{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD63","uniProtkbId":"B2DD63_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2008-06-10","entryVersion":65,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28252.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00073645"}],"value":"Glutamate/aspartate import permease protein GltK"}}},"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00060298"}],"value":"Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for the translocation of the substrate across the membrane"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00062718"}],"value":"The complex is composed of two ATP-binding proteins (GltL), two transmembrane proteins (GltJ and GltK) and a solute-binding protein (GltI)"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004429"}],"value":"Cell inner membrane","id":"SL-0037"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004429"}],"value":"Multi-pass membrane protein","id":"SL-9909"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363032"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363032"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00096305"}],"value":"Belongs to the binding protein-dependent transport system permease family. HisMQ subfamily"}],"commentType":"SIMILARITY"}],"features":[{"type":"Transmembrane","location":{"start":{"value":20,"modifier":"EXACT"},"end":{"value":42,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00441"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363032"}]},{"type":"Transmembrane","location":{"start":{"value":54,"modifier":"EXACT"},"end":{"value":77,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00441"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363032"}]},{"type":"Transmembrane","location":{"start":{"value":89,"modifier":"EXACT"},"end":{"value":112,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00441"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363032"}]},{"type":"Transmembrane","location":{"start":{"value":189,"modifier":"EXACT"},"end":{"value":211,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00441"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363032"}]},{"type":"Domain","location":{"start":{"value":19,"modifier":"EXACT"},"end":{"value":208,"modifier":"EXACT"}},"description":"ABC transmembrane type-1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50928"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022970"}],"id":"KW-0029","category":"Biological process","name":"Amino-acid transport"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00441"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00441"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00441"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022448"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU363032"}],"id":"KW-0813","category":"Biological process","name":"Transport"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28252.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28252.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28252.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD63","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0043190","properties":[{"key":"GoTerm","value":"C:ATP-binding cassette (ABC) transporter complex"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0022857","properties":[{"key":"GoTerm","value":"F:transmembrane transporter activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006865","properties":[{"key":"GoTerm","value":"P:amino acid transport"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd06261","properties":[{"key":"EntryName","value":"TM_PBP2"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.3720.10:FF:000006","properties":[{"key":"EntryName","value":"Glutamate/aspartate ABC transporter, permease protein GltK"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.3720.10","properties":[{"key":"EntryName","value":"MetI-like"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR010065","properties":[{"key":"EntryName","value":"AA_ABC_transptr_permease_3TM"}]},{"database":"InterPro","id":"IPR043429","properties":[{"key":"EntryName","value":"ArtM/GltK/GlnP/TcyL/YhdX-like"}]},{"database":"InterPro","id":"IPR000515","properties":[{"key":"EntryName","value":"MetI-like"}]},{"database":"InterPro","id":"IPR035906","properties":[{"key":"EntryName","value":"MetI-like_sf"}]},{"database":"NCBIfam","id":"TIGR01726","properties":[{"key":"EntryName","value":"HEQRo_perm_3TM"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30614:SF0","properties":[{"key":"EntryName","value":"L-CYSTINE TRANSPORT SYSTEM PERMEASE PROTEIN TCYL"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30614","properties":[{"key":"EntryName","value":"MEMBRANE COMPONENT OF AMINO ACID ABC TRANSPORTER"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00528","properties":[{"key":"EntryName","value":"BPD_transp_1"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF161098","properties":[{"key":"EntryName","value":"MetI-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50928","properties":[{"key":"EntryName","value":"ABC_TM1"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MPLDFSFLIPYVPQLATAARITLTIGVFSFVLALAVSVLVGVLRSGRLPWIVDFLLGVYVEIFRNTPLLIQLFFIYYGLPTFGIVLPPVTAAVIGLSLNSGAYMSEAVRAAISSVNKGQYEAAFSLGYNRYQVFLHIVLPQAFRIALPTLMNYFTTMIKETSLVSVLSIAELTRVGNQIYARTLGPFEIYITIGAVYFVMTYSVALVSRWVEKKGIKWIP","length":220,"molWeight":24435,"crc64":"D2722CACB5D99185","md5":"FEB39163DE5B3566C4136A3942D9471B"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Transmembrane":4,"Domain":1},"uniParcId":"UPI000172D7F8"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD76","uniProtkbId":"B2DD76_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-06-10","entryVersion":51,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28265.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28265.1"}],"value":"TonB-dependent receptor"}}]},"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004571"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"value":"Cell outer membrane","id":"SL-0040"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004571"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003357"}],"value":"Belongs to the TonB-dependent receptor family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00153"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":28,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":29,"modifier":"EXACT"},"end":{"value":695,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5002777505"},{"type":"Domain","location":{"start":{"value":388,"modifier":"EXACT"},"end":{"value":415,"modifier":"EXACT"}},"description":"PLD phosphodiesterase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50035"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023237"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0998","category":"Cellular component","name":"Cell outer membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023170"},{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28265.1"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023077"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003357"}],"id":"KW-0798","category":"Domain","name":"TonB box"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022452"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-1134","category":"Domain","name":"Transmembrane beta strand"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022448"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0813","category":"Biological process","name":"Transport"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28265.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28265.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28265.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD76","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0009279","properties":[{"key":"GoTerm","value":"C:cell outer membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0003824","properties":[{"key":"GoTerm","value":"F:catalytic activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0015344","properties":[{"key":"GoTerm","value":"F:siderophore uptake transmembrane transporter activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006793","properties":[{"key":"GoTerm","value":"P:phosphorus metabolic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0044718","properties":[{"key":"GoTerm","value":"P:siderophore transmembrane transport"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd01347","properties":[{"key":"EntryName","value":"ligand_gated_channel"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.40.170.20","properties":[{"key":"EntryName","value":"TonB-dependent receptor, beta-barrel domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.170.130.10","properties":[{"key":"EntryName","value":"TonB-dependent receptor, plug domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR000531","properties":[{"key":"EntryName","value":"Beta-barrel_TonB"}]},{"database":"InterPro","id":"IPR036942","properties":[{"key":"EntryName","value":"Beta-barrel_TonB_sf"}]},{"database":"InterPro","id":"IPR001736","properties":[{"key":"EntryName","value":"PLipase_D/transphosphatidylase"}]},{"database":"InterPro","id":"IPR012910","properties":[{"key":"EntryName","value":"Plug_dom"}]},{"database":"InterPro","id":"IPR037066","properties":[{"key":"EntryName","value":"Plug_dom_sf"}]},{"database":"InterPro","id":"IPR039426","properties":[{"key":"EntryName","value":"TonB-dep_rcpt-like"}]},{"database":"PANTHER","id":"PTHR30069:SF29","properties":[{"key":"EntryName","value":"HEMOGLOBIN AND HEMOGLOBIN-HAPTOGLOBIN-BINDING PROTEIN 1-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30069","properties":[{"key":"EntryName","value":"TONB-DEPENDENT OUTER MEMBRANE RECEPTOR"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07715","properties":[{"key":"EntryName","value":"Plug"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00593","properties":[{"key":"EntryName","value":"TonB_dep_Rec_b-barrel"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56935","properties":[{"key":"EntryName","value":"Porins"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50035","properties":[{"key":"EntryName","value":"PLD"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS52016","properties":[{"key":"EntryName","value":"TONB_DEPENDENT_REC_3"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MNKLMKIMATALVFCVWTAGLMICQASGQDTENTRHHGNTAIHLDDMVVTATRFPTDKNRVPGRITVITAADIENTPFERVDELLQQVSGLQTTRTDGIFELSPQVTMRGLGGNEPGRTLVLIDGTPASTGDSGNMRWNRLNLADIERIEVFKGPGSSIYGSNAMGGVINIITKRPDKPFSGAVSAGYGSFGTKKGAVRLGGRQDGDRGFYGQVAATGLDSDGYTSLTKTSSDYDNRIDRFVEEFNVSAKLGYAFDENSSLELGYAYFDDRRGEGYKYNIPEGSHRDFDTNRMNLLYKKAVNDWQWHFSGFFQREDYFWHRDFADAASIYKVLSDRDDYGTALSVSTDIGDHSTLILGADLRISEVDAADDYDFSSDYAINKGRLEQYAFYLHDEIRFLDDRLVLVGGVRFDTAKFKDGLYDSNVAPFDLVSGSLKDSSWDAFSPKISSRYHVSDNISVYGSYSRGFRAPILDALCRYGIFHGRFYDANPDLENETLDSFELGSDLKLFDMLDLSFSGYYSRGKDFIYSVDTGQTRFLWGRNRAVYLMNNVTEVEIKGFEADLAFRPNTHIRFFAGYTFNESLIDKFDERPELEGKRLEYVPEHSFSAGVDVFSSIINARVVLNHIGNQYSDDMNTEEIGGYETVDVKLWRNLDFLLPGLSASLAVQNLFDETYLRSEDEKSPGMFTVGEIKYEW","length":695,"molWeight":78199,"crc64":"DC5B9B74F4E105CD","md5":"040742533567F810B6D93483F9CD7CFE"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SIMILARITY":1,"CAUTION":1},"countByFeatureType":{"Signal":1,"Chain":1,"Domain":1},"uniParcId":"UPI000172D805"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD88","uniProtkbId":"B2DD88_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2008-06-10","entryVersion":41,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28277.