{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"E7EDQ7","uniProtkbId":"E7EDQ7_9GAMM","entryAudit":{"firstPublicDate":"2011-03-08","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2011-03-08","entryVersion":85,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Thioalkalivibrio paradoxus","taxonId":108010,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ADV18468.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Chromatiales","Ectothiorhodospiraceae","Thioalkalivibrio"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00011887"}],"value":"nitrite reductase (cytochrome; ammonia-forming)"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00011887"}],"value":"1.7.2.2"}]}},"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"6 Fe(III)-[cytochrome c] + NH4(+) + 2 H2O = 6 Fe(II)-[cytochrome c] + nitrite + 8 H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:13089"},{"database":"Rhea","id":"RHEA-COMP:10350"},{"database":"Rhea","id":"RHEA-COMP:14399"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:16301"},{"database":"ChEBI","id":"CHEBI:28938"},{"database":"ChEBI","id":"CHEBI:29033"},{"database":"ChEBI","id":"CHEBI:29034"}],"ecNumber":"1.7.2.2","evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00049131"}]}},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00004196"}],"value":"Cell envelope","id":"SL-0036"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00009288"}],"value":"Belongs to the cytochrome c-552 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":28,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}]},{"type":"Chain","location":{"start":{"value":29,"modifier":"EXACT"},"end":{"value":553,"modifier":"EXACT"}},"description":"nitrite reductase (cytochrome; ammonia-forming)","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"featureId":"PRO_5003217312"},{"type":"Region","location":{"start":{"value":108,"modifier":"EXACT"},"end":{"value":127,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":108,"modifier":"EXACT"},"end":{"value":120,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Binding site","location":{"start":{"value":42,"modifier":"EXACT"},"end":{"value":42,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"1","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":45,"modifier":"EXACT"},"end":{"value":45,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"1","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":46,"modifier":"EXACT"},"end":{"value":46,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"1","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":46,"modifier":"EXACT"},"end":{"value":46,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"1","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":58,"modifier":"EXACT"},"end":{"value":58,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"2","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":58,"modifier":"EXACT"},"end":{"value":58,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"2","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":63,"modifier":"EXACT"},"end":{"value":63,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"3","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":66,"modifier":"EXACT"},"end":{"value":66,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"3","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":67,"modifier":"EXACT"},"end":{"value":67,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"3","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":67,"modifier":"EXACT"},"end":{"value":67,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"3","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":72,"modifier":"EXACT"},"end":{"value":72,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"1","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":72,"modifier":"EXACT"},"end":{"value":72,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"1","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":84,"modifier":"EXACT"},"end":{"value":84,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"1"}},{"type":"Binding site","location":{"start":{"value":94,"modifier":"EXACT"},"end":{"value":94,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"2","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":97,"modifier":"EXACT"},"end":{"value":97,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"2","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":98,"modifier":"EXACT"},"end":{"value":98,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"2","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":98,"modifier":"EXACT"},"end":{"value":98,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"2","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":101,"modifier":"EXACT"},"end":{"value":101,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"4"}},{"type":"Binding site","location":{"start":{"value":112,"modifier":"EXACT"},"end":{"value":112,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"5"}},{"type":"Binding site","location":{"start":{"value":142,"modifier":"EXACT"},"end":{"value":142,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"6"}},{"type":"Binding site","location":{"start":{"value":145,"modifier":"EXACT"},"end":{"value":145,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"5"}},{"type":"Binding site","location":{"start":{"value":147,"modifier":"EXACT"},"end":{"value":147,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"5","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":147,"modifier":"EXACT"},"end":{"value":147,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"5","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":159,"modifier":"EXACT"},"end":{"value":159,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"6"}},{"type":"Binding