{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"Q0ZA68","uniProtkbId":"Q0ZA68_9ROSI","entryAudit":{"firstPublicDate":"2006-08-22","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2006-08-22","entryVersion":79,"sequenceVersion":1},"annotationScore":4.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABG49114.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012313"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"value":"Peroxidase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012313"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"value":"1.11.1.7"}]}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABG49114.1"}],"value":"POD1"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00002322"}],"value":"Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:56136"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:16240"},{"database":"ChEBI","id":"CHEBI:139520"},{"database":"ChEBI","id":"CHEBI:139521"}],"ecNumber":"1.11.1.7","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00000189"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"NADH + O2 + H(+) = H2O2 + NAD(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:11264"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:15379"},{"database":"ChEBI","id":"CHEBI:16240"},{"database":"ChEBI","id":"CHEBI:57540"},{"database":"ChEBI","id":"CHEBI:57945"}],"ecNumber":"1.6.3.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10012"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"NADPH + O2 + H(+) = H2O2 + NADP(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:11260"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:15379"},{"database":"ChEBI","id":"CHEBI:16240"},{"database":"ChEBI","id":"CHEBI:57783"},{"database":"ChEBI","id":"CHEBI:58349"}],"ecNumber":"1.6.3.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10012"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"Ca(2+)","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:29108"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"value":"Binds 2 calcium ions per subunit."}]}},{"commentType":"COFACTOR","cofactors":[{"name":"heme b","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:60344"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"value":"Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit."}]}},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"value":"Secreted","id":"SL-0243"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006873"}],"value":"Belongs to the peroxidase family. Ascorbate peroxidase subfamily"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"value":"Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00297"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":23,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}]},{"type":"Chain","location":{"start":{"value":24,"modifier":"EXACT"},"end":{"value":332,"modifier":"EXACT"}},"description":"Peroxidase","evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"featureId":"PRO_5005142547"},{"type":"Domain","location":{"start":{"value":30,"modifier":"EXACT"},"end":{"value":331,"modifier":"EXACT"}},"description":"Plant heme peroxidase family profile","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50873"}]},{"type":"Active site","location":{"start":{"value":71,"modifier":"EXACT"},"end":{"value":71,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-1"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10012"}]},{"type":"Binding site","location":{"start":{"value":72,"modifier":"EXACT"},"end":{"value":72,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108","label":"1"}},{"type":"Binding site","location":{"start":{"value":75,"modifier":"EXACT"},"end":{"value":75,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108","label":"1"}},{"type":"Binding site","location":{"start":{"value":77,"modifier":"EXACT"},"end":{"value":77,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108","label":"1"}},{"type":"Binding site","location":{"start":{"value":79,"modifier":"EXACT"},"end":{"value":79,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108","label":"1"}},{"type":"Binding site","location":{"start":{"value":81,"modifier":"EXACT"},"end":{"value":81,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108","label":"1"}},{"type":"Binding site","location":{"start":{"value":93,"modifier":"EXACT"},"end":{"value":93,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108","label":"1"}},{"type":"Binding site","location":{"start":{"value":168,"modifier":"EXACT"},"end":{"value":168,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-2"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00297"}],"ligand":{"name":"substrate"}},{"type":"Binding site","location":{"start":{"value":198,"modifier":"EXACT"},"end":{"value":198,"modifier":"EXACT"}},"description":"axial binding residue","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:60344"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00297"}],"ligand":{"name":"heme b","id":"ChEBI:CHEBI:60344"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":199,"modifier":"EXACT"},"end":{"value":199,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108","label":"2"}},{"type":"Binding site","location":{"start":{"value":250,"modifier":"EXACT"},"end":{"value":250,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108","label":"2"}},{"type":"Binding site","location":{"start":{"value":258,"modifier":"EXACT"},"end":{"value":258,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108","label":"2"}},{"type":"Site","location":{"start":{"value":67,"modifier":"EXACT"},"end":{"value":67,"modifier":"EXACT"}},"description":"Transition state stabilizer","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-4"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00297"}]},{"type":"Disulfide bond","location":{"start":{"value":40,"modifier":"EXACT"},"end":{"value":120,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-5"}]},{"type":"Disulfide bond","location":{"start":{"value":73,"modifier":"EXACT"},"end":{"value":78,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-5"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00297"}]},{"type":"Disulfide bond","location":{"start":{"value":126,"modifier":"EXACT"},"end":{"value":327,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-5"}]},{"type":"Disulfide bond","location":{"start":{"value":205,"modifier":"EXACT"},"end":{"value":237,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-5"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00297"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022837"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"id":"KW-0106","category":"Ligand","name":"Calcium"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023157"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-5"}],"id":"KW-1015","category":"PTM","name":"Disulfide bond"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023180"}],"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022617"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00297"}],"id":"KW-0349","category":"Ligand","name":"Heme"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023324"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"id":"KW-0376","category":"Biological process","name":"Hydrogen peroxide"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600823-3"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022559"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"id":"KW-0575","category":"Molecular function","name":"Peroxidase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"id":"KW-0964","category":"Cellular component","name":"Secreted"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU362060"}],"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-DLEO87H1JI5FK","citationType":"submission","authors":["Lin L.","Pan D.-M.","Guo Z.-X."],"title":"cDNA cloning of peroxidase in pericarp of Dimocarpus longan.","publicationDate":"MAY-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABG49114.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ650638","properties":[{"key":"ProteinId","value":"ABG49114.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"Q0ZA68","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005576","properties":[{"key":"GoTerm","value":"C:extracellular region"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0020037","properties":[{"key":"GoTerm","value":"F:heme binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0005506","properties":[{"key":"GoTerm","value":"F:iron ion binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0140825","properties":[{"key":"GoTerm","value":"F:lactoperoxidase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0016174","properties":[{"key":"GoTerm","value":"F:NAD(P)H oxidase H2O2-forming activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0042744","properties":[{"key":"GoTerm","value":"P:hydrogen peroxide catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006979","properties":[{"key":"GoTerm","value":"P:response to oxidative stress"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"CDD","id":"cd00693","properties":[{"key":"EntryName","value":"secretory_peroxidase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.420.10:FF:000001","properties":[{"key":"EntryName","value":"Peroxidase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.520.10:FF:000001","properties":[{"key":"EntryName","value":"Peroxidase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.520.10","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.420.10","properties":[{"key":"EntryName","value":"Peroxidase, domain 2"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR002016","properties":[{"key":"EntryName","value":"Haem_peroxidase"}]},{"database":"InterPro","id":"IPR010255","properties":[{"key":"EntryName","value":"Haem_peroxidase_sf"}]},{"database":"InterPro","id":"IPR000823","properties":[{"key":"EntryName","value":"Peroxidase_pln"}]},{"database":"InterPro","id":"IPR019794","properties":[{"key":"EntryName","value":"Peroxidases_AS"}]},{"database":"InterPro","id":"IPR019793","properties":[{"key":"EntryName","value":"Peroxidases_heam-ligand_BS"}]},{"database":"InterPro","id":"IPR033905","properties":[{"key":"EntryName","value":"Secretory_peroxidase"}]},{"database":"PANTHER","id":"PTHR31388:SF3","properties":[{"key":"EntryName","value":"PEROXIDASE 72"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR31388","properties":[{"key":"EntryName","value":"PEROXIDASE 72-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00141","properties":[{"key":"EntryName","value":"peroxidase"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00458","properties":[{"key":"EntryName","value":"PEROXIDASE"}]},{"database":"PRINTS","id":"PR00461","properties":[{"key":"EntryName","value":"PLPEROXIDASE"}]},{"database":"SUPFAM","id":"SSF48113","properties":[{"key":"EntryName","value":"Heme-dependent peroxidases"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00435","properties":[{"key":"EntryName","value":"PEROXIDASE_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00436","properties":[{"key":"EntryName","value":"PEROXIDASE_2"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50873","properties":[{"key":"EntryName","value":"PEROXIDASE_4"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MAQFVSFLLFVVSLIAFAPLCFSAKHNNGYLFPEFYDHSCPKAQQIVKSVVAKAVAKEARMAASLLRLHFHDCFVKGCDASLLLDSSGSIISEKRSNPNRNSARGFEVLDDIKSALEKECPHTVSCADILALAARDSTVLTGGPSWEVPLGRRDSRGASLSGSNNNIPAPNNTFQTILTKFKLQGLDIVDLVALSGSHTIGNSRCTSFRQRLYNQSGNGQPDLTLDQSYAAQLRTRCPRSGGDQTLFFLDFVSTTKFDNSYFKLLLASKGLLNSDQVLVTKSKESLDLVKKYAAHNELFLPQFAKSMVKMGNISPLTGSRGEIRKNCRKINS","length":332,"molWeight":36397,"crc64":"771FD63E7B9EBC02","md5":"0791917FC542229B3141DE589DD86A98"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":3,"COFACTOR":2,"SUBCELLULAR LOCATION":1,"SIMILARITY":2,"CAUTION":1},"countByFeatureType":{"Signal":1,"Chain":1,"Domain":1,"Active site":1,"Binding site":11,"Site":1,"Disulfide bond":4},"uniParcId":"UPI0000DAC71F"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A059V8G5","uniProtkbId":"A0A059V8G5_9ROSI","entryAudit":{"firstPublicDate":"2014-09-03","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2014-09-03","entryVersion":28,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89705.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"non-specific serine/threonine protein kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"2.7.11.1"}]}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89705.1"}],"value":"EL1"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00060321"}],"value":"Protein kinase involved in blue light responses (e.g. hypocotyl elongation and flowering) by phosphorylating CRY2 to reduce its stability"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047899"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004496"}],"value":"Cytoplasm","id":"SL-0086"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004123"}],"value":"Nucleus","id":"SL-0191"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00005926"}],"value":"Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":9,"modifier":"EXACT"},"end":{"value":277,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":388,"modifier":"EXACT"},"end":{"value":432,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":388,"modifier":"EXACT"},"end":{"value":405,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":418,"modifier":"EXACT"},"end":{"value":432,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":128,"modifier":"EXACT"},"end":{"value":128,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":38,"modifier":"EXACT"},"end":{"value":38,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022490"}],"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023242"}],"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022553"}],"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-71SOVSF1KH8SV","citationType":"submission","authors":["Chen Y.K.","Lai Z.X.","Lin Y.L."],"title":"Gene cloning of flowering time control family from embryogenic callus in Dimocarpus longan.","publicationDate":"FEB-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89705.1"}],"value":"Embryogenic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89705.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KJ480948","properties":[{"key":"ProteinId","value":"AHZ89705.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A059V8G5","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0004674","properties":[{"key":"GoTerm","value":"F:protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0009785","properties":[{"key":"GoTerm","value":"P:blue light signaling pathway"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0009640","properties":[{"key":"GoTerm","value":"P:photomorphogenesis"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd14125","properties":[{"key":"EntryName","value":"STKc_CK1_delta_epsilon"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000325","properties":[{"key":"EntryName","value":"Casein kinase I isoform delta-like"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050235","properties":[{"key":"EntryName","value":"CK1_Ser-Thr_kinase-like"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR11909","properties":[{"key":"EntryName","value":"CASEIN KINASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDRIVGAKYKLGRKIGSGSFGEIYLATHIDTFEIVAVKIENNKTKHPQLLYEAKLYNILQGGSGIPSIKWSGVDGEDNALVLDLLGPSLEDLFVYCGRKFSLKTVLLLADQMITRIEYVHSKGFLHRDIKPDNFLMGLGRKANQVYIIDFGLAKRYRDATTNRHIPYRENKNLTGTARYASCNTHLGIEQSRRDDLESLGYVLLYFLRGSLPWQGLKAATKKQKYDKICEKKLSTPIEVLCKSHPVEFASYIHYCHSLTFDQRPDYGFLKRLFRDLFSREGYEFDYIFDWTIIKFQQAQKSRNQPRLSPIPGGSTSHAMPMDMNNHQGGINGPYSANVTDNIRSSNVTGPGTRMHLKSAMGRHLNSDYAVDKNIVSDAHLPSTSYSLAGTTRRNVSKPMTSTEAANTGHGHSNKIGPSSSWISSLQRISSAK","length":432,"molWeight":48568,"crc64":"624A9CB27458EAD0","md5":"BA8C636C337FABEC9F33F4FC39E888C1"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":2,"SUBCELLULAR LOCATION":1,"SIMILARITY":2},"countByFeatureType":{"Domain":1,"Region":1,"Compositional bias":2,"Active site":1,"Binding site":1},"uniParcId":"UPI00045F6787"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A059VBR0","uniProtkbId":"A0A059VBR0_9ROSI","entryAudit":{"firstPublicDate":"2014-09-03","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2014-09-03","entryVersion":58,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89697.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"value":"Phytochrome"}}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89697.1"}],"value":"PhyA"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00002479"}],"value":"Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000084-50"}],"value":"Contains one covalently linked phytochromobilin chromophore"}],"commentType":"PTM"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00008235"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"value":"Belongs to the phytochrome family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Domain","location":{"start":{"value":218,"modifier":"EXACT"},"end":{"value":391,"modifier":"EXACT"}},"description":"Phytochrome chromophore attachment site","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50046"}]},{"type":"Domain","location":{"start":{"value":617,"modifier":"EXACT"},"end":{"value":687,"modifier":"EXACT"}},"description":"PAS","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50112"}]},{"type":"Domain","location":{"start":{"value":690,"modifier":"EXACT"},"end":{"value":746,"modifier":"EXACT"}},"description":"PAC","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50113"}]},{"type":"Domain","location":{"start":{"value":750,"modifier":"EXACT"},"end":{"value":802,"modifier":"EXACT"}},"description":"PAS","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50112"}]},{"type":"Domain","location":{"start":{"value":901,"modifier":"EXACT"},"end":{"value":1118,"modifier":"EXACT"}},"description":"Histidine kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50109"}]},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":24,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":14,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Binding site","location":{"start":{"value":323,"modifier":"EXACT"},"end":{"value":323,"modifier":"EXACT"}},"description":"covalent","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:189064"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000084-50"}],"ligand":{"name":"phytochromobilin","id":"ChEBI:CHEBI:189064"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022991"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0157","category":"Ligand","name":"Chromophore"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022543"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0600","category":"Molecular function","name":"Photoreceptor protein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023170"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022606"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0716","category":"Biological process","name":"Sensory transduction"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023163"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0804","category":"Biological process","name":"Transcription"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023015"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0805","category":"Biological process","name":"Transcription regulation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-A6K4KNHQR0IP","citationType":"submission","authors":["Chen Y.K.","Lai Z.X.","Lin Y.L."],"title":"Gene cloning of phytochrome and cryptochrome family from embryogenic callus in Dimocarpus longan.","publicationDate":"FEB-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89697.1"}],"value":"Embryogenic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89697.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KJ480939","properties":[{"key":"ProteinId","value":"AHZ89697.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A059VBR0","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A0A059VBR0","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0000155","properties":[{"key":"GoTerm","value":"F:phosphorelay sensor kinase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009881","properties":[{"key":"GoTerm","value":"F:photoreceptor activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0042803","properties":[{"key":"GoTerm","value":"F:protein homodimerization activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009584","properties":[{"key":"GoTerm","value":"P:detection of visible light"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0017006","properties":[{"key":"GoTerm","value":"P:protein-tetrapyrrole linkage"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009585","properties":[{"key":"GoTerm","value":"P:red, far-red light phototransduction"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006355","properties":[{"key":"GoTerm","value":"P:regulation of DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd16932","properties":[{"key":"EntryName","value":"HATPase_Phy-like"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd00082","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd00130","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"FunFam","id":"3.30.450.20:FF:000039","properties":[{"key":"EntryName","value":"Phytochrome"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.450.270:FF:000001","properties":[{"key":"EntryName","value":"Phytochrome"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.450.270","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.450.40","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.565.10","properties":[{"key":"EntryName","value":"Histidine kinase-like ATPase, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.450.20","properties":[{"key":"EntryName","value":"PAS domain"},{"key":"MatchStatus","value":"3"}]},{"database":"InterPro","id":"IPR003018","properties":[{"key":"EntryName","value":"GAF"}]},{"database":"InterPro","id":"IPR029016","properties":[{"key":"EntryName","value":"GAF-like_dom_sf"}]},{"database":"InterPro","id":"IPR036890","properties":[{"key":"EntryName","value":"HATPase_C_sf"}]},{"database":"InterPro","id":"IPR003594","properties":[{"key":"EntryName","value":"HATPase_dom"}]},{"database":"InterPro","id":"IPR005467","properties":[{"key":"EntryName","value":"His_kinase_dom"}]},{"database":"InterPro","id":"IPR003661","properties":[{"key":"EntryName","value":"HisK_dim/P_dom"}]},{"database":"InterPro","id":"IPR000014","properties":[{"key":"EntryName","value":"PAS"}]},{"database":"InterPro","id":"IPR000700","properties":[{"key":"EntryName","value":"PAS-assoc_C"}]},{"database":"InterPro","id":"IPR035965","properties":[{"key":"EntryName","value":"PAS-like_dom_sf"}]},{"database":"InterPro","id":"IPR013654","properties":[{"key":"EntryName","value":"PAS_2"}]},{"database":"InterPro","id":"IPR013767","properties":[{"key":"EntryName","value":"PAS_fold"}]},{"database":"InterPro","id":"IPR013515","properties":[{"key":"EntryName","value":"PHY_dom"}]},{"database":"InterPro","id":"IPR044767","properties":[{"key":"EntryName","value":"Phy_HATPase-like"}]},{"database":"InterPro","id":"IPR016132","properties":[{"key":"EntryName","value":"Phyto_chromo_attachment"}]},{"database":"InterPro","id":"IPR013516","properties":[{"key":"EntryName","value":"Phyto_chromo_BS"}]},{"database":"InterPro","id":"IPR001294","properties":[{"key":"EntryName","value":"Phytochrome"}]},{"database":"InterPro","id":"IPR012129","properties":[{"key":"EntryName","value":"Phytochrome_A-E"}]},{"database":"InterPro","id":"IPR043150","properties":[{"key":"EntryName","value":"Phytochrome_PHY_sf"}]},{"database":"NCBIfam","id":"TIGR00229","properties":[{"key":"EntryName","value":"sensory_box"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR47876","properties":[{"key":"EntryName","value":"OS08G0260000 PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR47876:SF3","properties":[{"key":"EntryName","value":"PHYTOCHROME 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01590","properties":[{"key":"EntryName","value":"GAF"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02518","properties":[{"key":"EntryName","value":"HATPase_c"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00512","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00989","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"Pfam","id":"PF08446","properties":[{"key":"EntryName","value":"PAS_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00360","properties":[{"key":"EntryName","value":"PHY"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF000084","properties":[{"key":"EntryName","value":"Phytochrome"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR01033","properties":[{"key":"EntryName","value":"PHYTOCHROME"}]},{"database":"SMART","id":"SM00065","properties":[{"key":"EntryName","value":"GAF"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00387","properties":[{"key":"EntryName","value":"HATPase_c"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00388","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00091","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF55874","properties":[{"key":"EntryName","value":"ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55781","properties":[{"key":"EntryName","value":"GAF domain-like"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF55785","properties":[{"key":"EntryName","value":"PYP-like sensor domain (PAS domain)"},{"key":"MatchStatus","value":"3"}]},{"database":"PROSITE","id":"PS50109","properties":[{"key":"EntryName","value":"HIS_KIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50113","properties":[{"key":"EntryName","value":"PAC"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50112","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS00245","properties":[{"key":"EntryName","value":"PHYTOCHROME_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50046","properties":[{"key":"EntryName","value":"PHYTOCHROME_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSTSRPSHSSSNSGRSRHSARVIAQTTVDAKINADFESSGSSFDYSNSVRVTSSAGGDQQPRSDKVTTAYLHHIQKGKQIQPFGCLLALDEKTFKVVAYSENAPEMLTMVSHAVPSVGDHPVLGIGTDIRTIFTASSASALQKALGFGEDSLLNPILVHCKTSGKPFYAIVHRVTGSLIVDFEPVKPYEVPMTAAGALQSYKLAAKAITRLQSSPSGSMGRLCDTMVQEVFELTGYDRVMTYKFHDDDHGEVISEITKPGLEPYLGLHYPATDIPQAARFLFMKNKVRIIVDCHAKHVKVLQDEKLPVDLTLCGSTLRAPHTCHLQYMENMNSIASLVMAVVVNDGDEEGDSPNSAPPLKQKRLWGLVVCHNTTPRFVPFPLRYACEFLAQVFAIHVNKELELENQIIEKNILRTQTLLCDMLMRDAPLGIVSQSPNIMDLVKCDGAALLYNNKIWRLGVTPSEFQLQDIASWLFEYHMDSTGLSTDSLYDAGFPGALALGDVVCGMAAVRISSKDVIFWFRSHTASAIRWGGAKHEPGEKDDGRKMHPRSSFKAFLEVVKTRSLPWKDYEMDAIHSLQLILRNAFKDVETEDVNNKSIHSKLNDLKLEGMKELEAVTSEMVRLIETATVPILAVDVDGLVNGWNTKIAELTGLPVDKAIGKHFLSLVEDSSVDIVRKMLHLALQGHEEKDVEFEIKTHGCRSDAGPISLIVNACASRDLHENVVGVCFVAQDITGQKTVMDKFTRIEGDYKAIVQNPNPLIPPIFGVDEFGWCSEWNPAMAKLTGWKREEVVDKLLLAEVFGTNMACCRLKNQECFVNLGIVLNNAMSGQDPEKVPFGFFARNGKYVDCLLCLSKKLDGEGAITGVFCFLQLASHELQQALHIQRLSEQTAVKRLKALAYIKRQIRNPLSGIIFSRKMLEGTELGVEQKQLLHTSAQCQRQLNKILDDSDLDSIIDGYLDLEMVEFTLHDVLVASISQVMMKSNGKGIRVVNETAEEIMNETLYGDSIRLQQVLADFLSVSVSFTPNGGQLIVSTSLTKDQLGQSVHLARLELRITHAGGGIPEALLDQMFGADGDATEEGISLLISRKLVKLMNGDVQYLREAGKSTFIVTVELAAAHKSQD","length":1124,"molWeight":124006,"crc64":"1E6854DE814D536D","md5":"69AC5F14FECC9890D89C2FE4876D64BA"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"PTM":1,"SIMILARITY":1,"CAUTION":1},"countByFeatureType":{"Domain":5,"Region":1,"Compositional bias":1,"Binding site":1},"uniParcId":"UPI00045F6550"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A059VC47","uniProtkbId":"A0A059VC47_9ROSI","entryAudit":{"firstPublicDate":"2014-09-03","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2014-09-03","entryVersion":58,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89696.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"value":"Phytochrome"}}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89696.1"}],"value":"PhyB"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00002479"}],"value":"Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00011738"}],"value":"Homodimer"}],"commentType":"SUBUNIT"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000084-50"}],"value":"Contains one covalently linked phytochromobilin chromophore"}],"commentType":"PTM"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00008235"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"value":"Belongs to the phytochrome family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Domain","location":{"start":{"value":252,"modifier":"EXACT"},"end":{"value":420,"modifier":"EXACT"}},"description":"Phytochrome chromophore attachment site","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50046"}]},{"type":"Domain","location":{"start":{"value":645,"modifier":"EXACT"},"end":{"value":716,"modifier":"EXACT"}},"description":"PAS","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50112"}]},{"type":"Domain","location":{"start":{"value":779,"modifier":"EXACT"},"end":{"value":831,"modifier":"EXACT"}},"description":"PAS","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50112"}]},{"type":"Domain","location":{"start":{"value":927,"modifier":"EXACT"},"end":{"value":1147,"modifier":"EXACT"}},"description":"Histidine kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50109"}]},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":52,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":17,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":18,"modifier":"EXACT"},"end":{"value":48,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Binding site","location":{"start":{"value":357,"modifier":"EXACT"},"end":{"value":357,"modifier":"EXACT"}},"description":"covalent","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:189064"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000084-50"}],"ligand":{"name":"phytochromobilin","id":"ChEBI:CHEBI:189064"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022991"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0157","category":"Ligand","name":"Chromophore"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022543"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0600","category":"Molecular function","name":"Photoreceptor protein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023170"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022606"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0716","category":"Biological process","name":"Sensory transduction"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023163"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0804","category":"Biological process","name":"Transcription"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023015"},{"evidenceCode":"ECO:0000256","source":"PIRNR","id":"PIRNR000084"}],"id":"KW-0805","category":"Biological process","name":"Transcription regulation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-A6K4KNHQR0IP","citationType":"submission","authors":["Chen Y.K.","Lai Z.X.","Lin Y.L."],"title":"Gene cloning of phytochrome and cryptochrome family from embryogenic callus in Dimocarpus longan.","publicationDate":"FEB-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89696.1"}],"value":"Embryogenic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89696.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KJ480940","properties":[{"key":"ProteinId","value":"AHZ89696.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A059VC47","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A0A059VC47","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0000155","properties":[{"key":"GoTerm","value":"F:phosphorelay sensor kinase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009881","properties":[{"key":"GoTerm","value":"F:photoreceptor activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0042803","properties":[{"key":"GoTerm","value":"F:protein homodimerization activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009584","properties":[{"key":"GoTerm","value":"P:detection of visible light"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0017007","properties":[{"key":"GoTerm","value":"P:protein-bilin linkage"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0009585","properties":[{"key":"GoTerm","value":"P:red, far-red light phototransduction"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006355","properties":[{"key":"GoTerm","value":"P:regulation of DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd16932","properties":[{"key":"EntryName","value":"HATPase_Phy-like"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd00082","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd00130","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"FunFam","id":"1.10.287.130:FF:000029","properties":[{"key":"EntryName","value":"Phytochrome"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.450.20:FF:000034","properties":[{"key":"EntryName","value":"Phytochrome"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.450.20:FF:000039","properties":[{"key":"EntryName","value":"Phytochrome"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.450.270:FF:000001","properties":[{"key":"EntryName","value":"Phytochrome"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.565.10:FF:000044","properties":[{"key":"EntryName","value":"Phytochrome"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.287.130","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.450.270","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.450.40","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.565.10","properties":[{"key":"EntryName","value":"Histidine kinase-like ATPase, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.450.20","properties":[{"key":"EntryName","value":"PAS domain"},{"key":"MatchStatus","value":"3"}]},{"database":"InterPro","id":"IPR003018","properties":[{"key":"EntryName","value":"GAF"}]},{"database":"InterPro","id":"IPR029016","properties":[{"key":"EntryName","value":"GAF-like_dom_sf"}]},{"database":"InterPro","id":"IPR036890","properties":[{"key":"EntryName","value":"HATPase_C_sf"}]},{"database":"InterPro","id":"IPR003594","properties":[{"key":"EntryName","value":"HATPase_dom"}]},{"database":"InterPro","id":"IPR005467","properties":[{"key":"EntryName","value":"His_kinase_dom"}]},{"database":"InterPro","id":"IPR003661","properties":[{"key":"EntryName","value":"HisK_dim/P_dom"}]},{"database":"InterPro","id":"IPR036097","properties":[{"key":"EntryName","value":"HisK_dim/P_sf"}]},{"database":"InterPro","id":"IPR000014","properties":[{"key":"EntryName","value":"PAS"}]},{"database":"InterPro","id":"IPR035965","properties":[{"key":"EntryName","value":"PAS-like_dom_sf"}]},{"database":"InterPro","id":"IPR013654","properties":[{"key":"EntryName","value":"PAS_2"}]},{"database":"InterPro","id":"IPR013767","properties":[{"key":"EntryName","value":"PAS_fold"}]},{"database":"InterPro","id":"IPR013515","properties":[{"key":"EntryName","value":"PHY_dom"}]},{"database":"InterPro","id":"IPR044767","properties":[{"key":"EntryName","value":"Phy_HATPase-like"}]},{"database":"InterPro","id":"IPR016132","properties":[{"key":"EntryName","value":"Phyto_chromo_attachment"}]},{"database":"InterPro","id":"IPR013516","properties":[{"key":"EntryName","value":"Phyto_chromo_BS"}]},{"database":"InterPro","id":"IPR001294","properties":[{"key":"EntryName","value":"Phytochrome"}]},{"database":"InterPro","id":"IPR012129","properties":[{"key":"EntryName","value":"Phytochrome_A-E"}]},{"database":"InterPro","id":"IPR043150","properties":[{"key":"EntryName","value":"Phytochrome_PHY_sf"}]},{"database":"NCBIfam","id":"TIGR00229","properties":[{"key":"EntryName","value":"sensory_box"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR47876","properties":[{"key":"EntryName","value":"OS08G0260000 PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR47876:SF3","properties":[{"key":"EntryName","value":"PHYTOCHROME 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01590","properties":[{"key":"EntryName","value":"GAF"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02518","properties":[{"key":"EntryName","value":"HATPase_c"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00512","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00989","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"Pfam","id":"PF08446","properties":[{"key":"EntryName","value":"PAS_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00360","properties":[{"key":"EntryName","value":"PHY"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF000084","properties":[{"key":"EntryName","value":"Phytochrome"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR01033","properties":[{"key":"EntryName","value":"PHYTOCHROME"}]},{"database":"SMART","id":"SM00065","properties":[{"key":"EntryName","value":"GAF"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00387","properties":[{"key":"EntryName","value":"HATPase_c"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00388","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00091","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF55874","properties":[{"key":"EntryName","value":"ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF81995","properties":[{"key":"EntryName","value":"beta-sandwich domain of Sec23/24"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55781","properties":[{"key":"EntryName","value":"GAF domain-like"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF47384","properties":[{"key":"EntryName","value":"Homodimeric domain of signal transducing histidine kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55785","properties":[{"key":"EntryName","value":"PYP-like sensor domain (PAS domain)"},{"key":"MatchStatus","value":"3"}]},{"database":"PROSITE","id":"PS50109","properties":[{"key":"EntryName","value":"HIS_KIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50112","properties":[{"key":"EntryName","value":"PAS"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS00245","properties":[{"key":"EntryName","value":"PHYTOCHROME_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50046","properties":[{"key":"EntryName","value":"PHYTOCHROME_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MESNSRAANSHHQTPAQSSGTSNTRGGSGTHQQQQQQQQQQQKQQQPQTTESVTVSKAIAQYTVDARLHAVFEQSGESGKSFDYSQSVRTTTSQSVPEQQISAYLSRIQRGGHIQPFGCMIAVDEPSFRVIGYSENAREMLGLTPQSVPNLEKQEILTIGTDIRTLFISSSSVLLEKAFGAREITLLNPIWIHSRNSGRPFYAILHRIDVGIVVDLEPARTEDPALSIAGAVQSQKLAVRAISQLQSLPGGDIKLLCDTVVESVRQLTGYDRVMVYKFHEDEHGEVVAECKRPDLEPYIGLHYPATDIPQASRFLFKQNRVRMIVDCHASPLRVIQDEGLIQPLCLVGSTLRAPHGCHAQYMANMGSIASLAMAVVINGNDEEAIGGRNSTKLWGLVVCHHTSARCIPFPLRYACEFLMQAFGLQLNMELQLSSQLSEKHVLRTQTLLCDMLLRDSPTGIVTQSPSIMDLVKCDGAALYYQGKYCPLGVTPTEAQIKDIVEWLLTFHGDSTGLSTDSLADAGYPKAASLGNAVCGMAVAYITKRDFLFWFRSHTAKEIKWGGAKHHPEDKDDGQRMHPRSSFKAFLEVVKCRSLPWETAEMDAIHSLQLILRDSFKDTQASNSKAVVQAEVGDLELQGVDELSSVAREMVRLIETATAPIFAVDVQGCINGWNAKVAELTGLSVEEAMGKSLVHDLIFKEYEETVDNLLHHALRGEEDKNVEIKLRTFGAENHKKAVFVVVNACSSKDYTNNIVGVCFVGQDITGQKVVMDKFIHIQGDYKAIVHSPNPLIPPIFASDESTCCLEWNTAMEKLTGWSRGEIIGKMIVGEVFGSCCRLKGPDALTKFMIVLHNAFGGQVQKSFRFPFFDRNGKYVQALLTANKRVNMDGQIVGAFCFLQIASHELQQALKVQRQQEKSCFARLKELAYICQEIKNPLSGIRFTNSLLEATDLTEDQKQFLETSAACEKQMMKIIKDVDLESIEDGSLELEKAEFFLGSVINAVVSQVMMLLRERNLQLIRDIPEEIKSLAVFGDQARIQQVLADFLLNMVRYAPTTEGWVEIHVRPTVKQISDGLTVVHTEFRMVCPGEGLPPELVQDMFHGSRWVTQEGLGLSMCRMILKLMNGEVQYIRESERCYFLIILELPMPQRGSKSVVD","length":1155,"molWeight":128542,"crc64":"54B27F1F6BDA6B46","md5":"E1F5F0FDF43BC4F207882D0A521ADCE1"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"PTM":1,"SIMILARITY":1,"CAUTION":1},"countByFeatureType":{"Domain":4,"Region":1,"Compositional bias":2,"Binding site":1},"uniParcId":"UPI00045F6810"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A059VC53","uniProtkbId":"A0A059VC53_9ROSI","entryAudit":{"firstPublicDate":"2014-09-03","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2014-09-03","entryVersion":42,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89706.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89706.1"}],"value":"Early flowering 6"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89706.1"}],"value":"ELF6"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2-oxoglutarate + O2 = N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + formaldehyde + succinate + CO2","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:60228"},{"database":"Rhea","id":"RHEA-COMP:15535"},{"database":"Rhea","id":"RHEA-COMP:15539"},{"database":"ChEBI","id":"CHEBI:15379"},{"database":"ChEBI","id":"CHEBI:16526"},{"database":"ChEBI","id":"CHEBI:16810"},{"database":"ChEBI","id":"CHEBI:16842"},{"database":"ChEBI","id":"CHEBI:30031"},{"database":"ChEBI","id":"CHEBI:61961"},{"database":"ChEBI","id":"CHEBI:61976"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00051751"}]},"physiologicalReactions":[{"directionType":"left-to-right","reactionCrossReference":{"database":"Rhea","id":"RHEA:60229"},"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00051751"}]}]},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2-oxoglutarate + O2 = N(6)-methyl-L-lysyl(27)-[histone H3] + formaldehyde + succinate + CO2","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:60232"},{"database":"Rhea","id":"RHEA-COMP:15539"},{"database":"Rhea","id":"RHEA-COMP:15544"},{"database":"ChEBI","id":"CHEBI:15379"},{"database":"ChEBI","id":"CHEBI:16526"},{"database":"ChEBI","id":"CHEBI:16810"},{"database":"ChEBI","id":"CHEBI:16842"},{"database":"ChEBI","id":"CHEBI:30031"},{"database":"ChEBI","id":"CHEBI:61929"},{"database":"ChEBI","id":"CHEBI:61976"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00050682"}]},"physiologicalReactions":[{"directionType":"left-to-right","reactionCrossReference":{"database":"Rhea","id":"RHEA:60233"},"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00050682"}]}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00537"}],"value":"Nucleus","id":"SL-0191"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009711"}],"value":"Belongs to the JHDM3 histone demethylase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":17,"modifier":"EXACT"},"end":{"value":58,"modifier":"EXACT"}},"description":"JmjN","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51183"}]},{"type":"Domain","location":{"start":{"value":300,"modifier":"EXACT"},"end":{"value":466,"modifier":"EXACT"}},"description":"JmjC","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51184"}]},{"type":"Domain","location":{"start":{"value":1539,"modifier":"EXACT"},"end":{"value":1568,"modifier":"EXACT"}},"description":"C2H2-type","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50157"}]},{"type":"Domain","location":{"start":{"value":1569,"modifier":"EXACT"},"end":{"value":1598,"modifier":"EXACT"}},"description":"C2H2-type","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50157"}]},{"type":"Domain","location":{"start":{"value":1599,"modifier":"EXACT"},"end":{"value":1625,"modifier":"EXACT"}},"description":"C2H2-type","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50157"}]},{"type":"Region","location":{"start":{"value":231,"modifier":"EXACT"},"end":{"value":287,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":563,"modifier":"EXACT"},"end":{"value":587,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":1420,"modifier":"EXACT"},"end":{"value":1448,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":239,"modifier":"EXACT"},"end":{"value":248,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":260,"modifier":"EXACT"},"end":{"value":269,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Binding site","location":{"start":{"value":343,"modifier":"EXACT"},"end":{"value":343,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00538"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875","note":"catalytic"}},{"type":"Binding site","location":{"start":{"value":345,"modifier":"EXACT"},"end":{"value":345,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00538"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875","note":"catalytic"}},{"type":"Binding site","location":{"start":{"value":434,"modifier":"EXACT"},"end":{"value":434,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00538"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875","note":"catalytic"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022853"}],"id":"KW-0156","category":"Molecular function","name":"Chromatin regulator"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022964"}],"id":"KW-0223","category":"Molecular function","name":"Dioxygenase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00538"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00538"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023242"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00537"}],"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023163"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00537"}],"id":"KW-0804","category":"Biological process","name":"Transcription"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023015"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00537"}],"id":"KW-0805","category":"Biological process","name":"Transcription regulation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022833"}],"id":"KW-0862","category":"Ligand","name":"Zinc"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022771"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00042"}],"id":"KW-0863","category":"Domain","name":"Zinc-finger"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-71SOVSF1KH8SV","citationType":"submission","authors":["Chen Y.K.","Lai Z.X.","Lin Y.L."],"title":"Gene cloning of flowering time control family from embryogenic callus in Dimocarpus longan.","publicationDate":"FEB-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89706.1"}],"value":"Embryogenic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AHZ89706.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KJ480949","properties":[{"key":"ProteinId","value":"AHZ89706.