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022362"}],"value":"Protein TonB"}}},"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00025849"}],"value":"Homodimer. Forms a complex with the accessory proteins ExbB and ExbD"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004383"}],"value":"Cell inner membrane","id":"SL-0037"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004383"}],"value":"Single-pass membrane protein","id":"SL-9904"},"orientation":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004383"}],"value":"Periplasmic side","id":"SL-9916"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00006555"}],"value":"Belongs to the TonB family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":21,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":22,"modifier":"EXACT"},"end":{"value":211,"modifier":"EXACT"}},"description":"Protein TonB","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5052709453"},{"type":"Domain","location":{"start":{"value":121,"modifier":"EXACT"},"end":{"value":211,"modifier":"EXACT"}},"description":"TonB C-terminal","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS52015"}]},{"type":"Region","location":{"start":{"value":38,"modifier":"EXACT"},"end":{"value":90,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":41,"modifier":"EXACT"},"end":{"value":59,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022519"}],"id":"KW-0997","category":"Cellular component","name":"Cell inner membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022927"}],"id":"KW-0653","category":"Biological process","name":"Protein transport"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022737"}],"id":"KW-0677","category":"Domain","name":"Repeat"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022448"}],"id":"KW-0813","category":"Biological process","name":"Transport"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28277.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28277.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28277.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD88","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0030288","properties":[{"key":"GoTerm","value":"C:outer membrane-bounded periplasmic space"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0098797","properties":[{"key":"GoTerm","value":"C:plasma membrane protein complex"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0031992","properties":[{"key":"GoTerm","value":"F:energy transducer activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0015891","properties":[{"key":"GoTerm","value":"P:siderophore transport"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0055085","properties":[{"key":"GoTerm","value":"P:transmembrane transport"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.30.1150.10","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003538","properties":[{"key":"EntryName","value":"TonB"}]},{"database":"InterPro","id":"IPR051045","properties":[{"key":"EntryName","value":"TonB-dependent_transducer"}]},{"database":"InterPro","id":"IPR006260","properties":[{"key":"EntryName","value":"TonB/TolA_C"}]},{"database":"InterPro","id":"IPR037682","properties":[{"key":"EntryName","value":"TonB_C"}]},{"database":"NCBIfam","id":"TIGR01352","properties":[{"key":"EntryName","value":"tonB_Cterm"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33446:SF8","properties":[{"key":"EntryName","value":"PROTEIN TONB"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33446","properties":[{"key":"EntryName","value":"PROTEIN TONB-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03544","properties":[{"key":"EntryName","value":"TonB_C"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR01374","properties":[{"key":"EntryName","value":"TONBPROTEIN"}]},{"database":"SUPFAM","id":"SSF74653","properties":[{"key":"EntryName","value":"TolA/TonB C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS52015","properties":[{"key":"EntryName","value":"TONB_CTD"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MVLSAALNLFLFAVMPEMIRAVPENLEKHEPVQAIQVVRVKRPEPPPEKQKSPEPEPPKPQKTAAPKPVQKKMPRPPAPKPSLPFALNPKLPPMAHSLEMPPLETFSVDAPQLKDRYLAHELDAGLIPLAKVAPVYPLHATRRGIEGKVRVQFLVTADGRVADIKILAAEPEKVFDQSVIDCVSRWRFQPGRVQGIPVAALAQTTIKFQLE","length":211,"molWeight":23388,"crc64":"ECE71C22949C2F9C","md5":"3E57E16E93346DAD73DC445FF10042DF"},"extraAttributes":{"countByCommentType":{"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Signal":1,"Chain":1,"Domain":1,"Region":1,"Compositional bias":1},"uniParcId":"UPI000172D811"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD90","uniProtkbId":"B2DD90_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-06-10","entryVersion":68,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28279.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"value":"Demethylmenaquinone methyltransferase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"value":"2.1.1.163"}]}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"value":"menG"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"value":"Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + S-adenosyl-L-homocysteine + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:42640"},{"database":"Rhea","id":"RHEA-COMP:9539"},{"database":"Rhea","id":"RHEA-COMP:9563"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:18151"},{"database":"ChEBI","id":"CHEBI:55437"},{"database":"ChEBI","id":"CHEBI:57856"},{"database":"ChEBI","id":"CHEBI:59789"}],"ecNumber":"2.1.1.163","evidences":[{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"value":"Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"value":"Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Binding site","location":{"start":{"value":90,"modifier":"EXACT"},"end":{"value":90,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:59789"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"ligand":{"name":"S-adenosyl-L-methionine","id":"ChEBI:CHEBI:59789"}},{"type":"Binding site","location":{"start":{"value":118,"modifier":"EXACT"},"end":{"value":119,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:59789"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"ligand":{"name":"S-adenosyl-L-methionine","id":"ChEBI:CHEBI:59789"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022428"},{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"id":"KW-0474","category":"Biological process","name":"Menaquinone biosynthesis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022603"},{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"id":"KW-0489","category":"Molecular function","name":"Methyltransferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022691"},{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"id":"KW-0949","category":"Ligand","name":"S-adenosyl-L-methionine"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"HAMAP-Rule","id":"MF_01813"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28279.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28279.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28279.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD90","properties":[{"key":"Description","value":"-"}]},{"database":"UniPathway","id":"UPA00079","properties":[{"key":"RectionId","value":"UER00169"}]},{"database":"UniPathway","id":"UPA00232","properties":[{"key":"RectionId","value":"-"}]},{"database":"GO","id":"GO:0008425","properties":[{"key":"GoTerm","value":"F:2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0043770","properties":[{"key":"GoTerm","value":"F:demethylmenaquinone methyltransferase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0009234","properties":[{"key":"GoTerm","value":"P:menaquinone biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"CDD","id":"cd02440","properties":[{"key":"EntryName","value":"AdoMet_MTases"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.150","properties":[{"key":"EntryName","value":"Vaccinia Virus protein VP39"},{"key":"MatchStatus","value":"1"}]},{"database":"HAMAP","id":"MF_01813","properties":[{"key":"EntryName","value":"MenG_UbiE_methyltr"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR029063","properties":[{"key":"EntryName","value":"SAM-dependent_MTases_sf"}]},{"database":"InterPro","id":"IPR004033","properties":[{"key":"EntryName","value":"UbiE/COQ5_MeTrFase"}]},{"database":"NCBIfam","id":"TIGR01934","properties":[{"key":"EntryName","value":"MenG_MenH_UbiE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR43591:SF24","properties":[{"key":"EntryName","value":"2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR43591","properties":[{"key":"EntryName","value":"METHYLTRANSFERASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01209","properties":[{"key":"EntryName","value":"Ubie_methyltran"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF53335","properties":[{"key":"EntryName","value":"S-adenosyl-L-methionine-dependent methyltransferases"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51608","properties":[{"key":"EntryName","value":"SAM_MT_UBIE"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MRKQNQDRTLETPAPGKKKKITQYFDAIGQRYDLADTLMSFGLHFSWRKNSLRQLDIKAGYRILDLCGGAGEFARRIAGTGTKGLPVVCDLSRTMLATGKNKSTGPARQNRIQWVQSDAEQLGFADNAFDAVIVGYGIRNLENLHHGLQEMHRVLIPGGTLVIMEFSIPQNRWLRTLYHWYSFKIMPTFGKVITGEKAPFIYLAESIRCFPAPERVQRILESAGFIRVTFQRLSNGLVTVYSATKQNNIFTSKLPA","length":256,"molWeight":28915,"crc64":"2293697ECA25D873","md5":"BDA385B1FB592AEB8A0CD010A04E7F7B"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"PATHWAY":1,"SIMILARITY":1,"CAUTION":1},"countByFeatureType":{"Binding site":2},"uniParcId":"UPI000172D813"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD94","uniProtkbId":"B2DD94_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-06-10","entryVersion":40,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28283.