{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A126WV63","uniProtkbId":"A0A126WV63_9ASTR","entryAudit":{"firstPublicDate":"2016-05-11","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2016-05-11","entryVersion":37,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Curio rowleyanus","taxonId":189246,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76505.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","asterids","campanulids","Asterales","Asteraceae","Asteroideae","Senecioneae","Senecioninae","Curio"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"non-specific serine/threonine protein kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"2.7.11.1"}]}},"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047899"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"FMN","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001917"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:58210"}}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004202"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004202"}],"value":"Peripheral membrane protein","id":"SL-9903"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009903"}],"value":"Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":190,"modifier":"EXACT"},"end":{"value":260,"modifier":"EXACT"}},"description":"PAS","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50112"}]},{"type":"Domain","location":{"start":{"value":264,"modifier":"EXACT"},"end":{"value":318,"modifier":"EXACT"}},"description":"PAC","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50113"}]},{"type":"Domain","location":{"start":{"value":500,"modifier":"EXACT"},"end":{"value":569,"modifier":"EXACT"}},"description":"PAS","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50112"}]},{"type":"Domain","location":{"start":{"value":570,"modifier":"EXACT"},"end":{"value":624,"modifier":"EXACT"}},"description":"PAC","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50113"}]},{"type":"Domain","location":{"start":{"value":697,"modifier":"EXACT"},"end":{"value":987,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":27,"modifier":"EXACT"},"end":{"value":67,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":137,"modifier":"EXACT"},"end":{"value":182,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":348,"modifier":"EXACT"},"end":{"value":406,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":444,"modifier":"EXACT"},"end":{"value":491,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":30,"modifier":"EXACT"},"end":{"value":47,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":151,"modifier":"EXACT"},"end":{"value":167,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":359,"modifier":"EXACT"},"end":{"value":376,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":444,"modifier":"EXACT"},"end":{"value":457,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":461,"modifier":"EXACT"},"end":{"value":471,"modifier":"EXACT"}},"description":"Acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":472,"modifier":"EXACT"},"end":{"value":491,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":822,"modifier":"EXACT"},"end":{"value":822,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":726,"modifier":"EXACT"},"end":{"value":726,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022991"}],"id":"KW-0157","category":"Ligand","name":"Chromophore"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022630"}],"id":"KW-0285","category":"Ligand","name":"Flavoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022643"}],"id":"KW-0288","category":"Ligand","name":"FMN"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022543"}],"id":"KW-0600","category":"Molecular function","name":"Photoreceptor protein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023170"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022606"}],"id":"KW-0716","category":"Biological process","name":"Sensory transduction"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"26929367","citationType":"journal article","authors":["Glantz S.T.","Carpenter E.J.","Melkonian M.","Gardner K.H.","Boyden E.S.","Wong G.K.","Chow B.Y."],"citationCrossReferences":[{"database":"PubMed","id":"26929367"},{"database":"DOI","id":"10.1073/pnas.1509428113"}],"title":"Functional and topological diversity of LOV domain photoreceptors.","publicationDate":"2016","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"E1442","lastPage":"E1451","volume":"113"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76505.1"}],"value":"BMSE_2065290","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76505.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KU698338","properties":[{"key":"ProteinId","value":"AML76505.