{"results":[{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q92482","secondaryAccessions":["A8K843","B2RE16","D3DRL3","O00108","Q6FGT2","Q6FGW6"],"uniProtkbId":"AQP3_HUMAN","entryAudit":{"firstPublicDate":"1997-11-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1997-11-01","entryVersion":204,"sequenceVersion":2},"annotationScore":5.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"20724658"}],"value":"Aquaporin-3"},"shortNames":[{"value":"AQP-3"}]},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"30420639"}],"value":"Aquaglyceroporin-3"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"7558005"},{"evidenceCode":"ECO:0000312","source":"HGNC","id":"HGNC:636"}],"value":"AQP3"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P47862"},{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8R2N1"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"12239222"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"20724658"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"30420639"}],"value":"Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient (PubMed:12239222, PubMed:30420639). 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