{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A7T5V7U3","uniProtkbId":"A0A7T5V7U3_9LECA","entryAudit":{"firstPublicDate":"2021-06-02","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2021-06-02","entryVersion":15,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Pseudephebe pubescens","taxonId":172637,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62646.1"}],"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Pezizomycotina","Lecanoromycetes","OSLEUM clade","Lecanoromycetidae","Lecanorales","Lecanorineae","Parmeliaceae","Pseudephebe"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62646.1"}],"value":"DNA replication licensing factor MCM7"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62646.1"}],"value":"Mcm7"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"value":"Belongs to the MCM family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Domain","location":{"start":{"value":130,"modifier":"EXACT"},"end":{"value":171,"modifier":"EXACT"}},"description":"MCM C-terminal AAA(+) ATPase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50051"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62646.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":171,"modifier":"EXACT"},"end":{"value":171,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62646.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0131","category":"Biological process","name":"Cell cycle"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0235","category":"Biological process","name":"DNA replication"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0539","category":"Cellular component","name":"Nucleus"}],"references":[{"referenceNumber":1,"citation":{"id":"33242583","citationType":"journal article","authors":["Garrido-Benavent I.","Perez-Ortega S.","de Los Rios A.","Mayrhofer H.","Fernandez-Mendoza F."],"citationCrossReferences":[{"database":"PubMed","id":"33242583"}],"title":"Neogene speciation and Pleistocene expansion of the genus Pseudephebe (Parmeliaceae, lichenized fungi) involving multiple colonizations of Antarctica.","publicationDate":"2020","journal":"Mol. Phylogenet. Evol.","firstPage":"0","lastPage":"0","volume":"107020"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62646.1"}],"value":"I803_hap8","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62646.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MT383757","properties":[{"key":"ProteinId","value":"QQG62646.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A0A7T5V7U3","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0031261","properties":[{"key":"GoTerm","value":"C:DNA replication preinitiation complex"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0042555","properties":[{"key":"GoTerm","value":"C:MCM complex"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0005656","properties":[{"key":"GoTerm","value":"C:nuclear pre-replicative complex"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0043596","properties":[{"key":"GoTerm","value":"C:nuclear replication fork"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0003697","properties":[{"key":"GoTerm","value":"F:single-stranded DNA binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0017116","properties":[{"key":"GoTerm","value":"F:single-stranded DNA helicase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006270","properties":[{"key":"GoTerm","value":"P:DNA replication initiation"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006271","properties":[{"key":"GoTerm","value":"P:DNA strand elongation involved in DNA replication"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0000727","properties":[{"key":"GoTerm","value":"P:double-strand break repair via break-induced replication"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006279","properties":[{"key":"GoTerm","value":"P:premeiotic DNA replication"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"Gene3D","id":"2.40.50.140","properties":[{"key":"EntryName","value":"Nucleic acid-binding proteins"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.300","properties":[{"key":"EntryName","value":"P-loop containing nucleotide triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR031327","properties":[{"key":"EntryName","value":"MCM"}]},{"database":"InterPro","id":"IPR001208","properties":[{"key":"EntryName","value":"MCM_dom"}]},{"database":"InterPro","id":"IPR033762","properties":[{"key":"EntryName","value":"MCM_OB"}]},{"database":"InterPro","id":"IPR012340","properties":[{"key":"EntryName","value":"NA-bd_OB-fold"}]},{"database":"InterPro","id":"IPR027417","properties":[{"key":"EntryName","value":"P-loop_NTPase"}]},{"database":"PANTHER","id":"PTHR11630","properties":[{"key":"EntryName","value":"DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11630:SF26","properties":[{"key":"EntryName","value":"DNA REPLICATION LICENSING FACTOR MCM7"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00493","properties":[{"key":"EntryName","value":"MCM"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF17207","properties":[{"key":"EntryName","value":"MCM_OB"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00350","properties":[{"key":"EntryName","value":"MCM"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF50249","properties":[{"key":"EntryName","value":"Nucleic acid-binding proteins"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50051","properties":[{"key":"EntryName","value":"MCM_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MTECPSDECKQNNSKGQLFLSTRASKFLPFQEVKIQEMADQVPVGHIPRTLTVHCHGTLTRQINPGDVIDVAGIFLPTPYTGFKAIRAGLLTDTYLEAQHVNQHKKAYDDLVFDAKTFRRIEQYKHSGHMYEYLSRSIAPEIYGHQDVKKALLLLLIGGVTKEMGDGMRIR","length":171,"molWeight":19346,"crc64":"D0031A596F878F23","md5":"FD176C7C5A89A0FD6AD0E9FA519AB62F"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1,"CAUTION":1},"countByFeatureType":{"Domain":1,"Non-terminal