{"entryType":"UniProtKB unreviewed (TrEMBL)","primaryAccession":"A0A2R8YCT7","uniProtkbId":"A0A2R8YCT7_HUMAN","entryAudit":{"firstPublicDate":"1111-11-10","lastAnnotationUpdateDate":"1111-11-10","lastSequenceUpdateDate":"1111-11-10","entryVersion":1,"sequenceVersion":1},"annotationScore":0.0,"proteinExistence":"5: Uncertain","proteinDescription":{"submissionNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0008006","source":"Google","id":"ProtNLM2","properties":[{"key":"model_score","value":"0.30"},{"key":"string_match_text","value":"3.50.80.10"},{"key":"string_match_location","value":"Gene3D"},{"key":"string_match_type","value":"exact_sanitized"}]}],"value":"D-tyrosyl-tRNA(Tyr) deacylase"}}]},"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0008006","source":"Google","id":"ProtNLM2","properties":[{"key":"model_score","value":"0.82"},{"key":"phmmer_accession","value":"Q8TEA8"},{"key":"phmmer_score","value":"268.3"}]}],"value":"An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality"}],"commentType":"FUNCTION"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-FC84BSHK1H4IL","citationType":"unpublished observations"},"referencePositions":["required field"]}],"extraAttributes":{"countByCommentType":{"FUNCTION":1}}}