{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A7YG92","uniProtkbId":"A7YG92_BATDE","entryAudit":{"firstPublicDate":"2007-10-23","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2007-10-23","entryVersion":43,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35072.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012543"}],"value":"chitin synthase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012543"}],"value":"2.4.1.16"}]},"flag":"Fragment"},"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004141"}],"value":"Membrane","id":"SL-0162"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004141"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]}],"features":[{"type":"Transmembrane","location":{"start":{"value":72,"modifier":"EXACT"},"end":{"value":98,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":546,"modifier":"EXACT"},"end":{"value":564,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":571,"modifier":"EXACT"},"end":{"value":594,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Region","location":{"start":{"value":640,"modifier":"EXACT"},"end":{"value":662,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":640,"modifier":"EXACT"},"end":{"value":656,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35072.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":700,"modifier":"EXACT"},"end":{"value":700,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35072.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022676"}],"id":"KW-0328","category":"Molecular function","name":"Glycosyltransferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022676"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-7E8MVRNJR3BMC","citationType":"submission","authors":["Berbee M."],"title":"ESTs from Batrachochytrium dendrobatidis.","publicationDate":"AUG-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35072.1"}],"value":"JEL197","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35072.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ904450","properties":[{"key":"ProteinId","value":"ABK35072.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A7YG92","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0071944","properties":[{"key":"GoTerm","value":"C:cell periphery"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0030428","properties":[{"key":"GoTerm","value":"C:cell septum"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0004100","properties":[{"key":"GoTerm","value":"F:chitin synthase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0006031","properties":[{"key":"GoTerm","value":"P:chitin biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd04190","properties":[{"key":"EntryName","value":"Chitin_synth_C"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR004835","properties":[{"key":"EntryName","value":"Chitin_synth"}]},{"database":"InterPro","id":"IPR029044","properties":[{"key":"EntryName","value":"Nucleotide-diphossugar_trans"}]},{"database":"PANTHER","id":"PTHR22914","properties":[{"key":"EntryName","value":"CHITIN SYNTHASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR22914:SF41","properties":[{"key":"EntryName","value":"CHITIN SYNTHASE 7"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03142","properties":[{"key":"EntryName","value":"Chitin_synth_2"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF53448","properties":[{"key":"EntryName","value":"Nucleotide-diphospho-sugar transferases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"GTRLAPYFEANPEPIAGDVMDTLLRQAQATNDGTHLIWTNKNVSKDMINCLVQKYYAGVLSQLPMSCILSRLVTIVVSFTVVSILVTRFAMALFFDWFMTSHLIRFPKNAPDNPYDPSIAKKYDVKPVLNLRMSDESLMNANNDHASYMKPISQIGTIVRLQDPTIHRPAPNPSDLYTVMFVTCYSEGESALRTTLDSLALTDYDDCKKILFVVADGIVKGSDNQISTPDILISMMHHDEAFGNSPEAFSYVSIATGTKQHNMARVYCGSYSVHGRHIPMVLIIKCGTEYEAGQSKPGNRGKRDSQMILMNFFSRIVLYDRMTPLDYDIFRKIHYLTGVTPDVYELVLMVDADTRVAPDSLRFMVNTMHNEPRIMGLCGETRIANKKDSWVTMIQVFEYFISHHLGKAFESVFGGVTCLPGCFCMYRLKTVKDGSVLPVLVNPDIMNNTHERSITLHQKNLMLLGEDRFLSTLMLRTFPKRLMMFVPAAYCKTTVPDKFSVLLSQRRRWINSTVHNLMELVFVNNLCGTFCFSMQFVVFMDLLGTAVLPASLVCTYYLIVYAILHHGYNNITAFLNLFVMVITMFLPMLLVLLTGRRAHYVLWMLVYLLALPIWHIVLPVYSFWHFDDFSWGETRKVTGDEPKVSSAGTRHDDEQSHGLFDGSRIPFRRWDEYEREARFEQRKHILSMSEPYSQPTQTQS","length":700,"molWeight":79942,"crc64":"4B2E9458C66F1590","md5":"D474E97BB045E11B91715E431E5588DB"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Transmembrane":3,"Region":1,"Compositional bias":1,"Non-terminal residue":2},"uniParcId":"UPI00015C0C1E"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A7YHA6","uniProtkbId":"A7YHA6_BATDE","entryAudit":{"firstPublicDate":"2007-10-23","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2007-10-23","entryVersion":43,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58012.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00024056"}],"value":"chitin deacetylase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00024056"}],"value":"3.5.1.41"}]},"flag":"Fragment"},"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"[(1->4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:10464"},{"database":"Rhea","id":"RHEA-COMP:9593"},{"database":"Rhea","id":"RHEA-COMP:9597"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:17029"},{"database":"ChEBI","id":"CHEBI:30089"},{"database":"ChEBI","id":"CHEBI:57704"}],"ecNumber":"3.5.1.41","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048494"}]},"physiologicalReactions":[{"directionType":"left-to-right","reactionCrossReference":{"database":"Rhea","id":"RHEA:10465"},"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048494"}]}]},{"commentType":"COFACTOR","cofactors":[{"name":"Co(2+)","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001941"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:48828"}}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004609"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004609"}],"value":"Lipid-anchor, GPI-anchor","id":"SL-9902"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004191"}],"value":"Secreted, cell wall","id":"SL-0041"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00010973"}],"value":"Belongs to the polysaccharide deacetylase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":32,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":33,"modifier":"EXACT"},"end":{"value":370,"modifier":"EXACT"}},"description":"chitin deacetylase","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5002718177"},{"type":"Domain","location":{"start":{"value":82,"modifier":"EXACT"},"end":{"value":265,"modifier":"EXACT"}},"description":"NodB homology","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51677"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58012.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":370,"modifier":"EXACT"},"end":{"value":370,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58012.