residue":2},"uniParcId":"UPI0019377FC7"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A7T5V857","uniProtkbId":"A0A7T5V857_9LECA","entryAudit":{"firstPublicDate":"2021-06-02","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2021-06-02","entryVersion":18,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Pseudephebe pubescens","taxonId":172637,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62803.1"}],"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Pezizomycotina","Lecanoromycetes","OSLEUM clade","Lecanoromycetidae","Lecanorales","Lecanorineae","Parmeliaceae","Pseudephebe"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00013061"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"value":"Phosphoglycerate kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00013061"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"value":"2.7.2.3"}]},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62803.1"}],"value":"PGK"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:14801"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:57604"},{"database":"ChEBI","id":"CHEBI:58272"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.2.3","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00000642"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"Mg(2+)","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001946"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:18420"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004838"}],"value":"Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000696"}],"value":"Monomer"}],"commentType":"SUBUNIT"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00008982"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"value":"Belongs to the phosphoglycerate kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62803.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":256,"modifier":"EXACT"},"end":{"value":256,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62803.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023152"}],"id":"KW-0324","category":"Biological process","name":"Glycolysis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022842"}],"id":"KW-0460","category":"Ligand","name":"Magnesium"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"33242583","citationType":"journal article","authors":["Garrido-Benavent I.","Perez-Ortega S.","de Los Rios A.","Mayrhofer H.","Fernandez-Mendoza F."],"citationCrossReferences":[{"database":"PubMed","id":"33242583"}],"title":"Neogene speciation and Pleistocene expansion of the genus Pseudephebe (Parmeliaceae, lichenized fungi) involving multiple colonizations of Antarctica.","publicationDate":"2020","journal":"Mol. Phylogenet. Evol.","firstPage":"0","lastPage":"0","volume":"107020"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62803.1"}],"value":"I803_hap10","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62803.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MT383914","properties":[{"key":"ProteinId","value":"QQG62803.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A0A7T5V857","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0043531","properties":[{"key":"GoTerm","value":"F:ADP binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0004618","properties":[{"key":"GoTerm","value":"F:phosphoglycerate kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0006094","properties":[{"key":"GoTerm","value":"P:gluconeogenesis"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006096","properties":[{"key":"GoTerm","value":"P:glycolytic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"FunFam","id":"3.40.50.1260:FF:000031","properties":[{"key":"EntryName","value":"Phosphoglycerate kinase 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.1260","properties":[{"key":"EntryName","value":"Phosphoglycerate kinase, N-terminal domain"},{"key":"MatchStatus","value":"2"}]},{"database":"InterPro","id":"IPR001576","properties":[{"key":"EntryName","value":"Phosphoglycerate_kinase"}]},{"database":"InterPro","id":"IPR015824","properties":[{"key":"EntryName","value":"Phosphoglycerate_kinase_N"}]},{"database":"InterPro","id":"IPR036043","properties":[{"key":"EntryName","value":"Phosphoglycerate_kinase_sf"}]},{"database":"PANTHER","id":"PTHR11406","properties":[{"key":"EntryName","value":"PHOSPHOGLYCERATE KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11406:SF0","properties":[{"key":"EntryName","value":"PHOSPHOGLYCERATE KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00162","properties":[{"key":"EntryName","value":"PGK"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00477","properties":[{"key":"EntryName","value":"PHGLYCKINASE"}]},{"database":"SUPFAM","id":"SSF53748","properties":[{"key":"EntryName","value":"Phosphoglycerate kinase"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"SHLGRPDGHPNPKYSLKPVVPELEKLLGTKVIFTEDCVGKEVEDTVDKASDGQVVLLENLRFHAEEEGSSKDSEGKKVKADKAEVEKFRKGLTALGDVYINDAFGTAHRGHSSMIGVNLPQKASGFLMKKELDYFAQALEKPKRPFLAILGGAKVSDKIQLIDNLLSKVDSLIICGGMAFTFKKTLENVKIGNSLFDEAGSKTVGDLMKKANRNGVKMVLPCDYVTADKFDKDAKIGYATDSEGIPDGWMGLDCGE","length":256,"molWeight":27839,"crc64":"F28C7A494AF2310E","md5":"6F105F62A6B810905BA9AC72BF39B6BA"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"COFACTOR":1,"PATHWAY":1,"SUBUNIT":1,"SIMILARITY":1},"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI001936FDF0"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A7T6AMU6","uniProtkbId":"A0A7T6AMU6_9LECA","entryAudit":{"firstPublicDate":"2021-06-02","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2021-06-02","entryVersion":15,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Pseudephebe pubescens","taxonId":172637,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62655.1"}],"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Pezizomycotina","Lecanoromycetes","OSLEUM clade","Lecanoromycetidae","Lecanorales","Lecanorineae","Parmeliaceae","Pseudephebe"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62655.1"}],"value":"DNA replication licensing factor MCM7"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62655.1"}],"value":"Mcm7"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"value":"Belongs to the MCM family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Domain","location":{"start":{"value":130,"modifier":"EXACT"},"end":{"value":171,"modifier":"EXACT"}},"description":"MCM C-terminal AAA(+) ATPase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50051"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62655.