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"NCBIfam","id":"TIGR02170"}],"value":"FAD-dependent thymidylate synthase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"NCBIfam","id":"TIGR02170"}],"value":"2.1.1.148"}]}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"MBG0780205.1"}],"value":"thyX"},"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"MBG0780205.1"}],"value":"H0S81_09820"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00661"}],"value":"Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADPH + H(+) = dTMP + (6S)-5,6,7,8-tetrahydrofolate + NADP(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:29043"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:15636"},{"database":"ChEBI","id":"CHEBI:57453"},{"database":"ChEBI","id":"CHEBI:57783"},{"database":"ChEBI","id":"CHEBI:58349"},{"database":"ChEBI","id":"CHEBI:63528"},{"database":"ChEBI","id":"CHEBI:246422"}],"ecNumber":"2.1.1.148","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00661"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"FAD","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00661"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:57692"}}]}],"features":[{"type":"Motif","location":{"start":{"value":77,"modifier":"EXACT"},"end":{"value":87,"modifier":"EXACT"}},"description":"ThyX motif","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00661"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00661"}],"id":"KW-0274","category":"Ligand","name":"FAD"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00661"}],"id":"KW-0285","category":"Ligand","name":"Flavoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00661"},{"evidenceCode":"ECO:0000313","source":"EMBL","id":"MBG0780205.1"}],"id":"KW-0489","category":"Molecular function","name":"Methyltransferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00661"}],"id":"KW-0545","category":"Biological process","name":"Nucleotide biosynthesis"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00661"},{"evidenceCode":"ECO:0000313","source":"EMBL","id":"MBG0780205.1"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28283.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28283.1"}]},{"referenceNumber":2,"citation":{"id":"CI-EMFRD4UD101E7","citationType":"submission","authors":["Lahme S.","Mand J.","Longwell J.","Smith R.","Enning D."],"title":"Severe corrosion of carbon steel in oil field produced water can be linked to methanogenic archaea containing a special type of NiFe hydrogenase.","publicationDate":"JUL-2020","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"MBG0780205.1"}],"value":"MIC098Bin6","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"MBG0780205.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28283.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"JACCQK010000622","properties":[{"key":"ProteinId","value":"MBG0780205.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD94","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0050660","properties":[{"key":"GoTerm","value":"F:flavin adenine dinucleotide binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0070402","properties":[{"key":"GoTerm","value":"F:NADPH binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0050797","properties":[{"key":"GoTerm","value":"F:thymidylate synthase (FAD) activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0004799","properties":[{"key":"GoTerm","value":"F:thymidylate synthase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006231","properties":[{"key":"GoTerm","value":"P:dTMP biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"CDD","id":"cd20175","properties":[{"key":"EntryName","value":"ThyX"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.1360.170","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003669","properties":[{"key":"EntryName","value":"Thymidylate_synthase_ThyX"}]},{"database":"InterPro","id":"IPR036098","properties":[{"key":"EntryName","value":"Thymidylate_synthase_ThyX_sf"}]},{"database":"NCBIfam","id":"TIGR02170","properties":[{"key":"EntryName","value":"thyX"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR34934","properties":[{"key":"EntryName","value":"FLAVIN-DEPENDENT THYMIDYLATE SYNTHASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR34934:SF1","properties":[{"key":"EntryName","value":"FLAVIN-DEPENDENT THYMIDYLATE SYNTHASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02511","properties":[{"key":"EntryName","value":"Thy1"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF69796","properties":[{"key":"EntryName","value":"Thymidylate synthase-complementing protein Thy1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51331","properties":[{"key":"EntryName","value":"THYX"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKIIDQSHEIISLPDNLLQVIEAAGRTCYKSEDKITSDSATGFVARMRDRGHHAMIEFGDIIVRFVTNRGVTHELVRHRLCSFAQESTRYVRYDGKMEFIRPCWWDACTPAQQTLWQQAMADAENRYLSLLESGWRPEQAREVLPNSLKTEIVVKGNIREWRHIFTLRCAKKAHPQIRALMGPLLSALKEQLPVVFDDLVF","length":201,"molWeight":23239,"crc64":"3960D00C9C9BBD0C","md5":"D755A38F150ED7E960D9A3C384048E34"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"COFACTOR":1},"countByFeatureType":{"Motif":1},"uniParcId":"UPI000172D817"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD95","uniProtkbId":"B2DD95_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-06-10","entryVersion":54,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28284.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012438"}],"value":"histidine kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012438"}],"value":"2.7.13.3"}]},"flag":"Fragment"},"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.","ecNumber":"2.7.13.3","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00000085"}]}},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004651"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004651"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]}],"features":[{"type":"Transmembrane","location":{"start":{"value":14,"modifier":"EXACT"},"end":{"value":36,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":65,"modifier":"EXACT"},"end":{"value":86,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Domain","location":{"start":{"value":102,"modifier":"EXACT"},"end":{"value":320,"modifier":"EXACT"}},"description":"Histidine kinase","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50109"}]},{"type":"Modified residue","location":{"start":{"value":105,"modifier":"EXACT"},"end":{"value":105,"modifier":"EXACT"}},"description":"Phosphohistidine; by autocatalysis","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}]},{"type":"Non-terminal residue","location":{"start":{"value":335,"modifier":"EXACT"},"end":{"value":335,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28284.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022777"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022553"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00107"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28284.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28284.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28284.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD95","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0004721","properties":[{"key":"GoTerm","value":"F:phosphoprotein phosphatase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0000155","properties":[{"key":"GoTerm","value":"F:phosphorelay sensor kinase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016036","properties":[{"key":"GoTerm","value":"P:cellular response to phosphate starvation"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd00082","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.287.130","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.565.10","properties":[{"key":"EntryName","value":"Histidine kinase-like ATPase, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR050351","properties":[{"key":"EntryName","value":"BphY/WalK/GraS-like"}]},{"database":"InterPro","id":"IPR036890","properties":[{"key":"EntryName","value":"HATPase_C_sf"}]},{"database":"InterPro","id":"IPR003594","properties":[{"key":"EntryName","value":"HATPase_dom"}]},{"database":"InterPro","id":"IPR005467","properties":[{"key":"EntryName","value":"His_kinase_dom"}]},{"database":"InterPro","id":"IPR003661","properties":[{"key":"EntryName","value":"HisK_dim/P_dom"}]},{"database":"InterPro","id":"IPR036097","properties":[{"key":"EntryName","value":"HisK_dim/P_sf"}]},{"database":"InterPro","id":"IPR004358","properties":[{"key":"EntryName","value":"Sig_transdc_His_kin-like_C"}]},{"database":"PANTHER","id":"PTHR45453:SF2","properties":[{"key":"EntryName","value":"HISTIDINE KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR45453","properties":[{"key":"EntryName","value":"PHOSPHATE REGULON SENSOR PROTEIN PHOR"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02518","properties":[{"key":"EntryName","value":"HATPase_c"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00512","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00344","properties":[{"key":"EntryName","value":"BCTRLSENSOR"}]},{"database":"SMART","id":"SM00387","properties":[{"key":"EntryName","value":"HATPase_c"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00388","properties":[{"key":"EntryName","value":"HisKA"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF55874","properties":[{"key":"EntryName","value":"ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF47384","properties":[{"key":"EntryName","value":"Homodimeric domain of signal transducing histidine kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50109","properties":[{"key":"EntryName","value":"HIS_KIN"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MQILNPSRWYLHPVFIFACSIIALATFLVLTVSLYMEIRSALETVIVRFHIDPELIFPSKTGMTILVLSLLITVVLAGILLAFIYYQKTVNLFRLQHNFIYNFTHELKTPVTSLRLYLETFVRHPLKPEDIKRYSKSMLEDINRLTDNINRILNMARIESQNFDSQVTRKSLVEVVDTFCQKNDSLFRECDIRILNPTGGRFEYPVNLFLFEMLLMNIVSNAIKYNLSDRPQLTIVFKPHLQKVTIDFIDNGIGVDRHETKKIFRKFYQSDRENRERVSGSGLGLYLVSSIAKIHGWRVSVFSEGKGCGAKFTITIPRNAIANVREKNIGSGEKK","length":335,"molWeight":38674,"crc64":"F6FCAE38F1F7B733","md5":"E8610AB7D110337E12AC696E0D314796"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Transmembrane":2,"Domain":1,"Modified residue":1,"Non-terminal residue":1},"uniParcId":"UPI000172D818"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD61","uniProtkbId":"B2DD61_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-06-10","entryVersion":27,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28250.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28250.1"}],"value":"Phosphotransferase"}}],"flag":"Fragment"},"features":[{"type":"Domain","location":{"start":{"value":26,"modifier":"EXACT"},"end":{"value":234,"modifier":"EXACT"}},"description":"Aminoglycoside phosphotransferase","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF01636"}]},{"type":"Non-terminal residue","location":{"start":{"value":300,"modifier":"EXACT"},"end":{"value":300,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28250.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28250.1"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28250.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28250.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28250.