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023277"}],"id":"KW-0119","category":"Biological process","name":"Carbohydrate metabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022512"}],"id":"KW-0134","category":"Cellular component","name":"Cell wall"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023316"}],"id":"KW-0961","category":"Biological process","name":"Cell wall biogenesis/degradation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023024"}],"id":"KW-0146","category":"Biological process","name":"Chitin degradation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023285"}],"id":"KW-0170","category":"Ligand","name":"Cobalt"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023180"}],"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022622"}],"id":"KW-0336","category":"PTM","name":"GPI-anchor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022801"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023288"}],"id":"KW-0449","category":"PTM","name":"Lipoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023326"}],"id":"KW-0624","category":"Biological process","name":"Polysaccharide degradation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022525"}],"id":"KW-0964","category":"Cellular component","name":"Secreted"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-A3UCEJ4P3NKCM","citationType":"submission","authors":["Berbee M.","James T.","Vilgalys R."],"title":"Fungal specific genes in an EST library from Batrachochytrium dendrobatidis.","publicationDate":"AUG-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58012.1"}],"value":"JEL197","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58012.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ911468","properties":[{"key":"ProteinId","value":"ABK58012.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A7YHA6","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0004099","properties":[{"key":"GoTerm","value":"F:chitin deacetylase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0005975","properties":[{"key":"GoTerm","value":"P:carbohydrate metabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006032","properties":[{"key":"GoTerm","value":"P:chitin catabolic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0009272","properties":[{"key":"GoTerm","value":"P:fungal-type cell wall biogenesis"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"CDD","id":"cd10952","properties":[{"key":"EntryName","value":"CE4_MrCDA_like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.20.20.370:FF:000004","properties":[{"key":"EntryName","value":"Related to Chitin deacetylase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.20.20.370","properties":[{"key":"EntryName","value":"Glycoside hydrolase/deacetylase"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR011330","properties":[{"key":"EntryName","value":"Glyco_hydro/deAcase_b/a-brl"}]},{"database":"InterPro","id":"IPR002509","properties":[{"key":"EntryName","value":"NODB_dom"}]},{"database":"InterPro","id":"IPR050248","properties":[{"key":"EntryName","value":"Polysacc_deacetylase_ArnD"}]},{"database":"PANTHER","id":"PTHR10587:SF133","properties":[{"key":"EntryName","value":"CHITIN DEACETYLASE 1-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10587","properties":[{"key":"EntryName","value":"GLYCOSYL TRANSFERASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01522","properties":[{"key":"EntryName","value":"Polysacc_deac_1"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF88713","properties":[{"key":"EntryName","value":"Glycoside hydrolase/deacetylase"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51677","properties":[{"key":"EntryName","value":"NODB"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"RHEGRMVFSVSTIIYLSLLSLELASFKSQVFAGTPDPANYPKLEVAPPSYEPWNKRFLGGDLPPHGTEANLWRDQIQCRNSHSWALTYDDGPSEFTPRVLNALGEHNFKATFFVIGSMVVRNPKYIQDVYAAGHEIGIHTWSHPQMTQISDEQIVAEIYWTVKAIQEAIGVVPKLFRPPYGDIDERVRTILKRMGLTIINWNQDSGDALGATDVVERFKHWSSTGHPGGILSLEHDRFNASSAQAVPAMSIVAASTYKTVKMSECIGQTKIYDSELMTGNGHVAPFFESTSPSVIVSVSASINASATMTQTAAMSSSQVPAKLSSTTESLAGLPAATNPSKNDALTSCKSWSLSAMMILFATCAELVYGW","length":370,"molWeight":40468,"crc64":"82D14A484552E67A","md5":"444E640E0C2AF59CBD6FF8DD94DA2E3E"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"COFACTOR":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Signal":1,"Chain":1,"Domain":1,"Non-terminal residue":2},"uniParcId":"UPI00015C0D07"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A7YHA8","uniProtkbId":"A7YHA8_BATDE","entryAudit":{"firstPublicDate":"2007-10-23","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2007-10-23","entryVersion":47,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58013.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00024056"}],"value":"chitin deacetylase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00024056"}],"value":"3.5.1.41"}]},"flag":"Fragment"},"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"[(1->4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:10464"},{"database":"Rhea","id":"RHEA-COMP:9593"},{"database":"Rhea","id":"RHEA-COMP:9597"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:17029"},{"database":"ChEBI","id":"CHEBI:30089"},{"database":"ChEBI","id":"CHEBI:57704"}],"ecNumber":"3.5.1.41","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048494"}]},"physiologicalReactions":[{"directionType":"left-to-right","reactionCrossReference":{"database":"Rhea","id":"RHEA:10465"},"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00048494"}]}]},{"commentType":"COFACTOR","cofactors":[{"name":"Co(2+)","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001941"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:48828"}}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004609"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004609"}],"value":"Lipid-anchor, GPI-anchor","id":"SL-9902"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004191"}],"value":"Secreted, cell wall","id":"SL-0041"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00010973"}],"value":"Belongs to the polysaccharide deacetylase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":16,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":17,"modifier":"EXACT"},"end":{"value":334,"modifier":"EXACT"}},"description":"chitin deacetylase","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5052648158"},{"type":"Domain","location":{"start":{"value":70,"modifier":"EXACT"},"end":{"value":252,"modifier":"EXACT"}},"description":"NodB homology","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51677"}]},{"type":"Region","location":{"start":{"value":279,"modifier":"EXACT"},"end":{"value":304,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":280,"modifier":"EXACT"},"end":{"value":303,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58013.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":334,"modifier":"EXACT"},"end":{"value":334,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58013.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023277"}],"id":"KW-0119","category":"Biological process","name":"Carbohydrate metabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022512"}],"id":"KW-0134","category":"Cellular component","name":"Cell wall"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023316"}],"id":"KW-0961","category":"Biological process","name":"Cell wall biogenesis/degradation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023024"}],"id":"KW-0146","category":"Biological process","name":"Chitin degradation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023285"}],"id":"KW-0170","category":"Ligand","name":"Cobalt"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023180"}],"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022622"}],"id":"KW-0336","category":"PTM","name":"GPI-anchor"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022801"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023288"}],"id":"KW-0449","category":"PTM","name":"Lipoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023326"}],"id":"KW-0624","category":"Biological process","name":"Polysaccharide degradation"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022525"}],"id":"KW-0964","category":"Cellular component","name":"Secreted"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-A3UCEJ4P3NKCM","citationType":"submission","authors":["Berbee M.","James T.","Vilgalys R."],"title":"Fungal specific genes in an EST library from Batrachochytrium dendrobatidis.","publicationDate":"AUG-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58013.1"}],"value":"JEL197","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58013.