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":171,"modifier":"EXACT"},"end":{"value":171,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62655.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0131","category":"Biological process","name":"Cell cycle"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0235","category":"Biological process","name":"DNA replication"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01410"}],"id":"KW-0539","category":"Cellular component","name":"Nucleus"}],"references":[{"referenceNumber":1,"citation":{"id":"33242583","citationType":"journal article","authors":["Garrido-Benavent I.","Perez-Ortega S.","de Los Rios A.","Mayrhofer H.","Fernandez-Mendoza F."],"citationCrossReferences":[{"database":"PubMed","id":"33242583"}],"title":"Neogene speciation and Pleistocene expansion of the genus Pseudephebe (Parmeliaceae, lichenized fungi) involving multiple colonizations of Antarctica.","publicationDate":"2020","journal":"Mol. Phylogenet. Evol.","firstPage":"0","lastPage":"0","volume":"107020"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62655.1"}],"value":"I656_hap17","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62655.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MT383766","properties":[{"key":"ProteinId","value":"QQG62655.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A0A7T6AMU6","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0031261","properties":[{"key":"GoTerm","value":"C:DNA replication preinitiation complex"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0042555","properties":[{"key":"GoTerm","value":"C:MCM complex"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0005656","properties":[{"key":"GoTerm","value":"C:nuclear pre-replicative complex"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0043596","properties":[{"key":"GoTerm","value":"C:nuclear replication fork"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0003697","properties":[{"key":"GoTerm","value":"F:single-stranded DNA binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0017116","properties":[{"key":"GoTerm","value":"F:single-stranded DNA helicase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006270","properties":[{"key":"GoTerm","value":"P:DNA replication initiation"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006271","properties":[{"key":"GoTerm","value":"P:DNA strand elongation involved in DNA replication"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0000727","properties":[{"key":"GoTerm","value":"P:double-strand break repair via break-induced replication"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006279","properties":[{"key":"GoTerm","value":"P:premeiotic DNA replication"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"Gene3D","id":"2.40.50.140","properties":[{"key":"EntryName","value":"Nucleic acid-binding proteins"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.300","properties":[{"key":"EntryName","value":"P-loop containing nucleotide triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR031327","properties":[{"key":"EntryName","value":"MCM"}]},{"database":"InterPro","id":"IPR001208","properties":[{"key":"EntryName","value":"MCM_dom"}]},{"database":"InterPro","id":"IPR033762","properties":[{"key":"EntryName","value":"MCM_OB"}]},{"database":"InterPro","id":"IPR012340","properties":[{"key":"EntryName","value":"NA-bd_OB-fold"}]},{"database":"InterPro","id":"IPR027417","properties":[{"key":"EntryName","value":"P-loop_NTPase"}]},{"database":"PANTHER","id":"PTHR11630","properties":[{"key":"EntryName","value":"DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11630:SF26","properties":[{"key":"EntryName","value":"DNA REPLICATION LICENSING FACTOR MCM7"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00493","properties":[{"key":"EntryName","value":"MCM"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF17207","properties":[{"key":"EntryName","value":"MCM_OB"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00350","properties":[{"key":"EntryName","value":"MCM"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF50249","properties":[{"key":"EntryName","value":"Nucleic acid-binding proteins"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50051","properties":[{"key":"EntryName","value":"MCM_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MTECPSDECKQNNSKGQLFLSTRASKFLPFQEVKIQEMADQVPVGHIPRTLTVHCHGTLTRQINPGDVIDVAGIFLPTPYTGFKAIRAGLLTDTYLEAQHVNQHKKAYDDLVFHAKTFRRIEQYKHSGHMYEYLSRSIAPEIYGHQDVKKALLLLLIGGVTKEMGDGMRIR","length":171,"molWeight":19368,"crc64":"D00F1659638B8F23","md5":"80DD1ADDBF0F067CF1CD48BAAFBCF7AD"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1,"CAUTION":1},"countByFeatureType":{"Domain":1,"Non-terminal residue":2},"uniParcId":"UPI001936D822"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A7T6AMY6","uniProtkbId":"A0A7T6AMY6_9LECA","entryAudit":{"firstPublicDate":"2021-06-02","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2021-06-02","entryVersion":12,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Pseudephebe pubescens","taxonId":172637,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62688.1"}],"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Pezizomycotina","Lecanoromycetes","OSLEUM clade","Lecanoromycetidae","Lecanorales","Lecanorineae","Parmeliaceae","Pseudephebe"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10009"}],"value":"Glyceraldehyde-3-phosphate