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A126WV63","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0009882","properties":[{"key":"GoTerm","value":"F:blue light photoreceptor activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0010181","properties":[{"key":"GoTerm","value":"F:FMN binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0042802","properties":[{"key":"GoTerm","value":"F:identical protein binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0004674","properties":[{"key":"GoTerm","value":"F:protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0009902","properties":[{"key":"GoTerm","value":"P:chloroplast relocation"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0007623","properties":[{"key":"GoTerm","value":"P:circadian rhythm"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0009638","properties":[{"key":"GoTerm","value":"P:phototropism"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd00130","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"CDD","id":"cd05574","properties":[{"key":"EntryName","value":"STKc_phototropin_like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000133","properties":[{"key":"EntryName","value":"LOV domain-containing protein"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.450.20:FF:000002","properties":[{"key":"EntryName","value":"LOV domain-containing protein"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000265","properties":[{"key":"EntryName","value":"Putative LOV domain-containing protein"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.450.20:FF:000036","properties":[{"key":"EntryName","value":"Putative LOV domain-containing protein"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.450.20","properties":[{"key":"EntryName","value":"PAS domain"},{"key":"MatchStatus","value":"2"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR001610","properties":[{"key":"EntryName","value":"PAC"}]},{"database":"InterPro","id":"IPR000014","properties":[{"key":"EntryName","value":"PAS"}]},{"database":"InterPro","id":"IPR000700","properties":[{"key":"EntryName","value":"PAS-assoc_C"}]},{"database":"InterPro","id":"IPR035965","properties":[{"key":"EntryName","value":"PAS-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"NCBIfam","id":"TIGR00229","properties":[{"key":"EntryName","value":"sensory_box"},{"key":"MatchStatus","value":"2"}]},{"database":"PANTHER","id":"PTHR45637","properties":[{"key":"EntryName","value":"FLIPPASE KINASE 1-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13426","properties":[{"key":"EntryName","value":"PAS_9"},{"key":"MatchStatus","value":"2"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00086","properties":[{"key":"EntryName","value":"PAC"},{"key":"MatchStatus","value":"2"}]},{"database":"SMART","id":"SM00091","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55785","properties":[{"key":"EntryName","value":"PYP-like sensor domain (PAS domain)"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS50113","properties":[{"key":"EntryName","value":"PAC"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS50112","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MESNKHAQNKPSSAFLPAQRDVRGSLEVFNPSSSDDTVQFRSQSTWRNWAESPQNNPEPLPQPQQLTNVNAGLTSSQSGRLPADEIKSWMALKDHMPPQSPPFALSSTAAVVAPRSPGGIVGAAEQRAAEWGLVLQKDTETGKPQGVKVRTSGEDPNAKLETNRRDSGTSVHSSSDVSDDGLGKGGFLRVSEDLKDALSTFQQTFVVSDATKPDYPILYASAGFFKMTGYTSKEVIGRNCRFLQGADTDPEDVAKIREALVKGTTYCGRLLNYKKDGSTFWNLLTVSPIKDESGNILKFIGMQVEVSKHTEGTKEKTLRPNGLPESLIRYDARQKDMATSSVTELVEAVKRPRSLSESTNRHPFEKDSKTNSDLNKDGVLSLGRRKSAETMFAPPPPPPPNRRNSHAGVRTITTMQPIHELPEKKTKKSKRLSFIGIKKKNRKSSEDFDDGFERDINIQDTDGEGDDEDDDYDHKTNDSRPESLDDDKVRKKEMRKGIDLATTLERIEKNFVITDPRLPDNPIIFASDSFLELTEYSREEILGRNCRFLQGPETDPSTVKKIRDAIDNQREVTVQLINYTKSGKKFWNLFHLQPMRDQKGEVQYFIGVQLDGSQHVEPLHNCIPETACKDGAILIKETAENVDVAVRELPDANMTPDDLWAKHSNAVHPKPHRRDTSAWKAILKVIESGEELGLKHFKPIKPLGSGDTGSVHLVELCGTGEFFAMKAMDKGVMINRNKVHRACAERDILDVLDHPFLPALYASFQTPSHVCLITDYCPGGELFMLLDRQPMKVLKEDAVRFYAAEVLVALEYLHCQGIIYRDLKPENVLIQSTGHVALTDFDLSCLTSCKPQLLIPEISEKKKKKKHNKSQQNPIFIAEPVRASNSFVGTEEYIAPEIISGAGHSSAVDWWALGILLYEMFYGYTPFRGKTRQRTFANVLHKDLKFPGSIPVSLEAKQLIYRLLHRDPKNRLGSREGASEVKRHPFFRGINWALVRCQNPPKLETPVFGENEDEEVKEVDPGLTDLENNVF","length":1031,"molWeight":115456,"crc64":"0F44BB9ABCB69476","md5":"2176EB4606032CF4633CC504A724B53D"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":2,"COFACTOR":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":2},"countByFeatureType":{"Domain":5,"Region":4,"Compositional bias":6,"Active site":1,"Binding site":1},"uniParcId":"UPI00078E5579"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A126WV78","uniProtkbId":"A0A126WV78_9ASTR","entryAudit":{"firstPublicDate":"2016-05-11","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2016-05-11","entryVersion":37,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Curio rowleyanus","taxonId":189246,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76503.