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD61","properties":[{"key":"Description","value":"-"}]},{"database":"Gene3D","id":"3.90.1200.10","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR051678","properties":[{"key":"EntryName","value":"AGP_Transferase"}]},{"database":"InterPro","id":"IPR002575","properties":[{"key":"EntryName","value":"Aminoglycoside_PTrfase"}]},{"database":"InterPro","id":"IPR011009","properties":[{"key":"EntryName","value":"Kinase-like_dom_sf"}]},{"database":"PANTHER","id":"PTHR21310","properties":[{"key":"EntryName","value":"AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01636","properties":[{"key":"EntryName","value":"APH"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56112","properties":[{"key":"EntryName","value":"Protein kinase-like (PK-like)"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MPDTDRLEQIQQFLTDAGWVSPPFRVSFLAAGEYNANYRVDSNAGPCVLRINHGSQLGLGDDQIAYEFNVLKALADSGVTPKPLACHPHPDPLGGGALLMTFVPGTPLDYTRDLDTAARIFARVHTTCVPDGLIVQADPVNDIARESHGLLHRFADHPLKKEQAQILSYHDTLLSLARDTRPLFEAEPLCLVNTEVNSGNFLISPDRACLVDWEKAVVSCRYQDLGHFMVPTTTLWKTDILLTPADKKTFLQTYHQQACPDMLFNDLMEKSRVMEKTILLRALSWCFMAWYEYTHTNRPM","length":300,"molWeight":33731,"crc64":"A1CD8D2D0C45F4C9","md5":"0C074F0272BB4E95DA815698D0F160BD"},"extraAttributes":{"countByFeatureType":{"Domain":1,"Non-terminal residue":1},"uniParcId":"UPI000172D7F6"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD62","uniProtkbId":"B2DD62_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2008-06-10","entryVersion":50,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28251.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28251.1"}],"value":"ATP-binding protein of amino acid ABC transporter"}}]},"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004202"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004202"}],"value":"Peripheral membrane protein","id":"SL-9903"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00005417"}],"value":"Belongs to the ABC transporter superfamily"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":218,"modifier":"EXACT"}},"description":"ABC transporter","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50893"}]},{"type":"Binding site","location":{"start":{"value":20,"modifier":"EXACT"},"end":{"value":27,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00434"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022970"}],"id":"KW-0029","category":"Biological process","name":"Amino-acid transport"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00434"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00434"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022448"}],"id":"KW-0813","category":"Biological process","name":"Transport"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28251.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28251.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28251.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD62","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0015424","properties":[{"key":"GoTerm","value":"F:ABC-type amino acid transporter activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0016887","properties":[{"key":"GoTerm","value":"F:ATP hydrolysis activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.40.50.300","properties":[{"key":"EntryName","value":"P-loop containing nucleotide triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003593","properties":[{"key":"EntryName","value":"AAA+_ATPase"}]},{"database":"InterPro","id":"IPR030679","properties":[{"key":"EntryName","value":"ABC_ATPase_HisP-typ"}]},{"database":"InterPro","id":"IPR003439","properties":[{"key":"EntryName","value":"ABC_transporter-like_ATP-bd"}]},{"database":"InterPro","id":"IPR017871","properties":[{"key":"EntryName","value":"ABC_transporter-like_CS"}]},{"database":"InterPro","id":"IPR050086","properties":[{"key":"EntryName","value":"MetN_ABC_transporter-like"}]},{"database":"InterPro","id":"IPR027417","properties":[{"key":"EntryName","value":"P-loop_NTPase"}]},{"database":"PANTHER","id":"PTHR43166","properties":[{"key":"EntryName","value":"AMINO ACID IMPORT ATP-BINDING PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR43166:SF9","properties":[{"key":"EntryName","value":"GLUTAMATE_ASPARTATE IMPORT ATP-BINDING PROTEIN GLTL"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00005","properties":[{"key":"EntryName","value":"ABC_tran"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF039085","properties":[{"key":"EntryName","value":"ABC_ATPase_HisP"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00382","properties":[{"key":"EntryName","value":"AAA"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52540","properties":[{"key":"EntryName","value":"P-loop containing nucleoside triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00211","properties":[{"key":"EntryName","value":"ABC_TRANSPORTER_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50893","properties":[{"key":"EntryName","value":"ABC_TRANSPORTER_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MVLKDISLEIRQGEILAVIGPSGAGKSTFIRCLNGLEKVDKGSVTVDGQPVTSFTSVAGRMGMVFQQFNLFPHYTAIENIAAPLRTIKNMPRTRARDRAAELLESVKLADKASQYPSTLSGGQQQRLAIARALSMSPDIMLFDEPTSSLDPELAHEVFDTIQTLARSHMTLVLVTHQMNMVKNFATRVLFLENGGIFFDGTFEDLTSATDPRIRQFLKKIYP","length":222,"molWeight":24564,"crc64":"309036E4A916D541","md5":"45B6D2D9D4E57C4009FBE0F1E8B2D6AB"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Domain":1,"Binding site":1},"uniParcId":"UPI000172D7F7"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD64","uniProtkbId":"B2DD64_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2008-06-10","entryVersion":24,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28253.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28253.1"}],"value":"Periplasmic amino acid-binding protein of amino acid ABC transporter"}}]},"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":21,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":22,"modifier":"EXACT"},"end":{"value":262,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5052105014"},{"type":"Domain","location":{"start":{"value":38,"modifier":"EXACT"},"end":{"value":262,"modifier":"EXACT"}},"description":"Solute-binding protein family 3/N-terminal","evidences":[{"evidenceCode":"ECO:0000259","source":"SMART","id":"SM00062"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28253.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28253.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28253.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD64","properties":[{"key":"Description","value":"-"}]},{"database":"CDD","id":"cd13530","properties":[{"key":"EntryName","value":"PBP2_peptides_like"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.190.10","properties":[{"key":"EntryName","value":"Periplasmic binding protein-like II"},{"key":"MatchStatus","value":"2"}]},{"database":"InterPro","id":"IPR001638","properties":[{"key":"EntryName","value":"Solute-binding_3/MltF_N"}]},{"database":"PANTHER","id":"PTHR35936:SF34","properties":[{"key":"EntryName","value":"ABC TRANSPORTER EXTRACELLULAR-BINDING PROTEIN YCKB-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR35936","properties":[{"key":"EntryName","value":"MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00497","properties":[{"key":"EntryName","value":"SBP_bac_3"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00062","properties":[{"key":"EntryName","value":"PBPb"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF53850","properties":[{"key":"EntryName","value":"Periplasmic binding protein-like II"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKKKLFASFILALAVIAVTWTCAAAGDSRWSKIEQSGSITVGNCPEYPPFSFRNTSGLVEGFDSDFARALGNALGVDVVIKDTAWEGLVAGMKKGDHDIIISCMSPEEATQASDSVNMSNPYYQLSEIIVTRSDVTDITTKEDLAGRIVGVQANSTSEVAGDSLADMDIKVKDLRRYNRNSEALIDLKNKRVDAVVVGFAYAATKIKDSPDLKIINDPVRSVDIVVVLDHGEDELTEKINQAIDTVKSNGDFDRIHDKWLAL","length":262,"molWeight":28546,"crc64":"62D36FD42AD682FC","md5":"353DDFD1E221456AE2DAB171AF3E6698"},"extraAttributes":{"countByFeatureType":{"Signal":1,"Chain":1,"Domain":1},"uniParcId":"UPI000172D7F9"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD65","uniProtkbId":"B2DD65_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2025-04-02","lastSequenceUpdateDate":"2008-06-10","entryVersion":11,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28254.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28254.1"}],"value":"Uncharacterized protein"}}]},"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28254.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28254.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28254.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD65","properties":[{"key":"Description","value":"-"}]}],"sequence":{"value":"MTLDALSSLYGLLGSQPFLLDLVKNKDRVKQRVREMTDVSLAFYDYLYDFLVENGYGQSGSWFQVFCEGKFESVRCDFSIMLSREMFCELEKIKDKGMLLEIVCHKVDDAVLAARTLGPDGLYLMIEPRFSSPDQASHAVDRVYNACR","length":148,"molWeight":16931,"crc64":"53E0CAEBC24D3951","md5":"BE8E904561F0915F48A3DD18D05558E7"},"extraAttributes":{"uniParcId":"UPI000172D7FA"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD66","uniProtkbId":"B2DD66_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2025-04-02","lastSequenceUpdateDate":"2008-06-10","entryVersion":11,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28255.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28255.1"}],"value":"Uncharacterized protein"}}]},"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28255.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28255.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28255.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD66","properties":[{"key":"Description","value":"-"}]}],"sequence":{"value":"MPNRMICSEKICDTESRLRHRMFWENRSTGVPLVYAVSDNPGFIPAPWRTSLPRKEWDLLPDWHLNRIGNFLEGTCFFGDAMPMASLMVGLDITNTAVLAGGDYDYSCTGDFIDFKSGDLDLAQPVPDFTPDHPLAIDLKQCY","length":143,"molWeight":16163,"crc64":"A78904CE2C526A2A","md5":"DA310591468788E5C79C5848146199BC"},"extraAttributes":{"uniParcId":"UPI000172D7FB"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD67","uniProtkbId":"B2DD67_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2025-04-02","lastSequenceUpdateDate":"2008-06-10","entryVersion":19,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28256.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0008006","source":"Google","id":"ProtNLM"}],"value":"DUF523 domain-containing protein"}}},"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28256.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28256.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28256.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD67","properties":[{"key":"Description","value":"-"}]},{"database":"InterPro","id":"IPR054648","properties":[{"key":"EntryName","value":"TudS-rel"}]},{"database":"NCBIfam","id":"NF045597","properties":[{"key":"EntryName","value":"TudS_rel_CD3072"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKRGKKIIFVSHCLLNVNVKVMGLAAHPGAVKELVCFLMDHDTAMVQLPCPESEILGLCRWGHVKDQLAYPFFKNRCRHLLAPFIRQIHMYKENGYLLKGVIGIDGSPSCGVHKTCRSNQWSGDFLDKEDTWKKIQTLEWQADPGIFIEIFQALLMENNLPLDFFAVDESEIDMSLSSLFKTLSPVLKR","length":189,"molWeight":21552,"crc64":"07534BDAA6D90B31","md5":"01EFB0A3A2CD7646E16A1608D01506D8"},"extraAttributes":{"uniParcId":"UPI000172D7FC"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD68","uniProtkbId":"B2DD68_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2008-06-10","entryVersion":67,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28257.