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ911469","properties":[{"key":"ProteinId","value":"ABK58013.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A7YHA8","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0004099","properties":[{"key":"GoTerm","value":"F:chitin deacetylase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0005975","properties":[{"key":"GoTerm","value":"P:carbohydrate metabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006032","properties":[{"key":"GoTerm","value":"P:chitin catabolic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0009272","properties":[{"key":"GoTerm","value":"P:fungal-type cell wall biogenesis"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"FunFam","id":"3.20.20.370:FF:000004","properties":[{"key":"EntryName","value":"Related to Chitin deacetylase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.20.20.370","properties":[{"key":"EntryName","value":"Glycoside hydrolase/deacetylase"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR011330","properties":[{"key":"EntryName","value":"Glyco_hydro/deAcase_b/a-brl"}]},{"database":"InterPro","id":"IPR002509","properties":[{"key":"EntryName","value":"NODB_dom"}]},{"database":"InterPro","id":"IPR050248","properties":[{"key":"EntryName","value":"Polysacc_deacetylase_ArnD"}]},{"database":"PANTHER","id":"PTHR10587:SF133","properties":[{"key":"EntryName","value":"CHITIN DEACETYLASE 1-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10587","properties":[{"key":"EntryName","value":"GLYCOSYL TRANSFERASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01522","properties":[{"key":"EntryName","value":"Polysacc_deac_1"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF88713","properties":[{"key":"EntryName","value":"Glycoside hydrolase/deacetylase"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51677","properties":[{"key":"EntryName","value":"NODB"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"TASFVFLTLSSAINAAVPIATDYPAPDVLAPANATWSNTILKDIPNIPVNALGLPTPNWSADIVTCPSANMWGLSYDDGPGPYTDNLLSVLAAKKVKATFFIVGSRVLQYSDVLLRTYQAGHHIALHTWSHRNSTAVTNEQFVAEIIYNARIIKDVIGVTPRFFRPPFGDIDERIRKILHNLGLIIVEWNVDSADAAGAKDVAVKFGAKANAGSSPVISLEHDLFATTEPQAGPALDAILAGTGKYKPMPIDECLGYAAYDEGFWDRVAGKGLPPINLVSGSSPSTNSTSTSSTGSAGSTTGSHKSFSLRSVESAWTVMTIVGTVALVGGIFIF","length":334,"molWeight":35394,"crc64":"F9BC43B29C333A18","md5":"026CCA5598643C1934EB9D87569410B8"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"COFACTOR":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Signal":1,"Chain":1,"Domain":1,"Region":1,"Compositional bias":1,"Non-terminal residue":2},"uniParcId":"UPI00015C0D08"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A7YHB2","uniProtkbId":"A7YHB2_BATDE","entryAudit":{"firstPublicDate":"2007-10-23","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2007-10-23","entryVersion":60,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58015.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58015.1"}],"value":"Putative chitin deacetylase"}}],"flag":"Fragment"},"comments":[{"commentType":"COFACTOR","cofactors":[{"name":"Co(2+)","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00001941"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:48828"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":20,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":21,"modifier":"EXACT"},"end":{"value":242,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5002715730"},{"type":"Domain","location":{"start":{"value":28,"modifier":"EXACT"},"end":{"value":70,"modifier":"EXACT"}},"description":"Chitin-binding type-1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50941"}]},{"type":"Domain","location":{"start":{"value":92,"modifier":"EXACT"},"end":{"value":135,"modifier":"EXACT"}},"description":"Chitin-binding type-1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50941"}]},{"type":"Domain","location":{"start":{"value":172,"modifier":"EXACT"},"end":{"value":242,"modifier":"EXACT"}},"description":"NodB homology","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51677"}]},{"type":"Region","location":{"start":{"value":71,"modifier":"EXACT"},"end":{"value":92,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":137,"modifier":"EXACT"},"end":{"value":157,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":137,"modifier":"EXACT"},"end":{"value":153,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Disulfide bond","location":{"start":{"value":38,"modifier":"EXACT"},"end":{"value":50,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":43,"modifier":"EXACT"},"end":{"value":57,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":103,"modifier":"EXACT"},"end":{"value":115,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":108,"modifier":"EXACT"},"end":{"value":122,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58015.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":242,"modifier":"EXACT"},"end":{"value":242,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58015.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023277"}],"id":"KW-0119","category":"Biological process","name":"Carbohydrate metabolism"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022669"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}],"id":"KW-0147","category":"Ligand","name":"Chitin-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023285"}],"id":"KW-0170","category":"Ligand","name":"Cobalt"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}],"id":"KW-1015","category":"PTM","name":"Disulfide bond"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022801"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-A3UCEJ4P3NKCM","citationType":"submission","authors":["Berbee M.","James T.","Vilgalys R."],"title":"Fungal specific genes in an EST library from Batrachochytrium dendrobatidis.","publicationDate":"AUG-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58015.1"}],"value":"JEL197","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58015.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ911471","properties":[{"key":"ProteinId","value":"ABK58015.