dehydrogenase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10009"}],"value":"1.2.1.12"}]},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10009"}],"value":"phosphorylating"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62688.1"}],"value":"GAPDH"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:10300"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:43474"},{"database":"ChEBI","id":"CHEBI:57540"},{"database":"ChEBI","id":"CHEBI:57604"},{"database":"ChEBI","id":"CHEBI:57945"},{"database":"ChEBI","id":"CHEBI:59776"}],"ecNumber":"1.2.1.12","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10009"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004869"}],"value":"Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00011881"}],"value":"Homotetramer"}],"commentType":"SUBUNIT"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00007406"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000397"}],"value":"Belongs to the glyceraldehyde-3-phosphate dehydrogenase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":109,"modifier":"EXACT"}},"description":"Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding","evidences":[{"evidenceCode":"ECO:0000259","source":"SMART","id":"SM00846"}]},{"type":"Active site","location":{"start":{"value":109,"modifier":"EXACT"},"end":{"value":109,"modifier":"EXACT"}},"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10009"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62688.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":232,"modifier":"EXACT"},"end":{"value":232,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62688.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023152"}],"id":"KW-0324","category":"Biological process","name":"Glycolysis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023027"}],"id":"KW-0520","category":"Ligand","name":"NAD"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"}],"references":[{"referenceNumber":1,"citation":{"id":"33242583","citationType":"journal article","authors":["Garrido-Benavent I.","Perez-Ortega S.","de Los Rios A.","Mayrhofer H.","Fernandez-Mendoza F."],"citationCrossReferences":[{"database":"PubMed","id":"33242583"}],"title":"Neogene speciation and Pleistocene expansion of the genus Pseudephebe (Parmeliaceae, lichenized fungi) involving multiple colonizations of Antarctica.","publicationDate":"2020","journal":"Mol. Phylogenet. Evol.","firstPage":"0","lastPage":"0","volume":"107020"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62688.1"}],"value":"I803_hap7","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62688.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MT383799","properties":[{"key":"ProteinId","value":"QQG62688.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A0A7T6AMY6","properties":[{"key":"Description","value":"-"}]},{"database":"UniPathway","id":"UPA00109","properties":[{"key":"RectionId","value":"UER00184"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0004365","properties":[{"key":"GoTerm","value":"F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0051287","properties":[{"key":"GoTerm","value":"F:NAD binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006096","properties":[{"key":"GoTerm","value":"P:glycolytic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniPathway"}]},{"database":"CDD","id":"cd18126","properties":[{"key":"EntryName","value":"GAPDH_I_C"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd05214","properties":[{"key":"EntryName","value":"GAPDH_I_N"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.360.10:FF:000001","properties":[{"key":"EntryName","value":"Glyceraldehyde-3-phosphate dehydrogenase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.40.50.720:FF:000266","properties":[{"key":"EntryName","value":"Glyceraldehyde-3-phosphate dehydrogenase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.360.10","properties":[{"key":"EntryName","value":"Dihydrodipicolinate Reductase, domain 2"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.720","properties":[{"key":"EntryName","value":"NAD(P)-binding Rossmann-like Domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR020831","properties":[{"key":"EntryName","value":"GlycerAld/Erythrose_P_DH"}]},{"database":"InterPro","id":"IPR020830","properties":[{"key":"EntryName","value":"GlycerAld_3-P_DH_AS"}]},{"database":"InterPro","id":"IPR020829","properties":[{"key":"EntryName","value":"GlycerAld_3-P_DH_cat"}]},{"database":"InterPro","id":"IPR020828","properties":[{"key":"EntryName","value":"GlycerAld_3-P_DH_NAD(P)-bd"}]},{"database":"InterPro","id":"IPR036291","properties":[{"key":"EntryName","value":"NAD(P)-bd_dom_sf"}]},{"database":"PANTHER","id":"PTHR10836","properties":[{"key":"EntryName","value":"GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10836:SF76","properties":[{"key":"EntryName","value":"GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02800","properties":[{"key":"EntryName","value":"Gp_dh_C"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00044","properties":[{"key":"EntryName","value":"Gp_dh_N"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00078","properties":[{"key":"EntryName","value":"G3PDHDRGNASE"}]},{"database":"SMART","id":"SM00846","properties":[{"key":"EntryName","value":"Gp_dh_N"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55347","properties":[{"key":"EntryName","value":"Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF51735","properties":[{"key":"EntryName","value":"NAD(P)-binding Rossmann-fold domains"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00071","properties":[{"key":"EntryName","value":"GAPDH"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"AYMLKYDSQHGQFKGTIEVKGSDLVVNGQTVKFYTEKDPANIPWKDTGAYYIIESTGVFTTTEKAKAHLKGGAKKVVISAPSADAAMFVMGVNEKEYKSDIEIISNASCTTNCLAPLAKVMHDNFTIIEGLMTTIHSYTATQKTVDGPSSKDWRGGRTAAQNIIPSSTGAAKAVGKVIPSLNGKLTGMSMRVPTSNVSVVDLTCRLEKSVTYDQIKETMKKASEGELKGIMA","length":232,"molWeight":24956,"crc64":"B35281A2FEC35397","md5":"15DE18267E5EB56A2A688F41EF9FFB68"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"PATHWAY":1,"SUBUNIT":1,"SIMILARITY":1},"countByFeatureType":{"Domain":1,"Active site":1,"Non-terminal