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"MBG0778433.1"}],"value":"Cold-shock protein"}}]},"genes":[{"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"MBG0778433.1"}],"value":"H0S81_00670"}]}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004496"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU000408"}],"value":"Cytoplasm","id":"SL-0086"}}]}],"features":[{"type":"Domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":66,"modifier":"EXACT"}},"description":"CSD","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51857"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022490"}],"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28257.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28257.1"}]},{"referenceNumber":2,"citation":{"id":"CI-EMFRD4UD101E7","citationType":"submission","authors":["Lahme S.","Mand J.","Longwell J.","Smith R.","Enning D."],"title":"Severe corrosion of carbon steel in oil field produced water can be linked to methanogenic archaea containing a special type of NiFe hydrogenase.","publicationDate":"JUL-2020","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"MBG0778433.1"}],"value":"MIC098Bin6","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"MBG0778433.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28257.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"JACCQK010000023","properties":[{"key":"ProteinId","value":"MBG0778433.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD68","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0003676","properties":[{"key":"GoTerm","value":"F:nucleic acid binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd04458","properties":[{"key":"EntryName","value":"CSP_CDS"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.40.50.140:FF:000006","properties":[{"key":"EntryName","value":"Cold shock protein CspC"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"6.20.370.130","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.40.50.140","properties":[{"key":"EntryName","value":"Nucleic acid-binding proteins"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR012156","properties":[{"key":"EntryName","value":"Cold_shock_CspA"}]},{"database":"InterPro","id":"IPR050181","properties":[{"key":"EntryName","value":"Cold_shock_domain"}]},{"database":"InterPro","id":"IPR011129","properties":[{"key":"EntryName","value":"CSD"}]},{"database":"InterPro","id":"IPR019844","properties":[{"key":"EntryName","value":"CSD_CS"}]},{"database":"InterPro","id":"IPR002059","properties":[{"key":"EntryName","value":"CSD_DNA-bd"}]},{"database":"InterPro","id":"IPR012340","properties":[{"key":"EntryName","value":"NA-bd_OB-fold"}]},{"database":"PANTHER","id":"PTHR11544","properties":[{"key":"EntryName","value":"COLD SHOCK DOMAIN CONTAINING PROTEINS"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00313","properties":[{"key":"EntryName","value":"CSD"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF002599","properties":[{"key":"EntryName","value":"Cold_shock_A"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00050","properties":[{"key":"EntryName","value":"COLDSHOCK"}]},{"database":"SMART","id":"SM00357","properties":[{"key":"EntryName","value":"CSP"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF50249","properties":[{"key":"EntryName","value":"Nucleic acid-binding proteins"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00352","properties":[{"key":"EntryName","value":"CSD_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51857","properties":[{"key":"EntryName","value":"CSD_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MANGTVKWFNDAKGFGFIEQEDGGKDVFVHHSGINAMGFKSLNEGDRVSFDISEGQRGPAATNVTVV","length":67,"molWeight":7189,"crc64":"917316E0C375E74C","md5":"5A0216ADC7F48A12A319596D83AA092B"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Domain":1},"uniParcId":"UPI000172D7FD"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD69","uniProtkbId":"B2DD69_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2008-06-10","entryVersion":23,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28258.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF01850"}],"value":"PIN domain-containing protein"}}},"comments":[{"commentType":"COFACTOR","cofactors":[{"name":"Mg(2+)","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001946"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:18420"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00038093"}],"value":"Belongs to the PINc/VapC protein family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":100,"modifier":"EXACT"},"end":{"value":167,"modifier":"EXACT"}},"description":"PIN","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF01850"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022801"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022842"}],"id":"KW-0460","category":"Ligand","name":"Magnesium"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022722"}],"id":"KW-0540","category":"Molecular function","name":"Nuclease"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022649"}],"id":"KW-1277","category":"Biological process","name":"Toxin-antitoxin system"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28258.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28258.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28258.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD69","properties":[{"key":"Description","value":"-"}]},{"database":"Gene3D","id":"3.40.50.1010","properties":[{"key":"EntryName","value":"5'-nuclease"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR029060","properties":[{"key":"EntryName","value":"PIN-like_dom_sf"}]},{"database":"InterPro","id":"IPR002716","properties":[{"key":"EntryName","value":"PIN_dom"}]},{"database":"InterPro","id":"IPR050556","properties":[{"key":"EntryName","value":"Type_II_TA_system_RNase"}]},{"database":"PANTHER","id":"PTHR33653","properties":[{"key":"EntryName","value":"RIBONUCLEASE VAPC2"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33653:SF1","properties":[{"key":"EntryName","value":"RIBONUCLEASE VAPC2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01850","properties":[{"key":"EntryName","value":"PIN"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF88723","properties":[{"key":"EntryName","value":"PIN domain-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MIKQIGQFERQLEFIDKTQVVEGIPHFQIRHHIVIDLFIVFGIPIPAAHVADHGNQFKIPQDVYQPGFQGPFRGIDHLFVFGIPDNPLKCQVVIVCQYRIRGVQKEVQVLIDEKTGFNFHSLDNRTSDTATKLLKTYRLSHGLLIADALIAATAIVNGIQLISKNQKDYRFIEQLELLEYPSSIL","length":185,"molWeight":21089,"crc64":"66A910A96205378F","md5":"D28979E08E02D210ABE19242A62B04C2"},"extraAttributes":{"countByCommentType":{"COFACTOR":1,"SIMILARITY":1},"countByFeatureType":{"Domain":1},"uniParcId":"UPI000172D7FE"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD70","uniProtkbId":"B2DD70_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2008-06-10","entryVersion":28,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28259.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28259.1"}],"value":"Solute-binding protein of iron ABC transporter"}}]},"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":28,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":29,"modifier":"EXACT"},"end":{"value":404,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5052286272"},{"type":"Domain","location":{"start":{"value":55,"modifier":"EXACT"},"end":{"value":361,"modifier":"EXACT"}},"description":"Fe/B12 periplasmic-binding","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50983"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00344"}],"id":"KW-0574","category":"Cellular component","name":"Periplasm"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00344"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00344"}],"id":"KW-0813","category":"Biological process","name":"Transport"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28259.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28259.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28259.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD70","properties":[{"key":"Description","value":"-"}]},{"database":"Gene3D","id":"3.40.50.1980","properties":[{"key":"EntryName","value":"Nitrogenase molybdenum iron protein domain"},{"key":"MatchStatus","value":"2"}]},{"database":"InterPro","id":"IPR050902","properties":[{"key":"EntryName","value":"ABC_Transporter_SBP"}]},{"database":"InterPro","id":"IPR002491","properties":[{"key":"EntryName","value":"ABC_transptr_periplasmic_BD"}]},{"database":"PANTHER","id":"PTHR30535:SF34","properties":[{"key":"EntryName","value":"MOLYBDATE-BINDING PROTEIN MOLA"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30535","properties":[{"key":"EntryName","value":"VITAMIN B12-BINDING PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01497","properties":[{"key":"EntryName","value":"Peripla_BP_2"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF53807","properties":[{"key":"EntryName","value":"Helical backbone' metal receptor"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50983","properties":[{"key":"EntryName","value":"FE_B12_PBP"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MIMMRLRFFFEWFVCLGILLTAAPDIYASENSDSFRSVTDQRGVSVKVPMKIERVVTICDGLVESVMTALGVQNSIVGLGSACIPKHWEYTYPTVAGESYDYTDGMNTVTFLNPFFMDLPLVAQSGTGINYETLASLNPDVVFLRAGSCTLSANDESTHKTIRMIESLGIPLVVLFGPNMTKNPKMDSISEEIRIIGRALGNEQKATALAEYLEKQVRFVMDRTREIPEDQKPSVLLFGLSPKSREAGGTGHVRGLNTIDSWLVETVVNARNAFRTKGSWNILGTEQVLAIDPDVIVLITAWGYHPPRELYEAPYYQNLKDLRAVKNRRVTALPWTPCNCDKRVEYPIDVMIIAKAAYPEKFADVDLNVWLLDFYQNVYGVDPNTAAQLRAVQWMNWVTEKPPH","length":404,"molWeight":45374,"crc64":"0CA1205087208CD2","md5":"BE6B434DF4E6CB0A45F57590D5F17B98"},"extraAttributes":{"countByFeatureType":{"Signal":1,"Chain":1,"Domain":1},"uniParcId":"UPI000172D7FF"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD71","uniProtkbId":"B2DD71_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2008-06-10","entryVersion":49,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28260.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28260.1"}],"value":"ATP-binding protein of iron ABC transporter"}}]},"features":[{"type":"Domain","location":{"start":{"value":2,"modifier":"EXACT"},"end":{"value":237,"modifier":"EXACT"}},"description":"ABC transporter","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50893"}]},{"type":"Binding site","location":{"start":{"value":34,"modifier":"EXACT"},"end":{"value":41,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00434"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022840"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00434"}],"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022741"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00434"}],"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022448"}],"id":"KW-0813","category":"Biological process","name":"Transport"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28260.