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A7YHB2","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0008061","properties":[{"key":"GoTerm","value":"F:chitin binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"GO","id":"GO:0016810","properties":[{"key":"GoTerm","value":"F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0005975","properties":[{"key":"GoTerm","value":"P:carbohydrate metabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd11618","properties":[{"key":"EntryName","value":"ChtBD1_1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.60.10","properties":[{"key":"EntryName","value":"Endochitinase-like"},{"key":"MatchStatus","value":"2"}]},{"database":"Gene3D","id":"3.20.20.370","properties":[{"key":"EntryName","value":"Glycoside hydrolase/deacetylase"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR001002","properties":[{"key":"EntryName","value":"Chitin-bd_1"}]},{"database":"InterPro","id":"IPR036861","properties":[{"key":"EntryName","value":"Endochitinase-like_sf"}]},{"database":"InterPro","id":"IPR011330","properties":[{"key":"EntryName","value":"Glyco_hydro/deAcase_b/a-brl"}]},{"database":"InterPro","id":"IPR002509","properties":[{"key":"EntryName","value":"NODB_dom"}]},{"database":"PANTHER","id":"PTHR46471","properties":[{"key":"EntryName","value":"CHITIN DEACETYLASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR46471:SF2","properties":[{"key":"EntryName","value":"CHITIN DEACETYLASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00187","properties":[{"key":"EntryName","value":"Chitin_bind_1"},{"key":"MatchStatus","value":"2"}]},{"database":"Pfam","id":"PF01522","properties":[{"key":"EntryName","value":"Polysacc_deac_1"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00270","properties":[{"key":"EntryName","value":"ChtBD1"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF88713","properties":[{"key":"EntryName","value":"Glycoside hydrolase/deacetylase"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF57016","properties":[{"key":"EntryName","value":"Plant lectins/antimicrobial peptides"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS50941","properties":[{"key":"EntryName","value":"CHIT_BIND_I_2"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS51677","properties":[{"key":"EntryName","value":"NODB"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"RHEALTQIILTALFVRLSAAIPAATGDDPTCGPGLGRCDPGECCSQYGYCDVTPAHCGVGCQPAFGVCKNTPTSTSRPKPSPTPKKLPESPDSTCGQAAGYRCAQGDCCSQYNFCGNTAAHCGAGCQSAFGTCKSPTRSSSKGGPTPAPTSSFPIPDPKLSAPVITTCKSPKQFALTFDDGPTSNVSAILDMLKDNNVKATFFVNGNNFADLTVEPYISILRRAHTEGHQIASHTLTHPRYD","length":242,"molWeight":25349,"crc64":"B268CAC86C050F9E","md5":"13571526F1D8515B81553676DC31E566"},"extraAttributes":{"countByCommentType":{"COFACTOR":1,"CAUTION":1},"countByFeatureType":{"Signal":1,"Chain":1,"Domain":3,"Region":2,"Compositional bias":1,"Disulfide bond":4,"Non-terminal residue":2},"uniParcId":"UPI00015C0D0A"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"W0TGZ1","uniProtkbId":"W0TGZ1_BATDE","entryAudit":{"firstPublicDate":"2014-03-19","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2014-03-19","entryVersion":34,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42882.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42882.1"}],"value":"Indoleamine 2,3-dioxygenase"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42882.1"}],"value":"IDO"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00007119"}],"value":"Belongs to the indoleamine 2,3-dioxygenase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Binding site","location":{"start":{"value":394,"modifier":"EXACT"},"end":{"value":394,"modifier":"EXACT"}},"description":"proximal binding residue","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:60344"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600898-1"}],"ligand":{"name":"heme b","id":"ChEBI:CHEBI:60344"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42882.1"}],"id":"KW-0223","category":"Molecular function","name":"Dioxygenase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600898-1"}],"id":"KW-0349","category":"Ligand","name":"Heme"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600898-1"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600898-1"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42882.1"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-FCVN2K6ALQ85J","citationType":"submission","authors":["Yuasa H.","Okada Y."],"title":"cDNA sequences of indoleamine 2,3-dioxygenases of Rhizopus delemar and Batrachochytrium dendrobatidis.","publicationDate":"JAN-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42882.1"}],"value":"NBRC 106979","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42882.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB902915","properties":[{"key":"ProteinId","value":"BAO42882.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"W0TGZ1","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"AAFNQCV","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0020037","properties":[{"key":"GoTerm","value":"F:heme binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0033754","properties":[{"key":"GoTerm","value":"F:indoleamine 2,3-dioxygenase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0046872","properties":[{"key":"GoTerm","value":"F:metal ion binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0034354","properties":[{"key":"GoTerm","value":"P:'de novo' NAD+ biosynthetic process from L-tryptophan"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0006569","properties":[{"key":"GoTerm","value":"P:L-tryptophan catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"1.20.58.480","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR000898","properties":[{"key":"EntryName","value":"Indolamine_dOase"}]},{"database":"InterPro","id":"IPR037217","properties":[{"key":"EntryName","value":"Trp/Indoleamine_2_3_dOase-like"}]},{"database":"PANTHER","id":"PTHR28657","properties":[{"key":"EntryName","value":"INDOLEAMINE 2,3-DIOXYGENASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR28657:SF5","properties":[{"key":"EntryName","value":"INDOLEAMINE 2,3-DIOXYGENASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01231","properties":[{"key":"EntryName","value":"IDO"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF140959","properties":[{"key":"EntryName","value":"Indolic compounds 2,3-dioxygenase-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSPFLTNIGQCVPRLEDYDIDPVNGFLSSPPLKRLPALFHPWEHIMDHLHQLMISSSLRSWVLRLPLLDVNQLETKREWQRAHLVLTFIAHSYIIGLPKIDKVESVLPESVAVPWITVSKKLLVKPVMSYYAVELSNWYKLDSDGPLDLSNIAISHTFTGTVDEAWFYLVPLAIEAAGAPAIKGLVDAQQAILDKDHTALVSALYTISNATEGLTALLKRMYEKCDADIFFNRFRHYSRGSKNSQDVPNGVFYQGVTEMDEFVNLETPNPKGLIGTWRKYAGASAGQSPLIHTLDVGLDIHHVPMHGTLNESNPSFSTDSKSSLPARFPSKPHYVNPMLEMRESLSQDHQNFLRALGNGPSIRAHIASLSGDDNTAVVQFNRAVDNIKQFRDAHISLTAMYIVLQAKKAAAAAGESSSRVCVGTGGTDLVPFLKQTRDETVNALILLP","length":448,"molWeight":49647,"crc64":"6A4E6B0FABA4C60C","md5":"2C0EB64A5D1D4E3C32FD7D7263B1C9E5"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Binding site":1},"uniParcId":"UPI00020FAF8E"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A097F7X9","uniProtkbId":"A0A097F7X9_BATDE","entryAudit":{"firstPublicDate":"2015-01-07","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2015-01-07","entryVersion":32,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIT18659.