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","asterids","campanulids","Asterales","Asteraceae","Asteroideae","Senecioneae","Senecioninae","Curio"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"non-specific serine/threonine protein kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"2.7.11.1"}]}},"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047899"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"FMN","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001917"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:58210"}}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004202"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004202"}],"value":"Peripheral membrane protein","id":"SL-9903"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009903"}],"value":"Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":89,"modifier":"EXACT"},"end":{"value":162,"modifier":"EXACT"}},"description":"PAS","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50112"}]},{"type":"Domain","location":{"start":{"value":163,"modifier":"EXACT"},"end":{"value":217,"modifier":"EXACT"}},"description":"PAC","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50113"}]},{"type":"Domain","location":{"start":{"value":353,"modifier":"EXACT"},"end":{"value":426,"modifier":"EXACT"}},"description":"PAS","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50112"}]},{"type":"Domain","location":{"start":{"value":427,"modifier":"EXACT"},"end":{"value":481,"modifier":"EXACT"}},"description":"PAC","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50113"}]},{"type":"Domain","location":{"start":{"value":554,"modifier":"EXACT"},"end":{"value":840,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":33,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":64,"modifier":"EXACT"},"end":{"value":87,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":711,"modifier":"EXACT"},"end":{"value":735,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":10,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":679,"modifier":"EXACT"},"end":{"value":679,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":583,"modifier":"EXACT"},"end":{"value":583,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022991"}],"id":"KW-0157","category":"Ligand","name":"Chromophore"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022630"}],"id":"KW-0285","category":"Ligand","name":"Flavoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022643"}],"id":"KW-0288","category":"Ligand","name":"FMN"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022543"}],"id":"KW-0600","category":"Molecular function","name":"Photoreceptor protein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023170"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022606"}],"id":"KW-0716","category":"Biological process","name":"Sensory transduction"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"26929367","citationType":"journal article","authors":["Glantz S.T.","Carpenter E.J.","Melkonian M.","Gardner K.H.","Boyden E.S.","Wong G.K.","Chow B.Y."],"citationCrossReferences":[{"database":"PubMed","id":"26929367"},{"database":"DOI","id":"10.1073/pnas.1509428113"}],"title":"Functional and topological diversity of LOV domain photoreceptors.","publicationDate":"2016","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"E1442","lastPage":"E1451","volume":"113"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76503.1"}],"value":"BMSE_2013404","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76503.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KU698336","properties":[{"key":"ProteinId","value":"AML76503.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A126WV78","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0009882","properties":[{"key":"GoTerm","value":"F:blue light photoreceptor activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0010181","properties":[{"key":"GoTerm","value":"F:FMN binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0042802","properties":[{"key":"GoTerm","value":"F:identical protein binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0004674","properties":[{"key":"GoTerm","value":"F:protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0009902","properties":[{"key":"GoTerm","value":"P:chloroplast relocation"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0007623","properties":[{"key":"GoTerm","value":"P:circadian rhythm"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0009638","properties":[{"key":"GoTerm","value":"P:phototropism"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd00130","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"CDD","id":"cd05574","properties":[{"key":"EntryName","value":"STKc_phototropin_like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000133","properties":[{"key":"EntryName","value":"LOV domain-containing protein"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.450.20:FF:000002","properties":[{"key":"EntryName","value":"LOV domain-containing protein"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000265","properties":[{"key":"EntryName","value":"Putative LOV domain-containing