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"SMR","id":"A0A059VC53","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0000785","properties":[{"key":"GoTerm","value":"C:chromatin"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0071558","properties":[{"key":"GoTerm","value":"F:histone H3K27me2/H3K27me3 demethylase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0034647","properties":[{"key":"GoTerm","value":"F:histone H3K4me/H3K4me2/H3K4me3 demethylase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0046872","properties":[{"key":"GoTerm","value":"F:metal ion binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0006351","properties":[{"key":"GoTerm","value":"P:DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0040029","properties":[{"key":"GoTerm","value":"P:epigenetic regulation of gene expression"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0010628","properties":[{"key":"GoTerm","value":"P:positive regulation of gene expression"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0006355","properties":[{"key":"GoTerm","value":"P:regulation of DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:2000028","properties":[{"key":"GoTerm","value":"P:regulation of photoperiodism, flowering"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0048580","properties":[{"key":"GoTerm","value":"P:regulation of post-embryonic development"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0009741","properties":[{"key":"GoTerm","value":"P:response to brassinosteroid"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0009826","properties":[{"key":"GoTerm","value":"P:unidimensional cell growth"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"FunFam","id":"3.30.160.60:FF:000747","properties":[{"key":"EntryName","value":"Probable lysine-specific demethylase ELF6"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.160.60","properties":[{"key":"EntryName","value":"Classic Zinc Finger"},{"key":"MatchStatus","value":"3"}]},{"database":"Gene3D","id":"2.60.120.650","properties":[{"key":"EntryName","value":"Cupin"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003347","properties":[{"key":"EntryName","value":"JmjC_dom"}]},{"database":"InterPro","id":"IPR003349","properties":[{"key":"EntryName","value":"JmjN"}]},{"database":"InterPro","id":"IPR013087","properties":[{"key":"EntryName","value":"Zf-C2H2_type"}]},{"database":"InterPro","id":"IPR036236","properties":[{"key":"EntryName","value":"Znf_C2H2_sf"}]},{"database":"PANTHER","id":"PTHR10694","properties":[{"key":"EntryName","value":"LYSINE-SPECIFIC DEMETHYLASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10694:SF45","properties":[{"key":"EntryName","value":"LYSINE-SPECIFIC DEMETHYLASE ELF6"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02373","properties":[{"key":"EntryName","value":"JmjC"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02375","properties":[{"key":"EntryName","value":"JmjN"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00558","properties":[{"key":"EntryName","value":"JmjC"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00545","properties":[{"key":"EntryName","value":"JmjN"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00355","properties":[{"key":"EntryName","value":"ZnF_C2H2"},{"key":"MatchStatus","value":"4"}]},{"database":"SUPFAM","id":"SSF57667","properties":[{"key":"EntryName","value":"beta-beta-alpha zinc fingers"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF51197","properties":[{"key":"EntryName","value":"Clavaminate synthase-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51184","properties":[{"key":"EntryName","value":"JMJC"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51183","properties":[{"key":"EntryName","value":"JMJN"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00028","properties":[{"key":"EntryName","value":"ZINC_FINGER_C2H2_1"},{"key":"MatchStatus","value":"3"}]},{"database":"PROSITE","id":"PS50157","properties":[{"key":"EntryName","value":"ZINC_FINGER_C2H2_2"},{"key":"MatchStatus","value":"3"}]}],"sequence":{"value":"MGNNVEIPCWLEGLPLAPEFRPTDTEFADPIAYISRIEKEASAFGICKIIPPLPKPSKKYVFSNLNKSLSKCPDLGSDVDLPNVSNSSRMGSRDVSNDGGEARGFFTTRHQELGHSVKRTKGMVSNDSLQLGVHKQVWQSGEVYTLEQFESKSKVFARGLLSLIKEVSPLVVEALFWKAASEKPIYVEYANDVPGSGFGEPEGQFRYFHKRRRKVKSWKSYRCRVRDDGKNNEIDTVRSSHNGEATDTSVKDDTKSCLETSNSSKTSSSVPLDDNSQSLRRKGVHGHADVEGTAGWKLSNSPWNLQVIARSPGSLTRFMPDDIPGVTSPMVYIGMLFSWFAWHVEDHELHSMNFLHTGAAKTWYAVPGDYAFAFEEVIRSEAYGGNIDRLAALALLGEKTTLITPEVIVASGIPCCRLVQNPGEFVVTFPRAYHAGFSHGFNCGEAANFGTPQWLKVAKEAAVRRAAMNYLPMLSHQQLLYLLTMSFVSRVPRSLLPGARSSRLRDRQKEEREFLVKKAFIEDILIENNTLSILLGQESSVYAVLWHPDLLPCPSKDIQLTTETDAVSTEPGENVSHGQSEKNNDQNNLLDEMSLYMETLNDLYLDDHDMSCDFQIDSGTLACVACGILGFPFMSVVQLSEQASMELLLTNHDLVHEEPGISESKVAHPFIGIDATVSSSVSEDPSPVPETSVLPKDLPVPSLTKFTKRWNTSSKFLRPRIFCLEHALQVKELLQTKGGANILVICHSDYQKMKAHAAIIAEEIGTPFNYTDVQLDSASQEDLHLIDLAIDDGENDECNEDWTTKLGINLQHCVKVRKNSPSKRVRHALSLGCLFSERSPSSDFSKVTWQSRRCRSKTKLNPPAQSKLCQSIEIKTDEVLGDKSNNVVVKRKEQIIQYSRRKCKLKPDFSVGESSSDGHSRKLLLEEPSAATWDNHNRINSNISSCNIADDGSIFSGLALPPIGMSERLHEIQVLEASRDLSLNYSPSRVADSLATASIVVDSIEQTEIETSKEVKMEGDCMAICKSAEMRENIEDACNPIEKLEISYGETCSSRSIASGDIFVIQKDQVTDNDIMNGACDLASEGQNYIVTERDISMNEVCGAVKSATFNVASPSVERFDVLIEDTVVDNSSMNDKVCDLINDNEVRQNMQVTNDKGNDELLSCHNKLINQPNPASKEESCEDLNNACPGNCMPLHDHVLQESDSAKVINKEHVMSSVRLMNQSGSVSVESSGIPGNECAVADLCDAETPKNEELGLRMCTVRGRKEELVSGSATCMEVDRSSLRSVEGFSDIRRCNCGEEDLCVDVIEMQPKFHTATRTSVDELVSGLQIEANAVSIGTCFEPPNGICAEDKLGRDGSRDIELLEDAQTSNAANEKPNPSSLAAMNQPIPAVIKTYSRTRRESGSREKLFHGNELCSKGNREQESNKATMEDAVSNAGEGRKRNREVELKTEDQVDYSGFIRSPCEGLRPRAASKTEADISKIPKEKPVTKMARRESNVLVPCQDKKKTMKGCYKCDLDGCRMRFETKRELSLHKSNRCPHEGCGKRFSSHKYAIIHQRVHEDDRPLKCPWEGCSMSFKWAWARTEHIRVHTGERPYQCKVEGCGLSFRFVSDISRHRRKTGHYENISS","length":1631,"molWeight":181305,"crc64":"97A17DAF65405DC0","md5":"DCC512F77C51C2209AC688B1D010C07F"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":2,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Domain":5,"Region":3,"Compositional bias":2,"Binding site":3},"uniParcId":"UPI00045F67E9"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A096ZNF9","uniProtkbId":"A0A096ZNF9_9ROSI","entryAudit":{"firstPublicDate":"2015-01-07","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2015-01-07","entryVersion":39,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIS22739.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012297"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"value":"Laccase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012297"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"value":"1.10.3.2"}]},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"value":"Benzenediol:oxygen oxidoreductase"}},{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"value":"Diphenol oxidase"}},{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"value":"Urishiol oxidase"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIS22739.1"}],"value":"Lac7-a"},"synonyms":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIS22740.1"}],"value":"Lac7-b"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"value":"Lignin degradation and detoxification of lignin-derived products"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:11276"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:15379"},{"database":"ChEBI","id":"CHEBI:17594"},{"database":"ChEBI","id":"CHEBI:17977"}],"ecNumber":"1.10.3.2","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00000349"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"Cu cation","evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:23378"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"value":"Binds 4 Cu cations per monomer."}]}},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004271"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"value":"Secreted, extracellular space, apoplast","id":"SL-0019"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00010609"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"value":"Belongs to the multicopper oxidase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":23,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}]},{"type":"Chain","location":{"start":{"value":24,"modifier":"EXACT"},"end":{"value":570,"modifier":"EXACT"}},"description":"Laccase","evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"featureId":"PRO_5007353764"},{"type":"Domain","location":{"start":{"value":32,"modifier":"EXACT"},"end":{"value":146,"modifier":"EXACT"}},"description":"Plastocyanin-like","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF07732"}]},{"type":"Domain","location":{"start":{"value":158,"modifier":"EXACT"},"end":{"value":309,"modifier":"EXACT"}},"description":"Plastocyanin-like","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF00394"}]},{"type":"Domain","location":{"start":{"value":415,"modifier":"EXACT"},"end":{"value":552,"modifier":"EXACT"}},"description":"Plastocyanin-like","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF07731"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022523"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"id":"KW-0052","category":"Cellular component","name":"Apoplast"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023008"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"id":"KW-0186","category":"Ligand","name":"Copper"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023180"}],"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023185"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"id":"KW-0439","category":"Biological process","name":"Lignin degradation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022525"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"id":"KW-0964","category":"Cellular component","name":"Secreted"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU361119"}],"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-A8JFME0F4FH6R","citationType":"submission","authors":["Tian Q.","Lai Z.","Lin Y."],"title":"Cloning of Honghezi protein Laccase 7 (DlLac7) gene from embryogenic callus in Dimocarpus longan.","publicationDate":"JUL-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIS22739.1"}],"value":"Embryogenic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIS22739.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KM103385","properties":[{"key":"ProteinId","value":"AIS22739.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"KM103386","properties":[{"key":"ProteinId","value":"AIS22740.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A096ZNF9","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0048046","properties":[{"key":"GoTerm","value":"C:apoplast"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005507","properties":[{"key":"GoTerm","value":"F:copper ion binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0052716","properties":[{"key":"GoTerm","value":"F:hydroquinone:oxygen oxidoreductase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0046274","properties":[{"key":"GoTerm","value":"P:lignin catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd13849","properties":[{"key":"EntryName","value":"CuRO_1_LCC_plant"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd13875","properties":[{"key":"EntryName","value":"CuRO_2_LCC_plant"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd13897","properties":[{"key":"EntryName","value":"CuRO_3_LCC_plant"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.60.40.420:FF:000049","properties":[{"key":"EntryName","value":"Laccase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.60.40.420:FF:000062","properties":[{"key":"EntryName","value":"Laccase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.60.40.420","properties":[{"key":"EntryName","value":"Cupredoxins - blue copper proteins"},{"key":"MatchStatus","value":"3"}]},{"database":"InterPro","id":"IPR011707","properties":[{"key":"EntryName","value":"Cu-oxidase-like_N"}]},{"database":"InterPro","id":"IPR001117","properties":[{"key":"EntryName","value":"Cu-oxidase_2nd"}]},{"database":"InterPro","id":"IPR011706","properties":[{"key":"EntryName","value":"Cu-oxidase_C"}]},{"database":"InterPro","id":"IPR045087","properties":[{"key":"EntryName","value":"Cu-oxidase_fam"}]},{"database":"InterPro","id":"IPR033138","properties":[{"key":"EntryName","value":"Cu_oxidase_CS"}]},{"database":"InterPro","id":"IPR002355","properties":[{"key":"EntryName","value":"Cu_oxidase_Cu_BS"}]},{"database":"InterPro","id":"IPR008972","properties":[{"key":"EntryName","value":"Cupredoxin"}]},{"database":"InterPro","id":"IPR034288","properties":[{"key":"EntryName","value":"CuRO_1_LCC"}]},{"database":"InterPro","id":"IPR034285","properties":[{"key":"EntryName","value":"CuRO_2_LCC"}]},{"database":"InterPro","id":"IPR034289","properties":[{"key":"EntryName","value":"CuRO_3_LCC"}]},{"database":"InterPro","id":"IPR017761","properties":[{"key":"EntryName","value":"Laccase"}]},{"database":"NCBIfam","id":"TIGR03389","properties":[{"key":"EntryName","value":"laccase"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11709:SF9","properties":[{"key":"EntryName","value":"LACCASE-7"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11709","properties":[{"key":"EntryName","value":"MULTI-COPPER OXIDASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00394","properties":[{"key":"EntryName","value":"Cu-oxidase"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07731","properties":[{"key":"EntryName","value":"Cu-oxidase_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07732","properties":[{"key":"EntryName","value":"Cu-oxidase_3"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF49503","properties":[{"key":"EntryName","value":"Cupredoxins"},{"key":"MatchStatus","value":"3"}]},{"database":"PROSITE","id":"PS00079","properties":[{"key":"EntryName","value":"MULTICOPPER_OXIDASE1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00080","properties":[{"key":"EntryName","value":"MULTICOPPER_OXIDASE2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MARPALLLLCAFVLLAFSSMASAAIVEHSFDVRNLTVRRLCQEQVITAVNGSLPGPTIRVREGDTLVVHVYNKSPYNLTIHWHGVFQLLSAWADGPDMVTQCPIRPGNKYTYRFKITQQEGTLWWHAHVSWLRATVYGALIIRPRAGSSYPFPKPDKEVPILLGEWWNANVIDVENEALASGAGPNISDAYTINGKPGDLYPCSQDQTYKLEVEKGKTYLLRIINAALNNQLFYKVANHKLTVVGVDAEYTKPYVTDVVVIAPGQTTDVLLTADQPVGSYYMAAHPYASQPSIQFDNTTTRGIIVYEGATSAAPVMPVLPPFSDTPTAHKFYSNLTGLVDGPNWVPVPRHVDKRMFVTVGLGLDRCRSRNNATCQGPGGNRFSASMNNASFEFPTRLSMLQAFFFNVNGVYTRNFPVKPPVKFDFTNTSLSNDTNSPLNFAPKSTSVTKLKFNSTVEMVLQNTALIAIENHPMHLHGFNFHVLAQGFGNFDYKRDSKKFNFVNPQRRNTIAVPVGGWAVIRFQANNPGIWLMHCHLDVHLPWGLATAFEVENGPTPSSTLPPPPHDLPQC","length":570,"molWeight":63216,"crc64":"0293C9AB55335EAF","md5":"55A58711507F21F61259499F6F7C8F42"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"COFACTOR":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Signal":1,"Chain":1,"Domain":3},"uniParcId":"UPI000512711F"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A097I4W8","uniProtkbId":"A0A097I4W8_9ROSI","entryAudit":{"firstPublicDate":"2015-01-07","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2015-01-07","entryVersion":46,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIT56194.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"non-specific serine/threonine protein kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"2.7.11.1"}]}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIT56194.1"}],"value":"BAM1"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004251"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004251"}],"value":"Single-pass type I membrane protein","id":"SL-9905"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00008684"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":18,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":19,"modifier":"EXACT"},"end":{"value":1015,"modifier":"EXACT"}},"description":"non-specific serine/threonine protein kinase","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5001930810"},{"type":"Transmembrane","location":{"start":{"value":635,"modifier":"EXACT"},"end":{"value":654,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Domain","location":{"start":{"value":687,"modifier":"EXACT"},"end":{"value":961,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":961,"modifier":"EXACT"},"end":{"value":1015,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":975,"modifier":"EXACT"},"end":{"value":993,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1005,"modifier":"EXACT"},"end":{"value":1015,"modifier":"EXACT"}},"description":"Pro residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":813,"modifier":"EXACT"},"end":{"value":813,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022473"}],"id":"KW-0217","category":"Molecular function","name":"Developmental protein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022782"}],"id":"KW-0221","category":"Biological process","name":"Differentiation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023180"}],"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022614"}],"id":"KW-0433","category":"Domain","name":"Leucine-rich repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023170"},{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIT56194.1"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-6B6R06TR9A2EA","citationType":"submission","authors":["Zhang D.M.","Lai Z."],"title":"Cloning of Honghezi leucine-rich repeat receptor-like serine/threonine-protein kinase BAM1(DlBAM1) gene from embryogenic callus in Dimocarpus longan.","publicationDate":"JUN-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIT56194.1"}],"value":"Embryogenic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIT56194.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KM017507","properties":[{"key":"ProteinId","value":"AIT56194.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A097I4W8","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0004674","properties":[{"key":"GoTerm","value":"F:protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0033612","properties":[{"key":"GoTerm","value":"F:receptor serine/threonine kinase binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0048437","properties":[{"key":"GoTerm","value":"P:floral organ development"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0048229","properties":[{"key":"GoTerm","value":"P:gametophyte development"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0010075","properties":[{"key":"GoTerm","value":"P:regulation of meristem growth"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0009934","properties":[{"key":"GoTerm","value":"P:regulation of meristem structural organization"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"FunFam","id":"1.10.510.10:FF:000201","properties":[{"key":"EntryName","value":"Leucine-rich repeat receptor-like serine/threonine-protein kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000292","properties":[{"key":"EntryName","value":"Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.80.10.10:FF:000570","properties":[{"key":"EntryName","value":"Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.80.10.10:FF:000108","properties":[{"key":"EntryName","value":"Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM3"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.80.10.10","properties":[{"key":"EntryName","value":"Ribonuclease Inhibitor"},{"key":"MatchStatus","value":"3"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR001611","properties":[{"key":"EntryName","value":"Leu-rich_rpt"}]},{"database":"InterPro","id":"IPR003591","properties":[{"key":"EntryName","value":"Leu-rich_rpt_typical-subtyp"}]},{"database":"InterPro","id":"IPR032675","properties":[{"key":"EntryName","value":"LRR_dom_sf"}]},{"database":"InterPro","id":"IPR013210","properties":[{"key":"EntryName","value":"LRR_N_plant-typ"}]},{"database":"InterPro","id":"IPR055414","properties":[{"key":"EntryName","value":"LRR_R13L4/SHOC2-like"}]},{"database":"InterPro","id":"IPR050647","properties":[{"key":"EntryName","value":"Plant_LRR-RLKs"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR001245","properties":[{"key":"EntryName","value":"Ser-Thr/Tyr_kinase_cat_dom"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR48056","properties":[{"key":"EntryName","value":"LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR48056:SF45","properties":[{"key":"EntryName","value":"PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00560","properties":[{"key":"EntryName","value":"LRR_1"},{"key":"MatchStatus","value":"5"}]},{"database":"Pfam","id":"PF23598","properties":[{"key":"EntryName","value":"LRR_14"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF08263","properties":[{"key":"EntryName","value":"LRRNT_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07714","properties":[{"key":"EntryName","value":"PK_Tyr_Ser-Thr"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00369","properties":[{"key":"EntryName","value":"LRR_TYP"},{"key":"MatchStatus","value":"5"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52058","properties":[{"key":"EntryName","value":"L domain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52047","properties":[{"key":"EntryName","value":"RNI-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MRLILLLFLLILLHISDARTVSEYRALLSIKSALSADSQAALSSWNATTSHCTWTGVTCDSRHHVTSLDLRDLNLSGTLSSDVAHLQFLRNLTVAANQFSGPIPPEISQLSALRFLNLSNNVFNGSFPSQLARLANLEVMDLYNNNMTDELPVGVTQLRNLHHLHLGGNFFSGEIPAEYGGWEFLEYLAVSGNELVGKIPPEIGNLTTLRELYIGYYNTYTGGLPPEIGNLSSLVRLDAANCALSGEIPGEIGKLQKLDTLFLQVNGLSGTLARELGNLKSLKSMDLSNNMFTGEIPASFAELKNMTLLNLFRNKLHGAIPEFIGELPKLEVLQLWENNFTGSIPQRLGSNGMLQLLDLSSNKLTGTLPPDMCSGNRLETLITLGNFLFGPIPESLGKCQSLSRIRMGENFLNGSIPKGLFGLPKLTQVELQDNYLTGEFPVTDSISVSLGQITLSNNQLSGSLPASIGNFSGVQKLLLDGNKFSGQIPPEVGSLKQLSKMGFSDNRFSGQIAPEISKCKLLTFVDLSRNELSGVVPNEITGMKILNYLNLSRNHLVGSIPAAIASMQSLTSVDFSYNNLSGLVPGTGQFSYFNYTSFLGNPQLCGPYLGPCKDGVANGTRQPHVKGPLSASLKLLLVIGLLVCSIAFAVAAIIKARSLKKASESRAWKLPAFQRLDFTCDDVLDCLKEDNIIGKGGAGIVYKGAMPNGDQVAVKRLPVMSRGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNHETNLLVYEYMPNGSLGEVLHGKKGGHLHWDTRYKIAVEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVADFGLAKFLQDSGTSECMSAIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELITGRKPVGEFGDGVDIVQWVRKMTDSNVDGVLKILDPRLPTVPLNEVMHVFYVALLCVEEQAVERPTMREVVQILTELPKPPSSKPADSAIPESSPSPATTTLESPNASTKDPKDHQRSGPPQSPPPDLLSI","length":1015,"molWeight":110337,"crc64":"3BB2270C9F63EA84","md5":"E361D3534BB55BD0C2B82F54123BB589"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":2,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Signal":1,"Chain":1,"Transmembrane":1,"Domain":1,"Region":1,"Compositional bias":2,"Active site":1},"uniParcId":"UPI00051F7CE7"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A0E3T4L5","uniProtkbId":"A0A0E3T4L5_9ROSI","entryAudit":{"firstPublicDate":"2015-06-24","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2015-06-24","entryVersion":38,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AKC01525.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"non-specific serine/threonine protein kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"2.7.11.1"}]}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AKC01525.1"}],"value":"KIN10b"}}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047899"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006234"}],"value":"Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":18,"modifier":"EXACT"},"end":{"value":270,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Domain","location":{"start":{"value":291,"modifier":"EXACT"},"end":{"value":331,"modifier":"EXACT"}},"description":"UBA","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50030"}]},{"type":"Domain","location":{"start":{"value":465,"modifier":"EXACT"},"end":{"value":513,"modifier":"EXACT"}},"description":"KA1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50032"}]},{"type":"Active site","location":{"start":{"value":141,"modifier":"EXACT"},"end":{"value":141,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":47,"modifier":"EXACT"},"end":{"value":47,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023160"}],"id":"KW-0275","category":"Biological process","name":"Fatty acid biosynthesis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023160"}],"id":"KW-0276","category":"Biological process","name":"Fatty acid metabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023160"}],"id":"KW-0444","category":"Biological process","name":"Lipid biosynthesis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023160"}],"id":"KW-0443","category":"Biological process","name":"Lipid metabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023063"}],"id":"KW-0534","category":"Biological process","name":"Nitrate assimilation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022843"}],"id":"KW-0832","category":"PTM","name":"Ubl conjugation"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-74L1PSMT1IBJ8","citationType":"submission","authors":["Dong H.","Tian Q.","Lin Y.","Lai Z."],"title":"Gene cloning of SNF-1 related protein kinase KIN10 (Dl-KIN10b) from embryogenic callus in Dimocarpus longan.","publicationDate":"NOV-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AKC01525.1"}],"value":"Embryogenic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AKC01525.