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIT18659.1"}],"value":"Lectin-like protein"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIT18659.1"}],"value":"CBM18-LL1"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}],"value":"Lacks conserved residue(s) required for the propagation of feature annotation"}],"commentType":"CAUTION"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":19,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":20,"modifier":"EXACT"},"end":{"value":465,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5001934568"},{"type":"Domain","location":{"start":{"value":30,"modifier":"EXACT"},"end":{"value":73,"modifier":"EXACT"}},"description":"Chitin-binding type-1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50941"}]},{"type":"Domain","location":{"start":{"value":88,"modifier":"EXACT"},"end":{"value":131,"modifier":"EXACT"}},"description":"Chitin-binding type-1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50941"}]},{"type":"Domain","location":{"start":{"value":147,"modifier":"EXACT"},"end":{"value":190,"modifier":"EXACT"}},"description":"Chitin-binding type-1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50941"}]},{"type":"Domain","location":{"start":{"value":213,"modifier":"EXACT"},"end":{"value":256,"modifier":"EXACT"}},"description":"Chitin-binding type-1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50941"}]},{"type":"Domain","location":{"start":{"value":279,"modifier":"EXACT"},"end":{"value":322,"modifier":"EXACT"}},"description":"Chitin-binding type-1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50941"}]},{"type":"Domain","location":{"start":{"value":345,"modifier":"EXACT"},"end":{"value":388,"modifier":"EXACT"}},"description":"Chitin-binding type-1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50941"}]},{"type":"Domain","location":{"start":{"value":411,"modifier":"EXACT"},"end":{"value":454,"modifier":"EXACT"}},"description":"Chitin-binding type-1","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50941"}]},{"type":"Disulfide bond","location":{"start":{"value":41,"modifier":"EXACT"},"end":{"value":53,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":46,"modifier":"EXACT"},"end":{"value":60,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":99,"modifier":"EXACT"},"end":{"value":111,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":104,"modifier":"EXACT"},"end":{"value":118,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":158,"modifier":"EXACT"},"end":{"value":170,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":163,"modifier":"EXACT"},"end":{"value":177,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":224,"modifier":"EXACT"},"end":{"value":236,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":229,"modifier":"EXACT"},"end":{"value":243,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":290,"modifier":"EXACT"},"end":{"value":302,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":295,"modifier":"EXACT"},"end":{"value":309,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":356,"modifier":"EXACT"},"end":{"value":368,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":361,"modifier":"EXACT"},"end":{"value":375,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":422,"modifier":"EXACT"},"end":{"value":434,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]},{"type":"Disulfide bond","location":{"start":{"value":427,"modifier":"EXACT"},"end":{"value":441,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022669"},{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}],"id":"KW-0147","category":"Ligand","name":"Chitin-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PROSITE-ProRule","id":"PRU00261"}],"id":"KW-1015","category":"PTM","name":"Disulfide bond"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022801"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-DGO619CTRRVN9","citationType":"submission","authors":["Stajich J.E.","Liu P."],"title":"Characterization of CBM18 gene family in the amphibian pathogen Batrachochytrium dendrobatidis role in chitin binding and chitinase protection.","publicationDate":"JUL-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIT18659.1"}],"value":"JEL423","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AIT18659.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KM099424","properties":[{"key":"ProteinId","value":"AIT18659.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A0A097F7X9","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A0A097F7X9","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0008061","properties":[{"key":"GoTerm","value":"F:chitin binding"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"CDD","id":"cd00035","properties":[{"key":"EntryName","value":"ChtBD1"},{"key":"MatchStatus","value":"5"}]},{"database":"Gene3D","id":"3.30.60.10","properties":[{"key":"EntryName","value":"Endochitinase-like"},{"key":"MatchStatus","value":"7"}]},{"database":"InterPro","id":"IPR001002","properties":[{"key":"EntryName","value":"Chitin-bd_1"}]},{"database":"InterPro","id":"IPR018371","properties":[{"key":"EntryName","value":"Chitin-binding_1_CS"}]},{"database":"InterPro","id":"IPR036861","properties":[{"key":"EntryName","value":"Endochitinase-like_sf"}]},{"database":"PANTHER","id":"PTHR46471","properties":[{"key":"EntryName","value":"CHITIN DEACETYLASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR46471:SF2","properties":[{"key":"EntryName","value":"CHITIN DEACETYLASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00187","properties":[{"key":"EntryName","value":"Chitin_bind_1"},{"key":"MatchStatus","value":"4"}]},{"database":"SMART","id":"SM00270","properties":[{"key":"EntryName","value":"ChtBD1"},{"key":"MatchStatus","value":"7"}]},{"database":"SUPFAM","id":"SSF57016","properties":[{"key":"EntryName","value":"Plant lectins/antimicrobial peptides"},{"key":"MatchStatus","value":"7"}]},{"database":"PROSITE","id":"PS00026","properties":[{"key":"EntryName","value":"CHIT_BIND_I_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50941","properties":[{"key":"EntryName","value":"CHIT_BIND_I_2"},{"key":"MatchStatus","value":"7"}]}],"sequence":{"value":"MVVIIHAVLIAALATVVFGQPGMSFTVSTNGRCGKKLGTTCPGNSCCSQNNMCGHSDSDCGDGCQIGYGLCSEIRSSITLSSKVTIYDGQCGPEFKIKCFKNRCCSKKGYCGLGSYYCQAGCKKGYGDCWGTNTPSILNSNFVYNPSNSCGPDVNIRCGDKKCCSIGGVCGSSNYHCGVGCQGRYGSCSKAGTSTDLISVLPKSNIKHPISKNNRCGKKFGTRCPGQKCCSGKGFCGKTPSHCGKNCQKDFGPCSKAETSTELISVLPKSSIRHLISKNNRCGKKFGTRCPGQKCCSGKGFCGKTPSHCGKNCQKDFGSCSKAGTSTDLISVLPKSSIRHLISKNNRCGKKFGTRCPGQKCCSGKGFCGKTPSHCGKNCQKDFGSCSKAETSTELISVLPKSNIKHPISKNNRCGKKFGTRCPGQKCCSGKGFCGKTPSHCGKNCQKSFGSCSKAKTVLKSKAEL","length":465,"molWeight":49022,"crc64":"21FC22ED85D5A3C8","md5":"16C507596A63A95F121F15F9626DB889"},"extraAttributes":{"countByCommentType":{"CAUTION":1},"countByFeatureType":{"Signal":1,"Chain":1,"Domain":7,"Disulfide bond":14},"uniParcId":"UPI00051CAEC8"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A7YG86","uniProtkbId":"A7YG86_BATDE","entryAudit":{"firstPublicDate":"2007-10-23","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2007-10-23","entryVersion":32,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35069.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35069.1"}],"value":"Putative chitin synthase division I"}}],"flag":"Fragment"},"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004141"}],"value":"Membrane","id":"SL-0162"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004141"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]}],"features":[{"type":"Transmembrane","location":{"start":{"value":6,"modifier":"EXACT"},"end":{"value":25,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":136,"modifier":"EXACT"},"end":{"value":156,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":176,"modifier":"EXACT"},"end":{"value":203,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35069.