site","location":{"start":{"value":169,"modifier":"EXACT"},"end":{"value":169,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"7"}},{"type":"Binding site","location":{"start":{"value":170,"modifier":"EXACT"},"end":{"value":170,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"7"}},{"type":"Binding site","location":{"start":{"value":212,"modifier":"EXACT"},"end":{"value":212,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"6","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":215,"modifier":"EXACT"},"end":{"value":215,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"6","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":216,"modifier":"EXACT"},"end":{"value":216,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"6","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":255,"modifier":"EXACT"},"end":{"value":255,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"4","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":258,"modifier":"EXACT"},"end":{"value":258,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"4","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":259,"modifier":"EXACT"},"end":{"value":259,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"4","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":259,"modifier":"EXACT"},"end":{"value":259,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"4","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":262,"modifier":"EXACT"},"end":{"value":262,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"3","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":262,"modifier":"EXACT"},"end":{"value":262,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"3","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":267,"modifier":"EXACT"},"end":{"value":267,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"3"}},{"type":"Binding site","location":{"start":{"value":304,"modifier":"EXACT"},"end":{"value":304,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"1"}},{"type":"Binding site","location":{"start":{"value":304,"modifier":"EXACT"},"end":{"value":304,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"3"}},{"type":"Binding site","location":{"start":{"value":305,"modifier":"EXACT"},"end":{"value":305,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"1"}},{"type":"Binding site","location":{"start":{"value":310,"modifier":"EXACT"},"end":{"value":310,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"3"}},{"type":"Binding site","location":{"start":{"value":324,"modifier":"EXACT"},"end":{"value":324,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"5","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":327,"modifier":"EXACT"},"end":{"value":327,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"5","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":328,"modifier":"EXACT"},"end":{"value":328,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"5","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":328,"modifier":"EXACT"},"end":{"value":328,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"5","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":330,"modifier":"EXACT"},"end":{"value":330,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108"}},{"type":"Binding site","location":{"start":{"value":331,"modifier":"EXACT"},"end":{"value":331,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108"}},{"type":"Binding site","location":{"start":{"value":386,"modifier":"EXACT"},"end":{"value":386,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108"}},{"type":"Binding site","location":{"start":{"value":388,"modifier":"EXACT"},"end":{"value":388,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29108"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"}],"ligand":{"name":"Ca(2+)","id":"ChEBI:CHEBI:29108"}},{"type":"Binding site","location":{"start":{"value":399,"modifier":"EXACT"},"end":{"value":399,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"7"}},{"type":"Binding site","location":{"start":{"value":400,"modifier":"EXACT"},"end":{"value":400,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"7","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":400,"modifier":"EXACT"},"end":{"value":400,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"7","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":407,"modifier":"EXACT"},"end":{"value":407,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"8","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":410,"modifier":"EXACT"},"end":{"value":410,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"8","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":411,"modifier":"EXACT"},"end":{"value":411,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"8","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":411,"modifier":"EXACT"},"end":{"value":411,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"8","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":414,"modifier":"EXACT"},"end":{"value":414,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"4"}},{"type":"Binding site","location":{"start":{"value":424,"modifier":"EXACT"},"end":{"value":424,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"4"}},{"type":"Binding site","location":{"start":{"value":426,"modifier":"EXACT"},"end":{"value":426,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"4","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":426,"modifier":"EXACT"},"end":{"value":426,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"4","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":430,"modifier":"EXACT"},"end":{"value":430,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"8"}},{"type":"Binding