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KP208674","properties":[{"key":"ProteinId","value":"AKC01525.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A0E3T4L5","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0009507","properties":[{"key":"GoTerm","value":"C:chloroplast"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0019900","properties":[{"key":"GoTerm","value":"F:kinase binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0106310","properties":[{"key":"GoTerm","value":"F:protein serine kinase activity"},{"key":"GoEvidenceType","value":"IEA:RHEA"}]},{"database":"GO","id":"GO:0004674","properties":[{"key":"GoTerm","value":"F:protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0035556","properties":[{"key":"GoTerm","value":"P:intracellular signal transduction"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0009743","properties":[{"key":"GoTerm","value":"P:response to carbohydrate"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd12122","properties":[{"key":"EntryName","value":"AMPKA_C"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd14079","properties":[{"key":"EntryName","value":"STKc_AMPK_alpha"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd14335","properties":[{"key":"EntryName","value":"UBA_SnRK1_plant"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000204","properties":[{"key":"EntryName","value":"Non-specific serine/threonine protein kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.310.80:FF:000006","properties":[{"key":"EntryName","value":"Non-specific serine/threonine protein kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.310.80","properties":[{"key":"EntryName","value":"Kinase associated domain 1, KA1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR028375","properties":[{"key":"EntryName","value":"KA1/Ssp2_C"}]},{"database":"InterPro","id":"IPR001772","properties":[{"key":"EntryName","value":"KA1_dom"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"InterPro","id":"IPR015940","properties":[{"key":"EntryName","value":"UBA"}]},{"database":"InterPro","id":"IPR009060","properties":[{"key":"EntryName","value":"UBA-like_sf"}]},{"database":"PANTHER","id":"PTHR24346:SF82","properties":[{"key":"EntryName","value":"KP78A-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR24346","properties":[{"key":"EntryName","value":"MAP/MICROTUBULE AFFINITY-REGULATING KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02149","properties":[{"key":"EntryName","value":"KA1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00627","properties":[{"key":"EntryName","value":"UBA"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00165","properties":[{"key":"EntryName","value":"UBA"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF103243","properties":[{"key":"EntryName","value":"KA1-like"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF46934","properties":[{"key":"EntryName","value":"UBA-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50032","properties":[{"key":"EntryName","value":"KA1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50030","properties":[{"key":"EntryName","value":"UBA"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDGSNRGSGGVDMILPNYKLGKTLGIGSFGKVKIAEHALTGHKVAIKILNRRKIRNMEMEEKVRREIKILRLFMHPHIIRLYEVIETQSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVVEPMKRITIPDIRQHPWFQAHLPRYLAVPPPDTMQQAKKIDEEILKEVVKMGFAQNQVIESLRNRMQNEATVAYYLLLDNRFRVSSGYLGAEFQETMESSFNRMHPSEAGAPAVGQRLPGYMDYQGISMRAQGGFERKWALGLQSRAHPREIMTEVLKALQELNVGWKKIGHYNMKCRWIPGIPGHHEGMAKNPVHSNHYFGDESTIIENDGPIKSPNVVKFEVQLYKTREEKYLLDLQRVQGPQFLFLDLCAAFLAQLRVL","length":514,"molWeight":58640,"crc64":"C586B9794C5EAC4A","md5":"C1EC295EE25D66E0FAFF39F502CC3A2B"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":2,"SIMILARITY":2},"countByFeatureType":{"Domain":3,"Active site":1,"Binding site":1},"uniParcId":"UPI0006190046"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A0K0LG79","uniProtkbId":"A0A0K0LG79_9ROSI","entryAudit":{"firstPublicDate":"2015-11-11","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2015-11-11","entryVersion":42,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AJA30443.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU004561"}],"value":"Auxin response factor"}}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AJA30443.1"}],"value":"ARF16"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00037697"}],"value":"Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00011726"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU004561"}],"value":"Homodimers and heterodimers"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004123"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU004561"}],"value":"Nucleus","id":"SL-0191"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00007853"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU004561"}],"value":"Belongs to the ARF family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":121,"modifier":"EXACT"},"end":{"value":223,"modifier":"EXACT"}},"description":"TF-B3","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50863"}]},{"type":"Domain","location":{"start":{"value":601,"modifier":"EXACT"},"end":{"value":681,"modifier":"EXACT"}},"description":"PB1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51745"}]},{"type":"DNA binding","location":{"start":{"value":121,"modifier":"EXACT"},"end":{"value":223,"modifier":"EXACT"}},"description":"TF-B3","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"}]},{"type":"Region","location":{"start":{"value":539,"modifier":"EXACT"},"end":{"value":592,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":539,"modifier":"EXACT"},"end":{"value":585,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023294"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU004561"}],"id":"KW-0927","category":"Biological process","name":"Auxin signaling pathway"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023125"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"}],"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AJA30443.1"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023242"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"}],"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023163"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"}],"id":"KW-0804","category":"Biological process","name":"Transcription"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023015"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"}],"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-A40QPQGOFC898","citationType":"submission","authors":["Zhao L.X."],"title":"Cloning and sequence analysis of the sulfate transporter cDNA in Reaumuria trigyna Maxim.","publicationDate":"JAN-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AJA30443.1"}],"value":"Embryogenic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AJA30443.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KJ410235","properties":[{"key":"ProteinId","value":"AJA30443.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A0K0LG79","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A0A0K0LG79","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0003677","properties":[{"key":"GoTerm","value":"F:DNA binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0051301","properties":[{"key":"GoTerm","value":"P:cell division"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0006351","properties":[{"key":"GoTerm","value":"P:DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0007389","properties":[{"key":"GoTerm","value":"P:pattern specification process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0006355","properties":[{"key":"GoTerm","value":"P:regulation of DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0009733","properties":[{"key":"GoTerm","value":"P:response to auxin"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0048829","properties":[{"key":"GoTerm","value":"P:root cap development"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd10017","properties":[{"key":"EntryName","value":"B3_DNA"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.30.30.1040:FF:000002","properties":[{"key":"EntryName","value":"Auxin response factor"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.40.330.10:FF:000001","properties":[{"key":"EntryName","value":"Auxin response factor"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.30.30.1040","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.40.330.10","properties":[{"key":"EntryName","value":"DNA-binding pseudobarrel domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.10.20.90","properties":[{"key":"EntryName","value":"Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR010525","properties":[{"key":"EntryName","value":"ARF_dom"}]},{"database":"InterPro","id":"IPR044835","properties":[{"key":"EntryName","value":"ARF_plant"}]},{"database":"InterPro","id":"IPR003340","properties":[{"key":"EntryName","value":"B3_DNA-bd"}]},{"database":"InterPro","id":"IPR015300","properties":[{"key":"EntryName","value":"DNA-bd_pseudobarrel_sf"}]},{"database":"InterPro","id":"IPR053793","properties":[{"key":"EntryName","value":"PB1-like"}]},{"database":"PANTHER","id":"PTHR31384:SF160","properties":[{"key":"EntryName","value":"AUXIN RESPONSE FACTOR 16"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR31384","properties":[{"key":"EntryName","value":"AUXIN RESPONSE FACTOR 4-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF06507","properties":[{"key":"EntryName","value":"ARF_AD"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02362","properties":[{"key":"EntryName","value":"B3"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM01019","properties":[{"key":"EntryName","value":"B3"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF101936","properties":[{"key":"EntryName","value":"DNA-binding pseudobarrel domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50863","properties":[{"key":"EntryName","value":"B3"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51745","properties":[{"key":"EntryName","value":"PB1"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MIRVMDSSKNSSIKKNSTESCLDAQLWHACAGGMVQMPPINSKVVYFPQGHLEHAKGNNTELSNLHIPCMIPCRVSAIKYMADTETDEVYAKIRLISLKNNGLDDFEDVGNGECGEKPPSFAKTLTQSDANNGGGFSVPRYCAETIFPRLDYSAEPPVQTILAKDVHGEVWKFRHIYRGTPRRHLLTTGWSNFVNQKKLVAGDSIVFLRADNGDLCVGIRRAKKGGIGGGSDYSLVGSWNSSGFPFAGGYSVYVREDDSKLMRRNSNTDFRANVSADSVVQAATLAANAQPFEVVYYPRASTPEFVVKASAVRAAMQIQWCSGMRFKMAFETEDSSRISWFMGTISSVQVADPIRWRNSPWRLLQVAWDEPDLLQNVKRVNPWLVELVSSIPAIHLSTFSPPRKRLRLPEQPDFPLINQVPMPSFSRNPVMISSPLGCVADSTPAGIQGARHAQYGPSLSDLHFNKLQSGQFPVGFQHHHHPTPPPRIPSCNFISDTENNDNISCLLTMGNPTHSFKENNETKTPHILLFGQLILPQQNSSQSCSGDTLGNSSSDGNPEKTVISSDGSGSAVHQNGPLENSSNEGSPWCKDHRKSDVSLETGHCKVFVESEDVGRTLNLSVLGSYEELYGKLANMFGIESSEMFSNVLYRDAAGSTKHTGDEPFSDFLKTARRLTIFTDSSSDNVGR","length":687,"molWeight":75637,"crc64":"DCE7023B0FF1D50F","md5":"4847C4FE9691EDB57839C2D8AFA840F1"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Domain":2,"DNA binding":1,"Region":1,"Compositional bias":1},"uniParcId":"UPI0006BC909D"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A0K0LG98","uniProtkbId":"A0A0K0LG98_9ROSI","entryAudit":{"firstPublicDate":"2015-11-11","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2015-11-11","entryVersion":42,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AJA30442.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU004561"}],"value":"Auxin response factor"}},"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AJA30442.1"}],"value":"ARF10"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00037697"}],"value":"Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00011726"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU004561"}],"value":"Homodimers and heterodimers"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004123"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU004561"}],"value":"Nucleus","id":"SL-0191"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00007853"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU004561"}],"value":"Belongs to the ARF family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":117,"modifier":"EXACT"},"end":{"value":219,"modifier":"EXACT"}},"description":"TF-B3","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50863"}]},{"type":"Domain","location":{"start":{"value":613,"modifier":"EXACT"},"end":{"value":693,"modifier":"EXACT"}},"description":"PB1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51745"}]},{"type":"DNA binding","location":{"start":{"value":117,"modifier":"EXACT"},"end":{"value":219,"modifier":"EXACT"}},"description":"TF-B3","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"}]},{"type":"Region","location":{"start":{"value":562,"modifier":"EXACT"},"end":{"value":587,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":575,"modifier":"EXACT"},"end":{"value":584,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Non-terminal residue","location":{"start":{"value":698,"modifier":"EXACT"},"end":{"value":698,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AJA30442.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023294"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU004561"}],"id":"KW-0927","category":"Biological process","name":"Auxin signaling pathway"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023125"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"}],"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AJA30442.1"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023242"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"}],"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023163"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"}],"id":"KW-0804","category":"Biological process","name":"Transcription"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023015"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00326"}],"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-A40QPQGOFC898","citationType":"submission","authors":["Zhao L.X."],"title":"Cloning and sequence analysis of the sulfate transporter cDNA in Reaumuria trigyna Maxim.","publicationDate":"JAN-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AJA30442.1"}],"value":"Embryogenic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AJA30442.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KJ410234","properties":[{"key":"ProteinId","value":"AJA30442.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A0K0LG98","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0003677","properties":[{"key":"GoTerm","value":"F:DNA binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0051301","properties":[{"key":"GoTerm","value":"P:cell division"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0006351","properties":[{"key":"GoTerm","value":"P:DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0007389","properties":[{"key":"GoTerm","value":"P:pattern specification process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0006355","properties":[{"key":"GoTerm","value":"P:regulation of DNA-templated transcription"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0009733","properties":[{"key":"GoTerm","value":"P:response to auxin"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0048829","properties":[{"key":"GoTerm","value":"P:root cap development"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd10017","properties":[{"key":"EntryName","value":"B3_DNA"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.30.30.1040:FF:000002","properties":[{"key":"EntryName","value":"Auxin response factor"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.40.330.10:FF:000001","properties":[{"key":"EntryName","value":"Auxin response factor"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.30.30.1040","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.40.330.10","properties":[{"key":"EntryName","value":"DNA-binding pseudobarrel domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.10.20.90","properties":[{"key":"EntryName","value":"Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR010525","properties":[{"key":"EntryName","value":"ARF_dom"}]},{"database":"InterPro","id":"IPR044835","properties":[{"key":"EntryName","value":"ARF_plant"}]},{"database":"InterPro","id":"IPR003340","properties":[{"key":"EntryName","value":"B3_DNA-bd"}]},{"database":"InterPro","id":"IPR015300","properties":[{"key":"EntryName","value":"DNA-bd_pseudobarrel_sf"}]},{"database":"InterPro","id":"IPR053793","properties":[{"key":"EntryName","value":"PB1-like"}]},{"database":"PANTHER","id":"PTHR31384:SF39","properties":[{"key":"EntryName","value":"AUXIN RESPONSE FACTOR"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR31384","properties":[{"key":"EntryName","value":"AUXIN RESPONSE FACTOR 4-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF06507","properties":[{"key":"EntryName","value":"ARF_AD"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02362","properties":[{"key":"EntryName","value":"B3"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM01019","properties":[{"key":"EntryName","value":"B3"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF101936","properties":[{"key":"EntryName","value":"DNA-binding pseudobarrel domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50863","properties":[{"key":"EntryName","value":"B3"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51745","properties":[{"key":"EntryName","value":"PB1"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MITFMDSKEKVKDMDKCLDSRLWHACAGGMVQMPPVNSKVFYFPQGHAEHACGPVDFRNCPRIPPYILCRVSAIKFMADPETDEVFAKIKLIPISNNEPGFDDDVILNREQEKPPSFAKTLTQSDANNGGGFSVPRYCAETIFPRLDYSADPPVQTILAKDVHGETWKFRHIYRGTPRRHLLTTGWSTFVNHKKLVAGDSIVFLRAENGDLCVGIRRAKRGIGGGPEVSSGWNGNCVSPYGGFTAFLREDDGKLMRNGNGNVNGSSSHSGNGGLMGKGKVRPESVIEAATLAANRQPFEVVYYPRASTPEFCVKASLVKAALQIRWCSGMRFKMAFEAEDSSRISWFMGTISSVLVSDALYWPDSPWRLLQVTWDEPDLLQNVKRVSPWLVELVSNMPAFHLSTFSPPRKKTRLPQHPDFPLDGQLPMPTFPGNLLGHNSPFGCLPDNTPAGMQGAWHAHYGLSLSDHHLNKLQSGLFSAGFVPLDRAAPPKRASSSPIIQKPSMSENVSCLLTMAHSTQTSKKPDDAKTPQLVLFGQPILTEQQMSLSCSGDTVSPVLTGNSSSEGNLDKMANFSDNSGSAVHQQGLPERSFCEGLQWYKDNRQETDPNLETGHCKVFMESEDVGRTLNLSLLGSYDELYKKLADMFGIENPETLSHVLYRDITGAVKHIGDEPFSDFMKAARRVTILMDSSSDNVG","length":698,"molWeight":77027,"crc64":"B05569BBA3A0C93E","md5":"A695569BD1AEB5146D934CA959AAFC22"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Domain":2,"DNA binding":1,"Region":1,"Compositional bias":1,"Non-terminal residue":1},"uniParcId":"UPI0006BC814D"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A172ZA72","uniProtkbId":"A0A172ZA72_9ROSI","entryAudit":{"firstPublicDate":"2016-09-07","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2016-09-07","entryVersion":30,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ANF89411.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003975"}],"value":"Lipoxygenase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003975"}],"value":"1.13.11.-"}]}},"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003975"}],"value":"Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"value":"Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure"}],"commentType":"FUNCTION"},{"commentType":"COFACTOR","cofactors":[{"name":"Fe cation","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:24875"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"value":"Binds 1 Fe cation per subunit."}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003975"}],"value":"Lipid metabolism; oxylipin biosynthesis"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009419"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003974"}],"value":"Belongs to the lipoxygenase family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00152"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Domain","location":{"start":{"value":45,"modifier":"EXACT"},"end":{"value":171,"modifier":"EXACT"}},"description":"PLAT","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50095"}]},{"type":"Domain","location":{"start":{"value":174,"modifier":"EXACT"},"end":{"value":872,"modifier":"EXACT"}},"description":"Lipoxygenase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51393"}]},{"type":"Region","location":{"start":{"value":237,"modifier":"EXACT"},"end":{"value":262,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":249,"modifier":"EXACT"},"end":{"value":262,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Binding site","location":{"start":{"value":533,"modifier":"EXACT"},"end":{"value":533,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600907-1"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875","note":"catalytic"}},{"type":"Binding site","location":{"start":{"value":538,"modifier":"EXACT"},"end":{"value":538,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600907-1"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875","note":"catalytic"}},{"type":"Binding site","location":{"start":{"value":724,"modifier":"EXACT"},"end":{"value":724,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600907-1"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875","note":"catalytic"}},{"type":"Binding site","location":{"start":{"value":728,"modifier":"EXACT"},"end":{"value":728,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600907-1"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875","note":"catalytic"}},{"type":"Binding site","location":{"start":{"value":872,"modifier":"EXACT"},"end":{"value":872,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600907-1"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875","note":"catalytic"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022964"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0223","category":"Molecular function","name":"Dioxygenase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023160"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0275","category":"Biological process","name":"Fatty acid biosynthesis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022832"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0276","category":"Biological process","name":"Fatty acid metabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600907-1"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022516"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0444","category":"Biological process","name":"Lipid biosynthesis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023098"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0443","category":"Biological process","name":"Lipid metabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600907-1"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022767"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00726"}],"id":"KW-0925","category":"Biological process","name":"Oxylipin biosynthesis"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-70LBH6MK02EQ4","citationType":"submission","authors":["Liu W.H.","Shuai L.","Qian P.H.","Han D.M.","Wu Z.X."],"title":"cloning and expression of lipoxygenase genes and enzyme activity during postharvest senescence of longan (Dimocarpus longan Lour.).","publicationDate":"DEC-2015","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ANF89411.1"}],"value":"Pericarp","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ANF89411.