{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q9V4P1","secondaryAccessions":["Q24240","Q8MKN2","Q8T067"],"uniProtkbId":"ANLN_DROME","entryAudit":{"firstPublicDate":"2006-03-21","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2002-10-01","entryVersion":172,"sequenceVersion":3},"annotationScore":5.0,"organism":{"scientificName":"Drosophila melanogaster","commonName":"Fruit fly","taxonId":7227,"lineage":["Eukaryota","Metazoa","Ecdysozoa","Arthropoda","Altocrustacea","Allotriocarida","Hexapoda","Insecta","Pterygota","Neoptera","Eumetabola","Endopterygota","Aparaglossata","Panorpida","Diptera","Brachycera","Muscomorpha","Ephydroidea","Drosophilidae","Drosophila","Sophophora"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Anillin"}},"alternativeNames":[{"fullName":{"value":"Actin-binding protein 8"},"shortNames":[{"value":"ABP8"}]},{"fullName":{"value":"Protein scraps"}}]},"genes":[{"geneName":{"value":"scra"},"synonyms":[{"value":"ani"}],"orfNames":[{"value":"CG2092"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"12134082"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"14736750"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"15380073"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"15496454"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"15930114"}],"value":"Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression and proper formation of the midbody. Required during cellularization of syncytial embryos for the proper formation and function of the furrow canals, the stable inward folds of the plasma membrane which separate the peripheral nuclei. Also required for the formation of the pole cells, the progenitors of the adult germline which are formed by cytokinesis of the cytoplasmic buds at the posterior pole of the syncytial embryo. Essential for embryonic viability"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"7559773"}],"value":"Interacts with and bundles F-actin"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"20237161"}],"value":"Mainly found in the nucleus during interphase. Colocalizes with cortical F-actin upon nuclear envelope breakdown in mitosis and subsequently concentrates in the area of the prospective contractile ring in anaphase. This pattern persists until telophase, when the protein becomes concentrated in the midbody. Accumulates in the nucleus of newly divided cells in a diffuse staining pattern, thereby restarting the cycle. Localizes to ring canal structures at the growing end of elongating spermatid cysts (PubMed:20237161)"}]},"subcellularLocations":[{"location":{"value":"Nucleus","id":"SL-0191"}},{"location":{"value":"Cytoplasm, cytoskeleton","id":"SL-0090"}},{"location":{"value":"Cytoplasm, cell cortex","id":"SL-0138"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"20237161"}],"value":"Cell projection, cilium, flagellum","id":"SL-0117"}}]},{"commentType":"ALTERNATIVE PRODUCTS","events":["Alternative splicing"],"isoforms":[{"name":{"value":"B"},"isoformIds":["Q9V4P1-1"],"isoformSequenceStatus":"Displayed"},{"name":{"value":"A"},"isoformIds":["Q9V4P1-2"],"sequenceIds":["VSP_017618"],"isoformSequenceStatus":"Described"}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10381388"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"12538517"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9013326"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9655801"}],"value":"Accumulates in the ring canals that interconnect cells of the germline cysts in males and the ovarian follicles in females. These structures develop from arrested contractile rings after a specialized cytokinesis in which the closing of the invaginating plasma membrane is incomplete. Also concentrates in the arrested cleavage furrows that initially link the oocyte to its 15 nurse cells in the early egg chamber and is subsequently lost from these furrows as germline cell division is completed"}],"commentType":"TISSUE SPECIFICITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10751177"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"14736750"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"20237161"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"7559773"}],"value":"Expressed in elongating spermatid cysts during spermatogenesis (at protein level) (PubMed:20237161). Expressed throughout development and at reduced levels late in embryogenesis. Localizes to the embryonic cortex and to the metaphase furrows which separate mitotic nuclei in the syncytial embryo prior to cellularization. Concentrates in the leading edges of the furrow canals at the onset of cellularization"}],"commentType":"DEVELOPMENTAL STAGE"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1239,"modifier":"EXACT"}},"description":"Anillin","featureId":"PRO_0000227968"},{"type":"Domain","location":{"start":{"value":1106,"modifier":"EXACT"},"end":{"value":1230,"modifier":"EXACT"}},"description":"PH","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00145"}]},{"type":"Region","location":{"start":{"value":32,"modifier":"EXACT"},"end":{"value":67,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":126,"modifier":"EXACT"},"end":{"value":371,"modifier":"EXACT"}},"description":"Interaction with and bundling of F-actin"},{"type":"Region","location":{"start":{"value":230,"modifier":"EXACT"},"end":{"value":265,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":493,"modifier":"EXACT"},"end":{"value":621,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":684,"modifier":"EXACT"},"end":{"value":716,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Coiled coil","location":{"start":{"value":834,"modifier":"EXACT"},"end":{"value":861,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Compositional bias","location":{"start":{"value":53,"modifier":"EXACT"},"end":{"value":63,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":252,"modifier":"EXACT"},"end":{"value":265,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":500,"modifier":"EXACT"},"end":{"value":518,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":519,"modifier":"EXACT"},"end":{"value":528,"modifier":"EXACT"}},"description":"Pro residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":551,"modifier":"EXACT"},"end":{"value":563,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":594,"modifier":"EXACT"},"end":{"value":610,"modifier":"EXACT"}},"description":"Acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":699,"modifier":"EXACT"},"end":{"value":716,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Modified residue","location":{"start":{"value":712,"modifier":"EXACT"},"end":{"value":712,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"18327897"}]},{"type":"Modified residue","location":{"start":{"value":740,"modifier":"EXACT"},"end":{"value":740,"modifier":"EXACT"}},"description":"Phosphothreonine","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"18327897"}]},{"type":"Modified residue","location":{"start":{"value":744,"modifier":"EXACT"},"end":{"value":744,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"18327897"}]},{"type":"Modified residue","location":{"start":{"value":754,"modifier":"EXACT"},"end":{"value":754,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"18327897"}]},{"type":"Modified residue","location":{"start":{"value":831,"modifier":"EXACT"},"end":{"value":831,"modifier":"EXACT"}},"description":"Phosphothreonine","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"18327897"}]},{"type":"Alternative sequence","location":{"start":{"value":272,"modifier":"EXACT"},"end":{"value":298,"modifier":"EXACT"}},"description":"in isoform A","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"7559773"}],"featureId":"VSP_017618","alternativeSequence":{}},{"type":"Mutagenesis","location":{"start":{"value":549,"modifier":"EXACT"},"end":{"value":549,"modifier":"EXACT"}},"description":"In allele scra3. Weak maternal effect allele; abrogates separation of pole