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28260.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28260.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD71","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0016887","properties":[{"key":"GoTerm","value":"F:ATP hydrolysis activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd03214","properties":[{"key":"EntryName","value":"ABC_Iron-Siderophores_B12_Hemin"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.40.50.300:FF:000134","properties":[{"key":"EntryName","value":"Iron-enterobactin ABC transporter ATP-binding protein"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.300","properties":[{"key":"EntryName","value":"P-loop containing nucleotide triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003593","properties":[{"key":"EntryName","value":"AAA+_ATPase"}]},{"database":"InterPro","id":"IPR003439","properties":[{"key":"EntryName","value":"ABC_transporter-like_ATP-bd"}]},{"database":"InterPro","id":"IPR017871","properties":[{"key":"EntryName","value":"ABC_transporter-like_CS"}]},{"database":"InterPro","id":"IPR050153","properties":[{"key":"EntryName","value":"Metal_Ion_Import_ABC"}]},{"database":"InterPro","id":"IPR027417","properties":[{"key":"EntryName","value":"P-loop_NTPase"}]},{"database":"PANTHER","id":"PTHR42734:SF19","properties":[{"key":"EntryName","value":"IRON COMPOUNDS ABC TRANSPORTER, ATP-BINDING PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42734","properties":[{"key":"EntryName","value":"METAL TRANSPORT SYSTEM ATP-BINDING PROTEIN TM_0124-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00005","properties":[{"key":"EntryName","value":"ABC_tran"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00382","properties":[{"key":"EntryName","value":"AAA"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52540","properties":[{"key":"EntryName","value":"P-loop containing nucleoside triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00211","properties":[{"key":"EntryName","value":"ABC_TRANSPORTER_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50893","properties":[{"key":"EntryName","value":"ABC_TRANSPORTER_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MLQVHNLHFGYGKTPILNGVSFEAAPGQLLGLFGPNGSGKTTLFKCCLKFLKYNSGMVIMDDMDIQKASVAQMARHAAYVPQEHKPPFPYLVREVVLMGRTPHLGGIFGISKRDKAIALEALHMLDIRNLADRAYNRLSGGQRQMVLIARAIAQETKLLFLDEPTSALDFSNQIRIWKMLRRITAQGITVIACSHDPNHVIWFCHKVVVLDGKGIVIQGTTDEVMTEKVLNGIYHEICTTKEVDGIRMVVPRGIT","length":255,"molWeight":28379,"crc64":"C06FAEF9205CD1C3","md5":"00E63CF93F9DAC7E34A0CB3834F4150C"},"extraAttributes":{"countByFeatureType":{"Domain":1,"Binding site":1},"uniParcId":"UPI000172D800"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD72","uniProtkbId":"B2DD72_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2008-06-10","entryVersion":29,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28261.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28261.1"}],"value":"Methyltransferase"}}]},"features":[{"type":"Domain","location":{"start":{"value":5,"modifier":"EXACT"},"end":{"value":238,"modifier":"EXACT"}},"description":"Tetrapyrrole methylase","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF00590"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022603"},{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28261.1"}],"id":"KW-0489","category":"Molecular function","name":"Methyltransferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022691"}],"id":"KW-0949","category":"Ligand","name":"S-adenosyl-L-methionine"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"},{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28261.1"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28261.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28261.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28261.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD72","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0004851","properties":[{"key":"GoTerm","value":"F:uroporphyrin-III C-methyltransferase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0019354","properties":[{"key":"GoTerm","value":"P:siroheme biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd11724","properties":[{"key":"EntryName","value":"TP_methylase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.1010.10","properties":[{"key":"EntryName","value":"Cobalt-precorrin-4 Transmethylase, Domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.950.10","properties":[{"key":"EntryName","value":"Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR000878","properties":[{"key":"EntryName","value":"4pyrrol_Mease"}]},{"database":"InterPro","id":"IPR035996","properties":[{"key":"EntryName","value":"4pyrrol_Methylase_sf"}]},{"database":"InterPro","id":"IPR014777","properties":[{"key":"EntryName","value":"4pyrrole_Mease_sub1"}]},{"database":"InterPro","id":"IPR014776","properties":[{"key":"EntryName","value":"4pyrrole_Mease_sub2"}]},{"database":"InterPro","id":"IPR050161","properties":[{"key":"EntryName","value":"Siro_Cobalamin_biosynth"}]},{"database":"PANTHER","id":"PTHR45790:SF3","properties":[{"key":"EntryName","value":"S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR45790","properties":[{"key":"EntryName","value":"SIROHEME SYNTHASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00590","properties":[{"key":"EntryName","value":"TP_methylase"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF53790","properties":[{"key":"EntryName","value":"Tetrapyrrole methylase"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKKGKLFVIGTGPGGPDQTTLEALRCIEMADIILCPEETKKHFASYIDKKPVFCNPWKGLFDYKGKPWRELVHSDPSLIESFKKERIRIREEIVGYVKEKMANGKNVALLENGDPCLFGPSHWFIEGFEVDEVDILPGVGTFSAAMAALKKSSIPAYDTRFVLQTSPLFLTENDQDNDIFEDLSRYPATMVFYMALWNLENLIKRLTDHYPENLPVAVIYHLGHDEKQNIVQGTLKNITEKVQGIKEDFAGLIIVGKCLEGAGYRSKTENLVRI","length":274,"molWeight":31002,"crc64":"62855B0344544F33","md5":"E706C3CBFDEF1C4DC6E79E26597B0733"},"extraAttributes":{"countByFeatureType":{"Domain":1},"uniParcId":"UPI000172D801"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD73","uniProtkbId":"B2DD73_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-06-10","entryVersion":49,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28262.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28262.1"}],"value":"Permease protein of iron ABC transporter"}}]},"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004651"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004651"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00096319"}],"value":"Belongs to the binding protein-dependent transport system permease family. FecCD subfamily"}],"commentType":"SIMILARITY"}],"features":[{"type":"Transmembrane","location":{"start":{"value":62,"modifier":"EXACT"},"end":{"value":84,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":121,"modifier":"EXACT"},"end":{"value":141,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":153,"modifier":"EXACT"},"end":{"value":174,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":180,"modifier":"EXACT"},"end":{"value":196,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":208,"modifier":"EXACT"},"end":{"value":230,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":250,"modifier":"EXACT"},"end":{"value":271,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":297,"modifier":"EXACT"},"end":{"value":318,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":338,"modifier":"EXACT"},"end":{"value":354,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":366,"modifier":"EXACT"},"end":{"value":384,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022448"}],"id":"KW-0813","category":"Biological process","name":"Transport"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28262.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28262.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28262.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD73","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0022857","properties":[{"key":"GoTerm","value":"F:transmembrane transporter activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0033214","properties":[{"key":"GoTerm","value":"P:siderophore-iron import into cell"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd06550","properties":[{"key":"EntryName","value":"TM_ABC_iron-siderophores_like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.3470.10:FF:000001","properties":[{"key":"EntryName","value":"Vitamin B12 ABC transporter permease BtuC"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.3470.10","properties":[{"key":"EntryName","value":"ABC transporter involved in vitamin B12 uptake, BtuC"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR037294","properties":[{"key":"EntryName","value":"ABC_BtuC-like"}]},{"database":"InterPro","id":"IPR000522","properties":[{"key":"EntryName","value":"ABC_transptr_permease_BtuC"}]},{"database":"PANTHER","id":"PTHR30472","properties":[{"key":"EntryName","value":"FERRIC ENTEROBACTIN TRANSPORT SYSTEM PERMEASE PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30472:SF70","properties":[{"key":"EntryName","value":"MOLYBDATE IMPORT SYSTEM PERMEASE PROTEIN MOLB"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01032","properties":[{"key":"EntryName","value":"FecCD"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF81345","properties":[{"key":"EntryName","value":"ABC transporter involved in vitamin B12 uptake, BtuC"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKDSEIIPLNEQNTMELEKNTSDETPSRLTRAKSEFIYVFQREKDIEEEKDAEVFSEKWKMLLLFSLVALLFLTAALSMTMGAYKITIADVYQVLSAHLNPYQISDQLNPLQKTIVWDLRFPRILLAMAIGIGLATAGAVFQGCFRNPLVEPYILGVSSGAAFGAALGIVFPAFYFSVQISAFLFGMIAVMGTYSLGRIRGETPVITLILAGVIIGSVFSALVSILKYVAHDTALREIVFWLMGGFYYTTWKDVLIVSPVVLICFVLQWSLGWKLNILSMGDEEARALGIHPERYKLILIIMATLCTAVSVSTVGIIAWVGLMMPHAARMVLGPDNRFVIPAAAMLGGVYLLVCDTLARTLTTAEIPIGILTSILGAPYLFYLLRSKGHTAFGG","length":394,"molWeight":43314,"crc64":"53CFB2BB6B54AE39","md5":"4C4F3927B5B400191FED2B06CF2962E1"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Transmembrane":9},"uniParcId":"UPI000172D802"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD74","uniProtkbId":"B2DD74_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-06-10","lastSequenceUpdateDate":"2008-06-10","entryVersion":42,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28263.