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KU243373","properties":[{"key":"ProteinId","value":"ANF89411.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A172ZA72","properties":[{"key":"Description","value":"-"}]},{"database":"UniPathway","id":"UPA00382","properties":[{"key":"RectionId","value":"-"}]},{"database":"GO","id":"GO:0005506","properties":[{"key":"GoTerm","value":"F:iron ion binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0016702","properties":[{"key":"GoTerm","value":"F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0006633","properties":[{"key":"GoTerm","value":"P:fatty acid biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0034440","properties":[{"key":"GoTerm","value":"P:lipid oxidation"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0031408","properties":[{"key":"GoTerm","value":"P:oxylipin biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0099402","properties":[{"key":"GoTerm","value":"P:plant organ development"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0009791","properties":[{"key":"GoTerm","value":"P:post-embryonic development"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd01751","properties":[{"key":"EntryName","value":"PLAT_LH2"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.20.245.10:FF:000002","properties":[{"key":"EntryName","value":"Lipoxygenase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.10.450.60:FF:000002","properties":[{"key":"EntryName","value":"Lipoxygenase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"4.10.372.10:FF:000001","properties":[{"key":"EntryName","value":"Lipoxygenase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"4.10.375.10:FF:000001","properties":[{"key":"EntryName","value":"Lipoxygenase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.10.450.60","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"4.10.375.10","properties":[{"key":"EntryName","value":"Lipoxygenase-1, Domain 2"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"4.10.372.10","properties":[{"key":"EntryName","value":"Lipoxygenase-1, Domain 3"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.245.10","properties":[{"key":"EntryName","value":"Lipoxygenase-1, Domain 5"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.60.60.20","properties":[{"key":"EntryName","value":"PLAT/LH2 domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR000907","properties":[{"key":"EntryName","value":"LipOase"}]},{"database":"InterPro","id":"IPR013819","properties":[{"key":"EntryName","value":"LipOase_C"}]},{"database":"InterPro","id":"IPR036226","properties":[{"key":"EntryName","value":"LipOase_C_sf"}]},{"database":"InterPro","id":"IPR020834","properties":[{"key":"EntryName","value":"LipOase_CS"}]},{"database":"InterPro","id":"IPR020833","properties":[{"key":"EntryName","value":"LipOase_Fe_BS"}]},{"database":"InterPro","id":"IPR001246","properties":[{"key":"EntryName","value":"LipOase_plant"}]},{"database":"InterPro","id":"IPR042057","properties":[{"key":"EntryName","value":"Lipoxy_PLAT/LH2"}]},{"database":"InterPro","id":"IPR027433","properties":[{"key":"EntryName","value":"Lipoxygenase_dom_3"}]},{"database":"InterPro","id":"IPR001024","properties":[{"key":"EntryName","value":"PLAT/LH2_dom"}]},{"database":"InterPro","id":"IPR036392","properties":[{"key":"EntryName","value":"PLAT/LH2_dom_sf"}]},{"database":"PANTHER","id":"PTHR11771","properties":[{"key":"EntryName","value":"LIPOXYGENASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00305","properties":[{"key":"EntryName","value":"Lipoxygenase"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01477","properties":[{"key":"EntryName","value":"PLAT"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00087","properties":[{"key":"EntryName","value":"LIPOXYGENASE"}]},{"database":"PRINTS","id":"PR00468","properties":[{"key":"EntryName","value":"PLTLPOXGNASE"}]},{"database":"SMART","id":"SM00308","properties":[{"key":"EntryName","value":"LH2"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF49723","properties":[{"key":"EntryName","value":"Lipase/lipooxygenase domain (PLAT/LH2 domain)"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF48484","properties":[{"key":"EntryName","value":"Lipoxigenase"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00711","properties":[{"key":"EntryName","value":"LIPOXYGENASE_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00081","properties":[{"key":"EntryName","value":"LIPOXYGENASE_2"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51393","properties":[{"key":"EntryName","value":"LIPOXYGENASE_3"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50095","properties":[{"key":"EntryName","value":"PLAT"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MIHSVIEKITGGDQNGSKKLEMGGSQSRKIKGTVVLMKKNVLDFNDFHASLLDRVHELLGKGVSLQLVSAVHGDSQANGVHGKVGKPAYLKDWITRITPLAAGESAFKVIFDADEEIGVPGAFIVKNNHHSEFYLKTLTLDEVPGHGRMHFVCNSWVYPAKYYKYDRVFFTNQTYLPSETPTPLRYYREQELFNLRGDGSDEELKEYDRVYDYAYYNDLGNPDKGAEYARPILGGSAEYPYPRRGRTSRPPTKSDPNTESRLPITSSLNIYVPRDERFGHLKMSDFLGYALKSIAQFIKPALESFDSTPNEFDSFDEVQKLYEGGLDLPDSHLLDDIRRNIPLELLKEIFQTDGARLFEYPMPQVIRNNRTAWRTDEEFAREMLAGVNPVIIRRLEEFPPTSKLDSKLYGNQNSTITAKHIEGNLDGVTIEEALKNNRLFILDHHDILMPYLRRINTTTTKTYASRTILFLKDDGTLKPLVIELSRPHDKGDQFGADSKVYTPAEHGVEGSIWQLAKAYVAVNDSGVHQLISHWLNTHAAIEPFVIATNRQLSVLHPIYKLLHPHFRDTMNINAFARQILINGGGILEITVFPAKYAMEMSSVVYKNWVFTEQALPEDLKNRGVAVEDPNSPHGLRLLIEDYPYAVDGLEIWSAIKKWVEDYCSFYYKSDEMVQKDAELQNWWRELREEGHGDKKNEPWWPKMHTRKELIDSCTIIIWVASALHAAVNFGQYPYAGFLPNRPTISRKFMPEEGTPEYAELEKNPDKAFLRTITAQLQTLLGIPLIEILSRHSTDEVYLGQRATPEWTLDHQPLQAFQEFGNTLAKIEKRILALNNDKKLKNRVGPVEMPYTLLYPTSEGGLTGKGIPNSVSI","length":872,"molWeight":99313,"crc64":"853CE4C4279C1717","md5":"1588D2C911D3E0E8F90FD1BD1D9DFDB5"},"extraAttributes":{"countByCommentType":{"FUNCTION":2,"COFACTOR":1,"PATHWAY":1,"SIMILARITY":1,"CAUTION":1},"countByFeatureType":{"Domain":2,"Region":1,"Compositional bias":1,"Binding site":5},"uniParcId":"UPI0007DDCB73"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A1B0Z300","uniProtkbId":"A0A1B0Z300_9ROSI","entryAudit":{"firstPublicDate":"2016-11-02","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2016-11-02","entryVersion":36,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ANO58602.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU365040"}],"value":"Glutathione reductase"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU365040"}],"value":"GRase"}],"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU365040"}],"value":"1.8.1.7"}]}},"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU365040"}],"value":"Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH)"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:11740"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:57783"},{"database":"ChEBI","id":"CHEBI:57925"},{"database":"ChEBI","id":"CHEBI:58297"},{"database":"ChEBI","id":"CHEBI:58349"}],"ecNumber":"1.8.1.7","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00049142"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU365040"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"FAD","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-3"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:57692"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-3"}],"value":"Binds 1 FAD per subunit."}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00011738"}],"value":"Homodimer"}],"commentType":"SUBUNIT"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00007532"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003691"}],"value":"Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":76,"modifier":"EXACT"},"end":{"value":398,"modifier":"EXACT"}},"description":"FAD/NAD(P)-binding","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF07992"}]},{"type":"Domain","location":{"start":{"value":418,"modifier":"EXACT"},"end":{"value":526,"modifier":"EXACT"}},"description":"Pyridine nucleotide-disulphide oxidoreductase dimerisation","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF02852"}]},{"type":"Region","location":{"start":{"value":532,"modifier":"EXACT"},"end":{"value":553,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":516,"modifier":"EXACT"},"end":{"value":516,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-2"}]},{"type":"Binding site","location":{"start":{"value":131,"modifier":"EXACT"},"end":{"value":131,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:57692"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-3"}],"ligand":{"name":"FAD","id":"ChEBI:CHEBI:57692"}},{"type":"Binding site","location":{"start":{"value":195,"modifier":"EXACT"},"end":{"value":195,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:57692"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-3"}],"ligand":{"name":"FAD","id":"ChEBI:CHEBI:57692"}},{"type":"Binding site","location":{"start":{"value":254,"modifier":"EXACT"},"end":{"value":261,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:57540"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-3"}],"ligand":{"name":"NAD(+)","id":"ChEBI:CHEBI:57540"}},{"type":"Binding site","location":{"start":{"value":342,"modifier":"EXACT"},"end":{"value":342,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:57540"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-3"}],"ligand":{"name":"NAD(+)","id":"ChEBI:CHEBI:57540"}},{"type":"Binding site","location":{"start":{"value":383,"modifier":"EXACT"},"end":{"value":383,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:57692"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-3"}],"ligand":{"name":"FAD","id":"ChEBI:CHEBI:57692"}},{"type":"Disulfide bond","location":{"start":{"value":122,"modifier":"EXACT"},"end":{"value":127,"modifier":"EXACT"}},"description":"Redox-active","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-4"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023157"}],"id":"KW-1015","category":"PTM","name":"Disulfide bond"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022827"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-3"}],"id":"KW-0274","category":"Ligand","name":"FAD"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022630"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003691"}],"id":"KW-0285","category":"Ligand","name":"Flavoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-3"}],"id":"KW-0520","category":"Ligand","name":"NAD"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022857"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU365040"}],"id":"KW-0521","category":"Ligand","name":"NADP"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR000350-3"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003691"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023284"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003691"}],"id":"KW-0676","category":"Domain","name":"Redox-active center"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-CNNV9T9KCKNV1","citationType":"submission","authors":["Zhao Y.L.","Han Y."],"title":"Cloning and expression of glutathione reductase gene in Dimocarpus longan Lour.","publicationDate":"MAR-2016","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ANO58602.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KU904637","properties":[{"key":"ProteinId","value":"ANO58602.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A1B0Z300","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005739","properties":[{"key":"GoTerm","value":"C:mitochondrion"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0050660","properties":[{"key":"GoTerm","value":"F:flavin adenine dinucleotide binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0004362","properties":[{"key":"GoTerm","value":"F:glutathione-disulfide reductase (NADPH) activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0050661","properties":[{"key":"GoTerm","value":"F:NADP binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0045454","properties":[{"key":"GoTerm","value":"P:cell redox homeostasis"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0034599","properties":[{"key":"GoTerm","value":"P:cellular response to oxidative stress"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006749","properties":[{"key":"GoTerm","value":"P:glutathione metabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"FunFam","id":"3.30.390.30:FF:000008","properties":[{"key":"EntryName","value":"Glutathione reductase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.50.50.60:FF:000051","properties":[{"key":"EntryName","value":"Glutathione reductase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.390.30","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.50.50.60","properties":[{"key":"EntryName","value":"FAD/NAD(P)-binding domain"},{"key":"MatchStatus","value":"2"}]},{"database":"InterPro","id":"IPR036188","properties":[{"key":"EntryName","value":"FAD/NAD-bd_sf"}]},{"database":"InterPro","id":"IPR023753","properties":[{"key":"EntryName","value":"FAD/NAD-binding_dom"}]},{"database":"InterPro","id":"IPR016156","properties":[{"key":"EntryName","value":"FAD/NAD-linked_Rdtase_dimer_sf"}]},{"database":"InterPro","id":"IPR006324","properties":[{"key":"EntryName","value":"GSHR"}]},{"database":"InterPro","id":"IPR046952","properties":[{"key":"EntryName","value":"GSHR/TRXR-like"}]},{"database":"InterPro","id":"IPR001100","properties":[{"key":"EntryName","value":"Pyr_nuc-diS_OxRdtase"}]},{"database":"InterPro","id":"IPR004099","properties":[{"key":"EntryName","value":"Pyr_nucl-diS_OxRdtase_dimer"}]},{"database":"InterPro","id":"IPR012999","properties":[{"key":"EntryName","value":"Pyr_OxRdtase_I_AS"}]},{"database":"NCBIfam","id":"TIGR01424","properties":[{"key":"EntryName","value":"gluta_reduc_2"},{"key":"MatchStatus","value":"1"}]},{"database":"NCBIfam","id":"NF004776","properties":[{"key":"EntryName","value":"gorA"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42737","properties":[{"key":"EntryName","value":"GLUTATHIONE REDUCTASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42737:SF9","properties":[{"key":"EntryName","value":"GLUTATHIONE REDUCTASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07992","properties":[{"key":"EntryName","value":"Pyr_redox_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02852","properties":[{"key":"EntryName","value":"Pyr_redox_dim"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF000350","properties":[{"key":"EntryName","value":"Mercury_reductase_MerA"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00368","properties":[{"key":"EntryName","value":"FADPNR"}]},{"database":"PRINTS","id":"PR00411","properties":[{"key":"EntryName","value":"PNDRDTASEI"}]},{"database":"SUPFAM","id":"SSF51905","properties":[{"key":"EntryName","value":"FAD/NAD(P)-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55424","properties":[{"key":"EntryName","value":"FAD/NAD-linked reductases, dimerisation (C-terminal) domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00076","properties":[{"key":"EntryName","value":"PYRIDINE_REDOX_1"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MATPLTTPRLTTTFYKKLPLPVPLCPHFLSLPKTLSFPSHIPRSLSHYHYHHQRRHFAVRADSDNGAERARNYDFDLFTIGAGSGGVRASRFAANFGASVAVCELPFLTISSETAGGVGGTCVLRGCVPKKLLVYASKFSHEFDESNGFGWKYETEPQHDWSTLIANKNAELKRLTGIYKNILNNAGVTLIEGRGKIVDPHTVDVDGKLYSARHILISVGGRPFIPDIPGSEYAIDSDVALDLPSKPEKIAIVGGGYIALEFAGIFNGLESEVHVFIRQKKVLRGFDEEIRDFVSEQMSLRGIEFHTEESPQAILKSGDGSLSLKTNKGTVDGFSHIMFATGRRPNTKNLGLESMGVKMNKNGAIEVDEYSRTSVPSIWAVGDVTDRINLTPVALMEGGALAKTLFQDQPTKPNYRAVPSAVFSQPPIGQVGLSEEQAIQQYGDIDVFTANFRPLKATLSGLPDRVFMKLIVCAKTNKVLGLHMCGEDAPEIVQGFAVAVKAGLTKADFDATVGIHPTAAEEFVTMRTPTRKIRQDPPSEGMTDPEVKAAAGV","length":553,"molWeight":60158,"crc64":"B39C1F3AFA3B2E03","md5":"B2BF830DA7DD4E08E1608811D39A231E"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"COFACTOR":1,"SUBUNIT":1,"SIMILARITY":1},"countByFeatureType":{"Domain":2,"Region":1,"Active site":1,"Binding site":5,"Disulfide bond":1},"uniParcId":"UPI0008042ACA"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A2H4Y9S7","uniProtkbId":"A0A2H4Y9S7_9ROSI","entryAudit":{"firstPublicDate":"2018-02-28","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2018-02-28","entryVersion":19,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AUD56298.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU369118"}],"value":"Casein kinase II subunit alpha"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU369118"}],"value":"CK II alpha"}],"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU369118"}],"value":"2.7.11.1"}]}},"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU369118"}],"value":"Casein kinases are operationally defined by their preferential utilization of acidic proteins as substrates"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU369118"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU369118"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00061236"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU369118"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":34,"modifier":"EXACT"},"end":{"value":319,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Active site","location":{"start":{"value":151,"modifier":"EXACT"},"end":{"value":151,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":63,"modifier":"EXACT"},"end":{"value":63,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-AONNQUL1C9LGL","citationType":"submission","authors":["Li S.","Xu X.","Chen X.","Chen X.","Lai Z."],"title":"Cloning of Casein Kinase 2 from the embryonic callus in longan (Dimocarpus longan Lour.).","publicationDate":"OCT-2017","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AUD56298.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MG181952","properties":[{"key":"ProteinId","value":"AUD56298.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A2H4Y9S7","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005956","properties":[{"key":"GoTerm","value":"C:protein kinase CK2 complex"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0106310","properties":[{"key":"GoTerm","value":"F:protein serine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0004674","properties":[{"key":"GoTerm","value":"F:protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0051726","properties":[{"key":"GoTerm","value":"P:regulation of cell cycle"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd14132","properties":[{"key":"EntryName","value":"STKc_CK2_alpha"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000059","properties":[{"key":"EntryName","value":"Casein kinase II subunit alpha"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000088","properties":[{"key":"EntryName","value":"Casein kinase II subunit alpha"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR045216","properties":[{"key":"EntryName","value":"CK2_alpha"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR24054","properties":[{"key":"EntryName","value":"CASEIN KINASE II SUBUNIT ALPHA"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR24054:SF58","properties":[{"key":"EntryName","value":"PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSRARIYADVNVHRPRDYWDYESLTIQWGDQDDYEVVRKVGRGKYSEVFEGINISNNEKCVIKILKPVKKKKIKREIKILQNLCGGTNIVKLLDIVRDQYSKTPSLIFENVNSTDFKVLYPRLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTDELNAYLNKYNLELDPQLEALVGRHSRKPWSRFVNADNQHLVSAEAIDFLDKLLRYDHQDRLTAREAMAHPYFYQVRSAENSRMRTQ","length":333,"molWeight":39492,"crc64":"02513BDF882FB936","md5":"7BE8ED3EC8D147BE58FE26E810BFE684"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":2,"SIMILARITY":1},"countByFeatureType":{"Domain":1,"Active site":1,"Binding site":1},"uniParcId":"UPI000CA2B839"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A411HAU9","uniProtkbId":"A0A411HAU9_9ROSI","entryAudit":{"firstPublicDate":"2019-05-08","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2019-05-08","entryVersion":27,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QBB21104.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"non-specific serine/threonine protein kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"2.7.11.1"}]}},"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047899"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004251"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004251"}],"value":"Single-pass type I membrane protein","id":"SL-9905"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009592"}],"value":"Belongs to the RLP family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00008684"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Transmembrane","location":{"start":{"value":841,"modifier":"EXACT"},"end":{"value":862,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Domain","location":{"start":{"value":922,"modifier":"EXACT"},"end":{"value":1199,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":20,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":8,"modifier":"EXACT"},"end":{"value":17,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":1049,"modifier":"EXACT"},"end":{"value":1049,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":951,"modifier":"EXACT"},"end":{"value":951,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023180"}],"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022614"}],"id":"KW-0433","category":"Domain","name":"Leucine-rich repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023121"}],"id":"KW-0446","category":"Ligand","name":"Lipid-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023170"},{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QBB21104.1"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"}],"id":"KW-0732","category":"Domain","name":"Signal"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022665"}],"id":"KW-0754","category":"Ligand","name":"Steroid-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-SBNGJV8OA1PL","citationType":"submission","authors":["Song M.J.","Chen X.G.","Lai X.Z."],"title":"Cloning of heat shock transcription factor B2b from leaves in Narcissus tazetta var. chinensis.","publicationDate":"AUG-2018","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QBB21104.1"}],"value":"Longan embryogenic calli","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QBB21104.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MH745156","properties":[{"key":"ProteinId","value":"QBB21104.