protein"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.450.20:FF:000036","properties":[{"key":"EntryName","value":"Putative LOV domain-containing protein"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.450.20","properties":[{"key":"EntryName","value":"PAS domain"},{"key":"MatchStatus","value":"2"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR001610","properties":[{"key":"EntryName","value":"PAC"}]},{"database":"InterPro","id":"IPR000014","properties":[{"key":"EntryName","value":"PAS"}]},{"database":"InterPro","id":"IPR000700","properties":[{"key":"EntryName","value":"PAS-assoc_C"}]},{"database":"InterPro","id":"IPR035965","properties":[{"key":"EntryName","value":"PAS-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"NCBIfam","id":"TIGR00229","properties":[{"key":"EntryName","value":"sensory_box"},{"key":"MatchStatus","value":"2"}]},{"database":"PANTHER","id":"PTHR45637","properties":[{"key":"EntryName","value":"FLIPPASE KINASE 1-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13426","properties":[{"key":"EntryName","value":"PAS_9"},{"key":"MatchStatus","value":"2"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00086","properties":[{"key":"EntryName","value":"PAC"},{"key":"MatchStatus","value":"2"}]},{"database":"SMART","id":"SM00091","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55785","properties":[{"key":"EntryName","value":"PYP-like sensor domain (PAS domain)"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS50113","properties":[{"key":"EntryName","value":"PAC"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS50112","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MERSDAESSTDKWMAFAKDSNQNKPPMARVTPPENDEFDIAIIAERTAEWPGVAAVASLIGDNERNKRSSSTSWRSSRDDSLSYHQPRVSQELKEALATLQQTFVVSDATKPDCPIMYASSGFFTMTGYSSKEVIGRNCRFLQGKDTDQNEVDKIRNAVKTGSSYCGRLYNYKKDGTPFWNLLTITPIKDETGKTIKFIGMQVEVSKYTEGANEKELRPNGLPTSLIRYDARQKETALGSIVEVVQTVERPRKTEIQESPLAAGSVETLNLNMPGRETPLFDPKAANLSRTTSWNASNTKSRKSIHSSLMGFKGRSSTHEPQPIVEPEELMTKDIARTDSWDHGVERVRDMRQGIDLATTLERIEKNFVITDPRLPDNPIIFASDSFLELTEFTREEILGRNCRFLQGPETDQGTVDKIRAAIKEQREITVQLINYTKSGKKFWNLFHLQPMRDQKGELQYFIGVQLDGSGHVEPLRNRLSDTTEKQSAKLVKATAENVDEAVRELPDANSRPEDLWAIHSQPVFPRPHKMYNSSWKAIQKITAFGEIVGLDHFKPIRPLGSGDTGSVHLVELKGTGELFAMKAMDKTVMLNRNKVHRACIEREIIALLDHPFLPTLYTSFQTPTHVCLITDFCPGGELFALLDKQPLKLFKEESARFYAAEVVIGLEYLHCLGIIYRDLKPENILLQTDGHVVLSDFDLSFRTQCKPQVIKHPQTKRRRSRSQPPPTFVAEPSTQSNSFVGTEEYIAPEIITGAGHSSAIDWWAVGILLYEMLYGRTPFRGKNRQKTFANILQKDLTFPSSIPVSLAARQLIHALLNRDPATRLGSEGGSNAIKEHSFFRGINWPLIRCMSPPSLDAPLELIEKDPNAQDVQWDDGTMLDNSLDVF","length":887,"molWeight":99894,"crc64":"9224EC48F9D2C8B8","md5":"23AFE5F8FDAE7ACCC128269972B870BA"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":2,"COFACTOR":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":2},"countByFeatureType":{"Domain":5,"Region":3,"Compositional bias":1,"Active site":1,"Binding site":1},"uniParcId":"UPI00078E5E1C"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A126WWB9","uniProtkbId":"A0A126WWB9_9ASTR","entryAudit":{"firstPublicDate":"2016-05-11","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2016-05-11","entryVersion":27,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Curio rowleyanus","taxonId":189246,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76504.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","asterids","campanulids","Asterales","Asteraceae","Asteroideae","Senecioneae","Senecioninae","Curio"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76504.1"}],"value":"Putative LOV domain-containing protein"}}]},"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004906"}],"value":"Protein modification; protein ubiquitination"}],"commentType":"PATHWAY"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004123"}],"value":"Nucleus","id":"SL-0191"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00007833"}],"value":"Belongs to the ADAGIO family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":32,"modifier":"EXACT"},"end":{"value":107,"modifier":"EXACT"}},"description":"PAS","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50112"}]},{"type":"Domain","location":{"start":{"value":209,"modifier":"EXACT"},"end":{"value":242,"modifier":"EXACT"}},"description":"F-box","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50181"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023108"}],"id":"KW-0090","category":"Biological process","name":"Biological rhythms"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022991"}],"id":"KW-0157","category":"Ligand","name":"Chromophore"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022630"}],"id":"KW-0285","category":"Ligand","name":"Flavoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023089"}],"id":"KW-0287","category":"Biological process","name":"Flowering"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022643"}],"id":"KW-0288","category":"Ligand","name":"FMN"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022441"}],"id":"KW-0880","category":"Domain","name":"Kelch repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023242"}],"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022543"}],"id":"KW-0600","category":"Molecular function","name":"Photoreceptor protein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023170"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022606"}],"id":"KW-0716","category":"Biological process","name":"Sensory transduction"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022786"}],"id":"KW-0833","category":"Biological process","name":"Ubl conjugation pathway"}],"references":[{"referenceNumber":1,"citation":{"id":"26929367","citationType":"journal article","authors":["Glantz S.T.","Carpenter E.J.","Melkonian M.","Gardner K.H.","Boyden E.S.","Wong G.K.","Chow B.Y."],"citationCrossReferences":[{"database":"PubMed","id":"26929367"},{"database":"DOI","id":"10.1073/pnas.1509428113"}],"title":"Functional and topological diversity of LOV domain photoreceptors.","publicationDate":"2016","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"E1442","lastPage":"E1451","volume":"113"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76504.1"}],"value":"BMSE_2015280","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76504.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KU698337","properties":[{"key":"ProteinId","value":"AML76504.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A126WWB9","properties":[{"key":"Description","value":"-"}]},{"database":"UniPathway","id":"UPA00143","properties":[{"key":"RectionId","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0019005","properties":[{"key":"GoTerm","value":"C:SCF ubiquitin ligase complex"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0007623","properties":[{"key":"GoTerm","value":"P:circadian rhythm"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0016567","properties":[{"key":"GoTerm","value":"P:protein ubiquitination"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniPathway"}]},{"database":"GO","id":"GO:0009637","properties":[{"key":"GoTerm","value":"P:response to blue light"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006511","properties":[{"key":"GoTerm","value":"P:ubiquitin-dependent protein catabolic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd22154","properties":[{"key":"EntryName","value":"F-box_AtADO-like"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd00130","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.20.1280.50:FF:000021","properties":[{"key":"EntryName","value":"Adagio protein 1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.450.20:FF:000041","properties":[{"key":"EntryName","value":"Adagio protein 1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.120.10.80:FF:000005","properties":[{"key":"EntryName","value":"Putative LOV domain-containing protein"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.120.10.80:FF:000062","properties":[{"key":"EntryName","value":"Putative LOV domain-containing protein"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.1280.50","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.120.10.80","properties":[{"key":"EntryName","value":"Kelch-type beta propeller"},{"key":"MatchStatus","value":"2"}]},{"database":"Gene3D","id":"3.30.450.20","properties":[{"key":"EntryName","value":"PAS domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR036047","properties":[{"key":"EntryName","value":"F-box-like_dom_sf"}]},{"database":"InterPro","id":"IPR001810","properties":[{"key":"EntryName","value":"F-box_dom"}]},{"database":"InterPro","id":"IPR011043","properties":[{"key":"EntryName","value":"Gal_Oxase/kelch_b-propeller"}]},{"database":"InterPro","id":"IPR015915","properties":[{"key":"EntryName","value":"Kelch-typ_b-propeller"}]},{"database":"InterPro","id":"IPR011498","properties":[{"key":"EntryName","value":"Kelch_2"}]},{"database":"InterPro","id":"IPR000014","properties":[{"key":"EntryName","value":"PAS"}]},{"database":"InterPro","id":"IPR035965","properties":[{"key":"EntryName","value":"PAS-like_dom_sf"}]},{"database":"PANTHER","id":"PTHR46175:SF5","properties":[{"key":"EntryName","value":"ADAGIO PROTEIN 1"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR46175","properties":[{"key":"EntryName","value":"BACTERIOOPSIN TRANSCRIPTIONAL ACTIVATOR"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF12937","properties":[{"key":"EntryName","value":"F-box-like"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07646","properties":[{"key":"EntryName","value":"Kelch_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF24681","properties":[{"key":"EntryName","value":"Kelch_KLHDC2_KLHL20_DRC7"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13426","properties":[{"key":"EntryName","value":"PAS_9"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00256","properties":[{"key":"EntryName","value":"FBOX"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF81383","properties":[{"key":"EntryName","value":"F-box domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF50965","properties":[{"key":"EntryName","value":"Galactose oxidase, central domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55785","properties":[{"key":"EntryName","value":"PYP-like sensor domain (PAS domain)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50181","properties":[{"key":"EntryName","value":"FBOX"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50112","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MEWDSSNSDLSGDEDGFLLNDGGPLPFPVDSLLQPAPCGFVVTDALEPDHPIIYVNSVFEIITGYRAEEVLGRNCRFLQCRGPYAKRRHPLVDSTVVSEIRRCIDDGIEFKGELLNFTKDGTPLMNRLRMTPIYGDDEVITHIIGIQFFTEVDLDLGPLPGSTTKGTVKSSDRFRSSLLSCRLTPDGTRNSSRELCGILQLSDEVISLKILSRLTPRDIASVGSVCRRFYEVAKNEDLWRMVCQNAWGSETTRVLETVPGAKRLGWGRLARELTTLEAAAWRKLTVGGGVEPSRCNFSACAVGNRVVLFGGEGVNMQPMNDTFVLDLNSSKPEWQHVKVGSPPPGRWGHTLSCVNGSNLVVFGGCGTQGLLNDVFVLDLDAKHPTWREISGLAPPLPRSWHSSCTLDGTKLIVSGGCADSGVLLSDTFLLDLSMEKPIWREIPVTWTPPSRLGHTLSVYGGRKILMFGGLAKSGPLRFRSSDVFTMDLSEDEPCWRSVTGSGMPGAGNPGGIGPPPRLDHVAVSLPGGRILVFGGSVAGLHSASQLYILDPTEEKPTWRILNVPGRPPRFAWGHSTCVVGGTRAIVLGGQTGEEWMLSELHELSLASSVI","length":610,"molWeight":66305,"crc64":"64F41CFAA7BA9D01","md5":"F4A4D864A9A6DD3BFA91CAD44DC62EF2"},"extraAttributes":{"countByCommentType":{"PATHWAY":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Domain":2},"uniParcId":"UPI00078D8292"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A126WV62","uniProtkbId":"A0A126WV62_9ASTR","entryAudit":{"firstPublicDate":"2016-05-11","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2016-05-11","entryVersion":21,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Curio rowleyanus","taxonId":189246,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76502.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","asterids","campanulids","Asterales","Asteraceae","Asteroideae","Senecioneae","Senecioninae","Curio"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76502.1"}],"value":"Putative LOV domain-containing protein"}}]},"features":[{"type":"Domain","location":{"start":{"value":18,"modifier":"EXACT"},"end":{"value":63,"modifier":"EXACT"}},"description":"PAS","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50112"}]},{"type":"Domain","location":{"start":{"value":246,"modifier":"EXACT"},"end":{"value":268,"modifier":"EXACT"}},"description":"PAS","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50112"}]},{"type":"Region","location":{"start":{"value":158,"modifier":"EXACT"},"end":{"value":179,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022991"}],"id":"KW-0157","category":"Ligand","name":"Chromophore"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022630"}],"id":"KW-0285","category":"Ligand","name":"Flavoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022643"}],"id":"KW-0288","category":"Ligand","name":"FMN"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022543"}],"id":"KW-0600","category":"Molecular function","name":"Photoreceptor protein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023170"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022606"}],"id":"KW-0716","category":"Biological process","name":"Sensory transduction"}],"references":[{"referenceNumber":1,"citation":{"id":"26929367","citationType":"journal article","authors":["Glantz S.T.","Carpenter E.J.","Melkonian M.","Gardner K.H.","Boyden E.S.","Wong G.K.","Chow B.Y."],"citationCrossReferences":[{"database":"PubMed","id":"26929367"},{"database":"DOI","id":"10.1073/pnas.1509428113"}],"title":"Functional and topological diversity of LOV domain photoreceptors.","publicationDate":"2016","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"E1442","lastPage":"E1451","volume":"113"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76502.1"}],"value":"BMSE_2006114","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AML76502.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KU698335","properties":[{"key":"ProteinId","value":"AML76502.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A126WV62","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0009637","properties":[{"key":"GoTerm","value":"P:response to blue light"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd00130","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"Gene3D","id":"3.30.450.20","properties":[{"key":"EntryName","value":"PAS domain"},{"key":"MatchStatus","value":"2"}]},{"database":"InterPro","id":"IPR001610","properties":[{"key":"EntryName","value":"PAC"}]},{"database":"InterPro","id":"IPR000014","properties":[{"key":"EntryName","value":"PAS"}]},{"database":"InterPro","id":"IPR035965","properties":[{"key":"EntryName","value":"PAS-like_dom_sf"}]},{"database":"NCBIfam","id":"TIGR00229","properties":[{"key":"EntryName","value":"sensory_box"},{"key":"MatchStatus","value":"2"}]},{"database":"PANTHER","id":"PTHR47429","properties":[{"key":"EntryName","value":"PROTEIN TWIN LOV 