{"results":[{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P80998","uniProtkbId":"GVPA_THIPN","entryAudit":{"firstPublicDate":"1997-11-01","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"1997-07-01","entryVersion":74,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Thiocapsa pendens","commonName":"Amoebobacter pendens","taxonId":12934,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Chromatiales","Chromatiaceae","Thiocapsa"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00576"}],"value":"Gas vesicle protein A"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00576"},{"evidenceCode":"ECO:0000303","source":"PubMed","id":"1527496"}],"value":"GvpA"}]},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"1527496"}],"value":"Gas vesicle structural protein"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00576"},{"evidenceCode":"ECO:0000303","source":"PubMed","id":"1527496"}],"value":"gvpA"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00576"}],"value":"Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00576"}],"value":"The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00576"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"1527496"}],"value":"Gas vesicle shell","id":"SL-0126"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00576"}],"value":"Belongs to the gas vesicle GvpA family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":66,"modifier":"OUTSIDE"}},"description":"Gas vesicle protein A","featureId":"PRO_0000199977"},{"type":"Sequence uncertainty","location":{"start":{"value":63,"modifier":"EXACT"},"end":{"value":63,"modifier":"EXACT"}},"description":"L or D"},{"type":"Non-terminal residue","location":{"start":{"value":66,"modifier":"EXACT"},"end":{"value":66,"modifier":"EXACT"}},"description":""}],"keywords":[{"id":"KW-0903","category":"Technical term","name":"Direct protein sequencing"},{"id":"KW-0304","category":"Cellular component","name":"Gas vesicle"}],"references":[{"referenceNumber":1,"citation":{"id":"1527496","citationType":"journal article","authors":["Griffiths A.E.","Walsby A.E.","Hayes P.K."],"citationCrossReferences":[{"database":"PubMed","id":"1527496"},{"database":"DOI","id":"10.1099/00221287-138-6-1243"}],"title":"The homologies of gas vesicle proteins.","publicationDate":"1992","journal":"J. Gen. Microbiol.","firstPage":"1243","lastPage":"1250","volume":"138"},"referencePositions":["PROTEIN SEQUENCE","SUBCELLULAR LOCATION"],"referenceComments":[{"value":"Konstanz 5813","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"AlphaFoldDB","id":"P80998","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P80998","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0033172","properties":[{"key":"GoTerm","value":"C:gas vesicle shell"},{"key":"GoEvidenceType","value":"EXP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"1527496"}]},{"database":"GO","id":"GO:0012506","properties":[{"key":"GoTerm","value":"C:vesicle membrane"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0005198","properties":[{"key":"GoTerm","value":"F:structural molecule activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"InterPro","id":"IPR000638","properties":[{"key":"EntryName","value":"Gas-vesicle_GvpA-like"}]},{"database":"InterPro","id":"IPR050530","properties":[{"key":"EntryName","value":"GvpA"}]},{"database":"InterPro","id":"IPR018493","properties":[{"key":"EntryName","value":"GvpA-like_CS"}]},{"database":"NCBIfam","id":"NF006874","properties":[{"key":"EntryName","value":"gvpA"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR35344:SF4","properties":[{"key":"EntryName","value":"GAS VESICLE PROTEIN A1"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR35344","properties":[{"key":"EntryName","value":"GAS VESICLE STRUCTURAL PROTEIN 2-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00741","properties":[{"key":"EntryName","value":"Gas_vesicle"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00234","properties":[{"key":"EntryName","value":"GAS_VESICLE_A_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00669","properties":[{"key":"EntryName","value":"GAS_VESICLE_A_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"AKVANSTDSSSLAEVIDRILDKGIVIDAWVKVSLVGIELLAIEARVVVASVETYLKYAEAIGLTIP","length":66,"molWeight":6998,"crc64":"EE81C5C8DBCC4F40","md5":"F32855AD8F3BB2818361C85340FC8482"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Sequence uncertainty":1,"Non-terminal residue":1},"uniParcId":"UPI000012BE46"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A9Q6U3","uniProtkbId":"A9Q6U3_THIPN","entryAudit":{"firstPublicDate":"2008-02-05","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-02-05","entryVersion":38,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Thiocapsa pendens","commonName":"Amoebobacter pendens","taxonId":12934,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67347.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Chromatiales","Chromatiaceae","Thiocapsa"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67347.1"}],"value":"Sulfate thioesterase/sulfate thiohydrolase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67347.1"}],"value":"soxB"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362119"}],"value":"Belongs to the 5'-nucleotidase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67347.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":330,"modifier":"EXACT"},"end":{"value":330,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67347.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362119"},{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67347.1"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362119"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"}],"references":[{"referenceNumber":1,"citation":{"id":"17991026","citationType":"journal article","authors":["Meyer B.","Imhoff J.F.","Kuever J."],"citationCrossReferences":[{"database":"PubMed","id":"17991026"},{"database":"DOI","id":"10.1111/j.1462-2920.2007.01407.x"}],"title":"Molecular analysis of the distribution and phylogeny of the soxB gene among sulfur-oxidizing bacteria - evolution of the Sox sulfur oxidation enzyme system.","publicationDate":"2007","journal":"Environ. Microbiol.","firstPage":"2957","lastPage":"2977","volume":"9"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67347.1"}],"value":"DSM 236","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABR67347.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"EF618577","properties":[{"key":"ProteinId","value":"ABR67347.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"A9Q6U3","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0030288","properties":[{"key":"GoTerm","value":"C:outer membrane-bounded periplasmic space"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0016787","properties":[{"key":"GoTerm","value":"F:hydrolase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009166","properties":[{"key":"GoTerm","value":"P:nucleotide catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.60.21.10","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.90.780.10","properties":[{"key":"EntryName","value":"5'-Nucleotidase, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR036907","properties":[{"key":"EntryName","value":"5'-Nucleotdase_C_sf"}]},{"database":"InterPro","id":"IPR006179","properties":[{"key":"EntryName","value":"5_nucleotidase/apyrase"}]},{"database":"InterPro","id":"IPR029052","properties":[{"key":"EntryName","value":"Metallo-depent_PP-like"}]},{"database":"PANTHER","id":"PTHR11575","properties":[{"key":"EntryName","value":"5'-NUCLEOTIDASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11575:SF42","properties":[{"key":"EntryName","value":"SULFUR OXIDATION PROTEIN SOXB"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR01607","properties":[{"key":"EntryName","value":"APYRASEFAMLY"}]},{"database":"SUPFAM","id":"SSF55816","properties":[{"key":"EntryName","value":"5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56300","properties":[{"key":"EntryName","value":"Metallo-dependent phosphatases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"YWTRGMDMVGACNLLGVDVMTGHWEFTYLDEEVIKNIGEFKGDFVAQNVKVREEALFDYRFADFPGFDEDLGRAFKPYTIKEVGGVKVAVVGQAFPYTPIANPQRFMPDWSFGIDDGSMQEVVDRVREEDKPDLVVVLSHNGMDVDLKMASRVTGIDVIFGGHTHDGMPAPTIVENASGKTLVTNAGSNGKFLGVMDLEVKDGKLSDYRYRLLPVFSNLLDPNAEMVEYITGVRAPYKAQLEEDLATAEETLFRRGNFNGTFDQVICDALRKVHDAQISLSPGFRWGTTVLPGQKITMDNVMDQTCITYPETYRREMSGADIKLILEDVC","length":330,"molWeight":36901,"crc64":"87D9EBDEC1C7232B","md5":"57C0D802B64D75EDE8F1DE60B3EB2B8B"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI00016082B2"}}]}