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A411HAU9","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A0A411HAU9","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0004674","properties":[{"key":"GoTerm","value":"F:protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0009416","properties":[{"key":"GoTerm","value":"P:response to light stimulus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0007165","properties":[{"key":"GoTerm","value":"P:signal transduction"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"FunFam","id":"1.10.510.10:FF:000291","properties":[{"key":"EntryName","value":"Brassinosteroid LRR receptor kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.80.10.10:FF:000111","properties":[{"key":"EntryName","value":"LRR receptor-like serine/threonine-protein kinase ERECTA"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.80.10.10:FF:000095","properties":[{"key":"EntryName","value":"LRR receptor-like serine/threonine-protein kinase GSO1"},{"key":"MatchStatus","value":"2"}]},{"database":"FunFam","id":"3.30.1490.310:FF:000001","properties":[{"key":"EntryName","value":"Serine/threonine-protein kinase BRI1-like 1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000150","properties":[{"key":"EntryName","value":"serine/threonine-protein kinase BRI1-like 2"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.1490.310","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.80.10.10","properties":[{"key":"EntryName","value":"Ribonuclease Inhibitor"},{"key":"MatchStatus","value":"2"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR045381","properties":[{"key":"EntryName","value":"BRI1_island_dom"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR001611","properties":[{"key":"EntryName","value":"Leu-rich_rpt"}]},{"database":"InterPro","id":"IPR003591","properties":[{"key":"EntryName","value":"Leu-rich_rpt_typical-subtyp"}]},{"database":"InterPro","id":"IPR032675","properties":[{"key":"EntryName","value":"LRR_dom_sf"}]},{"database":"InterPro","id":"IPR013210","properties":[{"key":"EntryName","value":"LRR_N_plant-typ"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR001245","properties":[{"key":"EntryName","value":"Ser-Thr/Tyr_kinase_cat_dom"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"InterPro","id":"IPR051420","properties":[{"key":"EntryName","value":"Ser_Thr_Kinases_DiverseReg"}]},{"database":"PANTHER","id":"PTHR48005","properties":[{"key":"EntryName","value":"LEUCINE RICH REPEAT KINASE 2"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR48005:SF84","properties":[{"key":"EntryName","value":"NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF20141","properties":[{"key":"EntryName","value":"Island"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00560","properties":[{"key":"EntryName","value":"LRR_1"},{"key":"MatchStatus","value":"5"}]},{"database":"Pfam","id":"PF13516","properties":[{"key":"EntryName","value":"LRR_6"},{"key":"MatchStatus","value":"3"}]},{"database":"Pfam","id":"PF13855","properties":[{"key":"EntryName","value":"LRR_8"},{"key":"MatchStatus","value":"3"}]},{"database":"Pfam","id":"PF08263","properties":[{"key":"EntryName","value":"LRRNT_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07714","properties":[{"key":"EntryName","value":"PK_Tyr_Ser-Thr"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00369","properties":[{"key":"EntryName","value":"LRR_TYP"},{"key":"MatchStatus","value":"8"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52058","properties":[{"key":"EntryName","value":"L domain-like"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52047","properties":[{"key":"EntryName","value":"RNI-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKIEWRVSSTSTSTSSSQHHQQGGIFMGRIFGFVLLLLMIPSHARQLASSNNNEEVSNLIAFKQFSVTSDPKGYLSNWTSTSTSPCSFIGVVCSDDGHVTTLKLNNFGLVGSLHLPTLTSLPQLQHLYLQGNLFSVGDLSTSRTISCNLQTVDLSLNNISGALPGRSFLHTCDHLVSVNLSHNSISQASLHISPSLLQLDLSRNRISDSFSLNYSISSCQNLNLLNFSDNKLSGKLVAAPSSCKSLSTLDLSYNLLSGDIPPTFLADSPQSLKYLDLSHNNFSGKFSSLDFGVCNNLTVINLSQNILSGAEFHPSLSSCQLLETLNLSHNALQDKIPGNLLGNLKSLKQLSMAHNQFSGDIPPELGQACGTLQEIDLSSNKLTGELPSTFTSCTSLLSLNLGNNQLSGDFLSTVVSKLPSLVYLYVPFNNITGAVPLSLTNCTKLQVLDLSSNAFTGNIRPGLCPSALEKIVLPNNYLSGTVPSELGNCKNLRTLDLSFNNLIGEIPQAIWDLPHLSDLVIWANNLTGEIPEGICVNGGNLETLILNNNQLIGNIPKSIGSCTNMIWVSLSSNKLTGEIPAEIGKLVNLAILQLGNNTLHGEIPYELGNCRSLIWLDLNSNGLSGALPTSLADQAGLVMPGIVSGKQFAFVRNEGGTACRGAGGLVEFEGVRSERLEGFPMVHSCPSTRIYSGMTVYTFAGNGSMIYLDLSYNSLSGTIPEKFGSMNYLQVLNLGHNNLTGSIPDSFGGLKAIGVLDLSHNNFQGYIPGSLGGLSFLSDLDVSNNNLSGPIPSGGQLTTFPSSRYENNSGLCGVPLPPCGSGSHSATFHNQDKKQNVETGVVIGITFFILCILGLTLALYRVKKHQKKDEQREKYIDSLPTSGSSSWKLSSVPEPLSINVATFEKPLRKLTFAHLLEATNGFSADSLIGSGGFGEVYKAQLKDGCVVAIKKLIHVTGQGDREFMAEMETIGKIKHRNLVPLLGYCKIGEERLLVYEYMKWGSLESVLHDRAKGGATRLDWAARKKIAIGSARGLAFLHHSCIPHIIHRDMKSSNVLLDENFEARVSDFGMARLVNALDTHLSVSTLAGTPGYVPPEYYQSFRCTTKGDVYSYGVILLELLSGKRPIDPSEFGDDNNLVGWAKQLHREKRSSEILDSELMTRESGDTELHQYLRIAFECLDDRPLRRPTMIQVMAMFKELQVDTESDSLDGFSLKETVMEDL","length":1221,"molWeight":132442,"crc64":"4DBEA449923540AB","md5":"7949BABD4C9EB8EC8A8475723AD9ABF3"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":2,"SUBCELLULAR LOCATION":1,"SIMILARITY":2},"countByFeatureType":{"Transmembrane":1,"Domain":1,"Region":1,"Compositional bias":1,"Active site":1,"Binding site":1},"uniParcId":"UPI0010245E86"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A411HAV1","uniProtkbId":"A0A411HAV1_9ROSI","entryAudit":{"firstPublicDate":"2019-05-08","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2019-05-08","entryVersion":28,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QBB21102.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"non-specific serine/threonine protein kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"2.7.11.1"}]}},"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047899"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004251"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004251"}],"value":"Single-pass type I membrane protein","id":"SL-9905"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009592"}],"value":"Belongs to the RLP family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00008684"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":26,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":27,"modifier":"EXACT"},"end":{"value":1132,"modifier":"EXACT"}},"description":"non-specific serine/threonine protein kinase","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5019566234"},{"type":"Transmembrane","location":{"start":{"value":750,"modifier":"EXACT"},"end":{"value":774,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Domain","location":{"start":{"value":835,"modifier":"EXACT"},"end":{"value":1121,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Active site","location":{"start":{"value":963,"modifier":"EXACT"},"end":{"value":963,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":864,"modifier":"EXACT"},"end":{"value":864,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023180"}],"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022614"}],"id":"KW-0433","category":"Domain","name":"Leucine-rich repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023170"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-SBNGJV8OA1PL","citationType":"submission","authors":["Song M.J.","Chen X.G.","Lai X.Z."],"title":"Cloning of heat shock transcription factor B2b from leaves in Narcissus tazetta var. chinensis.","publicationDate":"AUG-2018","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QBB21102.1"}],"value":"Longan embryogenic calli","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QBB21102.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MH745154","properties":[{"key":"ProteinId","value":"QBB21102.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A411HAV1","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0004674","properties":[{"key":"GoTerm","value":"F:protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0007165","properties":[{"key":"GoTerm","value":"P:signal transduction"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd14066","properties":[{"key":"EntryName","value":"STKc_IRAK"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.80.10.10:FF:000111","properties":[{"key":"EntryName","value":"LRR receptor-like serine/threonine-protein kinase ERECTA"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.80.10.10:FF:000095","properties":[{"key":"EntryName","value":"LRR receptor-like serine/threonine-protein kinase GSO1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.80.10.10:FF:000299","properties":[{"key":"EntryName","value":"Piriformospora indica-insensitive protein 2"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000526","properties":[{"key":"EntryName","value":"serine/threonine-protein kinase BRI1-like 2"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000150","properties":[{"key":"EntryName","value":"serine/threonine-protein kinase BRI1-like 2"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.80.10.10:FF:000815","properties":[{"key":"EntryName","value":"serine/threonine-protein kinase BRI1-like 2"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.1490.310","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.80.10.10","properties":[{"key":"EntryName","value":"Ribonuclease Inhibitor"},{"key":"MatchStatus","value":"2"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR045381","properties":[{"key":"EntryName","value":"BRI1_island_dom"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR001611","properties":[{"key":"EntryName","value":"Leu-rich_rpt"}]},{"database":"InterPro","id":"IPR003591","properties":[{"key":"EntryName","value":"Leu-rich_rpt_typical-subtyp"}]},{"database":"InterPro","id":"IPR032675","properties":[{"key":"EntryName","value":"LRR_dom_sf"}]},{"database":"InterPro","id":"IPR013210","properties":[{"key":"EntryName","value":"LRR_N_plant-typ"}]},{"database":"InterPro","id":"IPR051809","properties":[{"key":"EntryName","value":"Plant_receptor-like_S/T_kinase"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR001245","properties":[{"key":"EntryName","value":"Ser-Thr/Tyr_kinase_cat_dom"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR27008:SF42","properties":[{"key":"EntryName","value":"LEUCINE-RICH REPEAT PROTEIN KINASE FAMILY PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR27008","properties":[{"key":"EntryName","value":"OS04G0122200 PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF20141","properties":[{"key":"EntryName","value":"Island"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00560","properties":[{"key":"EntryName","value":"LRR_1"},{"key":"MatchStatus","value":"8"}]},{"database":"Pfam","id":"PF13855","properties":[{"key":"EntryName","value":"LRR_8"},{"key":"MatchStatus","value":"3"}]},{"database":"Pfam","id":"PF08263","properties":[{"key":"EntryName","value":"LRRNT_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07714","properties":[{"key":"EntryName","value":"PK_Tyr_Ser-Thr"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00019","properties":[{"key":"EntryName","value":"LEURICHRPT"}]},{"database":"SMART","id":"SM00369","properties":[{"key":"EntryName","value":"LRR_TYP"},{"key":"MatchStatus","value":"9"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52058","properties":[{"key":"EntryName","value":"L domain-like"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51450","properties":[{"key":"EntryName","value":"LRR"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MESSNPHHQLFLLALVFMVYHVSVSATEQVPSIKKDAAALLKFKKMIQEDPNGVLSGWQLNRNPCTWFGITCSLGRATQLDLTGNKLVGTIFFDPLSSLDMLSVLRLSSNTFTVNSTSLLNLPYALTQLELSSAGLVGLVPDNFFSKCPNLVHVNASHNNLTGSIPESLLSGSDKLQVLDLSYNNLTGSISGLVIDQNSCNSLLHLDLSHNHIVGSIPISFSNCTNLTILNLSYNQLIGEIPTTLGELNSLHSLDLSRNHITGLIPSELGNACDSLQELKLSNNNITGAVPVTFSACSWLKLLDLSNNNISGPFPDSILEKLGSLELLLLSNNIISGTLPSSISSCKNLRVVDFSSNKLSGIIPPDICQGATSLQELRLPDNLIVGEIPGQLSHCSQLKTIDFSLNYLKGSIPAELGMLENLEQLIAWFNGLEGKIPPELGKCKQLKDLILNNNHISGEIPVELFNCSNLEWISLTSNELIGEIPPEFGLLSRLAVLQLANNSLSGEIPGELENCSSLVWLDLNSNKLTGVIPPRIGRQLGAKALSGFLFGNTLVFVRNVGNSCKGVGGLLEFAGIRPERLPQIPTLKSCDFIIMYSGAVLSRFTQYQTLEYLDLSYNELRGKIPDEIGDMIALQVLELAHNQLSGEIPSSLGKLRNLGVFDASRNRLQGQIPESFSNLSFLVQIDLSNNELTGPIPQRGQLSTLPATQYANNPGLCGVPLPECRNGNNQPPVTPGDGDKKGRKLAAATWANSIVVGVLISIASICILIVWAIAMRARRKEAEEVKMLNRLQASHAATTWKIDKEKEPLSINVATFQRQLRKLKFSQLIEATNGFSAASLIGCGGFGEVFKATLKDGSSVAIKKLIRLSCQGDREFMAEMETLGKIKHRNLVPLLGYCKIGEERLLVYEFMQFGSLEEVLHGRTKTRDQRILTWEERKKIARGAAKGLCFLHHNCIPHIIHRDMKSSNVLLDHEMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSFGVVLMELLTGKRPTDKDDFGDTNLVGWVKMKVREEKQMEVIDPELLLVTKGTDEAEAEEVKEMVRYLEITLQCVDDFPSKRPSMLQVVAMLRELMPGSGNGSSNSG","length":1132,"molWeight":123880,"crc64":"E69B71DE79911FE0","md5":"074615FB564473E7763FF9D559E5FE5A"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":2,"SUBCELLULAR LOCATION":1,"SIMILARITY":2},"countByFeatureType":{"Signal":1,"Chain":1,"Transmembrane":1,"Domain":1,"Active site":1,"Binding site":1},"uniParcId":"UPI00102452B8"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A411HAV4","uniProtkbId":"A0A411HAV4_9ROSI","entryAudit":{"firstPublicDate":"2019-05-08","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2019-05-08","entryVersion":26,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QBB21101.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"non-specific serine/threonine protein kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012513"}],"value":"2.7.11.1"}]}},"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047899"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004251"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004251"}],"value":"Single-pass type I membrane protein","id":"SL-9905"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009592"}],"value":"Belongs to the RLP family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00008684"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":27,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":28,"modifier":"EXACT"},"end":{"value":1192,"modifier":"EXACT"}},"description":"non-specific serine/threonine protein kinase","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5019309570"},{"type":"Transmembrane","location":{"start":{"value":793,"modifier":"EXACT"},"end":{"value":815,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Domain","location":{"start":{"value":880,"modifier":"EXACT"},"end":{"value":1154,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":772,"modifier":"EXACT"},"end":{"value":791,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":774,"modifier":"EXACT"},"end":{"value":783,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":1005,"modifier":"EXACT"},"end":{"value":1005,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":909,"modifier":"EXACT"},"end":{"value":909,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023180"}],"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022614"}],"id":"KW-0433","category":"Domain","name":"Leucine-rich repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023121"}],"id":"KW-0446","category":"Ligand","name":"Lipid-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023170"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022665"}],"id":"KW-0754","category":"Ligand","name":"Steroid-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-SBNGJV8OA1PL","citationType":"submission","authors":["Song M.J.","Chen X.G.","Lai X.Z."],"title":"Cloning of heat shock transcription factor B2b from leaves in Narcissus tazetta var. chinensis.","publicationDate":"AUG-2018","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QBB21101.1"}],"value":"Longan embryogenic calli","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QBB21101.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MH745153","properties":[{"key":"ProteinId","value":"QBB21101.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A411HAV4","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0004674","properties":[{"key":"GoTerm","value":"F:protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0009416","properties":[{"key":"GoTerm","value":"P:response to light stimulus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0007165","properties":[{"key":"GoTerm","value":"P:signal transduction"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd14066","properties":[{"key":"EntryName","value":"STKc_IRAK"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000291","properties":[{"key":"EntryName","value":"Brassinosteroid LRR receptor kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.80.10.10:FF:000383","properties":[{"key":"EntryName","value":"Leucine-rich repeat receptor protein kinase EMS1"},{"key":"MatchStatus","value":"2"}]},{"database":"FunFam","id":"3.80.10.10:FF:000111","properties":[{"key":"EntryName","value":"LRR receptor-like serine/threonine-protein kinase ERECTA"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.80.10.10:FF:000095","properties":[{"key":"EntryName","value":"LRR receptor-like serine/threonine-protein kinase GSO1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.1490.310:FF:000001","properties":[{"key":"EntryName","value":"Serine/threonine-protein kinase BRI1-like 1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000150","properties":[{"key":"EntryName","value":"serine/threonine-protein kinase BRI1-like 2"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.1490.310","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.80.10.10","properties":[{"key":"EntryName","value":"Ribonuclease Inhibitor"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR045381","properties":[{"key":"EntryName","value":"BRI1_island_dom"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR001611","properties":[{"key":"EntryName","value":"Leu-rich_rpt"}]},{"database":"InterPro","id":"IPR003591","properties":[{"key":"EntryName","value":"Leu-rich_rpt_typical-subtyp"}]},{"database":"InterPro","id":"IPR032675","properties":[{"key":"EntryName","value":"LRR_dom_sf"}]},{"database":"InterPro","id":"IPR013210","properties":[{"key":"EntryName","value":"LRR_N_plant-typ"}]},{"database":"InterPro","id":"IPR055414","properties":[{"key":"EntryName","value":"LRR_R13L4/SHOC2-like"}]},{"database":"InterPro","id":"IPR051716","properties":[{"key":"EntryName","value":"Plant_RL_S/T_kinase"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR001245","properties":[{"key":"EntryName","value":"Ser-Thr/Tyr_kinase_cat_dom"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR48053","properties":[{"key":"EntryName","value":"LEUCINE RICH REPEAT FAMILY PROTEIN, EXPRESSED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR48053:SF11","properties":[{"key":"EntryName","value":"PROTEIN BRASSINOSTEROID INSENSITIVE 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF20141","properties":[{"key":"EntryName","value":"Island"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00560","properties":[{"key":"EntryName","value":"LRR_1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF23598","properties":[{"key":"EntryName","value":"LRR_14"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13516","properties":[{"key":"EntryName","value":"LRR_6"},{"key":"MatchStatus","value":"2"}]},{"database":"Pfam","id":"PF13855","properties":[{"key":"EntryName","value":"LRR_8"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF08263","properties":[{"key":"EntryName","value":"LRRNT_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07714","properties":[{"key":"EntryName","value":"PK_Tyr_Ser-Thr"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00019","properties":[{"key":"EntryName","value":"LEURICHRPT"}]},{"database":"SMART","id":"SM00369","properties":[{"key":"EntryName","value":"LRR_TYP"},{"key":"MatchStatus","value":"8"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52058","properties":[{"key":"EntryName","value":"L domain-like"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52047","properties":[{"key":"EntryName","value":"RNI-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MISLFSLSSLSLFFLLSFTCLSPQAASSTTNRDAQQLMSFKAALPNPVPPLFQNWFHGQNPCDFQGVSCKATRVSSIDLSGNHLNTDFQLVSTYLLTLDSLETLSSKNTNLSGTISLPAGSRCSSVLSSLDLSLNTLSGPLSDISNLGSCTSLKYLNLSSNQLDFSGKEPGGLKLSLEVLDLSLNKISGANVVPWILYNGCDELKQLVLKQNKVTGDINVSKCKSLVHLDVSANNFSTVVPSFGDCLALEVLDISGNHFIGDIWRALSGCEQLTFLNVSRNSFSGPVPVLSAPNLQYLLLADNGFQGEIPLHLAAASCPSLVKLDLSSNNLSGMIPSSFSSCSSLESFDISSNQFSGELPIQTFLQMSSLKELALSFNFFTGGLPDSLANLTTLETLDLSSNNLSGPIPANLCQDPRNSLKQLYLQNNLLTGFIPPTLSNCSQLVSLHLSFNSLTGTIPSSLGSLSKLRDLKLWLNQLHGHIPQELGNIHTLENLILDFNELTGTIPSRLSNCTNLNWISLSNNYLSGEIPSWIGQLPSLAILKLSNNSFYGRIPPELGDCSSLIWLDLNTNYLNGSIPPALFKQSGKIAVNNIAGKRYVYIKNDGSKECHGAGNLLEFAGIRPDHLNRISTRNPCNFTRVYGGHTQPTFNNNGSMIFLDISHNLLSGSIPKEIGSMSYLYVLNLGHNNLSGAIPTEVGDLRGLNILDLSNNRLQGPIPGSMSALSLLSEVDLSSNYLSGMIPEMGQLETFPPAKFMNNSGLCGLPLPPCGRDSGSSANSQQQKSHRRPASPAGSIAMGLLFSLFCIVGLVIVAIEMRKRRKKKDSTLDIYIDSRSHSGTANTSWKLTGAREALSINLAAFEKPLRKLTFADLLEATNGFHNDSLIGSGGFGDVYKAQLKDGSIVAIKKLIHISGQGDREFTAEMETIGKIKHRNLVPLLGYCKVGEERLLVYDYMRYGSLEDVLHQKKAGIKLNWSMRRKIAIGAARGLAFLHHNCIPHIIHRDMKSSNVLLDENWEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPTDSADFGDNNLVGWVKQHAKLKISDVFDPELMKEDPNLEIELLQHLRVACACLDDRSWRRPTMIQVMAMFKEIQAGSGLDSQSTITTDDGGFSTVEMVEMSIQETPEPTRQ","length":1192,"molWeight":129893,"crc64":"B9103F219442E10B","md5":"148D5F5E3DAC58BF91A017275220752F"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":2,"SUBCELLULAR LOCATION":1,"SIMILARITY":2},"countByFeatureType":{"Signal":1,"Chain":1,"Transmembrane":1,"Domain":1,"Region":1,"Compositional bias":1,"Active site":1,"Binding site":1},"uniParcId":"UPI00102478BC"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A891LV31","uniProtkbId":"A0A891LV31_9ROSI","entryAudit":{"firstPublicDate":"2021-09-29","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"2021-09-29","entryVersion":21,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QRM13303.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00040090"}],"value":"Trans-cinnamate 4-monooxygenase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00038946"}],"value":"1.14.14.91"}]},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00041322"}],"value":"Cinnamic acid 4-hydroxylase"}},{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00042998"}],"value":"Cytochrome P450 73"}},{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00042815"}],"value":"Cytochrome P450C4H"}}]},"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00045946"}],"value":"Catalyzes the first oxidative step of the phenylpropanoid pathway in higher plants by transforming trans-cinnamate into p-coumarate. The compounds formed by this pathway are essential components for lignification, pollination, and defense against ultraviolet light, predators and pathogens"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"(E)-cinnamate + reduced [NADPH--hemoprotein reductase] + O2 = (E)-4-coumarate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:10608"},{"database":"Rhea","id":"RHEA-COMP:11964"},{"database":"Rhea","id":"RHEA-COMP:11965"},{"database":"ChEBI","id":"CHEBI:12876"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:15379"},{"database":"ChEBI","id":"CHEBI:15669"},{"database":"ChEBI","id":"CHEBI:57618"},{"database":"ChEBI","id":"CHEBI:58210"}],"ecNumber":"1.14.14.91","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048198"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"heme","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001971"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR602401-1"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:30413"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00037893"}],"value":"Phenylpropanoid metabolism; trans-4-coumarate biosynthesis; trans-4-coumarate from trans-cinnamate: step 1/1"}],"commentType":"PATHWAY"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004167"}],"value":"Membrane","id":"SL-0162"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004167"}],"value":"Single-pass membrane protein","id":"SL-9904"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00010617"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000461"}],"value":"Belongs to the cytochrome P450 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Binding site","location":{"start":{"value":447,"modifier":"EXACT"},"end":{"value":447,"modifier":"EXACT"}},"description":"axial binding residue","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30413"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR602401-1"}],"ligand":{"name":"heme","id":"ChEBI:CHEBI:30413"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022617"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR602401-1"}],"id":"KW-0349","category":"Ligand","name":"Heme"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR602401-1"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR602401-1"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023033"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000461"}],"id":"KW-0503","category":"Molecular function","name":"Monooxygenase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000461"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-8MH9S07GO4M8T","citationType":"submission","authors":["Chen Q.Y.","Li S.L.","Liu C.M.","Fu J.X."],"publicationDate":"MAR-2020","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QRM13303.1"}],"value":"Pericarp","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QRM13303.