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28263.1"}],"value":"TonB-dependent receptor"}}]},"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004571"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"value":"Cell outer membrane","id":"SL-0040"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004571"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003357"}],"value":"Belongs to the TonB-dependent receptor family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":65,"modifier":"EXACT"},"end":{"value":170,"modifier":"EXACT"}},"description":"TonB-dependent receptor plug","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF07715"}]},{"type":"Domain","location":{"start":{"value":221,"modifier":"EXACT"},"end":{"value":480,"modifier":"EXACT"}},"description":"TonB-dependent receptor-like beta-barrel","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF00593"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023237"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0998","category":"Cellular component","name":"Cell outer membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28263.1"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023077"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003357"}],"id":"KW-0798","category":"Domain","name":"TonB box"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022452"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-1134","category":"Domain","name":"Transmembrane beta strand"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022448"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0813","category":"Biological process","name":"Transport"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28263.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28263.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28263.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD74","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0009279","properties":[{"key":"GoTerm","value":"C:cell outer membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0015344","properties":[{"key":"GoTerm","value":"F:siderophore uptake transmembrane transporter activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0044718","properties":[{"key":"GoTerm","value":"P:siderophore transmembrane transport"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"Gene3D","id":"2.40.170.20","properties":[{"key":"EntryName","value":"TonB-dependent receptor, beta-barrel domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.170.130.10","properties":[{"key":"EntryName","value":"TonB-dependent receptor, plug domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR000531","properties":[{"key":"EntryName","value":"Beta-barrel_TonB"}]},{"database":"InterPro","id":"IPR036942","properties":[{"key":"EntryName","value":"Beta-barrel_TonB_sf"}]},{"database":"InterPro","id":"IPR012910","properties":[{"key":"EntryName","value":"Plug_dom"}]},{"database":"InterPro","id":"IPR037066","properties":[{"key":"EntryName","value":"Plug_dom_sf"}]},{"database":"InterPro","id":"IPR039426","properties":[{"key":"EntryName","value":"TonB-dep_rcpt-like"}]},{"database":"NCBIfam","id":"NF049947","properties":[{"key":"EntryName","value":"TonB_dep_PCPU"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30069","properties":[{"key":"EntryName","value":"TONB-DEPENDENT OUTER MEMBRANE RECEPTOR"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30069:SF28","properties":[{"key":"EntryName","value":"TONB-DEPENDENT RECEPTOR YNCD-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07715","properties":[{"key":"EntryName","value":"Plug"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00593","properties":[{"key":"EntryName","value":"TonB_dep_Rec_b-barrel"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56935","properties":[{"key":"EntryName","value":"Porins"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS52016","properties":[{"key":"EntryName","value":"TONB_DEPENDENT_REC_3"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MLTGFLSKVLSTLRLKIISALSGFLLVFLWGNILSAETGKETNQVYQLSPITVMAPQQGVEINVDKTIINMDDFRKAGTVRNLTDVLKEIGAVDVQRINPLISSPGDEVSIRGLNEGRLVIQIDGRRINHTGHNGRYIVDWSTLNMDDIERIEIIRGGHSVLHPFAIGGVINLITKKGQKTEDPKPDFSISGGYGSFETSHFRASVDGGAGNFLGYHLSASSQETDGYLRNNFQENKNINGHLTFFLPSDATLKLGAKFSDVTYGFPVVNDPSRGDYDAGYPTFLGTADQLRHLPSTLQFPGDPKPRWDKETHYLDAIFEIPFGPGTFSVHGFQTEGKRDTYYYRGTDFIEDFIDDRSRGFIAEYRDVNLFDRHSFTFGAEYQELGQPSGIRNIYIVRSLYVQDVIKLGDRWKITPGVRYYSLDKDTYFAWFESGGTSPAFPTTGKKETDKDWFPSLKIDFQANDTTALYAAVSRSYRLPCP","length":482,"molWeight":54039,"crc64":"075093E957894F98","md5":"65CBE1146F0A9FB2D4DE61F4C539E54C"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Domain":2},"uniParcId":"UPI000172D803"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD75","uniProtkbId":"B2DD75_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-06-10","entryVersion":26,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28264.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28264.1"}],"value":"Methyltransferase"}}]},"features":[{"type":"Domain","location":{"start":{"value":44,"modifier":"EXACT"},"end":{"value":140,"modifier":"EXACT"}},"description":"Methyltransferase type 11","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF08241"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28264.1"}],"id":"KW-0489","category":"Molecular function","name":"Methyltransferase"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28264.1"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28264.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28264.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28264.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD75","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0008757","properties":[{"key":"GoTerm","value":"F:S-adenosylmethionine-dependent methyltransferase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd02440","properties":[{"key":"EntryName","value":"AdoMet_MTases"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.150","properties":[{"key":"EntryName","value":"Vaccinia Virus protein VP39"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR013216","properties":[{"key":"EntryName","value":"Methyltransf_11"}]},{"database":"InterPro","id":"IPR029063","properties":[{"key":"EntryName","value":"SAM-dependent_MTases_sf"}]},{"database":"PANTHER","id":"PTHR43591","properties":[{"key":"EntryName","value":"METHYLTRANSFERASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF08241","properties":[{"key":"EntryName","value":"Methyltransf_11"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF53335","properties":[{"key":"EntryName","value":"S-adenosyl-L-methionine-dependent methyltransferases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MTSRSDFFDQRAENWEQAHYPGPVRERLQKLIQTFGVTPGETILDVGTGPGILIPYLEPLAGISGRVFAFDLSFPMVGQARRKTRADNDLVVQANVLEIPFGTGIFHRVICFAAFPHFEDPAIALQEMGRVLKPGGYLVIAHLMSRRELAAHHASHTGVEKDLLPHARQMAGLFLAAGFQEPEIKDMPGRYTAVARK","length":197,"molWeight":21832,"crc64":"D3A0018E77CE422B","md5":"527792823448FF1274D5A1F4751A5CCA"},"extraAttributes":{"countByFeatureType":{"Domain":1},"uniParcId":"UPI000172D804"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD77","uniProtkbId":"B2DD77_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"2008-06-10","entryVersion":48,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28266.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28266.1"}],"value":"TonB-dependent receptor"}}]},"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004571"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"value":"Cell outer membrane","id":"SL-0040"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004571"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003357"}],"value":"Belongs to the TonB-dependent receptor family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":21,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":22,"modifier":"EXACT"},"end":{"value":735,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5002777090"},{"type":"Domain","location":{"start":{"value":64,"modifier":"EXACT"},"end":{"value":155,"modifier":"EXACT"}},"description":"TonB-dependent receptor plug","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF07715"}]},{"type":"Domain","location":{"start":{"value":249,"modifier":"EXACT"},"end":{"value":697,"modifier":"EXACT"}},"description":"TonB-dependent receptor-like beta-barrel","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF00593"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023237"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0998","category":"Cellular component","name":"Cell outer membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023065"}],"id":"KW-0406","category":"Biological process","name":"Ion transport"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022496"}],"id":"KW-0410","category":"Biological process","name":"Iron transport"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28266.1"}],"id":"KW-0675","category":"Molecular function","name":"Receptor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023077"},{"evidenceCode":"ECO:0000256","source":"RuleBase","id":"RU003357"}],"id":"KW-0798","category":"Domain","name":"TonB box"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022452"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-1134","category":"Domain","name":"Transmembrane beta strand"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022448"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU01360"}],"id":"KW-0813","category":"Biological process","name":"Transport"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28266.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28266.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28266.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD77","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0009279","properties":[{"key":"GoTerm","value":"C:cell outer membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0015344","properties":[{"key":"GoTerm","value":"F:siderophore uptake transmembrane transporter activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"Gene3D","id":"2.40.170.20","properties":[{"key":"EntryName","value":"TonB-dependent receptor, beta-barrel domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.170.130.10","properties":[{"key":"EntryName","value":"TonB-dependent receptor, plug domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR000531","properties":[{"key":"EntryName","value":"Beta-barrel_TonB"}]},{"database":"InterPro","id":"IPR036942","properties":[{"key":"EntryName","value":"Beta-barrel_TonB_sf"}]},{"database":"InterPro","id":"IPR012910","properties":[{"key":"EntryName","value":"Plug_dom"}]},{"database":"InterPro","id":"IPR037066","properties":[{"key":"EntryName","value":"Plug_dom_sf"}]},{"database":"InterPro","id":"IPR039426","properties":[{"key":"EntryName","value":"TonB-dep_rcpt-like"}]},{"database":"PANTHER","id":"PTHR32552","properties":[{"key":"EntryName","value":"FERRICHROME IRON RECEPTOR-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR32552:SF68","properties":[{"key":"EntryName","value":"FERRICHROME OUTER MEMBRANE TRANSPORTER_PHAGE RECEPTOR"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07715","properties":[{"key":"EntryName","value":"Plug"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00593","properties":[{"key":"EntryName","value":"TonB_dep_Rec_b-barrel"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56935","properties":[{"key":"EntryName","value":"Porins"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS52016","properties":[{"key":"EntryName","value":"TONB_DEPENDENT_REC_3"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKFMQQFMAVCFVMAALSAGAGESGPDKVILDDVVVTGTKLVTPTKQTNETVYTGSEITRDGLDALGSKAAVSVYEAINILPGITVESIDPYGLAAEQKNIRVRGVRGFLGAMTVAGVPNYGGNPMGPREYIYDTENFDSIAVYKGAVPADLGTGVGARGGAVDLRPKWPEEEFGVNVSQGIGTHNYSRSFIRLDSGSLPRTGTGLSLSLSHTDAEKWKGPGDLGPRKNVNVMLRQPMPTGDEVKFWFNANDLNQDLYRPLTYSEVESLGSFYNKDYNSSLTGNKSDDINYYRYNRGDYANRDFLAEIPVTLSDTFRLKFKPYYTDEDTEILQGSASQGGIVIKRKRDIERYGMITQLDSHFSWGKASLGYWAEVSDMIIRQQNYDPITFAFKGYGMYMKSDDKGVAHSPFLKLAGSIGQFDWQAGLKYFHYTDPSSQGYVASAPDYTLKAASDLFREEKTYDEILPTLGVAYRLTDTVELNASYGRNQIRPYAYVPLVNIYNQNRTAFQAAGVTLDDMFSGYDMEISDNFEVGARFRFDRFEVVPTLFYSRHQNLLTTVYDPRVNLSYNQNVGDATGYGIEIESNFLINDHLNFFLNPSYTALTYDDDLTFQGAVRDTKDKQVLDTPEWTVKTGLIYTWKDFEIIPMIRYMSSRYGDAEHNEKVDDYVMADLKMGYTFNHFSFVDKLRLSLELTNLFDKEYVSVINAMDDSRAGNTSYYVGAPFTAMMTVSFDF","length":735,"molWeight":82526,"crc64":"DA0AE42987F90E3F","md5":"1C0C2556D67400223226AA3194BA1358"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Signal":1,"Chain":1,"Domain":2},"uniParcId":"UPI000172D806"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD78","uniProtkbId":"B2DD78_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2008-06-10","entryVersion":26,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28267.