1"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR47429:SF2","properties":[{"key":"EntryName","value":"PROTEIN TWIN LOV 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13426","properties":[{"key":"EntryName","value":"PAS_9"},{"key":"MatchStatus","value":"2"}]},{"database":"SMART","id":"SM00086","properties":[{"key":"EntryName","value":"PAC"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF55785","properties":[{"key":"EntryName","value":"PYP-like sensor domain (PAS domain)"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS50112","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]}],"sequence":{"value":"MGDIGIEESINTRYSFWVREALDELPYSFTITDPSISGHPIVFASRDFLKLCGYSRQEVIGKNGRMFQGIMTNRRSVTEIRHAIIQETTIQITLLNYTKNGTPYWILFHMFPVFDHGRLVHFVGIQIPIIIPPTHVLPLLGFCRREVYDLPFISNLPLPQDDDTPPPRPPRTGDLSHATDLEKRGAKTAMINILSILTHYSQLTGRLVSDKRCHCSTYIPASLNLSLARIKQSFVLTDPHKTDIPIVYASEAFLELTGYTRHEVLGQNCRFLSGQETDVSTQLQITNSIQTRKPCCVCILNYRKDGSPFWNSLQMSAVRNASGKIAYFVEVQMEMEVNPPEKQNLSLKMRQLSVVGAVKVAVRSSASDL","length":369,"molWeight":41686,"crc64":"7D250B401FAC564B","md5":"0C3CB6EEECD832878328CA814F783AED"},"extraAttributes":{"countByFeatureType":{"Domain":2,"Region":1},"uniParcId":"UPI00078D3FF2"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q8MDM8","uniProtkbId":"Q8MDM8_9ASTR","entryAudit":{"firstPublicDate":"2002-10-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2002-10-01","entryVersion":36,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Curio rowleyanus","taxonId":189246,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAM52279.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","asterids","campanulids","Asterales","Asteraceae","Asteroideae","Senecioneae","Senecioninae","Curio"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAM52279.1"}],"value":"Maturase K"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAM52279.1"}],"value":"matK"}}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004474"}],"value":"Plastid","id":"SL-0209"}}]}],"features":[{"type":"Domain","location":{"start":{"value":4,"modifier":"EXACT"},"end":{"value":89,"modifier":"EXACT"}},"description":"Domain X","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF01348"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAM52279.1"}]}],"geneLocations":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAM52279.1"}],"geneEncodingType":"Chloroplast"}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAM52279.1"}],"id":"KW-0150","category":"Cellular component","name":"Chloroplast"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022664"}],"id":"KW-0507","category":"Biological process","name":"mRNA processing"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022640"},{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAM52279.1"}],"id":"KW-0934","category":"Cellular component","name":"Plastid"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022884"}],"id":"KW-0694","category":"Molecular function","name":"RNA-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022694"}],"id":"KW-0819","category":"Biological process","name":"tRNA processing"}],"references":[{"referenceNumber":1,"citation":{"id":"21665692","citationType":"journal article","authors":["Pelser P.B.","Gravendeel B.","van der Meijden R."],"citationCrossReferences":[{"database":"PubMed","id":"21665692"}],"title":"Tackling speciose genera: species composition and phylogenetic position of Senecio sect. Jacobaea (Asteraceae) based onplastid and nrDNA sequences.","publicationDate":"2002","journal":"Am. J. Bot.","firstPage":"929","lastPage":"939","volume":"89"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AAM52279.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AF460002","properties":[{"key":"ProteinId","value":"AAM52279.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"Q8MDM8","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0009507","properties":[{"key":"GoTerm","value":"C:chloroplast"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006397","properties":[{"key":"GoTerm","value":"P:mRNA processing"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"InterPro","id":"IPR024937","properties":[{"key":"EntryName","value":"Domain_X"}]},{"database":"InterPro","id":"IPR002866","properties":[{"key":"EntryName","value":"Maturase_MatK"}]},{"database":"PANTHER","id":"PTHR34811","properties":[{"key":"EntryName","value":"MATURASE K"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR34811:SF1","properties":[{"key":"EntryName","value":"MATURASE K"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01348","properties":[{"key":"EntryName","value":"Intron_maturas2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"ADFSDSDIIERFGRIYRNLSHYHSGSSKKKSLYRVKYILRLSCARTLARKHKSTVRAFLKRLGSELLEEFFTEEEQVFSLTFPRVSSISRRLSRGRIWYLDIICINDLANHE","length":112,"molWeight":13245,"crc64":"0093421199BACAF0","md5":"D26860BEE444648BFF10A447ABD6ABE0"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Domain":1,"Non-terminal residue":1},"uniParcId":"UPI0000093C7E"}}]}