residue":2},"uniParcId":"UPI0019363FFF"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A7T6AN25","uniProtkbId":"A0A7T6AN25_9LECA","entryAudit":{"firstPublicDate":"2021-06-02","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2021-06-02","entryVersion":18,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Pseudephebe pubescens","taxonId":172637,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62808.1"}],"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Pezizomycotina","Lecanoromycetes","OSLEUM clade","Lecanoromycetidae","Lecanorales","Lecanorineae","Parmeliaceae","Pseudephebe"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00013061"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"value":"Phosphoglycerate kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00013061"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"value":"2.7.2.3"}]},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62808.1"}],"value":"PGK"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:14801"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:57604"},{"database":"ChEBI","id":"CHEBI:58272"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.2.3","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00000642"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"Mg(2+)","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001946"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:18420"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004838"}],"value":"Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000696"}],"value":"Monomer"}],"commentType":"SUBUNIT"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00008982"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"value":"Belongs to the phosphoglycerate kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62808.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":256,"modifier":"EXACT"},"end":{"value":256,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62808.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023152"}],"id":"KW-0324","category":"Biological process","name":"Glycolysis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022842"}],"id":"KW-0460","category":"Ligand","name":"Magnesium"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"33242583","citationType":"journal article","authors":["Garrido-Benavent I.","Perez-Ortega S.","de Los Rios A.","Mayrhofer H.","Fernandez-Mendoza F."],"citationCrossReferences":[{"database":"PubMed","id":"33242583"}],"title":"Neogene speciation and Pleistocene expansion of the genus Pseudephebe (Parmeliaceae, lichenized fungi) involving multiple colonizations of Antarctica.","publicationDate":"2020","journal":"Mol. Phylogenet. Evol.","firstPage":"0","lastPage":"0","volume":"107020"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62808.1"}],"value":"I567_hap15","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62808.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MT383919","properties":[{"key":"ProteinId","value":"QQG62808.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A0A7T6AN25","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0043531","properties":[{"key":"GoTerm","value":"F:ADP binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0004618","properties":[{"key":"GoTerm","value":"F:phosphoglycerate kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0006094","properties":[{"key":"GoTerm","value":"P:gluconeogenesis"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006096","properties":[{"key":"GoTerm","value":"P:glycolytic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"FunFam","id":"3.40.50.1260:FF:000031","properties":[{"key":"EntryName","value":"Phosphoglycerate kinase 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.1260","properties":[{"key":"EntryName","value":"Phosphoglycerate kinase, N-terminal domain"},{"key":"MatchStatus","value":"2"}]},{"database":"InterPro","id":"IPR001576","properties":[{"key":"EntryName","value":"Phosphoglycerate_kinase"}]},{"database":"InterPro","id":"IPR015824","properties":[{"key":"EntryName","value":"Phosphoglycerate_kinase_N"}]},{"database":"InterPro","id":"IPR036043","properties":[{"key":"EntryName","value":"Phosphoglycerate_kinase_sf"}]},{"database":"PANTHER","id":"PTHR11406","properties":[{"key":"EntryName","value":"PHOSPHOGLYCERATE KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11406:SF0","properties":[{"key":"EntryName","value":"PHOSPHOGLYCERATE KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00162","properties":[{"key":"EntryName","value":"PGK"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00477","properties":[{"key":"EntryName","value":"PHGLYCKINASE"}]},{"database":"SUPFAM","id":"SSF53748","properties":[{"key":"EntryName","value":"Phosphoglycerate kinase"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"SHLGRPDGHPNPKYSLKPVVPELEKLLGTKVIFTEDCVGKEVEDTVDKASDGQVVLLENLRFHAEEEGSSKDSEGKKVKADKAEVEKFRKGLTALGDVYINDAFGTAHRGHSSMIGVNLPQKASGFLMKKELDYFAQALEKPKRPFLAILGGAKVSDKIQLIDNLLSKVDSLIICGGMAFTFKKTLENVKIGNSLFDEAGSKIVGDLMKKANRNGVKMVLPCDYVTADKFDKDAKIGYATDSEGIPDGWMGLDCGE","length":256,"molWeight":27851,"crc64":"BF917A494AE6B7D5","md5":"0F6535C0A5C6CC4030D0E91182F36F76"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"COFACTOR":1,"PATHWAY":1,"SUBUNIT":1,"SIMILARITY":1},"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI0019362391"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A7T6AN38","uniProtkbId":"A0A7T6AN38_9LECA","entryAudit":{"firstPublicDate":"2021-06-02","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2021-06-02","entryVersion":18,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Pseudephebe pubescens","taxonId":172637,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62810.1"}],"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Pezizomycotina","Lecanoromycetes","OSLEUM clade","Lecanoromycetidae","Lecanorales","Lecanorineae","Parmeliaceae","Pseudephebe"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00013061"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"value":"Phosphoglycerate kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00013061"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"value":"2.7.2.3"}]},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62810.1"}],"value":"PGK"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:14801"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:57604"},{"database":"ChEBI","id":"CHEBI:58272"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.2.3","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00000642"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"Mg(2+)","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001946"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:18420"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004838"}],"value":"Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000696"}],"value":"Monomer"}],"commentType":"SUBUNIT"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00008982"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"value":"Belongs to the phosphoglycerate kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62810.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":256,"modifier":"EXACT"},"end":{"value":256,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62810.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023152"}],"id":"KW-0324","category":"Biological process","name":"Glycolysis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022842"}],"id":"KW-0460","category":"Ligand","name":"Magnesium"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000532"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"33242583","citationType":"journal article","authors":["Garrido-Benavent I.","Perez-Ortega S.","de Los Rios A.","Mayrhofer H.","Fernandez-Mendoza F."],"citationCrossReferences":[{"database":"PubMed","id":"33242583"}],"title":"Neogene speciation and Pleistocene expansion of the genus Pseudephebe (Parmeliaceae, lichenized fungi) involving multiple colonizations of Antarctica.","publicationDate":"2020","journal":"Mol. Phylogenet. Evol.","firstPage":"0","lastPage":"0","volume":"107020"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62810.1"}],"value":"I827_hap17","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62810.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MT383921","properties":[{"key":"ProteinId","value":"QQG62810.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A0A7T6AN38","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0043531","properties":[{"key":"GoTerm","value":"F:ADP binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0004618","properties":[{"key":"GoTerm","value":"F:phosphoglycerate kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0006094","properties":[{"key":"GoTerm","value":"P:gluconeogenesis"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006096","properties":[{"key":"GoTerm","value":"P:glycolytic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"FunFam","id":"3.40.50.1260:FF:000031","properties":[{"key":"EntryName","value":"Phosphoglycerate kinase 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.1260","properties":[{"key":"EntryName","value":"Phosphoglycerate kinase, N-terminal domain"},{"key":"MatchStatus","value":"2"}]},{"database":"InterPro","id":"IPR001576","properties":[{"key":"EntryName","value":"Phosphoglycerate_kinase"}]},{"database":"InterPro","id":"IPR015824","properties":[{"key":"EntryName","value":"Phosphoglycerate_kinase_N"}]},{"database":"InterPro","id":"IPR036043","properties":[{"key":"EntryName","value":"Phosphoglycerate_kinase_sf"}]},{"database":"PANTHER","id":"PTHR11406","properties":[{"key":"EntryName","value":"PHOSPHOGLYCERATE KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11406:SF0","properties":[{"key":"EntryName","value":"PHOSPHOGLYCERATE KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00162","properties":[{"key":"EntryName","value":"PGK"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00477","properties":[{"key":"EntryName","value":"PHGLYCKINASE"}]},{"database":"SUPFAM","id":"SSF53748","properties":[{"key":"EntryName","value":"Phosphoglycerate kinase"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"SHLGRPDGHPNPKYSLKPVVPELEKLLGTKVIFTEDCVGKEVEETVDKASGGQVVLLENLRFHAEEEGSSKDSEGKKVKADKAEVEKFRKGLTALGDVYVNDAFGTAHRGHSSMIGVNLPQKASGFLMKKELDYFAQALEKPKRPFLAILGGAKVSDKIQLIDNLLSKVDSLIICGGMAFTFKKTLENVKIGNSLFDEAGSKTVGDLMKKANRNGVKMVLPCDYVTADKFDKDAKIGYATDSEGIPDGWMGLDCGE","length":256,"molWeight":27781,"crc64":"D79EAE9FFE9C708B","md5":"24B4123A840929E2CB89EA733F2B3FBB"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"COFACTOR":1,"PATHWAY":1,"SUBUNIT":1,"SIMILARITY":1},"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI001935B705"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A7K7U8","uniProtkbId":"A7K7U8_9LECA","entryAudit":{"firstPublicDate":"2007-09-11","lastAnnotationUpdateDate":"2025-10-08","lastSequenceUpdateDate":"2007-09-11","entryVersion":44,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Pseudephebe pubescens","taxonId":172637,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABO65359.1"}],"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Pezizomycotina","Lecanoromycetes","OSLEUM clade","Lecanoromycetidae","Lecanorales","Lecanorineae","Parmeliaceae","Pseudephebe"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012418"}],"value":"DNA-directed RNA polymerase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012418"}],"value":"2.7.7.6"}]},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABO65359.1"}],"value":"RPB1"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006460"}],"value":"Belongs to the RNA polymerase beta' chain family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":220,"modifier":"EXACT"}},"description":"RNA polymerase Rpb1","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF04997"}]},{"type":"Region","location":{"start":{"value":62,"modifier":"EXACT"},"end":{"value":83,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":65,"modifier":"EXACT"},"end":{"value":77,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABO65359.