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Mechanistically, enhances the ubiquitination of TRAF3 and TRAF6 as well as the phosphorylation of TAK1 and TBK1 (PubMed:34011520)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P05027"},{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P07340"},{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P14094"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22328087"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"25902260"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"34011520"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"35803952"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"36075933"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"39596464"}],"value":"The sodium/potassium-transporting ATPase is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit, called FXYD. 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