site","location":{"start":{"value":432,"modifier":"EXACT"},"end":{"value":432,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"8"}},{"type":"Binding site","location":{"start":{"value":439,"modifier":"EXACT"},"end":{"value":439,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"7","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":442,"modifier":"EXACT"},"end":{"value":442,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"7","note":"covalent"}},{"type":"Binding site","location":{"start":{"value":443,"modifier":"EXACT"},"end":{"value":443,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"7","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":443,"modifier":"EXACT"},"end":{"value":443,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"7","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":459,"modifier":"EXACT"},"end":{"value":459,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"8"}},{"type":"Binding site","location":{"start":{"value":514,"modifier":"EXACT"},"end":{"value":514,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"6"}},{"type":"Binding site","location":{"start":{"value":519,"modifier":"EXACT"},"end":{"value":519,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"8","note":"axial binding residue"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}},{"type":"Binding site","location":{"start":{"value":519,"modifier":"EXACT"},"end":{"value":519,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:61717"},{"database":"ChEBI","id":"CHEBI:18248"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"ligand":{"name":"heme c","id":"ChEBI:CHEBI:61717","label":"8","note":"covalent"},"ligandPart":{"name":"Fe","id":"ChEBI:CHEBI:18248"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3TTB"}],"id":"KW-0002","category":"Technical term","name":"3D-structure"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022837"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"}],"id":"KW-0106","category":"Ligand","name":"Calcium"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022617"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"}],"id":"KW-0349","category":"Ligand","name":"Heme"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023004"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"}],"id":"KW-0408","category":"Ligand","name":"Iron"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022723"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00023002"}],"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00022729"},{"evidenceCode":"ECO:0000256","source":"SAM","id":"SignalP"}],"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"22935005","citationType":"journal article","authors":["Tikhonova T.","Tikhonov A.","Trofimov A.","Polyakov K.","Boyko K.","Cherkashin E.","Rakitina T.","Sorokin D.","Popov V."],"citationCrossReferences":[{"database":"PubMed","id":"22935005"},{"database":"DOI","id":"10.1111/j.1742-4658.2012.08811.x"}],"title":"Comparative structural and functional analysis of two octaheme nitrite reductases from closely related Thioalkalivibrio species.","publicationDate":"2012","journal":"FEBS J.","firstPage":"4052","lastPage":"4061","volume":"279"},"referencePositions":["X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 29-553 IN COMPLEX WITH CALCIUM AND HEME"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ADV18468.1"}],"value":"180","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"ADV18468.1"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"3SXQ"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"HQ665012","properties":[{"key":"ProteinId","value":"ADV18468.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PDB","id":"3SXQ","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"1.90 A"},{"key":"Chains","value":"A/B=29-553"}]},{"database":"PDB","id":"3TTB","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"2.00 A"},{"key":"Chains","value":"A/B=29-553"}]},{"database":"AlphaFoldDB","id":"E7EDQ7","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"E7EDQ7","properties":[{"key":"Description","value":"-"}]},{"database":"EvolutionaryTrace","id":"E7EDQ7","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0030288","properties":[{"key":"GoTerm","value":"C:outer membrane-bounded periplasmic space"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0020037","properties":[{"key":"GoTerm","value":"F:heme binding"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0042279","properties":[{"key":"GoTerm","value":"F:nitrite reductase (cytochrome, ammonia-forming) activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0019645","properties":[{"key":"GoTerm","value":"P:anaerobic electron transport chain"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"CDD","id":"cd00548","properties":[{"key":"EntryName","value":"NrfA-like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.1130.10:FF:000004","properties":[{"key":"EntryName","value":"Cytochrome c-552"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.287.3080:FF:000001","properties":[{"key":"EntryName","value":"Cytochrome c-552"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.20.140.10:FF:000069","properties":[{"key":"EntryName","value":"Cytochrome c-552"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.287.3080","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.140.10","properties":[{"key":"EntryName","value":"Butyryl-CoA Dehydrogenase, subunit A, domain 3"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.1130.10","properties":[{"key":"EntryName","value":"Flavocytochrome C3, Chain