{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q9VMH0","secondaryAccessions":["Q2MV53","Q8MSM0"],"uniProtkbId":"TECT_DROME","entryAudit":{"firstPublicDate":"2006-04-04","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2014-04-16","entryVersion":134,"sequenceVersion":4},"annotationScore":5.0,"organism":{"scientificName":"Drosophila melanogaster","commonName":"Fruit fly","taxonId":7227,"lineage":["Eukaryota","Metazoa","Ecdysozoa","Arthropoda","Altocrustacea","Allotriocarida","Hexapoda","Insecta","Pterygota","Neoptera","Eumetabola","Endopterygota","Aparaglossata","Panorpida","Diptera","Brachycera","Muscomorpha","Ephydroidea","Drosophilidae","Drosophila","Sophophora"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"12537572"},{"evidenceCode":"ECO:0000312","source":"FlyBase","id":"FBgn0261697"}],"value":"Tectonic"}},"alternativeNames":[{"fullName":{"value":"dTectonic"}}],"flag":"Precursor"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"FlyBase","id":"FBgn0261697"}],"value":"tctn"},"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000312","source":"FlyBase","id":"FBgn0261697"}],"value":"CG9227"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"27646273"}],"value":"Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia (PubMed:27646273). Has a role in ciliary structure and function (PubMed:27646273)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"27646273"}],"value":"Probable component of the tectonic-like complex (also named MKS complex), composed of B9d1, B9d2, Cc2d2a, Mks1 and tctn"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"27646273"}],"value":"Localizes at the transition zone, a region between the basal body and the ciliary axoneme (PubMed:27646273). Co-localizes with the tectonic-like complex (PubMed:27646273)"}]},"subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Membrane","id":"SL-0162"},"topology":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Single-pass type I membrane protein","id":"SL-9905"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"27646273"}],"value":"Cytoplasm, cytoskeleton, cilium basal body","id":"SL-0087"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"27646273"}],"value":"Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole","id":"SL-0046"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"27646273"}],"value":"Expressed in chordotonal neurons in the antennae and male germ cells (at protein level)"}],"commentType":"TISSUE SPECIFICITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"27646273"}],"value":"Simultaneous knockout of B9d2 and tctn is viable and does not show sensory behavioral defects (PubMed:27646273). Males produce motile sperm and show only slightly reduced fertility (PubMed:27646273). Sperm flagella show weak ultrastructural defects including broken and disorganised structure (PubMed:27646273). Length of the transition zone is decreased and recruitment of the tectonic-like complex compromised (PubMed:27646273)"}],"commentType":"DISRUPTION PHENOTYPE"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the tectonic family"}],"commentType":"SIMILARITY"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous termination","sequence":"AAM50568.1","note":"Truncated C-terminus.","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":19,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Chain","location":{"start":{"value":20,"modifier":"EXACT"},"end":{"value":657,"modifier":"EXACT"}},"description":"Tectonic","featureId":"PRO_0000229803"},{"type":"Topological domain","location":{"start":{"value":20,"modifier":"EXACT"},"end":{"value":629,"modifier":"EXACT"}},"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":630,"modifier":"EXACT"},"end":{"value":650,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Topological