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":220,"modifier":"EXACT"},"end":{"value":220,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABO65359.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022478"}],"id":"KW-0240","category":"Cellular component","name":"DNA-directed RNA polymerase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022695"}],"id":"KW-0548","category":"Molecular function","name":"Nucleotidyltransferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023163"}],"id":"KW-0804","category":"Biological process","name":"Transcription"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"17276700","citationType":"journal article","authors":["Crespo A.","Lumbsch H.T.","Mattsson J.E.","Blanco O.","Divakar P.K.","Articus K.","Wiklund E.","Bawingan P.A.","Wedin M."],"citationCrossReferences":[{"database":"PubMed","id":"17276700"},{"database":"DOI","id":"10.1016/j.ympev.2006.11.029"}],"title":"Testing morphology-based hypotheses of phylogenetic relationships in Parmeliaceae (Ascomycota) using three ribosomal markers and the nuclear RPB1 gene.","publicationDate":"2007","journal":"Mol. Phylogenet. Evol.","firstPage":"812","lastPage":"824","volume":"44"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABO65359.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"EF092148","properties":[{"key":"ProteinId","value":"ABO65359.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A7K7U8","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005665","properties":[{"key":"GoTerm","value":"C:RNA polymerase II, core complex"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0003677","properties":[{"key":"GoTerm","value":"F:DNA binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0003899","properties":[{"key":"GoTerm","value":"F:DNA-directed RNA polymerase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0006351","properties":[{"key":"GoTerm","value":"P:DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"4.10.860.120","properties":[{"key":"EntryName","value":"RNA polymerase II, clamp domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR045867","properties":[{"key":"EntryName","value":"DNA-dir_RpoC_beta_prime"}]},{"database":"InterPro","id":"IPR007080","properties":[{"key":"EntryName","value":"RNA_pol_Rpb1_1"}]},{"database":"InterPro","id":"IPR044893","properties":[{"key":"EntryName","value":"RNA_pol_Rpb1_clamp_domain"}]},{"database":"PANTHER","id":"PTHR19376","properties":[{"key":"EntryName","value":"DNA-DIRECTED RNA POLYMERASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR19376:SF37","properties":[{"key":"EntryName","value":"DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF04997","properties":[{"key":"EntryName","value":"RNA_pol_Rpb1_1"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF64484","properties":[{"key":"EntryName","value":"beta and beta-prime subunits of DNA dependent RNA-polymerase"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"FMTKIKKLLETVCHNCGKILVDESHPAFADAIRRRDPKKRFDLVWRLCKPKMICETTMALDDDAPSEKAKEPKHDHGGCGNIQPEVRREGLRLTGTWKAQKGDEENEGQQPEKKPITPQMALNIFRHISTEDIKRMGLSNDYARPEWMIITVLPVPPPPVRPSISVDGGNGPRGEDDLTYKLGDIIRANGNVRRCETEGSPAHVVNEFEQLLQFHVATYM","length":220,"molWeight":24907,"crc64":"378FF0F423C39F25","md5":"6FA75EA83B5D1659DB8C7C5DFF871646"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Domain":1,"Region":1,"Compositional bias":1,"Non-terminal residue":2},"uniParcId":"UPI000159C68D"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A7T5V816","uniProtkbId":"A0A7T5V816_9LECA","entryAudit":{"firstPublicDate":"2021-06-02","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2021-06-02","entryVersion":13,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Pseudephebe pubescens","taxonId":172637,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62729.1"}],"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Pezizomycotina","Lecanoromycetes","OSLEUM clade","Lecanoromycetidae","Lecanorales","Lecanorineae","Parmeliaceae","Pseudephebe"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62729.1"}],"value":"Translation elongation factor 1 alpha"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62729.1"}],"value":"TEF1"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01059"}],"value":"Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01059"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":129,"modifier":"EXACT"}},"description":"Tr-type G","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51722"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62729.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":181,"modifier":"EXACT"},"end":{"value":181,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62729.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62729.1"}],"id":"KW-0251","category":"Molecular function","name":"Elongation factor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023134"}],"id":"KW-0342","category":"Ligand","name":"GTP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62729.1"}],"id":"KW-0648","category":"Biological process","name":"Protein biosynthesis"}],"references":[{"referenceNumber":1,"citation":{"id":"33242583","citationType":"journal article","authors":["Garrido-Benavent I.","Perez-Ortega S.","de Los Rios A.","Mayrhofer H.","Fernandez-Mendoza F."],"citationCrossReferences":[{"database":"PubMed","id":"33242583"}],"title":"Neogene speciation and Pleistocene expansion of the genus Pseudephebe (Parmeliaceae, lichenized fungi) involving multiple colonizations of Antarctica.","publicationDate":"2020","journal":"Mol. Phylogenet. Evol.","firstPage":"0","lastPage":"0","volume":"107020"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62738.1"}],"value":"I571_hap22","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62729.1"}],"value":"I803_hap13","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62729.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MT383840","properties":[{"key":"ProteinId","value":"QQG62729.