{"results":[{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P54855","secondaryAccessions":["A6NDX0","A6NNJ4","A8K054","P23765","Q9UK63"],"uniProtkbId":"UDB15_HUMAN","entryAudit":{"firstPublicDate":"1996-10-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2011-05-03","entryVersion":206,"sequenceVersion":3},"annotationScore":5.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"18719240"}],"value":"UDP-glucuronosyltransferase 2B15"},"shortNames":[{"value":"UDPGT 2B15"},{"value":"UGT2B15"}],"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16595710"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"18719240"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23288867"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"7835232"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9295060"}],"value":"2.4.1.17"}]},"alternativeNames":[{"fullName":{"value":"HLUG4"}},{"fullName":{"value":"UDP-glucuronosyltransferase 2B8"},"shortNames":[{"value":"UDPGT 2B8"}]},{"fullName":{"value":"UDPGTh-3"}}],"flag":"Precursor"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"HGNC","id":"HGNC:12546"}],"value":"UGT2B15"},"synonyms":[{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"2116769"}],"value":"UGT2B8"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P36511"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16595710"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"18719240"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23288867"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"7835232"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9295060"}],"value":"UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile (PubMed:16595710, PubMed:18719240, PubMed:23288867, PubMed:7835232, PubMed:9295060). 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