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Class I can self-assemble into an outermost layer of rodlet bundles on aerial cell surfaces, conferring cellular hydrophobicity that supports fungal growth, development and dispersal; whereas Class II form highly ordered films at water-air interfaces through intermolecular interactions but contribute nothing to the rodlet structure (Probable). Hyd1 is a class I hydrophobin that is involved in plant root attachment and colonization, and that might also protect the growing hyphae from locally synthesized plant defense compounds during the first stages of cucumber interaction, allowing this opportunistic, non-pathogenic fungus to colonize the intercellular spaces of the plant root (PubMed:20507444)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q04571"}],"value":"Self-assembles to form functional amyloid fibrils called rodlets. 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Constitutively expressed at low levels in mycelia in young cultures but gene expression is not detected in sporulating hyphae or in non-germinating spores (PubMed:20507444). Carbon limitation stimulates expression whereas nitrogen or phosphate starvation down-regulate expression (PubMed:20507444)"}],"commentType":"INDUCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"20507444"}],"value":"Does not affect mycoparasitic activity but alters wettability and severely impairs root attachment and colonization"}],"commentType":"DISRUPTION PHENOTYPE"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the fungal hydrophobin family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":18,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Chain","location":{"start":{"value":19,"modifier":"EXACT"},"end":{"value":145,"modifier":"EXACT"}},"description":"Class I hydrophobin 1","featureId":"PRO_5027857257"},{"type":"Region","location":{"start":{"value":38,"modifier":"EXACT"},"end":{"value":75,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":53,"modifier":"EXACT"},"end":{"value":70,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Glycosylation","location":{"start":{"value":108,"modifier":"EXACT"},"end":{"value":108,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00498"}],"featureId":""},{"type":"Disulfide bond","location":{"start":{"value":88,"modifier":"EXACT"},"end":{"value":118,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P79073"}]},{"type":"Disulfide bond","location":{"start":{"value":95,"modifier":"EXACT"},"end":{"value":112,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P79073"}]},{"type":"Disulfide bond","location":{"start":{"value":96,"modifier":"EXACT"},"end":{"value":106,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P79073"}]},{"type":"Disulfide bond","location":{"start":{"value":119,"modifier":"EXACT"},"end":{"value":128,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P79073"}]}],"keywords":[{"id":"KW-0134","category":"Cellular component","name":"Cell wall"},{"id":"KW-1015","category":"PTM","name":"Disulfide bond"},{"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"id":"KW-0964","category":"Cellular component","name":"Secreted"},{"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"33004460","citationType":"journal article","authors":["Takahashi H.","Sakagawa E.","Toyoda R.","Motomura T.","Murase M.","Takahashi A.","Fukuyoshi S.","Kanamasa S."],"citationCrossReferences":[{"database":"PubMed","id":"33004460"},{"database":"DOI","id":"10.1128/mra.00958-20"}],"title":"Draft Genome Sequence of Glycoside Hydrolase-Producing Trichoderma asperellum Strain IC-1.","publicationDate":"2020","journal":"Microbiol. 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Plays roles in interactions with both biotic and abiotic environmental conditions such as the presence of the pathogen Alternaria alternata or nutrient starvation conditions (PubMed:25644947)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P79073"}],"value":"Homodimer (By similarity). 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