cells.","alternativeSequence":{"originalSequence":"T","alternativeSequences":["I"]}},{"type":"Mutagenesis","location":{"start":{"value":1107,"modifier":"EXACT"},"end":{"value":1107,"modifier":"EXACT"}},"description":"In alleles scra1; scra3; scra4; and scra5.","alternativeSequence":{"originalSequence":"V","alternativeSequences":["S"]}},{"type":"Mutagenesis","location":{"start":{"value":1114,"modifier":"EXACT"},"end":{"value":1114,"modifier":"EXACT"}},"description":"In allele scra5. Strong maternal effect allele; abrogates cellularization of syncytial embryos.","alternativeSequence":{"originalSequence":"T","alternativeSequences":["I"]}},{"type":"Mutagenesis","location":{"start":{"value":1121,"modifier":"EXACT"},"end":{"value":1121,"modifier":"EXACT"}},"description":"In allele scra1. Strong maternal effect allele; abrogates cellularization of syncytial embryos.","alternativeSequence":{"originalSequence":"G","alternativeSequences":["E"]}},{"type":"Mutagenesis","location":{"start":{"value":1143,"modifier":"EXACT"},"end":{"value":1143,"modifier":"EXACT"}},"description":"In allele scra4. Strong maternal effect allele; abrogates cellularization of syncytial embryos.","alternativeSequence":{"originalSequence":"P","alternativeSequences":["S"]}},{"type":"Sequence conflict","location":{"start":{"value":38,"modifier":"EXACT"},"end":{"value":40,"modifier":"EXACT"}},"description":"in Ref. 1; CAA61954","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{}},{"type":"Sequence conflict","location":{"start":{"value":50,"modifier":"EXACT"},"end":{"value":60,"modifier":"EXACT"}},"description":"in Ref. 1; CAA61954","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"LAPRSRSPGGQ","alternativeSequences":["PAP"]}},{"type":"Sequence conflict","location":{"start":{"value":228,"modifier":"EXACT"},"end":{"value":228,"modifier":"EXACT"}},"description":"in Ref. 1; CAA61954","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"L","alternativeSequences":["P"]}},{"type":"Sequence conflict","location":{"start":{"value":394,"modifier":"EXACT"},"end":{"value":394,"modifier":"EXACT"}},"description":"in Ref. 1; CAA61954","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"G","alternativeSequences":["A"]}},{"type":"Sequence conflict","location":{"start":{"value":426,"modifier":"EXACT"},"end":{"value":426,"modifier":"EXACT"}},"description":"in Ref. 1; CAA61954","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"M","alternativeSequences":["V"]}},{"type":"Sequence conflict","location":{"start":{"value":689,"modifier":"EXACT"},"end":{"value":689,"modifier":"EXACT"}},"description":"in Ref. 1; CAA61954","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"D","alternativeSequences":["E"]}}],"keywords":[{"id":"KW-0009","category":"Molecular function","name":"Actin-binding"},{"id":"KW-0025","category":"Coding sequence diversity","name":"Alternative splicing"},{"id":"KW-0131","category":"Biological process","name":"Cell cycle"},{"id":"KW-0132","category":"Biological process","name":"Cell division"},{"id":"KW-0966","category":"Cellular component","name":"Cell projection"},{"id":"KW-0969","category":"Cellular component","name":"Cilium"},{"id":"KW-0175","category":"Domain","name":"Coiled coil"},{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0206","category":"Cellular component","name":"Cytoskeleton"},{"id":"KW-0217","category":"Molecular function","name":"Developmental protein"},{"id":"KW-0221","category":"Biological process","name":"Differentiation"},{"id":"KW-0282","category":"Cellular component","name":"Flagellum"},{"id":"KW-0469","category":"Biological process","name":"Meiosis"},{"id":"KW-0498","category":"Biological process","name":"Mitosis"},{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-0896","category":"Biological process","name":"Oogenesis"},{"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0744","category":"Biological process","name":"Spermatogenesis"}],"references":[{"referenceNumber":1,"citation":{"id":"7559773","citationType":"journal article","authors":["Field C.M.","Alberts