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Positively regulates trafficking of the secretory proteins SERPINA1/alpha1-antitrypsin and HP/haptoglobin (PubMed:31142615)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"15308636"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"31142615"}],"value":"Forms homodimers (PubMed:31142615). May form a heteromeric complex composed of ERGIC1, ERGIC2 and ERGIC3 (PubMed:31142615). Within the complex, the interaction with ERGIC1 is direct (PubMed:31142615). Interacts with ERGIC1/ERGIC32 (PubMed:15308636, PubMed:31142615). Interacts with ERGIC2, the interaction is required for the stable expression of both proteins (PubMed:31142615). Interacts with MARCHF2 (PubMed:31142615). Interacts with alpha1-antitrypsin/SERPINA1 and HP/haptoglobin 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