{"results":[{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q92851","secondaryAccessions":["Q68HC0","Q6KF62","Q6KF63","Q8IUP5","Q8WYQ8","Q99845","Q9Y2U6","Q9Y2U7"],"uniProtkbId":"CASPA_HUMAN","entryAudit":{"firstPublicDate":"1997-11-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2001-01-11","entryVersion":243,"sequenceVersion":3},"annotationScore":5.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Caspase-10"},"shortNames":[{"value":"CASP-10"}],"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16916640"}],"value":"3.4.22.63"}]},"alternativeNames":[{"fullName":{"value":"Apoptotic protease Mch-4"}},{"fullName":{"value":"FAS-associated death domain protein interleukin-1B-converting enzyme 2"},"shortNames":[{"value":"FLICE2"}]},{"fullName":{"value":"ICE-like apoptotic protease 4"}}],"contains":[{"recommendedName":{"fullName":{"value":"Caspase-10 subunit p23/17"}}},{"recommendedName":{"fullName":{"value":"Caspase-10 subunit p12"}}}],"flag":"Precursor"},"genes":[{"geneName":{"value":"CASP10"},"synonyms":[{"value":"MCH4"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11717445"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16916640"}],"value":"Involved in the activation cascade of caspases responsible for apoptosis execution. 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