B.M."],"citationCrossReferences":[{"database":"PubMed","id":"7559773"},{"database":"DOI","id":"10.1083/jcb.131.1.165"}],"title":"Anillin, a contractile ring protein that cycles from the nucleus to the cell cortex.","publicationDate":"1995","journal":"J. Cell Biol.","firstPage":"165","lastPage":"178","volume":"131"},"referencePositions":["NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A)","INTERACTION WITH ACTIN","SUBCELLULAR LOCATION","DEVELOPMENTAL STAGE"],"referenceComments":[{"value":"Embryo","type":"TISSUE"}]},{"referenceNumber":2,"citation":{"id":"10731132","citationType":"journal article","authors":["Adams M.D.","Celniker S.E.","Holt R.A.","Evans C.A.","Gocayne J.D.","Amanatides P.G.","Scherer S.E.","Li P.W.","Hoskins R.A.","Galle R.F.","George R.A.","Lewis S.E.","Richards S.","Ashburner M.","Henderson S.N.","Sutton G.G.","Wortman J.R.","Yandell M.D.","Zhang Q.","Chen L.X.","Brandon R.C.","Rogers Y.-H.C.","Blazej R.G.","Champe M.","Pfeiffer B.D.","Wan K.H.","Doyle C.","Baxter E.G.","Helt G.","Nelson C.R.","Miklos G.L.G.","Abril J.F.","Agbayani A.","An H.-J.","Andrews-Pfannkoch C.","Baldwin D.","Ballew R.M.","Basu A.","Baxendale J.","Bayraktaroglu L.","Beasley E.M.","Beeson K.Y.","Benos P.V.","Berman B.P.","Bhandari D.","Bolshakov S.","Borkova D.","Botchan M.R.","Bouck J.","Brokstein P.","Brottier P.","Burtis K.C.","Busam D.A.","Butler H.","Cadieu E.","Center A.","Chandra I.","Cherry J.M.","Cawley S.","Dahlke C.","Davenport L.B.","Davies P.","de Pablos B.","Delcher A.","Deng Z.","Mays A.D.","Dew I.","Dietz S.M.","Dodson K.","Doup L.E.","Downes M.","Dugan-Rocha S.","Dunkov B.C.","Dunn P.","Durbin K.J.","Evangelista C.C.","Ferraz C.","Ferriera S.","Fleischmann W.","Fosler C.","Gabrielian A.E.","Garg N.S.","Gelbart W.M.","Glasser K.","Glodek A.","Gong F.","Gorrell J.H.","Gu Z.","Guan P.","Harris M.","Harris N.L.","Harvey D.A.","Heiman T.J.","Hernandez J.R.","Houck J.","Hostin D.","Houston K.A.","Howland T.J.","Wei M.-H.","Ibegwam C.","Jalali M.","Kalush F.","Karpen G.H.","Ke Z.","Kennison J.A.","Ketchum K.A.","Kimmel B.E.","Kodira C.D.","Kraft C.L.","Kravitz S.","Kulp D.","Lai Z.","Lasko P.","Lei Y.","Levitsky A.A.","Li J.H.","Li Z.","Liang Y.","Lin X.","Liu X.","Mattei B.","McIntosh T.C.","McLeod M.P.","McPherson D.","Merkulov G.","Milshina N.V.","Mobarry C.","Morris J.","Moshrefi A.","Mount S.M.","Moy M.","Murphy B.","Murphy L.","Muzny D.M.","Nelson D.L.","Nelson D.R.","Nelson K.A.","Nixon K.","Nusskern D.R.","Pacleb J.M.","Palazzolo M.","Pittman G.S.","Pan S.","Pollard J.","Puri V.","Reese M.G.","Reinert K.","Remington K.","Saunders R.D.C.","Scheeler F.","Shen H.","Shue B.C.","Siden-Kiamos I.","Simpson M.","Skupski M.P.","Smith T.J.","Spier E.","Spradling A.C.","Stapleton M.","Strong R.","Sun E.","Svirskas R.","Tector C.","Turner R.","Venter E.","Wang A.H.","Wang X.","Wang Z.-Y.","Wassarman D.A.","Weinstock G.M.","Weissenbach J.","Williams S.M.","Woodage T.","Worley K.C.","Wu D.","Yang S.","Yao Q.A.","Ye J.","Yeh R.-F.","Zaveri J.S.","Zhan M.","Zhang G.","Zhao Q.","Zheng L.","Zheng X.H.","Zhong F.N.","Zhong W.","Zhou X.","Zhu S.C.","Zhu X.","Smith H.O.","Gibbs R.A.","Myers E.W.","Rubin G.M.","Venter J.C."],"citationCrossReferences":[{"database":"PubMed","id":"10731132"},{"database":"DOI","id":"10.1126/science.287.5461.2185"}],"title":"The genome sequence of Drosophila melanogaster.","publicationDate":"2000","journal":"Science","firstPage":"2185","lastPage":"2195","volume":"287"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"Berkeley","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"12537572","citationType":"journal article","authors":["Misra S.","Crosby M.A.","Mungall C.J.","Matthews B.B.","Campbell K.S.","Hradecky P.","Huang Y.","Kaminker J.S.","Millburn G.H.","Prochnik S.E.","Smith C.D.","Tupy J.L.","Whitfield E.J.","Bayraktaroglu L.","Berman B.P.","Bettencourt B.R.","Celniker S.E.","de Grey A.D.N.J.","Drysdale R.A.","Harris N.L.","Richter J.","Russo S.","Schroeder A.J.","Shu S.Q.","Stapleton M.","Yamada C.","Ashburner M.","Gelbart W.M.","Rubin