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":220,"modifier":"EXACT"},"end":{"value":220,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35069.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-7E8MVRNJR3BMC","citationType":"submission","authors":["Berbee M."],"title":"ESTs from Batrachochytrium dendrobatidis.","publicationDate":"AUG-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35069.1"}],"value":"JEL197","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35069.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ904447","properties":[{"key":"ProteinId","value":"ABK35069.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A7YG86","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0071944","properties":[{"key":"GoTerm","value":"C:cell periphery"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0030428","properties":[{"key":"GoTerm","value":"C:cell septum"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0004100","properties":[{"key":"GoTerm","value":"F:chitin synthase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006031","properties":[{"key":"GoTerm","value":"P:chitin biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"InterPro","id":"IPR004835","properties":[{"key":"EntryName","value":"Chitin_synth"}]},{"database":"PANTHER","id":"PTHR22914","properties":[{"key":"EntryName","value":"CHITIN SYNTHASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR22914:SF44","properties":[{"key":"EntryName","value":"CHITIN SYNTHASE 2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03142","properties":[{"key":"EntryName","value":"Chitin_synth_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"TVFRDLVVSIMSTYGLYFVASIIHLDPWHCITSMIQYLLILPTYNNIFMIYAFCNLHDVSWGTKGDNAVVDDKPAVVQKTANGEQVFEVEIPSEEQDIDAAWAAHIKQLASNRANPEVQNSKRDVKTKSEDVCKEFRTRVVLSWIITNSLIIALFTNDAFINHVFKPSPENSVNPYLTFIFWSVAVLSAIRFIGCCVYMVIWWGEKLSGAARGGSRKVHA","length":220,"molWeight":24852,"crc64":"B7F090EE0C796071","md5":"5D20682EDEA284EBC1D8040B5A31437C"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Transmembrane":3,"Non-terminal residue":2},"uniParcId":"UPI00015C0C1B"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A7YG89","uniProtkbId":"A7YG89_BATDE","entryAudit":{"firstPublicDate":"2007-10-23","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2007-10-23","entryVersion":50,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35070.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012543"}],"value":"chitin synthase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00012543"}],"value":"2.4.1.16"}]},"flag":"Fragment"},"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004651"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004651"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]}],"features":[{"type":"Domain","location":{"start":{"value":532,"modifier":"EXACT"},"end":{"value":587,"modifier":"EXACT"}},"description":"DEK-C","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51998"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35070.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":590,"modifier":"EXACT"},"end":{"value":590,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35070.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023180"}],"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022676"}],"id":"KW-0328","category":"Molecular function","name":"Glycosyltransferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022989"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-7E8MVRNJR3BMC","citationType":"submission","authors":["Berbee M."],"title":"ESTs from Batrachochytrium dendrobatidis.","publicationDate":"AUG-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35070.1"}],"value":"JEL197","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35070.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ904448","properties":[{"key":"ProteinId","value":"ABK35070.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"GO","id":"GO:0030428","properties":[{"key":"GoTerm","value":"C:cell septum"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0004100","properties":[{"key":"GoTerm","value":"F:chitin synthase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0006031","properties":[{"key":"GoTerm","value":"P:chitin biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0031505","properties":[{"key":"GoTerm","value":"P:fungal-type cell wall organization"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd04190","properties":[{"key":"EntryName","value":"Chitin_synth_C"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.10.60","properties":[{"key":"EntryName","value":"Homeodomain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.90.550.10","properties":[{"key":"EntryName","value":"Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR004835","properties":[{"key":"EntryName","value":"Chitin_synth"}]},{"database":"InterPro","id":"IPR014876","properties":[{"key":"EntryName","value":"DEK_C"}]},{"database":"InterPro","id":"IPR029044","properties":[{"key":"EntryName","value":"Nucleotide-diphossugar_trans"}]},{"database":"PANTHER","id":"PTHR22914","properties":[{"key":"EntryName","value":"CHITIN SYNTHASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR22914:SF13","properties":[{"key":"EntryName","value":"CHITIN SYNTHASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03142","properties":[{"key":"EntryName","value":"Chitin_synth_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF08766","properties":[{"key":"EntryName","value":"DEK_C"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF109715","properties":[{"key":"EntryName","value":"DEK C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF53448","properties":[{"key":"EntryName","value":"Nucleotide-diphospho-sugar transferases"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51998","properties":[{"key":"EntryName","value":"DEK_C"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"VKPGNRGKRDSQLVLMRFLNRVHFNAEFAPMELDIYHHMKNIIGVSPSFYEFILMIDADTEVEPNALNRMVSVMVHDVKVMGLCGETRISNEKESWVTMVQVYEYFISHHLSKAFESLFGTVTCLPGCFSMYRIRSASKNVPLLVSPALLTEYSENSVDTLHMKNLLHLGEDRYLTTLMLKHFPTMRTKFAGEARCSTVVPDKWSVLLSQRRRWINSTVHNLFELVFLDQLCGLCCFSMRFVVFLDLFAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRSIPLERWKDFEGSGGAGSVDSRGGVDAWEHGSQASGSIVQAGAHRNKAAGYAGSEYSSPGGGVYHRGSAASNYAGSAYGGPAPSISGSYHGGLPVIAQSTVPARYNTHDLTPGQAADPQRFSMISFGAYPTQTNEMQNARNSSASLVPGPFPSQQTNRYSMLSNTSQQVPVQTGPTDEQILADIRQILSSGDLMTLTKKQIRDDLGQRFGVDLRPRKETINRMIDEVLQGRL","length":590,"molWeight":65509,"crc64":"EF7D994B200EB8C1","md5":"106E2F9E2AEE3C394AF6BFB70D916B40"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Domain":1,"Non-terminal residue":2},"uniParcId":"UPI00015C0C1C"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A7YG90","uniProtkbId":"A7YG90_BATDE","entryAudit":{"firstPublicDate":"2007-10-23","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2007-10-23","entryVersion":48,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35071.