domain","location":{"start":{"value":651,"modifier":"EXACT"},"end":{"value":657,"modifier":"EXACT"}},"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Region","location":{"start":{"value":35,"modifier":"EXACT"},"end":{"value":57,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":35,"modifier":"EXACT"},"end":{"value":51,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Glycosylation","location":{"start":{"value":29,"modifier":"EXACT"},"end":{"value":29,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Glycosylation","location":{"start":{"value":98,"modifier":"EXACT"},"end":{"value":98,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Glycosylation","location":{"start":{"value":103,"modifier":"EXACT"},"end":{"value":103,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Glycosylation","location":{"start":{"value":289,"modifier":"EXACT"},"end":{"value":289,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Glycosylation","location":{"start":{"value":331,"modifier":"EXACT"},"end":{"value":331,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Glycosylation","location":{"start":{"value":349,"modifier":"EXACT"},"end":{"value":349,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Glycosylation","location":{"start":{"value":385,"modifier":"EXACT"},"end":{"value":385,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Glycosylation","location":{"start":{"value":413,"modifier":"EXACT"},"end":{"value":413,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Glycosylation","location":{"start":{"value":482,"modifier":"EXACT"},"end":{"value":482,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Glycosylation","location":{"start":{"value":502,"modifier":"EXACT"},"end":{"value":502,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Sequence conflict","location":{"start":{"value":6,"modifier":"EXACT"},"end":{"value":6,"modifier":"EXACT"}},"description":"in Ref. 1; ABB90565 and 4; AAM50568","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"P","alternativeSequences":["L"]}},{"type":"Sequence conflict","location":{"start":{"value":11,"modifier":"EXACT"},"end":{"value":11,"modifier":"EXACT"}},"description":"in Ref. 1; ABB90565 and 4; AAM50568","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"C","alternativeSequences":["F"]}},{"type":"Sequence conflict","location":{"start":{"value":321,"modifier":"EXACT"},"end":{"value":323,"modifier":"EXACT"}},"description":"in Ref. 1; ABB90565 and 4; AAM50568","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"NKS","alternativeSequences":["DKA"]}},{"type":"Sequence conflict","location":{"start":{"value":341,"modifier":"EXACT"},"end":{"value":341,"modifier":"EXACT"}},"description":"in Ref. 1; ABB90565 and 4; AAM50568","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"H","alternativeSequences":["Q"]}},{"type":"Sequence conflict","location":{"start":{"value":384,"modifier":"EXACT"},"end":{"value":384,"modifier":"EXACT"}},"description":"in Ref. 1; ABB90565 and 4; AAM50568","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"L","alternativeSequences":["P"]}},{"type":"Sequence conflict","location":{"start":{"value":390,"modifier":"EXACT"},"end":{"value":390,"modifier":"EXACT"}},"description":"in Ref. 1; ABB90565 and 4; AAM50568","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"K","alternativeSequences":["N"]}},{"type":"Sequence conflict","location":{"start":{"value":426,"modifier":"EXACT"},"end":{"value":426,"modifier":"EXACT"}},"description":"in Ref. 1; ABB90565 and 4; AAM50568","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"L","alternativeSequences":["S"]}},{"type":"Sequence conflict","location":{"start":{"value":462,"modifier":"EXACT"},"end":{"value":462,"modifier":"EXACT"}},"description":"in Ref. 1; ABB90565 and 4; AAM50568","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"I","alternativeSequences":["V"]}},{"type":"Sequence conflict","location":{"start":{"value":501,"modifier":"EXACT"},"end":{"value":501,"modifier":"EXACT"}},"description":"in Ref. 1; ABB90565 and 4; AAM50568","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"H","alternativeSequences":["D"]}},{"type":"Sequence conflict","location":{"start":{"value":508,"modifier":"EXACT"},"end":{"value":508,"modifier":"EXACT"}},"description":"in Ref. 1; ABB90565 and 4; AAM50568","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"D","alternativeSequences":["A"]}}],"keywords":[{"id":"KW-0966","category":"Cellular component","name":"Cell