G.M.","Lewis S.E."],"citationCrossReferences":[{"database":"PubMed","id":"12537572"},{"database":"DOI","id":"10.1186/gb-2002-3-12-research0083"}],"title":"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.","publicationDate":"2002","journal":"Genome Biol.","firstPage":"RESEARCH0083.1","lastPage":"RESEARCH0083.22","volume":"3"},"referencePositions":["GENOME REANNOTATION","ALTERNATIVE SPLICING"],"referenceComments":[{"value":"Berkeley","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"12537569","citationType":"journal article","authors":["Stapleton M.","Carlson J.W.","Brokstein P.","Yu C.","Champe M.","George R.A.","Guarin H.","Kronmiller B.","Pacleb J.M.","Park S.","Wan K.H.","Rubin G.M.","Celniker S.E."],"citationCrossReferences":[{"database":"PubMed","id":"12537569"},{"database":"DOI","id":"10.1186/gb-2002-3-12-research0080"}],"title":"A Drosophila full-length cDNA resource.","publicationDate":"2002","journal":"Genome Biol.","firstPage":"RESEARCH0080.1","lastPage":"RESEARCH0080.8","volume":"3"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B)"],"referenceComments":[{"value":"Berkeley","type":"STRAIN"},{"value":"Embryo","type":"TISSUE"}]},{"referenceNumber":5,"citation":{"id":"9013326","citationType":"journal article","authors":["Hime G.R.","Brill J.A.","Fuller M.T."],"citationCrossReferences":[{"database":"PubMed","id":"9013326"},{"database":"DOI","id":"10.1242/jcs.109.12.2779"}],"title":"Assembly of ring canals in the male germ line from structural components of the contractile ring.","publicationDate":"1996","journal":"J. Cell Sci.","firstPage":"2779","lastPage":"2788","volume":"109"},"referencePositions":["SUBCELLULAR LOCATION","TISSUE SPECIFICITY"]},{"referenceNumber":6,"citation":{"id":"9477328","citationType":"journal article","authors":["Rothwell W.F.","Fogarty P.","Field C.M.","Sullivan W."],"citationCrossReferences":[{"database":"PubMed","id":"9477328"},{"database":"DOI","id":"10.1242/dev.125.7.1295"}],"title":"Nuclear-fallout, a Drosophila protein that cycles from the cytoplasm to the centrosomes, regulates cortical microfilament organization.","publicationDate":"1998","journal":"Development","firstPage":"1295","lastPage":"1303","volume":"125"},"referencePositions":["SUBCELLULAR LOCATION"]},{"referenceNumber":7,"citation":{"id":"9655801","citationType":"journal article","authors":["de Cuevas M.","Spradling A.C."],"citationCrossReferences":[{"database":"PubMed","id":"9655801"},{"database":"DOI","id":"10.1242/dev.125.15.2781"}],"title":"Morphogenesis of the Drosophila fusome and its implications for oocyte specification.","publicationDate":"1998","journal":"Development","firstPage":"2781","lastPage":"2789","volume":"125"},"referencePositions":["SUBCELLULAR LOCATION","TISSUE SPECIFICITY"]},{"referenceNumber":8,"citation":{"id":"10381388","citationType":"journal article","authors":["Giansanti M.G.","Bonaccorsi S.","Gatti M."],"citationCrossReferences":[{"database":"PubMed","id":"10381388"},{"database":"DOI","id":"10.1242/jcs.112.14.2323"}],"title":"The role of anillin in meiotic cytokinesis of Drosophila males.","publicationDate":"1999","journal":"J. Cell Sci.","firstPage":"2323","lastPage":"2334","volume":"112"},"referencePositions":["SUBCELLULAR LOCATION","TISSUE SPECIFICITY"]},{"referenceNumber":9,"citation":{"id":"10444383","citationType":"journal article","authors":["Rothwell W.F.","Zhang C.X.","Zelano C.","Hsieh T.-S.","Sullivan W."],"citationCrossReferences":[{"database":"PubMed","id":"10444383"},{"database":"DOI","id":"10.1242/jcs.112.17.2885"}],"title":"The Drosophila centrosomal protein Nuf is required for recruiting Dah, a membrane associated protein, to furrows in the early embryo.","publicationDate":"1999","journal":"J. Cell Sci.","firstPage":"2885","lastPage":"2893","volume":"112"},"referencePositions":["SUBCELLULAR LOCATION"]},{"referenceNumber":10,"citation":{"id":"10751177","citationType":"journal article","authors":["Afshar K.","Stuart B.","Wasserman