDFPGNGPDINLAYNQLSGKIPDSLKKKKNFDRIDLSRNRLEGDGSVIFGSNKMTQIVDLSRNLLEFDVSKVEFSKSLILIDLNHNKIFGSLPVGLTALDKLQGFNVSYNRLCGEIPVGGKLQSFNDTSYFHNRCLCGAPLPSCK","length":278,"molWeight":30608,"crc64":"E31B8F9E5236FD4F","md5":"53CBA2D4A489BEAB553A6CE85AE88ED3"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Non-terminal residue":1},"uniParcId":"UPI0000538876"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q6SQ26","uniProtkbId":"Q6SQ26_ULMAM","entryAudit":{"firstPublicDate":"2004-07-05","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"2004-07-05","entryVersion":36,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Ulmus americana","commonName":"American elm","taxonId":29740,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAR20305.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","fabids","Rosales","Ulmaceae","Ulmus"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAR20305.1"}],"value":"Maturase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAR20305.1"}],"value":"matR"}}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAR20305.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":496,"modifier":"EXACT"},"end":{"value":496,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAR20305.1"}]}],"geneLocations":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAR20305.1"}],"geneEncodingType":"Mitochondrion"}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAR20305.1"}],"id":"KW-0496","category":"Cellular component","name":"Mitochondrion"}],"references":[{"referenceNumber":1,"citation":{"id":"14715901","citationType":"journal article","authors":["Barkman T.J.","Lim S.H.","Salleh K.M.","Nais J."],"citationCrossReferences":[{"database":"PubMed","id":"14715901"},{"database":"DOI","id":"10.1073/pnas.0305562101"}],"title":"Mitochondrial DNA sequences reveal the photosynthetic relatives of Rafflesia, the world's largest flower.","publicationDate":"2004","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"787","lastPage":"792","volume":"101"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAR20305.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY453107","properties":[{"key":"ProteinId","value":"AAR20305.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"Q6SQ26","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005739","properties":[{"key":"GoTerm","value":"C:mitochondrion"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0003964","properties":[{"key":"GoTerm","value":"F:RNA-directed DNA polymerase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006315","properties":[{"key":"GoTerm","value":"P:homing of group II introns"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0090615","properties":[{"key":"GoTerm","value":"P:mitochondrial mRNA processing"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"PANTHER","id":"PTHR33642","properties":[{"key":"EntryName","value":"COX1/OXI3 INTRON 1 PROTEIN-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33642:SF5","properties":[{"key":"EntryName","value":"MATURASE"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"LIPIFKEEIDDPKFFYSIQKVFSAGRLVGGEKGPYSVPHSVLLSALPGNIYLHKLDQEIGRIRQKYEIPIVQRIRSVLLRTGRIDDQENSGEEASFNAPQDNRAIIVGRVKSFQRKAAFHSLVSSWHTPPTSTPRLRGDQKTPFVFPPSSALAAFLNKPSSLLCAAFLIEAAGLTPKAEFYGGERCNNKRDLIKYCKRKGLLIELGGEAILVIRSERRLARKLAPLKTHYLIRICYARYADDSLLGIVGAVELLIEIQKRIAHFLQSGLNLLVGSAGSTTIAARSTVEFPGTVIREVPPRTTPIQFLRELEKRLRVKHRIHITACHLRSAIHSKFRNLGNSIPIKQLTKGMSETGSLLDGVQLAETLGTAGVRGPQVSVLWGTVKHIRQGSRGISLLHSSGRSNAPSDVQQAVSRSGMSVRKLSLYTPPGRKAAGEGGGHWAGSISSEFPIQIEAPIKKILRRLRDRGIISRRRPWPIHVACLTNVSDGDIVNWSA","length":496,"molWeight":54754,"crc64":"DBD5AA77B54A1BC0","md5":"3DA4ABB920DB96FF8200E911903A26A5"},"extraAttributes":{"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI0000233885"}}]}