projection"},{"id":"KW-0970","category":"Biological process","name":"Cilium biogenesis/degradation"},{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0206","category":"Cellular component","name":"Cytoskeleton"},{"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0732","category":"Domain","name":"Signal"},{"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"16357211","citationType":"journal article","authors":["Reiter J.F.","Skarnes W.C."],"citationCrossReferences":[{"database":"PubMed","id":"16357211"},{"database":"DOI","id":"10.1101/gad.1363606"}],"title":"Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition.","publicationDate":"2006","journal":"Genes Dev.","firstPage":"22","lastPage":"27","volume":"20"},"referencePositions":["NUCLEOTIDE SEQUENCE [MRNA]"]},{"referenceNumber":2,"citation":{"id":"10731132","citationType":"journal article","authors":["Adams M.D.","Celniker S.E.","Holt R.A.","Evans C.A.","Gocayne J.D.","Amanatides P.G.","Scherer S.E.","Li P.W.","Hoskins R.A.","Galle R.F.","George R.A.","Lewis S.E.","Richards S.","Ashburner M.","Henderson S.N.","Sutton G.G.","Wortman J.R.","Yandell M.D.","Zhang Q.","Chen L.X.","Brandon R.C.","Rogers Y.-H.C.","Blazej R.G.","Champe M.","Pfeiffer B.D.","Wan K.H.","Doyle C.","Baxter E.G.","Helt G.","Nelson C.R.","Miklos G.L.G.","Abril J.F.","Agbayani A.","An H.-J.","Andrews-Pfannkoch C.","Baldwin D.","Ballew R.M.","Basu A.","Baxendale J.","Bayraktaroglu L.","Beasley E.M.","Beeson K.Y.","Benos P.V.","Berman B.P.","Bhandari D.","Bolshakov S.","Borkova D.","Botchan M.R.","Bouck J.","Brokstein P.","Brottier P.","Burtis K.C.","Busam D.A.","Butler H.","Cadieu E.","Center A.","Chandra I.","Cherry J.M.","Cawley S.","Dahlke C.","Davenport L.B.","Davies P.","de Pablos B.","Delcher A.","Deng Z.","Mays A.D.","Dew I.","Dietz S.M.","Dodson K.","Doup L.E.","Downes M.","Dugan-Rocha S.","Dunkov B.C.","Dunn P.","Durbin K.J.","Evangelista C.C.","Ferraz C.","Ferriera S.","Fleischmann W.","Fosler C.","Gabrielian A.E.","Garg N.S.","Gelbart W.M.","Glasser K.","Glodek A.","Gong F.","Gorrell J.H.","Gu Z.","Guan P.","Harris M.","Harris N.L.","Harvey D.A.","Heiman T.J.","Hernandez J.R.","Houck J.","Hostin D.","Houston K.A.","Howland T.J.","Wei M.-H.","Ibegwam C.","Jalali M.","Kalush F.","Karpen G.H.","Ke Z.","Kennison J.A.","Ketchum K.A.","Kimmel B.E.","Kodira C.D.","Kraft C.L.","Kravitz S.","Kulp D.","Lai Z.","Lasko P.","Lei Y.","Levitsky A.A.","Li J.H.","Li Z.","Liang Y.","Lin X.","Liu X.","Mattei B.","McIntosh T.C.","McLeod M.P.","McPherson D.","Merkulov G.","Milshina N.V.","Mobarry C.","Morris J.","Moshrefi A.","Mount S.M.","Moy M.","Murphy B.","Murphy L.","Muzny D.M.","Nelson D.L.","Nelson D.R.","Nelson K.A.","Nixon K.","Nusskern D.R.","Pacleb J.M.","Palazzolo M.","Pittman G.S.","Pan S.","Pollard J.","Puri V.","Reese M.G.","Reinert K.","Remington K.","Saunders R.D.C.","Scheeler F.","Shen H.","Shue B.C.","Siden-Kiamos I.","Simpson M.","Skupski M.P.","Smith T.J.","Spier E.","Spradling A.C.","Stapleton M.","Strong R.","Sun E.","Svirskas R.","Tector C.","Turner R.","Venter E.","Wang A.H.","Wang X.","Wang Z.-Y.","Wassarman D.A.","Weinstock G.M.","Weissenbach J.","Williams S.M.","Woodage T.","Worley K.C.","Wu D.","Yang S.","Yao Q.A.","Ye J.","Yeh R.-F.","Zaveri J.S.","Zhan M.","Zhang G.","Zhao Q.","Zheng L.","Zheng X.H.","Zhong F.N.","Zhong W.","Zhou X.","Zhu S.C.","Zhu X.","Smith H.O.","Gibbs R.A.","Myers E.W.","Rubin G.M.","Venter J.C."],"citationCrossReferences":[{"database":"PubMed","id":"10731132"},{"database":"DOI","id":"10.1126/science.287.5461.2185"}],"title":"The genome sequence of Drosophila melanogaster.","publicationDate":"2000","journal":"Science","firstPage":"2185","lastPage":"2195","volume":"287"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"Berkeley","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"12537572","citationType":"journal article","authors":["Misra S.","Crosby M.A.","Mungall C.J.","Matthews B.B.","Campbell K.S.","Hradecky P.","Huang Y.","Kaminker J.S.","Millburn G.H.","Prochnik S.E.","Smith C.D.","Tupy J.L.","Whitfield E.J.","Bayraktaroglu L.","Berman B.P.","Bettencourt B.R.","Celniker