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MT185938","properties":[{"key":"ProteinId","value":"QRM13303.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A891LV31","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0020037","properties":[{"key":"GoTerm","value":"F:heme binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0005506","properties":[{"key":"GoTerm","value":"F:iron ion binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016710","properties":[{"key":"GoTerm","value":"F:trans-cinnamate 4-monooxygenase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0009808","properties":[{"key":"GoTerm","value":"P:lignin metabolic process"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd11074","properties":[{"key":"EntryName","value":"CYP73"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.630.10:FF:000013","properties":[{"key":"EntryName","value":"Trans-cinnamate 4-monooxygenase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.630.10","properties":[{"key":"EntryName","value":"Cytochrome P450"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR001128","properties":[{"key":"EntryName","value":"Cyt_P450"}]},{"database":"InterPro","id":"IPR017972","properties":[{"key":"EntryName","value":"Cyt_P450_CS"}]},{"database":"InterPro","id":"IPR002401","properties":[{"key":"EntryName","value":"Cyt_P450_E_grp-I"}]},{"database":"InterPro","id":"IPR036396","properties":[{"key":"EntryName","value":"Cyt_P450_sf"}]},{"database":"PANTHER","id":"PTHR47948","properties":[{"key":"EntryName","value":"TRANS-CINNAMATE 4-MONOOXYGENASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR47948:SF11","properties":[{"key":"EntryName","value":"TRANS-CINNAMATE 4-MONOOXYGENASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00067","properties":[{"key":"EntryName","value":"p450"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00463","properties":[{"key":"EntryName","value":"EP450I"}]},{"database":"PRINTS","id":"PR00385","properties":[{"key":"EntryName","value":"P450"}]},{"database":"SUPFAM","id":"SSF48264","properties":[{"key":"EntryName","value":"Cytochrome P450"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00086","properties":[{"key":"EntryName","value":"CYTOCHROME_P450"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDLLLLEKTLLGLFVAAIVAIVVSKLRGKKFKLPPGPLPVPVFGNWLQVGDDLNHRNLTDLAKKFGDILLLRMGQRNLVVVSSPELAKDVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRYGWEDEAAKVVEDVKKNPQAATTGIVLRKRLQMLMYNNMYRIMFDRRFESEDDPLFNRLKALNGERSRLAQSFDYNYGDFIPILRPFLRGYLKICKQVKETRLQLFKDYFVEERKKLSSTKSMNNEGLKCAIDHILDAQQKGEINEDNVLYIVENINVAAIETTLWSLEWGIAELVNHPEIQRKLRHELDTVLGRDVPVTEPDTTKLPYLQAVIKETLRLRMAIPLLVPHMNLNDAKLGGYDIPAESKILVNAWWLANNPSTWKDPQEFRPERFLEEESKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKLDTTEKGGQFSLHILKHSTIVAKPRSF","length":505,"molWeight":57914,"crc64":"5271F400D7B45BF2","md5":"2D0C30A95F92FBF649E68C123B4A7BF7"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"COFACTOR":1,"PATHWAY":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Binding site":1},"uniParcId":"UPI001AF51A5E"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A891LX26","uniProtkbId":"A0A891LX26_9ROSI","entryAudit":{"firstPublicDate":"2021-09-29","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2021-09-29","entryVersion":20,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QRM13304.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012139"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003955"}],"value":"Phenylalanine ammonia-lyase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012139"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003955"}],"value":"4.3.1.24"}]}},"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00002235"}],"value":"This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-histidine = trans-urocanate + NH4(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:21232"},{"database":"ChEBI","id":"CHEBI:17771"},{"database":"ChEBI","id":"CHEBI:28938"},{"database":"ChEBI","id":"CHEBI:57595"}],"ecNumber":"4.3.1.3","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10122"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-phenylalanine = (E)-cinnamate + NH4(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:21384"},{"database":"ChEBI","id":"CHEBI:15669"},{"database":"ChEBI","id":"CHEBI:28938"},{"database":"ChEBI","id":"CHEBI:58095"}],"ecNumber":"4.3.1.24","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023537"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003955"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00005138"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003955"}],"value":"Phenylpropanoid metabolism; trans-cinnamate biosynthesis; trans-cinnamate from L-phenylalanine: step 1/1"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00011881"}],"value":"Homotetramer"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004496"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003955"}],"value":"Cytoplasm","id":"SL-0086"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00007238"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003954"}],"value":"Belongs to the PAL/histidase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Modified residue","location":{"start":{"value":214,"modifier":"EXACT"},"end":{"value":214,"modifier":"EXACT"}},"description":"2,3-didehydroalanine (Ser)","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10122"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022490"}],"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023239"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003954"}],"id":"KW-0456","category":"Molecular function","name":"Lyase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023232"}],"id":"KW-0585","category":"Biological process","name":"Phenylalanine catabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023051"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003955"}],"id":"KW-0587","category":"Biological process","name":"Phenylpropanoid metabolism"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-8MH9S07GO4M8T","citationType":"submission","authors":["Chen Q.Y.","Li S.L.","Liu C.M.","Fu J.X."],"publicationDate":"MAR-2020","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QRM13304.1"}],"value":"Pericarp","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QRM13304.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MT185939","properties":[{"key":"ProteinId","value":"QRM13304.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A891LX26","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A0A891LX26","properties":[{"key":"Description","value":"-"}]},{"database":"UniPathway","id":"UPA00713","properties":[{"key":"RectionId","value":"UER00725"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0004397","properties":[{"key":"GoTerm","value":"F:histidine ammonia-lyase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0045548","properties":[{"key":"GoTerm","value":"F:phenylalanine ammonia-lyase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0009800","properties":[{"key":"GoTerm","value":"P:cinnamic acid biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniPathway"}]},{"database":"GO","id":"GO:0006559","properties":[{"key":"GoTerm","value":"P:L-phenylalanine catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006979","properties":[{"key":"GoTerm","value":"P:response to oxidative stress"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0009611","properties":[{"key":"GoTerm","value":"P:response to wounding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd00332","properties":[{"key":"EntryName","value":"PAL-HAL"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.275.10:FF:000009","properties":[{"key":"EntryName","value":"Phenylalanine ammonia-lyase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.20.200.10:FF:000009","properties":[{"key":"EntryName","value":"Phenylalanine ammonia-lyase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.200.10","properties":[{"key":"EntryName","value":"Fumarase/aspartase (Central domain)"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.275.10","properties":[{"key":"EntryName","value":"Fumarase/aspartase (N-terminal domain)"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.274.20","properties":[{"key":"EntryName","value":"Phenylalanine ammonia-lyase 1, domain 3"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR001106","properties":[{"key":"EntryName","value":"Aromatic_Lyase"}]},{"database":"InterPro","id":"IPR024083","properties":[{"key":"EntryName","value":"Fumarase/histidase_N"}]},{"database":"InterPro","id":"IPR008948","properties":[{"key":"EntryName","value":"L-Aspartase-like"}]},{"database":"InterPro","id":"IPR022313","properties":[{"key":"EntryName","value":"Phe/His_NH3-lyase_AS"}]},{"database":"InterPro","id":"IPR005922","properties":[{"key":"EntryName","value":"Phe_NH3-lyase"}]},{"database":"InterPro","id":"IPR023144","properties":[{"key":"EntryName","value":"Phe_NH3-lyase_shielding_dom_sf"}]},{"database":"NCBIfam","id":"TIGR01226","properties":[{"key":"EntryName","value":"phe_am_lyase"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10362","properties":[{"key":"EntryName","value":"HISTIDINE AMMONIA-LYASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00221","properties":[{"key":"EntryName","value":"Lyase_aromatic"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF48557","properties":[{"key":"EntryName","value":"L-aspartase-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00488","properties":[{"key":"EntryName","value":"PAL_HISTIDASE"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MEQVTNGTTHQNGGVRGGLLKSLCTSVNGDHHQKQDPLNWGVMAEALKVSHLEEVKRMVEEFRKPVVKLGGETLTISQVAAIAANEAGVKVELSESAREGVKASSDWVMDSMNNGTDSYGVTTGFGATSHRRTKQGAALQRELIRFLNAGVFGNGTESCHTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKLLNHNITPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKATGPNGETLDAKEASRRAGFGFFELQPKEGLALVNGTAVGSGLASMVLFEANILAVLSEVLSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSSYIKAAKKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRFSTKSIEREINSVNDNPLIDVSRNKALHGGNFQGTPIGVSMDNTRLAIASIGKLMFAQFSELVNDLYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQYLANPVTSHVQSAEQHNQDVNSLGLISSRKTAEAVDILKLMSSTFLVGLCQAIDLRHLEENLKNTVKNTVSQAAKKVLTVGANGELHPSRFCEKDLLKVVDREYVFAYVDDPCSATYPLMQKLRQVLVEHALVNGENEKNVTSSIFQKIGAFEEELKAVLPKEVENARQMYENGNAAIPNKIKECRSYPLYKFVREELGTGFLTGEKAVSPGEEFDKVFTALCQGKIIDPLLECLGEWNGAPLPIC","length":725,"molWeight":78921,"crc64":"373B967B91EDFFC7","md5":"69F4E7037327C32ACCD1F631D116CD7A"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":2,"PATHWAY":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Modified residue":1},"uniParcId":"UPI001AF27C3A"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A8G0QX21","uniProtkbId":"A0A8G0QX21_9ROSI","entryAudit":{"firstPublicDate":"2022-01-19","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2022-01-19","entryVersion":19,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07094.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07094.1"}],"value":"C-type cyclin-dependent kinase"}}]},"genes":[{"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07094.1"}],"value":"Dlo003405"}]}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048367"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047811"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:10216"},{"database":"Rhea","id":"RHEA-COMP:11321"},{"database":"Rhea","id":"RHEA-COMP:11322"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:43176"},{"database":"ChEBI","id":"CHEBI:68546"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.23","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00049280"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00065301"}],"value":"Interacts with CYCT1-3"}],"commentType":"SUBUNIT"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006485"}],"value":"Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":26,"modifier":"EXACT"},"end":{"value":325,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":336,"modifier":"EXACT"},"end":{"value":525,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":336,"modifier":"EXACT"},"end":{"value":348,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":426,"modifier":"EXACT"},"end":{"value":441,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":442,"modifier":"EXACT"},"end":{"value":455,"modifier":"EXACT"}},"description":"Gly residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":458,"modifier":"EXACT"},"end":{"value":469,"modifier":"EXACT"}},"description":"Pro residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":492,"modifier":"EXACT"},"end":{"value":501,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":516,"modifier":"EXACT"},"end":{"value":525,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":164,"modifier":"EXACT"},"end":{"value":164,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":55,"modifier":"EXACT"},"end":{"value":55,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022553"}],"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-19NA6GJ768TEM","citationType":"submission","authors":["Zhao P.","Zhang C.","Lai Z.","Lin Y."],"title":"Genome-wide identification, expression and functional analysis of core cell cycle genes (CCC) and gene families during early somatic embryogenesis in Dimocarpus longan Lour.","publicationDate":"MAY-2021","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07094.1"}],"value":"Embryonic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07094.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MZ198037","properties":[{"key":"ProteinId","value":"QYW07094.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A8G0QX21","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0000307","properties":[{"key":"GoTerm","value":"C:cyclin-dependent protein kinase holoenzyme complex"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0004693","properties":[{"key":"GoTerm","value":"F:cyclin-dependent protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0008353","properties":[{"key":"GoTerm","value":"F:RNA polymerase II CTD heptapeptide repeat kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0032968","properties":[{"key":"GoTerm","value":"P:positive regulation of transcription elongation by RNA polymerase II"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0009615","properties":[{"key":"GoTerm","value":"P:response to virus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd07840","properties":[{"key":"EntryName","value":"STKc_CDK9_like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000273","properties":[{"key":"EntryName","value":"Cyclin-dependent kinase C-2"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000272","properties":[{"key":"EntryName","value":"Cyclin-dependent kinase C-2"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050108","properties":[{"key":"EntryName","value":"CDK"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR24056","properties":[{"key":"EntryName","value":"CELL DIVISION PROTEIN KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR24056:SF560","properties":[{"key":"EntryName","value":"CYCLIN-DEPENDENT KINASE C-3"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MAIAALGQLNIGESPPAWGSRSVDCFDRLEQIGEGTYGQVFMAREIETGEIVALKKIRMDNEKEGFPITAIREIKILKKLHHENVLKLKEIVTSPGPERDEQGRPDGNKYRGSTYMVFEYMDHDLTGLADRPGQRFTVPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSFSHDHNNTLTNRVITLWYRPPELLLGATKYGSAVDMWSVGCIFAELLNGKPILPGKSEPEQLHKIFELCGSPDEIIWPGVSKLPSCNNFKPARPMKRRVREVFRHFDRHALELLEKMLMLDPSQRISAKDALDAEYFWTDPLPCDPKSLPKYESSHEFQTKKRRQQQQRQHEEATKRQKLQHTRLPPILHGGQSHHPPAHWSNQNHHMNNAPPPPVPAGPSGHHHYGKPRGPPGGPGPNRYAGGNQSSGYNPNRGGGGSGSQVGGYSNGPYPPQGRAPPPYGGSSMEANAPRGPSSGYGVVPPNYSQSGQYGTSAPGGRGPNPMAGGNRNQQYGWQQ","length":525,"molWeight":58283,"crc64":"D6B3AD1D7F6E4F99","md5":"F3BFB44970E23C3A7CA9F4A336AC459B"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":5,"SUBUNIT":1,"SIMILARITY":2},"countByFeatureType":{"Domain":1,"Region":1,"Compositional bias":6,"Active site":1,"Binding site":1},"uniParcId":"UPI001CE4E2ED"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A8G0QX24","uniProtkbId":"A0A8G0QX24_9ROSI","entryAudit":{"firstPublicDate":"2022-01-19","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2022-01-19","entryVersion":20,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07097.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012425"}],"value":"cyclin-dependent kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012425"}],"value":"2.7.11.22"}]}},"genes":[{"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07097.1"}],"value":"Dlo018928"}]}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048367"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047811"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006485"}],"value":"Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":412,"modifier":"EXACT"},"end":{"value":703,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":197,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":232,"modifier":"EXACT"},"end":{"value":401,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":734,"modifier":"EXACT"},"end":{"value":758,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":8,"modifier":"EXACT"},"end":{"value":68,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":76,"modifier":"EXACT"},"end":{"value":85,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":133,"modifier":"EXACT"},"end":{"value":143,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":156,"modifier":"EXACT"},"end":{"value":165,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":240,"modifier":"EXACT"},"end":{"value":253,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":264,"modifier":"EXACT"},"end":{"value":278,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":280,"modifier":"EXACT"},"end":{"value":289,"modifier":"EXACT"}},"description":"Acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":299,"modifier":"EXACT"},"end":{"value":312,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":317,"modifier":"EXACT"},"end":{"value":359,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":367,"modifier":"EXACT"},"end":{"value":376,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":536,"modifier":"EXACT"},"end":{"value":536,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022553"}],"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-19NA6GJ768TEM","citationType":"submission","authors":["Zhao P.","Zhang C.","Lai Z.","Lin Y."],"title":"Genome-wide identification, expression and functional analysis of core cell cycle genes (CCC) and gene families during early somatic embryogenesis in Dimocarpus longan Lour.","publicationDate":"MAY-2021","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07097.1"}],"value":"Embryonic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07097.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MZ198040","properties":[{"key":"ProteinId","value":"QYW07097.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A8G0QX24","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A0A8G0QX24","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0004693","properties":[{"key":"GoTerm","value":"F:cyclin-dependent protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0007346","properties":[{"key":"GoTerm","value":"P:regulation of mitotic cell cycle"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd07843","properties":[{"key":"EntryName","value":"STKc_CDC2L1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000211","properties":[{"key":"EntryName","value":"Cyclin-dependent kinase G-2"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000172","properties":[{"key":"EntryName","value":"cyclin-dependent kinase G-2 isoform X1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050108","properties":[{"key":"EntryName","value":"CDK"}]},{"database":"InterPro","id":"IPR045267","properties":[{"key":"EntryName","value":"CDK11/PITSLRE_STKc"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR24056","properties":[{"key":"EntryName","value":"CELL DIVISION PROTEIN KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR24056:SF107","properties":[{"key":"EntryName","value":"CYCLIN-DEPENDENT KINASE 11A-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MAAGRHGGYRENEFRDRESELDVSRREFGYSKEKYDYERIRNSNHESNGRGVRDRVRVRQKDVKEREVVVNGGGYHSSSSRSDSGSSGGGGSQEPGIREFLGSTVDREPGELSSESGSEEAIESESKVKDNEVSNVVENGVGSPLVKKRKFSPIVWDRDDNEASKSRNSPIVTALPPPPPLPKVYRKSPNVGPEGGVHITSLKIRRTQNLQSISPINPPVASRSIAYAASESPVGLDVTPPKEQRLGNDHEVEQLDDEDYAPTRNISSSRWAAGNSSPVDEGEILEDEEIPRKRKKMSLSESLQTKLRNKSISPELGELKRIGSERDRSKSSESDERDSRGRSMSGDDYHGNDSEKDDYMETEDQNNNDISVSGSDADSEGENDSHDTMQESVAPPQRSVNMLQGCRSVDEFERLNKIDEGTYGVVYRAKDKKTGEIVALKKVKMEKEREGFPLTSLREINILLSFHHPSIVDVKEVVVGSNLDSIFMVMEYMEHDLKGLMEAMKQPFSQSEVKCLMLQLLEGTKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLARQYGSPLKPYTHLVVTLWYRAPELLLGAKQYSTAIDMWSLGCIMAELLSKEPLFNGKTEFDQLDKIFRTLGTPNETIWPGFSKLPGVKVNFVKHQYNLLRKKFPATSFTGSPVLSDAGFDLLNKLLTYDPEKRITAEAALNHDWFREVPLPKSKDFMPTFPAQHAQDRRMRRIMKSPDPLEEQRRKELQQAELGTGGLFG","length":758,"molWeight":85300,"crc64":"A67D5CE8881DECE7","md5":"86BE49122C9B024082A511106EA2D47F"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":4,"SIMILARITY":2},"countByFeatureType":{"Domain":1,"Region":3,"Compositional bias":10,"Active site":1},"uniParcId":"UPI001CE6E059"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A8G0QX80","uniProtkbId":"A0A8G0QX80_9ROSI","entryAudit":{"firstPublicDate":"2022-01-19","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2022-01-19","entryVersion":20,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07095.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00067338"}],"value":"Cyclin-dependent kinase E-1"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012425"}],"value":"2.7.11.22"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012409"}],"value":"2.7.11.23"}]}},"genes":[{"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07095.1"}],"value":"Dlo032479"}]}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048367"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047811"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:10216"},{"database":"Rhea","id":"RHEA-COMP:11321"},{"database":"Rhea","id":"RHEA-COMP:11322"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:43176"},{"database":"ChEBI","id":"CHEBI:68546"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.23","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00049280"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006485"}],"value":"Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":31,"modifier":"EXACT"},"end":{"value":341,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":24,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":440,"modifier":"EXACT"},"end":{"value":484,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":22,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":446,"modifier":"EXACT"},"end":{"value":463,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":162,"modifier":"EXACT"},"end":{"value":162,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":64,"modifier":"EXACT"},"end":{"value":64,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022553"}],"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-19NA6GJ768TEM","citationType":"submission","authors":["Zhao P.","Zhang C.","Lai Z.","Lin Y."],"title":"Genome-wide identification, expression and functional analysis of core cell cycle genes (CCC) and gene families during early somatic embryogenesis in Dimocarpus longan Lour.","publicationDate":"MAY-2021","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07095.1"}],"value":"Embryonic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07095.