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35071.1"}],"value":"Putative chitin synthase division II"}}],"flag":"Fragment"},"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004651"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004651"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]}],"features":[{"type":"Transmembrane","location":{"start":{"value":107,"modifier":"EXACT"},"end":{"value":134,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Transmembrane","location":{"start":{"value":140,"modifier":"EXACT"},"end":{"value":161,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}]},{"type":"Domain","location":{"start":{"value":350,"modifier":"EXACT"},"end":{"value":405,"modifier":"EXACT"}},"description":"DEK-C","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51998"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35071.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":408,"modifier":"EXACT"},"end":{"value":408,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35071.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022475"}],"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023180"}],"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023136"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022679"}],"id":"KW-0808","category":"Molecular function","name":"Transferase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022692"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"Phobius"}],"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-7E8MVRNJR3BMC","citationType":"submission","authors":["Berbee M."],"title":"ESTs from Batrachochytrium dendrobatidis.","publicationDate":"AUG-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35071.1"}],"value":"JEL197","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK35071.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ904449","properties":[{"key":"ProteinId","value":"ABK35071.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A7YG90","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0030428","properties":[{"key":"GoTerm","value":"C:cell septum"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0004100","properties":[{"key":"GoTerm","value":"F:chitin synthase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006031","properties":[{"key":"GoTerm","value":"P:chitin biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0031505","properties":[{"key":"GoTerm","value":"P:fungal-type cell wall organization"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"Gene3D","id":"1.10.10.60","properties":[{"key":"EntryName","value":"Homeodomain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR004835","properties":[{"key":"EntryName","value":"Chitin_synth"}]},{"database":"InterPro","id":"IPR014876","properties":[{"key":"EntryName","value":"DEK_C"}]},{"database":"PANTHER","id":"PTHR22914","properties":[{"key":"EntryName","value":"CHITIN SYNTHASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR22914:SF13","properties":[{"key":"EntryName","value":"CHITIN SYNTHASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03142","properties":[{"key":"EntryName","value":"Chitin_synth_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF08766","properties":[{"key":"EntryName","value":"DEK_C"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF109715","properties":[{"key":"EntryName","value":"DEK C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51998","properties":[{"key":"EntryName","value":"DEK_C"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"RSPTKSVPLLIAPGIVEDYSLNRVDTLHVKNLLQLGEDRYLTTLMMKHFPNLKLSFNPDAQCRTNAPDRWKVLLSQRRRWINSTVHNLIELLSLEQMCGFCCFSMRFVVFLDLFSTVVQPAGVLYIAYLVYSLITSPDVFPTISIVMLAAVYGFQVIIFVLKRQWAQIGWMIVYILATPVFGFYIPIYSFWRFDDFSWGNTRIVLGERGGHAKGSTKEFDPKTIPLKKWADVDYDKWDGQSQVSGGLSSCTGVYPPSNSNSIKKSNRLTLTVPVPGYLKYGDGGMLGSARSPQLNSAGTGSSMPSIRADIKDPLLPQGEPLNRQIPSPLPFAPPAQHAPRYDHQAGNLTVPTDEDIIRELRNVLATVDLMVVTKRHVRDDVSRRLGVDLSSRRSNINMFMDQILHGKL","length":408,"molWeight":45878,"crc64":"D2F94A262B01790D","md5":"72D48FBDC186F9B34B348D1D68F7BB35"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Transmembrane":2,"Domain":1,"Non-terminal residue":2},"uniParcId":"UPI00015C0C1D"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A7YHA4","uniProtkbId":"A7YHA4_BATDE","entryAudit":{"firstPublicDate":"2007-10-23","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2007-10-23","entryVersion":30,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58011.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58011.1"}],"value":"Putative chitin deacetylase"}}],"flag":"Fragment"},"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58011.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":248,"modifier":"EXACT"},"end":{"value":248,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58011.1"}]}],"references":[{"referenceNumber":1,"citation":{"id":"CI-A3UCEJ4P3NKCM","citationType":"submission","authors":["Berbee M.","James T.","Vilgalys R."],"title":"Fungal specific genes in an EST library from Batrachochytrium dendrobatidis.","publicationDate":"AUG-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58011.1"}],"value":"JEL197","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58011.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ911467","properties":[{"key":"ProteinId","value":"ABK58011.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"Gene3D","id":"3.20.20.80","properties":[{"key":"EntryName","value":"Glycosidases"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR052750","properties":[{"key":"EntryName","value":"GH18_Chitinase"}]},{"database":"InterPro","id":"IPR017853","properties":[{"key":"EntryName","value":"GH_hydrolase_sf"}]},{"database":"PANTHER","id":"PTHR42976","properties":[{"key":"EntryName","value":"BIFUNCTIONAL CHITINASE/LYSOZYME-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42976:SF1","properties":[{"key":"EntryName","value":"GH18 DOMAIN-CONTAINING PROTEIN-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF51445","properties":[{"key":"EntryName","value":"(Trans)glycosidases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"RRAQALVQIKKLYPNIKISYTLPVLPSGLTAEGVAILSNAAANGLVIDVVNIMAMDYGSGPAPNGATGMGGYAISAAKATYAQAKPIFPSVTIGVTPMIGVNDVQGEVFRVEDAAQLTQFAQSTSWISLLSFWSINRDHGVIGPLFASSRIQQSKYDFATAMLPFELSASVAKTPVPAPKLPLANIPGLYNWPSTVFAPTIDTTAANAANIVTMATTVGTNMYNLGYIVADANANQVGEXHMVYPSRG","length":248,"molWeight":26092,"crc64":"A88F78C94B94E535","md5":"AA563FDFDB5E01A5E3372AD3ED728FCC"},"extraAttributes":{"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI00015C0D06"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A7YHB0","uniProtkbId":"A7YHB0_BATDE","entryAudit":{"firstPublicDate":"2007-10-23","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2007-10-23","entryVersion":42,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58014.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58014.1"}],"value":"Putative chitin deacetylase"}}],"flag":"Fragment"},"features":[{"type":"Domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":179,"modifier":"EXACT"}},"description":"NodB homology","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS51677"}]},{"type":"Region","location":{"start":{"value":213,"modifier":"EXACT"},"end":{"value":249,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":213,"modifier":"EXACT"},"end":{"value":232,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58014.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":275,"modifier":"EXACT"},"end":{"value":275,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58014.