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"MT383849","properties":[{"key":"ProteinId","value":"QQG62738.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A0A7T5V816","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005525","properties":[{"key":"GoTerm","value":"F:GTP binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0003924","properties":[{"key":"GoTerm","value":"F:GTPase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.40.50.300","properties":[{"key":"EntryName","value":"P-loop containing nucleotide triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.40.30.10","properties":[{"key":"EntryName","value":"Translation factors"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR027417","properties":[{"key":"EntryName","value":"P-loop_NTPase"}]},{"database":"InterPro","id":"IPR000795","properties":[{"key":"EntryName","value":"T_Tr_GTP-bd_dom"}]},{"database":"InterPro","id":"IPR050100","properties":[{"key":"EntryName","value":"TRAFAC_GTPase_members"}]},{"database":"PANTHER","id":"PTHR23115","properties":[{"key":"EntryName","value":"TRANSLATION FACTOR"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00009","properties":[{"key":"EntryName","value":"GTP_EFTU"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52540","properties":[{"key":"EntryName","value":"P-loop containing nucleoside triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51722","properties":[{"key":"EntryName","value":"G_TR_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"CAILIIAAGTGEFEAGISKDGQTREHALLAYTLGVKQLIVAINKMDTAKWSGDRYNEIIKETSNFIKKVGYNPKTVPFVPISGFNGDNMIDESPNCPWYKGWEKETKTKTTGKTLLEAIDAIDPPARPTDKPLRLPLQDVYKIGGIGTVPVGRVETGIIKAGMIVTFAPANVTTEVKSVEM","length":181,"molWeight":19668,"crc64":"EBCF9625D3DF6DA6","md5":"187410F7825E44A5A2EDA5A22B773A6A"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1,"CAUTION":1},"countByFeatureType":{"Domain":1,"Non-terminal residue":2},"uniParcId":"UPI001936D052"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A7T5V846","uniProtkbId":"A0A7T5V846_9LECA","entryAudit":{"firstPublicDate":"2021-06-02","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2021-06-02","entryVersion":16,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Pseudephebe pubescens","taxonId":172637,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62772.1"}],"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Pezizomycotina","Lecanoromycetes","OSLEUM clade","Lecanoromycetidae","Lecanorales","Lecanorineae","Parmeliaceae","Pseudephebe"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000659"}],"value":"Ribosomal protein"}},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62772.1"}],"value":"L1"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00010531"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000659"}],"value":"Belongs to the universal ribosomal protein uL1 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62772.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":96,"modifier":"EXACT"},"end":{"value":96,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62772.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023274"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000659"}],"id":"KW-0687","category":"Molecular function","name":"Ribonucleoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022980"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000659"}],"id":"KW-0689","category":"Molecular function","name":"Ribosomal protein"}],"references":[{"referenceNumber":1,"citation":{"id":"33242583","citationType":"journal article","authors":["Garrido-Benavent I.","Perez-Ortega S.","de Los Rios A.","Mayrhofer H.","Fernandez-Mendoza F."],"citationCrossReferences":[{"database":"PubMed","id":"33242583"}],"title":"Neogene speciation and Pleistocene expansion of the genus Pseudephebe (Parmeliaceae, lichenized fungi) involving multiple colonizations of Antarctica.","publicationDate":"2020","journal":"Mol. Phylogenet. Evol.","firstPage":"0","lastPage":"0","volume":"107020"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62772.1"}],"value":"I803_hap6","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QQG62772.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MT383883","properties":[{"key":"ProteinId","value":"QQG62772.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A0A7T5V846","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0003723","properties":[{"key":"GoTerm","value":"F:RNA binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"FunFam","id":"3.40.50.790:FF:000002","properties":[{"key":"EntryName","value":"Ribosomal protein"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.790","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050257","properties":[{"key":"EntryName","value":"eL8/uL1-like"}]},{"database":"InterPro","id":"IPR023674","properties":[{"key":"EntryName","value":"Ribosomal_uL1-like"}]},{"database":"InterPro","id":"IPR028364","properties":[{"key":"EntryName","value":"Ribosomal_uL1/biogenesis"}]},{"database":"InterPro","id":"IPR016095","properties":[{"key":"EntryName","value":"Ribosomal_uL1_3-a/b-sand"}]},{"database":"InterPro","id":"IPR023673","properties":[{"key":"EntryName","value":"Ribosomal_uL1_CS"}]},{"database":"PANTHER","id":"PTHR23105","properties":[{"key":"EntryName","value":"RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00687","properties":[{"key":"EntryName","value":"Ribosomal_L1"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56808","properties":[{"key":"EntryName","value":"Ribosomal protein L1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS01199","properties":[{"key":"EntryName","value":"RIBOSOMAL_L1"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"GTIKLPTVPRPNMSICVLGDQHDIDRAKHHGVDAMSSDDLKKLNKNKKLIKKLARKYDAFISSDTLIKQIPRLLGPGLSKAGKFPTPISHNEDLNA","length":96,"molWeight":10582,"crc64":"4BC96FB9C015F2F2","md5":"74909570D87D72F961CFD281E9CC453D"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI001937BAFB"}}]}