S.E.","de Grey A.D.N.J.","Drysdale R.A.","Harris N.L.","Richter J.","Russo S.","Schroeder A.J.","Shu S.Q.","Stapleton M.","Yamada C.","Ashburner M.","Gelbart W.M.","Rubin G.M.","Lewis S.E."],"citationCrossReferences":[{"database":"PubMed","id":"12537572"},{"database":"DOI","id":"10.1186/gb-2002-3-12-research0083"}],"title":"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.","publicationDate":"2002","journal":"Genome Biol.","firstPage":"RESEARCH0083.1","lastPage":"RESEARCH0083.22","volume":"3"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"Berkeley","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"12537569","citationType":"journal article","authors":["Stapleton M.","Carlson J.W.","Brokstein P.","Yu C.","Champe M.","George R.A.","Guarin H.","Kronmiller B.","Pacleb J.M.","Park S.","Wan K.H.","Rubin G.M.","Celniker S.E."],"citationCrossReferences":[{"database":"PubMed","id":"12537569"},{"database":"DOI","id":"10.1186/gb-2002-3-12-research0080"}],"title":"A Drosophila full-length cDNA resource.","publicationDate":"2002","journal":"Genome Biol.","firstPage":"RESEARCH0080.1","lastPage":"RESEARCH0080.8","volume":"3"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Berkeley","type":"STRAIN"},{"value":"Testis","type":"TISSUE"}]},{"referenceNumber":5,"citation":{"id":"27646273","citationType":"journal article","authors":["Vieillard J.","Paschaki M.","Duteyrat J.L.","Augiere C.","Cortier E.","Lapart J.A.","Thomas J.","Durand B."],"citationCrossReferences":[{"database":"PubMed","id":"27646273"},{"database":"DOI","id":"10.1083/jcb.201603086"}],"title":"Transition zone assembly and its contribution to axoneme formation in Drosophila male germ cells.","publicationDate":"2016","journal":"J. Cell Biol.","firstPage":"875","lastPage":"889","volume":"214"},"referencePositions":["FUNCTION","IDENTIFICATION IN THE MKS COMPLEX","SUBCELLULAR LOCATION","TISSUE SPECIFICITY","DISRUPTION PHENOTYPE"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ278873","properties":[{"key":"ProteinId","value":"ABB90565.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AE014134","properties":[{"key":"ProteinId","value":"AAF52348.3"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY118708","properties":[{"key":"ProteinId","value":"AAM50568.1"},{"key":"Status","value":"ALT_TERM"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"RefSeq","id":"NP_608998.2","properties":[{"key":"NucleotideSequenceId","value":"NM_135154.3"}]},{"database":"AlphaFoldDB","id":"Q9VMH0","properties":[{"key":"Description","value":"-"}]},{"database":"ComplexPortal","id":"CPX-2339","properties":[{"key":"EntryName","value":"MKS complex"}]},{"database":"FunCoup","id":"Q9VMH0","properties":[{"key":"Number of interactors","value":"61"}]},{"database":"IntAct","id":"Q9VMH0","properties":[{"key":"Interactions","value":"1"}]},{"database":"STRING","id":"7227.FBpp0292198","properties":[{"key":"Description","value":"-"}]},{"database":"GlyCosmos","id":"Q9VMH0","properties":[{"key":"glycosylation","value":"10 sites, No reported glycans"}]},{"database":"GlyGen","id":"Q9VMH0","properties":[{"key":"glycosylation","value":"11 sites"}]},{"database":"PaxDb","id":"7227-FBpp0292198","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q9VMH0","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblMetazoa","id":"FBtr0303079","properties":[{"key":"ProteinId","value":"FBpp0292198"},{"key":"GeneId","value":"FBgn0261697"}]},{"database":"GeneID","id":"33866","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"dme:Dmel_CG42731","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"CG9227-RA","properties":[{"key":"OrganismName","value":"d. melanogaster"}]},{"database":"AGR","id":"FB:FBgn0261697","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"33866","properties":[{"key":"Description","value":"-"}]},{"database":"FlyBase","id":"FBgn0261697","properties":[{"key":"GeneName","value":"tctn"}]},{"database":"VEuPathDB","id":"VectorBase:FBgn0261697","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG4028","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_018942_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q9VMH0","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"DFQYNHG","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"2104337at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"Q9VMH0","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID-ORCS","id":"33866","properties":[{"key":"hits","value":"0 