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF02663"}],"value":"Formylmethanofuran dehydrogenase subunit E domain-containing protein"}}},"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":29,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":30,"modifier":"EXACT"},"end":{"value":378,"modifier":"EXACT"}},"description":"Formylmethanofuran dehydrogenase subunit E domain-containing protein","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5054705190"},{"type":"Domain","location":{"start":{"value":213,"modifier":"EXACT"},"end":{"value":273,"modifier":"EXACT"}},"description":"Formylmethanofuran dehydrogenase subunit E","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF02663"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28267.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28267.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28267.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD78","properties":[{"key":"Description","value":"-"}]},{"database":"Gene3D","id":"3.30.1330.130","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003814","properties":[{"key":"EntryName","value":"FmdEsu_dom"}]},{"database":"Pfam","id":"PF02663","properties":[{"key":"EntryName","value":"FmdE"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF143555","properties":[{"key":"EntryName","value":"FwdE-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MTSMKHQHPVIMIFFLAVIITSWCGVCFGQKNSDPSSGESVYTRWKAAGQFAAGMSLEMIQTAAAAPDTENLIVLTNAGYAEIFGMSTQGALDGLTVVTGASRGKNTLVEIHAAARDPLWFAVYDRQSGFCAYLEMNRSDGSDSKLFPQPMSPEMFGIRTVERIDAAYLYQHATALEARLAGRIFGNNAFRVITIANAVASGATARVIRAFEFHDHYCPGVISGIFMADYVQTHFPPGSTGYFVHGTDPWCKEDALMVLLNATPGKKKYAVNYPSKADRANRLPEIQDAATIVYRQDDETRKWEAIILGFDWADTSCTKTGNVIIDKLCTDLWYLERIDTPEAFVKVLKTVALPDGVSPIDWAGPGIDPLQKMGLTVK","length":378,"molWeight":41475,"crc64":"862BDDC86545C415","md5":"BCF417989FBD21FD23A77DEC0539FF1F"},"extraAttributes":{"countByFeatureType":{"Signal":1,"Chain":1,"Domain":1},"uniParcId":"UPI000172D807"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD79","uniProtkbId":"B2DD79_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"2008-06-10","entryVersion":16,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28268.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF12654"}],"value":"DUF3786 domain-containing protein"}}},"features":[{"type":"Domain","location":{"start":{"value":27,"modifier":"EXACT"},"end":{"value":197,"modifier":"EXACT"}},"description":"DUF3786","evidences":[{"evidenceCode":"ECO:0000259","source":"Pfam","id":"PF12654"}]}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28268.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28268.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28268.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD79","properties":[{"key":"Description","value":"-"}]},{"database":"InterPro","id":"IPR024264","properties":[{"key":"EntryName","value":"DUF3786"}]},{"database":"Pfam","id":"PF12654","properties":[{"key":"EntryName","value":"DUF3786"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MTSKAPVFEKIYQDYLARVAGLDLTNKQDILGIRVEGQTITIPFFNETFSVFPRKIEDHQGRRPPHSVCVILCQYLLLGPEAPDEDRQLKTYRDFKDAAPYVQGFDNTAQKPVSRAFAGRLAALETGCRHLGGIPGDLGISCDLSYMFEALPRVRIYLIFNDADEDFPADCSLLFEKQAARYLDMECLAMIGMVLAERLAGKDNPDIAMLA","length":211,"molWeight":23629,"crc64":"640AFB96F8F58CCF","md5":"11E2788AE612F73881D5FCC8604A00B6"},"extraAttributes":{"countByFeatureType":{"Domain":1},"uniParcId":"UPI000172D808"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD80","uniProtkbId":"B2DD80_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2025-04-02","lastSequenceUpdateDate":"2008-06-10","entryVersion":28,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28269.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28269.1"}],"value":"Uncharacterized protein"}}]},"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28269.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28269.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28269.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD80","properties":[{"key":"Description","value":"-"}]},{"database":"Gene3D","id":"1.10.10.10","properties":[{"key":"EntryName","value":"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR036388","properties":[{"key":"EntryName","value":"WH-like_DNA-bd_sf"}]},{"database":"InterPro","id":"IPR036390","properties":[{"key":"EntryName","value":"WH_DNA-bd_sf"}]},{"database":"Pfam","id":"PF13412","properties":[{"key":"EntryName","value":"HTH_24"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF46785","properties":[{"key":"EntryName","value":"Winged helix' DNA-binding domain"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MQKKHPIQCQRCKADIPENDEREFNGKVICEDCYMILLSPPKACDPWAAYCAKSFSEKTGSRPDLNPVQVKILQILKETGGISIQELSEQLELPLETFERDIAALRHMEKLRAEMRGGRKIICLWQNND","length":129,"molWeight":14832,"crc64":"EEC23127653143D9","md5":"6D8EEB0A3E6F120D81DE318DB864E869"},"extraAttributes":{"uniParcId":"UPI000172D809"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"B2DD81","uniProtkbId":"B2DD81_9BACT","entryAudit":{"firstPublicDate":"2008-06-10","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2008-06-10","entryVersion":56,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Desulfotignum balticum","taxonId":115781,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28270.1"}],"lineage":["Bacteria","Pseudomonadati","Thermodesulfobacteriota","Desulfobacteria","Desulfobacterales","Desulfobacteraceae","Desulfotignum"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28270.1"}],"value":"Transcriptional regulator"}}]},"features":[{"type":"Domain","location":{"start":{"value":9,"modifier":"EXACT"},"end":{"value":69,"modifier":"EXACT"}},"description":"HTH tetR-type","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50977"}]},{"type":"DNA binding","location":{"start":{"value":32,"modifier":"EXACT"},"end":{"value":51,"modifier":"EXACT"}},"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00335"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023125"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00335"}],"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023163"}],"id":"KW-0804","category":"Biological process","name":"Transcription"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023015"}],"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"18324396","citationType":"journal article","authors":["Habe H.","Kobuna A.","Hosoda A.","Kouzuma A.","Yamane H.","Nojiri H.","Omori T.","Watanabe K."],"citationCrossReferences":[{"database":"PubMed","id":"18324396"},{"database":"DOI","id":"10.1007/s00253-008-1414-5"}],"title":"Subtractive hybridization and random arbitrarily primed PCR analyses of a benzoate-assimilating bacterium, Desulfotignum balticum.","publicationDate":"2008","journal":"Appl. Microbiol. Biotechnol.","firstPage":"87","lastPage":"95","volume":"79"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28270.1"}],"value":"DSM 7044","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAG28270.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB368180","properties":[{"key":"ProteinId","value":"BAG28270.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"B2DD81","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0003700","properties":[{"key":"GoTerm","value":"F:DNA-binding transcription factor activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0000976","properties":[{"key":"GoTerm","value":"F:transcription cis-regulatory region binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"FunFam","id":"1.10.10.60:FF:000141","properties":[{"key":"EntryName","value":"TetR family transcriptional regulator"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.10.60","properties":[{"key":"EntryName","value":"Homeodomain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.357.10","properties":[{"key":"EntryName","value":"Tetracycline Repressor, domain 2"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR009057","properties":[{"key":"EntryName","value":"Homeodomain-like_sf"}]},{"database":"InterPro","id":"IPR050109","properties":[{"key":"EntryName","value":"HTH-type_TetR-like_transc_reg"}]},{"database":"InterPro","id":"IPR001647","properties":[{"key":"EntryName","value":"HTH_TetR"}]},{"database":"InterPro","id":"IPR015893","properties":[{"key":"EntryName","value":"Tet_transcr_reg_TetR-like_C"}]},{"database":"InterPro","id":"IPR039536","properties":[{"key":"EntryName","value":"TetR_C_Proteobacteria"}]},{"database":"PANTHER","id":"PTHR30055:SF146","properties":[{"key":"EntryName","value":"HTH-TYPE TRANSCRIPTIONAL DUAL REGULATOR CECR"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30055","properties":[{"key":"EntryName","value":"HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF14246","properties":[{"key":"EntryName","value":"TetR_C_7"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00440","properties":[{"key":"EntryName","value":"TetR_N"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00455","properties":[{"key":"EntryName","value":"HTHTETR"}]},{"database":"SUPFAM","id":"SSF46689","properties":[{"key":"EntryName","value":"Homeodomain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50977","properties":[{"key":"EntryName","value":"HTH_TETR_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKKLAQNKKHKIENILKAALELFQSNGFINTSMDKIAEEAHVTKQTIYRYFESKESLFRAALEAQQLEGSSDFLKPLTLEDPTQALETFAVGFIERHLSEEHLANIRLLVSEGPKVPEITRAFYAMGPRRTKTCLARFFKDRFNIDNAEDEINIFLAILLSMRMPVLIGLHASPPREKIHRHAMKAVKILMKLLDIERTGEI","length":202,"molWeight":23177,"crc64":"EEAB35BA03E970B8","md5":"C8D1F8D4B9203A7D40EE39E7C3A87DA3"},"extraAttributes":{"countByFeatureType":{"Domain":1,"DNA binding":1},"uniParcId":"UPI000172D80A"}}]}