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022801"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-A3UCEJ4P3NKCM","citationType":"submission","authors":["Berbee M.","James T.","Vilgalys R."],"title":"Fungal specific genes in an EST library from Batrachochytrium dendrobatidis.","publicationDate":"AUG-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58014.1"}],"value":"JEL197","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ABK58014.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ911470","properties":[{"key":"ProteinId","value":"ABK58014.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"A7YHB0","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"AVDMGTC","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0004099","properties":[{"key":"GoTerm","value":"F:chitin deacetylase activity"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0005975","properties":[{"key":"GoTerm","value":"P:carbohydrate metabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009272","properties":[{"key":"GoTerm","value":"P:fungal-type cell wall biogenesis"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"Gene3D","id":"3.20.20.370","properties":[{"key":"EntryName","value":"Glycoside hydrolase/deacetylase"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR011330","properties":[{"key":"EntryName","value":"Glyco_hydro/deAcase_b/a-brl"}]},{"database":"InterPro","id":"IPR002509","properties":[{"key":"EntryName","value":"NODB_dom"}]},{"database":"InterPro","id":"IPR050248","properties":[{"key":"EntryName","value":"Polysacc_deacetylase_ArnD"}]},{"database":"PANTHER","id":"PTHR10587:SF133","properties":[{"key":"EntryName","value":"CHITIN DEACETYLASE 1-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10587","properties":[{"key":"EntryName","value":"GLYCOSYL TRANSFERASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01522","properties":[{"key":"EntryName","value":"Polysacc_deac_1"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF88713","properties":[{"key":"EntryName","value":"Glycoside hydrolase/deacetylase"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51677","properties":[{"key":"EntryName","value":"NODB"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"LSFNFKLRILSSAFTPALLDELKRRNVKTTFFVVGSRVLENPAILQRAYAEGHQIAIHTWSHPAMTTVTNEQLVAEIMFTAHIIKGVIGVTPRMLRPPYGDIDERVRALIHLMKMDIIVWAFDSGDSAGSMDVVNAMTAEANILPKTGPITLEHDLTSAEASQGPGAIDGVLAAGYKIVRMDECLGNPAYDETIWSSFPADGILAPLNANTPATKSATNSATKPTPLSSTTLGHGVNSPKKGTASPSKSSATISFDIQYLLTNLAVISVLLAVAL","length":275,"molWeight":29397,"crc64":"581E34174C4E047B","md5":"1EA1543304B5C436710BCBAF448E017F"},"extraAttributes":{"countByFeatureType":{"Domain":1,"Region":1,"Compositional bias":1,"Non-terminal residue":2},"uniParcId":"UPI00015C0D09"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"W0TIL8","uniProtkbId":"W0TIL8_BATDE","entryAudit":{"firstPublicDate":"2014-03-19","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2014-03-19","entryVersion":34,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Batrachochytrium dendrobatidis","commonName":"Frog chytrid fungus","taxonId":109871,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42883.1"}],"lineage":["Eukaryota","Fungi","Fungi incertae sedis","chytridiomyceta","Chytridiomycota","Chytridiomycotina","Chytridiomycetes","Rhizophydiales","Rhizophydiales incertae sedis","Batrachochytrium"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42883.1"}],"value":"Indoleamine 2,3-dioxygenase gamma-isoform"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42883.1"}],"value":"IDO-gamma"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00007119"}],"value":"Belongs to the indoleamine 2,3-dioxygenase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Binding site","location":{"start":{"value":394,"modifier":"EXACT"},"end":{"value":394,"modifier":"EXACT"}},"description":"proximal binding residue","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:60344"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600898-1"}],"ligand":{"name":"heme b","id":"ChEBI:CHEBI:60344"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42883.1"}],"id":"KW-0223","category":"Molecular function","name":"Dioxygenase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600898-1"}],"id":"KW-0349","category":"Ligand","name":"Heme"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600898-1"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"},{"evidenceCode":"ECO:0000256","source":"PIRSR","id":"PIRSR600898-1"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42883.1"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-FCVN2K6ALQ85J","citationType":"submission","authors":["Yuasa H.","Okada Y."],"title":"cDNA sequences of indoleamine 2,3-dioxygenases of Rhizopus delemar and Batrachochytrium dendrobatidis.","publicationDate":"JAN-2014","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42883.1"}],"value":"NBRC 106979","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"BAO42883.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB902916","properties":[{"key":"ProteinId","value":"BAO42883.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"AlphaFoldDB","id":"W0TIL8","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"AAMEDMW","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"GO","id":"GO:0020037","properties":[{"key":"GoTerm","value":"F:heme binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0046872","properties":[{"key":"GoTerm","value":"F:metal ion binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016702","properties":[{"key":"GoTerm","value":"F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-ARBA"}]},{"database":"GO","id":"GO:0006569","properties":[{"key":"GoTerm","value":"P:L-tryptophan catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"FunFam","id":"1.20.58.480:FF:000005","properties":[{"key":"EntryName","value":"Indoleamine 2,3-dioxygenase family protein"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.58.480","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR000898","properties":[{"key":"EntryName","value":"Indolamine_dOase"}]},{"database":"InterPro","id":"IPR037217","properties":[{"key":"EntryName","value":"Trp/Indoleamine_2_3_dOase-like"}]},{"database":"PANTHER","id":"PTHR28657","properties":[{"key":"EntryName","value":"INDOLEAMINE 2,3-DIOXYGENASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR28657:SF3","properties":[{"key":"EntryName","value":"INDOLEAMINE 2,3-DIOXYGENASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01231","properties":[{"key":"EntryName","value":"IDO"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF140959","properties":[{"key":"EntryName","value":"Indolic compounds 2,3-dioxygenase-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MAARNTVKASSILSLATASIAARRSFTQYLPSDHLKDPTCPQFMVGKENGFLPRQDPLVELPSEFKELESLLQRMPLTTAKGEVGLLAKGEFGKAVAAELPEYNVDHITDSQVLNALYRDYCFATSAYLLEPCDIYFREKKDYGLGRDVLPRNIAVPLAKVSEKLGAKPFLEYTQGYGLYNFTRLDKTKPIVYGNVRPIRYFAGMPSETGFILVHVAMAANSSKQVTHVLGALDAVKANDRTQFDLELHGILSAMQSVNAAMENMWTVSAPKDYMKYRTFIMGTKNQPMFPKGVVYEGVSPEPTFYRGETGANDSIIPTADNFLELTGSMPDNPLTEILRDFRSYRPANHTDFLTWLEKEAKTLGVRAYSVQNSTSAVRYLAILDQIREYRARHWNFTKEYIIKWTDHPVATGGSPITTWLPNQLESVLRAIEEISKSIHPAQLSEEDKKLSKELLDRAEVQRRILTREVDALRKRFGQ","length":479,"molWeight":54026,"crc64":"B64F9AE3AD845C85","md5":"F7E3CDA467E92AA769B399AEB8DB4721"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Binding site":1},"uniParcId":"UPI00020FA589"}}]}