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MZ198038","properties":[{"key":"ProteinId","value":"QYW07095.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A8G0QX80","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0016592","properties":[{"key":"GoTerm","value":"C:mediator complex"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0004693","properties":[{"key":"GoTerm","value":"F:cyclin-dependent protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0008353","properties":[{"key":"GoTerm","value":"F:RNA polymerase II CTD heptapeptide repeat kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"CDD","id":"cd07842","properties":[{"key":"EntryName","value":"STKc_CDK8_like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000350","properties":[{"key":"EntryName","value":"Cyclin-dependent kinase e-1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000374","properties":[{"key":"EntryName","value":"Putative cyclin-dependent kinase E-1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050108","properties":[{"key":"EntryName","value":"CDK"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR24056","properties":[{"key":"EntryName","value":"CELL DIVISION PROTEIN KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR24056:SF495","properties":[{"key":"EntryName","value":"CYCLIN-DEPENDENT KINASE 8-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MGDGNNTNRGVTTSTGSSNNNSEKPEWLQQYNLIGKIGEGTYGLVFLARTKSPANRGKSIAIKKFKQSKDGDGVSPTAIREIMLLREITHENVVKLVNVHINHADMSLYLAFDYAEYDLYEIIRHHRDKVNQIINLYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDGEEQGVVKIADFGLARIYQAPLKFLSENGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGAEAKSTQNPFQFDQLDKIFKILGHPTPEKWPTLASLPHWSSDSQHIQGRKYETNGLPSVVHLNPKSPAYDLLSKMLEYDPRKRITAAQALEHEYFRIEPLPGRNALVPSQTGPGEKVVTYPTRPVDANTDFEGTTTLQPPQPAASGNPVAGSMAGAHAMSNRNVPRPMPAAVGMQRMQPQGMMAYNFPSQAGAAGGMNPGGMPMQRGMAAQAHQQQQLRRKDPGMMPGYPPQQKSRRL","length":484,"molWeight":53756,"crc64":"C3CB13DCE957BD45","md5":"C0C335675FFFF1ABABE98B69DB81E158"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":5,"SIMILARITY":2},"countByFeatureType":{"Domain":1,"Region":2,"Compositional bias":2,"Active site":1,"Binding site":1},"uniParcId":"UPI001CE6CF1D"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A8G0QXX1","uniProtkbId":"A0A8G0QXX1_9ROSI","entryAudit":{"firstPublicDate":"2022-01-19","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2022-01-19","entryVersion":17,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07101.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07101.1"}],"value":"D-type cyclin dependence kinase"}}]},"genes":[{"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07101.1"}],"value":"Dlo031379"}]}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048367"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047811"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:10216"},{"database":"Rhea","id":"RHEA-COMP:11321"},{"database":"Rhea","id":"RHEA-COMP:11322"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:43176"},{"database":"ChEBI","id":"CHEBI:68546"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.23","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00049280"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006485"}],"value":"Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":14,"modifier":"EXACT"},"end":{"value":294,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":296,"modifier":"EXACT"},"end":{"value":368,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":314,"modifier":"EXACT"},"end":{"value":323,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":339,"modifier":"EXACT"},"end":{"value":368,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":136,"modifier":"EXACT"},"end":{"value":136,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR637770-1"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":20,"modifier":"EXACT"},"end":{"value":28,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR637770-2"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}},{"type":"Binding site","location":{"start":{"value":43,"modifier":"EXACT"},"end":{"value":43,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR637770-2"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}},{"type":"Binding site","location":{"start":{"value":44,"modifier":"EXACT"},"end":{"value":44,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR637770-2"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR637770-2"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022553"}],"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-19NA6GJ768TEM","citationType":"submission","authors":["Zhao P.","Zhang C.","Lai Z.","Lin Y."],"title":"Genome-wide identification, expression and functional analysis of core cell cycle genes (CCC) and gene families during early somatic embryogenesis in Dimocarpus longan Lour.","publicationDate":"MAY-2021","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07101.1"}],"value":"Embryonic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07101.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MZ198044","properties":[{"key":"ProteinId","value":"QYW07101.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A8G0QXX1","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0070985","properties":[{"key":"GoTerm","value":"C:transcription factor TFIIK complex"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0004693","properties":[{"key":"GoTerm","value":"F:cyclin-dependent protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0008353","properties":[{"key":"GoTerm","value":"F:RNA polymerase II CTD heptapeptide repeat kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0045944","properties":[{"key":"GoTerm","value":"P:positive regulation of transcription by RNA polymerase II"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd07841","properties":[{"key":"EntryName","value":"STKc_CDK7"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000289","properties":[{"key":"EntryName","value":"Cyclin-dependent kinase D-1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000097","properties":[{"key":"EntryName","value":"Putative cyclin-dependent kinase 7"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050108","properties":[{"key":"EntryName","value":"CDK"}]},{"database":"InterPro","id":"IPR037770","properties":[{"key":"EntryName","value":"CDK7"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR24056","properties":[{"key":"EntryName","value":"CELL DIVISION PROTEIN KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR24056:SF554","properties":[{"key":"EntryName","value":"CYCLIN-DEPENDENT KINASE D-1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MTQIDLSKKVADRYLKREVLGEGTYGVVYKAIDTKTGQTVAIKKIRLGKQKEGVNFTALREIKLLKELKDPNIIELIDAFPHKGNLHLVFEFMETDLETVIRNTNIFLSPADIKSYMQMTLKGLAFCHKKWVLHRDMKPNNLLIGSHGQLKLADFGLARIFGSPDRKFTHQVFARWYRAPELLFGAKQYGAGVDVWAAGCIFAELLNRRPFLQGTSDMDQLGKIFAALGTATPAQWPDLAYLPDYVEYQYVTPPPFRSLFPTASDDALDLLLKMLTYDPKARITAQQALEHRYFSSAPLPTEPNKLPRPAPKQRVSEASDVKPQEGPTVLSPPRKSRRVMPEREGFGANAHRVDKIEDHAGERKQTGW","length":368,"molWeight":41634,"crc64":"CAD2ECD1EB26235C","md5":"CB5B837E6749B13BD96FE133CD24FE59"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":5,"SIMILARITY":2},"countByFeatureType":{"Domain":1,"Region":1,"Compositional bias":2,"Active site":1,"Binding site":3},"uniParcId":"UPI001CE68B45"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A8G0QXX4","uniProtkbId":"A0A8G0QXX4_9ROSI","entryAudit":{"firstPublicDate":"2022-01-19","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2022-01-19","entryVersion":17,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07093.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07093.1"}],"value":"B-type cyclin-dependent kinase 2"}}]},"genes":[{"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07093.1"}],"value":"Dlo013170"}]}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048367"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047811"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:10216"},{"database":"Rhea","id":"RHEA-COMP:11321"},{"database":"Rhea","id":"RHEA-COMP:11322"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:43176"},{"database":"ChEBI","id":"CHEBI:68546"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.23","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00049280"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006485"}],"value":"Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":6,"modifier":"EXACT"},"end":{"value":296,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Active site","location":{"start":{"value":137,"modifier":"EXACT"},"end":{"value":137,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":35,"modifier":"EXACT"},"end":{"value":35,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022553"}],"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-19NA6GJ768TEM","citationType":"submission","authors":["Zhao P.","Zhang C.","Lai Z.","Lin Y."],"title":"Genome-wide identification, expression and functional analysis of core cell cycle genes (CCC) and gene families during early somatic embryogenesis in Dimocarpus longan Lour.","publicationDate":"MAY-2021","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07093.1"}],"value":"Embryonic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07093.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MZ198036","properties":[{"key":"ProteinId","value":"QYW07093.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A8G0QXX4","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0000307","properties":[{"key":"GoTerm","value":"C:cyclin-dependent protein kinase holoenzyme complex"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0030332","properties":[{"key":"GoTerm","value":"F:cyclin binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0004693","properties":[{"key":"GoTerm","value":"F:cyclin-dependent protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0008353","properties":[{"key":"GoTerm","value":"F:RNA polymerase II CTD heptapeptide repeat kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0000082","properties":[{"key":"GoTerm","value":"P:G1/S transition of mitotic cell cycle"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0010389","properties":[{"key":"GoTerm","value":"P:regulation of G2/M transition of mitotic cell cycle"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0007165","properties":[{"key":"GoTerm","value":"P:signal transduction"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"FunFam","id":"1.10.510.10:FF:000281","properties":[{"key":"EntryName","value":"Cyclin-dependent kinase 2"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000231","properties":[{"key":"EntryName","value":"Cyclin-dependent kinase B2,2"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050108","properties":[{"key":"EntryName","value":"CDK"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR24056","properties":[{"key":"EntryName","value":"CELL DIVISION PROTEIN KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR24056:SF178","properties":[{"key":"EntryName","value":"CYCLIN-DEPENDENT KINASE B2-2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MLMDLFEKLEKVGEGTYGKVYRAREKATGKIVALKKTRLHEDEEGVPPTTLREVSILRMLSRDPHVVRLMDVKQGQNKEGRTVLYLVFEYMDTDLKKFIRSFRQSGENISAKTVKSLMYQLCKGIAFCHGHGILHRDLKPHNLLMDRKTQMLKIADLGLARAFTLPIKKYTHEILTLWYRAPEVLLGCTHYSTAVDMWSVGCIFAELVTKQALFPGDSELQQLLHIFRLLGTPNDQVWPGVSSLMNWHEYPQWKPLSLSTAVPNLDKDGLDLLAQMLQYEPAKRISAKKAMEHPYFDDLNKTYL","length":304,"molWeight":34965,"crc64":"1964E9E3452B13B0","md5":"A17DEA4354E427ADE9D602ED31362973"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":5,"SIMILARITY":2},"countByFeatureType":{"Domain":1,"Active site":1,"Binding site":1},"uniParcId":"UPI001CE4C7E0"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A8G0QXZ1","uniProtkbId":"A0A8G0QXZ1_9ROSI","entryAudit":{"firstPublicDate":"2022-01-19","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2022-01-19","entryVersion":20,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07098.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012425"}],"value":"cyclin-dependent kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012425"}],"value":"2.7.11.22"}]}},"genes":[{"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07098.1"}],"value":"Dlo031893"}]}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048367"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047811"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006485"}],"value":"Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":312,"modifier":"EXACT"},"end":{"value":610,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Region","location":{"start":{"value":217,"modifier":"EXACT"},"end":{"value":257,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":238,"modifier":"EXACT"},"end":{"value":248,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":443,"modifier":"EXACT"},"end":{"value":443,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022553"}],"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-19NA6GJ768TEM","citationType":"submission","authors":["Zhao P.","Zhang C.","Lai Z.","Lin Y."],"title":"Genome-wide identification, expression and functional analysis of core cell cycle genes (CCC) and gene families during early somatic embryogenesis in Dimocarpus longan Lour.","publicationDate":"MAY-2021","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07098.1"}],"value":"Embryonic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07098.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MZ198041","properties":[{"key":"ProteinId","value":"QYW07098.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A8G0QXZ1","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0004693","properties":[{"key":"GoTerm","value":"F:cyclin-dependent protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0007346","properties":[{"key":"GoTerm","value":"P:regulation of mitotic cell cycle"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd07843","properties":[{"key":"EntryName","value":"STKc_CDC2L1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000211","properties":[{"key":"EntryName","value":"Cyclin-dependent kinase G-2"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000172","properties":[{"key":"EntryName","value":"cyclin-dependent kinase G-2 isoform X1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050108","properties":[{"key":"EntryName","value":"CDK"}]},{"database":"InterPro","id":"IPR045267","properties":[{"key":"EntryName","value":"CDK11/PITSLRE_STKc"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR24056","properties":[{"key":"EntryName","value":"CELL DIVISION PROTEIN KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR24056:SF415","properties":[{"key":"EntryName","value":"CYCLIN-DEPENDENT KINASE G1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MAAGRVDVPRRREYSAYGYFKKEGEVVHYKNGIRDAKLSRVGRGCQNTNGCQFLSDGQKFGSRRSEAGFDDAPCVENGGVSKSEDEVQLPPEKKRKFSPIIWDLEEKEVRISSKNRIIPTSSFTYSKFADGSAREVSAVDSDGGAAKDSVLENQVEGLENKSEKPVVGCGFVGTTFPISPVGLSASLPHETAVDGLDQAHLEEELVQSHSILASRWAYDSDTQRDASPSGDDDDTSERGQSLKSSTPESGEFCRESSEDSARSNVVCSSKDEYIGSESEDDVMDIDKSPDEVAVPERRSKSMLNCCRCLSEFERLNKISEGTYGIVHRARDKMTGEIVALKEVKMNVGSSAEHSEYGFPLSSLREINILLSFNHPSIVNVKEVVMHDNNLNKVFMVMEYMEHDLKGLMESMKQPFSTSEVKCLMLQLLEGVKYLHDNWVFHRDLKTSNLLLNNQGELKICDFGMSRQYGNPLKSYTTLVVTLWYRAPELLLGMKKYSTAVDMWSVGCIMAELLAKKPLFDGKREVEQIDKIFKTLGTPTETIWPGFSELPGAKANFVKQPYNLLRKRFPATSFTGSPVLSESGYDLLNKLLTYDPDKRITADDALNHDWFHEVPLPKSKEFMPTFPPQHARNR","length":633,"molWeight":70889,"crc64":"64E2203DA2B92A7F","md5":"5B2E6B27CDC0B94150D8E8A62C4DE050"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":4,"SIMILARITY":2},"countByFeatureType":{"Domain":1,"Region":1,"Compositional bias":1,"Active site":1},"uniParcId":"UPI001CE4C380"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A8G0VTW1","uniProtkbId":"A0A8G0VTW1_9ROSI","entryAudit":{"firstPublicDate":"2022-01-19","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2022-01-19","entryVersion":19,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Dimocarpus longan","taxonId":128017,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07091.1"}],"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Sapindales","Sapindaceae","Dimocarpus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012425"}],"value":"cyclin-dependent kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012425"}],"value":"2.7.11.22"}]}},"genes":[{"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07091.1"}],"value":"Dlo004413"}]}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:17989"},{"database":"Rhea","id":"RHEA-COMP:9863"},{"database":"Rhea","id":"RHEA-COMP:11604"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29999"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:83421"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048367"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.1","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:46608"},{"database":"Rhea","id":"RHEA-COMP:11060"},{"database":"Rhea","id":"RHEA-COMP:11605"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30013"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:61977"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.11.22","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00047811"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006485"}],"value":"Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"value":"Belongs to the protein kinase superfamily. Ser/Thr protein kinase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":4,"modifier":"EXACT"},"end":{"value":287,"modifier":"EXACT"}},"description":"Protein kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50011"}]},{"type":"Active site","location":{"start":{"value":127,"modifier":"EXACT"},"end":{"value":127,"modifier":"EXACT"}},"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10027"}]},{"type":"Binding site","location":{"start":{"value":33,"modifier":"EXACT"},"end":{"value":33,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023306"}],"id":"KW-0131","category":"Biological process","name":"Cell cycle"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022618"}],"id":"KW-0132","category":"Biological process","name":"Cell division"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022776"}],"id":"KW-0498","category":"Biological process","name":"Mitosis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU10141"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022553"}],"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022527"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0723","category":"Molecular function","name":"Serine/threonine-protein kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00159"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-19NA6GJ768TEM","citationType":"submission","authors":["Zhao P.","Zhang C.","Lai Z.","Lin Y."],"title":"Genome-wide identification, expression and functional analysis of core cell cycle genes (CCC) and gene families during early somatic embryogenesis in Dimocarpus longan Lour.","publicationDate":"MAY-2021","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07091.1"}],"value":"Embryonic callus","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"QYW07091.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"MZ198034","properties":[{"key":"ProteinId","value":"QYW07091.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A8G0VTW1","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0000307","properties":[{"key":"GoTerm","value":"C:cyclin-dependent protein kinase holoenzyme complex"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0030332","properties":[{"key":"GoTerm","value":"F:cyclin binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0004693","properties":[{"key":"GoTerm","value":"F:cyclin-dependent protein serine/threonine kinase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0000082","properties":[{"key":"GoTerm","value":"P:G1/S transition of mitotic cell cycle"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0010389","properties":[{"key":"GoTerm","value":"P:regulation of G2/M transition of mitotic cell cycle"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0010468","properties":[{"key":"GoTerm","value":"P:regulation of gene expression"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0051445","properties":[{"key":"GoTerm","value":"P:regulation of meiotic cell cycle"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0007165","properties":[{"key":"GoTerm","value":"P:signal transduction"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd07835","properties":[{"key":"EntryName","value":"STKc_CDK1_CdkB_like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000187","properties":[{"key":"EntryName","value":"Cell division control protein 2"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.510.10:FF:000280","properties":[{"key":"EntryName","value":"Cell division control protein 2 homolog"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.510.10","properties":[{"key":"EntryName","value":"Transferase(Phosphotransferase) domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050108","properties":[{"key":"EntryName","value":"CDK"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"InterPro","id":"IPR000719","properties":[{"key":"EntryName","value":"Prot_kinase_dom"}]},{"database":"InterPro","id":"IPR017441","properties":[{"key":"EntryName","value":"Protein_kinase_ATP_BS"}]},{"database":"InterPro","id":"IPR008271","properties":[{"key":"EntryName","value":"Ser/Thr_kinase_AS"}]},{"database":"PANTHER","id":"PTHR24056","properties":[{"key":"EntryName","value":"CELL DIVISION PROTEIN KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR24056:SF548","properties":[{"key":"EntryName","value":"CYCLIN-DEPENDENT KINASE A-1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00069","properties":[{"key":"EntryName","value":"Pkinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00220","properties":[{"key":"EntryName","value":"S_TKc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00107","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ATP"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50011","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_DOM"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00108","properties":[{"key":"EntryName","value":"PROTEIN_KINASE_ST"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MCQYEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHGNIVRLQDVVHSERRLYLVFEYLDLDLKKHMDSCPDFAKDPRLVKTFLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEMVNQRPLFPGDSEIDELFKIFRVLGTPNEDTWPGVTSLPDFKNAFPKWPSKDLASVVPNLDPAGIDLLCKMLCMDPSRRITARSALEHEYFKDIGFVP","length":294,"molWeight":33832,"crc64":"F62B34699B053FB2","md5":"48A45DD7703463679D17338E79CC35E1"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":4,"SIMILARITY":2},"countByFeatureType":{"Domain":1,"Active site":1,"Binding site":1},"uniParcId":"UPI001CE5A909"}}]}