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Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and spindle microtubules. The outer kinetochore is made up of the ten-subunit KMN network complex, comprising the MIS12, NDC80 and KNL1 complexes, and auxiliary microtubule-associated components such as the SKA complex; together they connect the outer kinetochore with the inner kinetochore, bind microtubules, and mediate interactions with mitotic checkpoint proteins that delay anaphase until chromosomes are bioriented on the spindle (By similarity). The SKA complex is loaded onto bioriented kinetochores and it facilitates chromosome congression by stabilizing microtubules and end-on attachment of the NDC80 complex to depolymerizing spindle microtubules, thereby assisting the poleward-moving kinetochore in withstanding microtubule pulling forces (PubMed:23085020). The complex associates with dynamic microtubule plus-ends and can track both depolymerizing and elongating microtubules (By similarity). The complex recruits protein phosphatase 1 (PP1) to the kinetochore in prometaphase and metaphase, to oppose spindle assembly checkpoint signaling and promote the onset of anaphase (By similarity). In the complex, it mediates interactions with microtubules (PubMed:23085020). During meiosis the SKA complex stabilizes the meiotic spindle and is required for its migration to the cortex (By similarity)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23085020"}],"value":"Component of the SKA complex, composed of two copies of ska-1 and a single copy of ska-3. The core complex associates with microtubules and may form dimeric assemblies. 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