A"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003321","properties":[{"key":"EntryName","value":"Cyt_c552"}]},{"database":"InterPro","id":"IPR036280","properties":[{"key":"EntryName","value":"Multihaem_cyt_sf"}]},{"database":"PANTHER","id":"PTHR30633:SF0","properties":[{"key":"EntryName","value":"CYTOCHROME C-552"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR30633","properties":[{"key":"EntryName","value":"CYTOCHROME C-552 RESPIRATORY NITRITE REDUCTASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02335","properties":[{"key":"EntryName","value":"Cytochrom_C552"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF000243","properties":[{"key":"EntryName","value":"Cyt_c552"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF48695","properties":[{"key":"EntryName","value":"Multiheme cytochromes"},{"key":"MatchStatus","value":"2"}]}],"sequence":{"value":"MNDLNRLGRVGRWVAGAACLFLASAAHAGSGDQLKPVDALQCYDCHTQIEDMHVVGKHATVNCVHCHDATEHVETASARRMGERPVTHTSPEACASCHTAQFNSFASVRHESHPREEKANPRSRSPKFDTLIGAHGFSLEHAEPRSHAFMLVDHFIVDRAYGGRFQYKSWQNVTDGLGAVRGAWTVIEDMDPTTSDQRRFLAQTATAANPVCLNCKTQDHILDWAYMGDEHDAAKWARTSKVVDFARDLHHPVNCYMCHDPHSTEPRVVRDALIHAVVDQGLGTYPYDEAKSEHVTLTPVTFQRGGEDFRKIGLLNVADSNLMCGQCHVEYNCNPGFQQSDGAPVGMDDRRTNHFFWANVFDYAEAAKEIDFFDFTHVTTGAPLPKLQHPELETFWGSTHERNGVTCADCHMPRVKLENGKEYTMHSPRTPRDMMNRACLNCHDGWTEAEAEYAIDYIKNYTHGKIMKAEFWLARMIDLFPVAKRAGVSEDVLNEVRALHYDAHLHWEWWTAENSVGFHNPDQARESLMKSITKSKEGVGKLDAAIDAAVAAN","length":553,"molWeight":62065,"crc64":"87FAB3850F353B1E","md5":"EFBAD63039A5208147090012AC92922C"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Signal":1,"Chain":1,"Region":1,"Compositional bias":1,"Binding site":69},"uniParcId":"UPI0001F48CD1"}},{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"L0GC54","uniProtkbId":"L0GC54_9GAMM","entryAudit":{"firstPublicDate":"2013-03-06","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2013-03-06","entryVersion":19,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Thioalkalivibrio paradoxus","taxonId":108010,"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82611.1"}],"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Chromatiales","Ectothiorhodospiraceae","Thioalkalivibrio"]},"proteinExistence":"4: Predicted","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82611.1"}],"value":"Sulfate thioesterase/sulfate thiohydrolase"}}],"flag":"Fragment"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82611.1"}],"value":"soxB"}}],"features":[{"type":"Non-terminal residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82611.1"}]},{"type":"Non-terminal residue","location":{"start":{"value":263,"modifier":"EXACT"},"end":{"value":263,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82611.1"}]}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82611.1"}],"id":"KW-0378","category":"Molecular function","name":"Hydrolase"}],"references":[{"referenceNumber":1,"citation":{"id":"23237619","citationType":"journal article","authors":["Tourova T.P.","Slobodova N.V.","Bumazhkin B.K.","Kolganova T.V.","Muyzer G.","Sorokin D.Y."],"citationCrossReferences":[{"database":"PubMed","id":"23237619"},{"database":"DOI","id":"10.1111/1574-6941.12056"}],"title":"Analysis of community composition of sulfur-oxidizing bacteria in hypersaline and soda lakes using soxB as a functional molecular marker.","publicationDate":"2013","journal":"FEMS Microbiol. Ecol.","firstPage":"280","lastPage":"289","volume":"84"},"referencePositions":["NUCLEOTIDE SEQUENCE"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82611.1"}],"value":"ARh 1","type":"STRAIN"}],"evidences":[{"evidenceCode":"ECO:0000313","source":"EMBL","id":"AGA82611.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"KC017789","properties":[{"key":"ProteinId","value":"AGA82611.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"AlphaFoldDB","id":"L0GC54","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0030288","properties":[{"key":"GoTerm","value":"C:outer membrane-bounded periplasmic space"},{"key":"GoEvidenceType","value":"IEA:TreeGrafter"}]},{"database":"GO","id":"GO:0016787","properties":[{"key":"GoTerm","value":"F:hydrolase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0009166","properties":[{"key":"GoTerm","value":"P:nucleotide catabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.60.21.10","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.90.780.10","properties":[{"key":"EntryName","value":"5'-Nucleotidase, C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR036907","properties":[{"key":"EntryName","value":"5'-Nucleotdase_C_sf"}]},{"database":"InterPro","id":"IPR006179","properties":[{"key":"EntryName","value":"5_nucleotidase/apyrase"}]},{"database":"InterPro","id":"IPR029052","properties":[{"key":"EntryName","value":"Metallo-depent_PP-like"}]},{"database":"PANTHER","id":"PTHR11575","properties":[{"key":"EntryName","value":"5'-NUCLEOTIDASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR11575:SF42","properties":[{"key":"EntryName","value":"SULFUR OXIDATION PROTEIN SOXB"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR01607","properties":[{"key":"EntryName","value":"APYRASEFAMLY"}]},{"database":"SUPFAM","id":"SSF55816","properties":[{"key":"EntryName","value":"5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56300","properties":[{"key":"EntryName","value":"Metallo-dependent phosphatases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"WEFTFGTDPVMEIFENDFKPNGIDFLAQNFEDRDWGDPVFEPYTIREMNGVPVAVIGQAFPYTSVANPSYMFPDWSFGIRDEHMQRMINECREKGAKVVAILSHNGMVTDMEMARNLEGVDVIMGGHTHDAIPGAVEIENAGGDITLVTNAGSNGKFLGLLDLDVGESGVRDYKFHMLPVFSNLLDADPEMEEHVKKVHQPYEDKLNEELAVTDGVLYRRGNFNGTFDEVILDALREKLDAEVALSPGFRWGVSVLPGQPITF","length":263,"molWeight":29392,"crc64":"18B0F61741C0B4A0","md5":"AECCC22F668663F678E9186F81B5BC32"},"extraAttributes":{"countByFeatureType":{"Non-terminal residue":2},"uniParcId":"UPI0002A8874F"}}]}