{"results":[{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P48729","secondaryAccessions":["D3DQG0","D3DQG1","Q4JJA0","Q5U046","Q5U047","Q6FGA2","Q71TU5","Q96HD2","Q9UDK3"],"uniProtkbId":"KC1A_HUMAN","entryAudit":{"firstPublicDate":"1996-02-01","lastAnnotationUpdateDate":"2026-11-04","lastSequenceUpdateDate":"2003-05-23","entryVersion":238,"sequenceVersion":2},"annotationScore":5.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Casein kinase I isoform alpha"},"shortNames":[{"value":"CKI-alpha"}],"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11955436"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"31932442"}],"value":"2.7.11.1"}]},"alternativeNames":[{"fullName":{"value":"CK1"}}]},"genes":[{"geneName":{"value":"CSNK1A1"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8BK63"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11955436"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"1409656"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"18305108"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22017875"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22017877"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23902688"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"31932442"}],"value":"Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates (PubMed:11955436, PubMed:1409656, PubMed:18305108, PubMed:23902688). 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