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Interacts with TMEM14B; this interaction increases IQGAP1 phosphorylation and induces its nuclear translocation (PubMed:29033352). Interacts with SASH1 (PubMed:23333244). Interacts with PJVK (By similarity). Interacts with SLC26A4; this interaction enhances the chloride-bicarbonate exchange activity of SLC26A4 (PubMed:35601831). Interacts with SVEP1 (By similarity). 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