{"results":[{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0ABF7PQ65","uniProtkbId":"A0ABF7PQ65_9BACL","entryAudit":{"firstPublicDate":"2025-06-18","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2025-06-18","entryVersion":6,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Kurthia massiliensis","taxonId":1033739,"evidences":[{"evidenceCode":"ECO:0000313","source":"PDB","id":"8XK3"}],"lineage":["Bacteria","Bacillati","Bacillota","Bacilli","Caryophanales","Caryophanaceae","Kurthia"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00035032"}],"value":"Protein argonaute"}}},"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000256","source":"ARBA","id":"ARBA00035012"}],"value":"Belongs to the argonaute family. Long pAgo subfamily"}],"commentType":"SIMILARITY"}],"features":[{"type":"Domain","location":{"start":{"value":417,"modifier":"EXACT"},"end":{"value":724,"modifier":"EXACT"}},"description":"Piwi","evidences":[{"evidenceCode":"ECO:0000259","source":"PROSITE","id":"PS50822"}]},{"type":"Binding site","location":{"start":{"value":527,"modifier":"EXACT"},"end":{"value":527,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29035"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"8XK0"}],"ligand":{"name":"Mn(2+)","id":"ChEBI:CHEBI:29035","label":"1"}},{"type":"Binding site","location":{"start":{"value":596,"modifier":"EXACT"},"end":{"value":596,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29035"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"8XK0"}],"ligand":{"name":"Mn(2+)","id":"ChEBI:CHEBI:29035","label":"1"}},{"type":"Binding site","location":{"start":{"value":737,"modifier":"EXACT"},"end":{"value":737,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29035"}],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"8XK0"}],"ligand":{"name":"Mn(2+)","id":"ChEBI:CHEBI:29035","label":"2"}}],"keywords":[{"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"8XJW"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"8XK0"}],"id":"KW-0002","category":"Technical term","name":"3D-structure"},{"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"8XJW"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"8XK0"}],"id":"KW-0479","category":"Ligand","name":"Metal-binding"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-3NG68RSP0V6KE","citationType":"submission","authors":["Xin T.","Hui D.","Shaowen W."],"title":"Structural and mechanistic insights into a mesophilic prokaryotic Argonaute.","publicationDate":"DEC-2023","submissionDatabase":"PDB data bank"},"referencePositions":["STRUCTURE BY ELECTRON MICROSCOPY (2.85 ANGSTROMS)"],"evidences":[{"evidenceCode":"ECO:0000313","source":"PDB","id":"8XHS"}]},{"referenceNumber":2,"citation":{"id":"39315697","citationType":"journal article","authors":["Tao X.","Ding H.","Wu S.","Wang F.","Xu H.","Li J.","Zhai C.","Li S.","Chen K.","Wu S.","Liu Y.","Ma L."],"citationCrossReferences":[{"database":"PubMed","id":"39315697"},{"database":"DOI","id":"10.1093/nar/gkae820"}],"title":"Structural and mechanistic insights into a mesophilic prokaryotic Argonaute.","publicationDate":"2024","journal":"Nucleic Acids Res.","firstPage":"11895","lastPage":"11910","volume":"52"},"referencePositions":["STRUCTURE BY ELECTRON MICROSCOPY (2.76 ANGSTROMS)"],"evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"8XJW"},{"evidenceCode":"ECO:0007829","source":"PDB","id":"8XK0"}]}],"uniProtKBCrossReferences":[{"database":"RefSeq","id":"WP_010289662.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_HE611000.1"}]},{"database":"PDB","id":"8XHS","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"2.85 A"},{"key":"Chains","value":"A=1-737"}]},{"database":"PDB","id":"8XHV","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"2.81 A"},{"key":"Chains","value":"A=1-737"}]},{"database":"PDB","id":"8XJW","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"2.84 A"},{"key":"Chains","value":"A=1-737"}]},{"database":"PDB","id":"8XJX","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"2.78 A"},{"key":"Chains","value":"A=1-737"}]},{"database":"PDB","id":"8XK0","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"2.96 A"},{"key":"Chains","value":"A=1-737"}]},{"database":"PDB","id":"8XK3","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"2.76 A"},{"key":"Chains","value":"A=1-737"}]},{"database":"PDB","id":"8XK4","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"2.94 A"},{"key":"Chains","value":"A=1-737"}]},{"database":"AlphaFoldDB","id":"A0ABF7PQ65","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"A0ABF7PQ65","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0003676","properties":[{"key":"GoTerm","value":"F:nucleic acid binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"Gene3D","id":"3.40.50.2300","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.420.10","properties":[{"key":"EntryName","value":"Ribonuclease H-like superfamily/Ribonuclease H"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003165","properties":[{"key":"EntryName","value":"Piwi"}]},{"database":"InterPro","id":"IPR012337","properties":[{"key":"EntryName","value":"RNaseH-like_sf"}]},{"database":"InterPro","id":"IPR036397","properties":[{"key":"EntryName","value":"RNaseH_sf"}]},{"database":"PANTHER","id":"PTHR22891","properties":[{"key":"EntryName","value":"EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02171","properties":[{"key":"EntryName","value":"Piwi"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00950","properties":[{"key":"EntryName","value":"Piwi"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF53098","properties":[{"key":"EntryName","value":"Ribonuclease H-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50822","properties":[{"key":"EntryName","value":"PIWI"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MEAYITEMVSRERANELEVYVYVFPRKQSDNNYEGVYHIMRAWQRANDLPLAYNQHTIMAFSPVRHMCGYTPMETQKRHINIDSPFERALLERLIKNSLIFTAERHLHAKRVGHALRLNQVQQIRQVIIYEAIELYVNIIENRISIGFHLTHQFEYVYTLQSMIEQGKTIRPGMRVVHSNGRQHYTYTVENVATYGVTDRCPLLQTSIYQYYVEKGAQHILRTFTRSTRVIHVRTKEQRLSYAATLLKPLCTFETMQPQDVLNVSKCIKLSASKRMKCTYRWIQQLRAQYRHLTFAPNPFTIAQNGYKLDQLSTPKVHFHRDYATVVSGMKTGKLYKGGNIKISVLFDEDFYLKHHITKKDIYQFIAVLQKIAIAQGVNMTISTSTKSITGKFTDDFFHHFTEEVEALQPIFAQTTVLAFITSTHLSNKKTRSYQLLKQYFGGKWDIASQVITEKTIEAFQKILHKHGLKNFYPNDEQHCLRVIDVLKNESFYYTVMNILLGVYVKSGIQPWILANTTHSDCFIGIDVSHENGNSAAGMMNVIGSQGHLIQQAPLNGILAGEKIDDTLLANLLKQMIKAYHTQFQRFPKHITIHRDGFWREHTALVEKIMSHYEITYDIVEIIKKPNRRMAFFNSVDNTFSTRQGTVYQRGNEAFLCATNPQQKVGMAQPIKIHQVTKTLPFSHIIEDVYNLSFLHIHAMNKMRLPATIHYADLSATAYQRGQVMPRSGNQTNLPFV","length":737,"molWeight":85363,"crc64":"C6AE3F56CDA42613","md5":"2237A2F9132CFD2B4B88B5259DF7053D"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Domain":1,"Binding site":3},"uniParcId":"UPI00028800BB"}}]}