hits in 3 CRISPR screens"}]},{"database":"GenomeRNAi","id":"33866","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:Q9VMH0","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000803","properties":[{"key":"Component","value":"Chromosome 2L"}]},{"database":"Bgee","id":"FBgn0261697","properties":[{"key":"ExpressionPatterns","value":"Expressed in imaginal disc and 1 other cell type or tissue"}]},{"database":"GO","id":"GO:0005814","properties":[{"key":"GoTerm","value":"C:centriole"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0035869","properties":[{"key":"GoTerm","value":"C:ciliary transition zone"},{"key":"GoEvidenceType","value":"IDA:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"27577095"},{"evidenceCode":"ECO:0000314","source":"PubMed","id":"27646273"}]},{"database":"GO","id":"GO:0005576","properties":[{"key":"GoTerm","value":"C:extracellular region"},{"key":"GoEvidenceType","value":"ISS:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000250","source":"PubMed","id":"16357211"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0036038","properties":[{"key":"GoTerm","value":"C:MKS complex"},{"key":"GoEvidenceType","value":"ISS:FlyBase"}]},{"database":"GO","id":"GO:1905349","properties":[{"key":"GoTerm","value":"P:ciliary transition zone assembly"},{"key":"GoEvidenceType","value":"NAS:ComplexPortal"}],"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"27577095"}]},{"database":"GO","id":"GO:0060271","properties":[{"key":"GoTerm","value":"P:cilium assembly"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0007288","properties":[{"key":"GoTerm","value":"P:sperm axoneme assembly"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"27646273"}]},{"database":"GO","id":"GO:1905350","properties":[{"key":"GoTerm","value":"P:Y-shaped link assembly"},{"key":"GoEvidenceType","value":"NAS:ComplexPortal"}],"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"27577095"}]},{"database":"InterPro","id":"IPR040354","properties":[{"key":"EntryName","value":"TCTN1-3"}]},{"database":"InterPro","id":"IPR011677","properties":[{"key":"EntryName","value":"TCTN1-3_dom"}]},{"database":"InterPro","id":"IPR057724","properties":[{"key":"EntryName","value":"TCTN1-3_N"}]},{"database":"PANTHER","id":"PTHR14611:SF2","properties":[{"key":"EntryName","value":"TECTONIC"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR14611","properties":[{"key":"EntryName","value":"TECTONIC FAMILY MEMBER"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF25752","properties":[{"key":"EntryName","value":"DUF1619_N"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07773","properties":[{"key":"EntryName","value":"TCTN_DUF1619"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKEVLPLVVLCLATYHTHSIKIGISHNYNATISPTASTTTEAPATTGAPSSETVSSISTLPEAEVTTTTPAITFPPRVQQKPKVAVASPTMSTALPLNSTEVNSTLSVSGDNTFYYCSCDLQAGRCDLNCCCDNDCPLETRQVFNCLPNSLLPQLESRLEDFQYTHGLPTCQINDGWLCVFRSNTKATKTQPPDMNIDTSQYRKWKDNLEYQESDYAQSRPSAGHYKFGQTLQLWQPETKQLATLELPAAYESPNCQLKQSVWHLQPIRHVCRMKDSAQLQESIWSLLNQTSNYEILSKPRDLEEPEVNGLIVQVCLRGANKSMRCLERGNDTQLDVIVDHVELQLIHNFTNILEAKLFLEEAKLAEDDNEPLWLRYNVEFVTLNESLTKPTSGPLGYLSGAPVILSRMLPQNSSEDKQLISYHSLNQNIKEFHWLSLPSRKPRGSSCQRALDHKEALRFGIDLLTRCELRHAAPLLQAHANHTEYCQGLQAQIWSLLLPHNCTQLEDVTKVFVSHLGRPQPDKWLPMEVRYPENVHEMPPPVQAVYDEMRQSLSCRNIFLSVGYEFHVAHLAMVEGRAPHQRVLQHARLVLGQRHDLEFDTSEIEVALPLSISAMFYRMQTKALSNGAAVGIAGHLVLVEMIYLGIIYLGSMQLCL","length":657,"molWeight":73933,"crc64":"2CC74D54592EABB0","md5":"2E0802DD77345F857A5336CCF742DB84"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"TISSUE SPECIFICITY":1,"DISRUPTION PHENOTYPE":1,"SIMILARITY":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Signal":1,"Chain":1,"Topological domain":2,"Transmembrane":1,"Region":1,"Compositional bias":1,"Glycosylation":10,"Sequence conflict":10},"uniParcId":"UPI00004835F6"}}