S.A."],"citationCrossReferences":[{"database":"PubMed","id":"10751177"},{"database":"DOI","id":"10.1242/dev.127.9.1887"}],"title":"Functional analysis of the Drosophila diaphanous FH protein in early embryonic development.","publicationDate":"2000","journal":"Development","firstPage":"1887","lastPage":"1897","volume":"127"},"referencePositions":["DEVELOPMENTAL STAGE"]},{"referenceNumber":11,"citation":{"id":"12134082","citationType":"journal article","authors":["Somma M.P.","Fasulo B.","Cenci G.","Cundari E.","Gatti M."],"citationCrossReferences":[{"database":"PubMed","id":"12134082"},{"database":"DOI","id":"10.1091/mbc.01-12-0589"}],"title":"Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells.","publicationDate":"2002","journal":"Mol. Biol. Cell","firstPage":"2448","lastPage":"2460","volume":"13"},"referencePositions":["FUNCTION","SUBCELLULAR LOCATION"]},{"referenceNumber":12,"citation":{"id":"12538517","citationType":"journal article","authors":["Mathe E.","Inoue Y.H.","Palframan W.","Brown G.","Glover D.M."],"citationCrossReferences":[{"database":"PubMed","id":"12538517"},{"database":"DOI","id":"10.1242/dev.00315"}],"title":"Orbit/Mast, the CLASP orthologue of Drosophila, is required for asymmetric stem cell and cystocyte divisions and development of the polarised microtubule network that interconnects oocyte and nurse cells during oogenesis.","publicationDate":"2003","journal":"Development","firstPage":"901","lastPage":"915","volume":"130"},"referencePositions":["SUBCELLULAR LOCATION","TISSUE SPECIFICITY"]},{"referenceNumber":13,"citation":{"id":"15380073","citationType":"journal article","authors":["Echard A.","Hickson G.R.X.","Foley E.","O'Farrell P.H."],"citationCrossReferences":[{"database":"PubMed","id":"15380073"},{"database":"DOI","id":"10.1016/j.cub.2004.08.063"}],"title":"Terminal cytokinesis events uncovered after an RNAi screen.","publicationDate":"2004","journal":"Curr. Biol.","firstPage":"1685","lastPage":"1693","volume":"14"},"referencePositions":["FUNCTION","SUBCELLULAR LOCATION"]},{"referenceNumber":14,"citation":{"id":"14736750","citationType":"journal article","authors":["Thomas J.H.","Wieschaus E."],"citationCrossReferences":[{"database":"PubMed","id":"14736750"},{"database":"DOI","id":"10.1242/dev.00989"}],"title":"src64 and tec29 are required for microfilament contraction during Drosophila cellularization.","publicationDate":"2004","journal":"Development","firstPage":"863","lastPage":"871","volume":"131"},"referencePositions":["FUNCTION","SUBCELLULAR LOCATION","DEVELOPMENTAL STAGE"]},{"referenceNumber":15,"citation":{"id":"15240570","citationType":"journal article","authors":["D'Avino P.P.","Savoian M.S.","Glover D.M."],"citationCrossReferences":[{"database":"PubMed","id":"15240570"},{"database":"DOI","id":"10.1083/jcb.200402157"}],"title":"Mutations in sticky lead to defective organization of the contractile ring during cytokinesis and are enhanced by Rho and suppressed by Rac.","publicationDate":"2004","journal":"J. Cell Biol.","firstPage":"61","lastPage":"71","volume":"166"},"referencePositions":["SUBCELLULAR LOCATION"]},{"referenceNumber":16,"citation":{"id":"15004238","citationType":"journal article","authors":["Giansanti M.G.","Farkas R.M.","Bonaccorsi S.","Lindsley D.L.","Wakimoto B.T.","Fuller M.T.","Gatti M."],"citationCrossReferences":[{"database":"PubMed","id":"15004238"},{"database":"DOI","id":"10.1091/mbc.e03-08-0603"}],"title":"Genetic dissection of meiotic cytokinesis in Drosophila males.","publicationDate":"2004","journal":"Mol. Biol. Cell","firstPage":"2509","lastPage":"2522","volume":"15"},"referencePositions":["SUBCELLULAR LOCATION"]},{"referenceNumber":17,"citation":{"id":"15371536","citationType":"journal article","authors":["Naim V.","Imarisio S.","Di Cunto F.","Gatti M.","Bonaccorsi S."],"citationCrossReferences":[{"database":"PubMed","id":"15371536"},{"database":"DOI","id":"10.1091/mbc.e04-06-0536"}],"title":"Drosophila citron kinase is required for the final steps of cytokinesis.","publicationDate":"2004","journal":"Mol. Biol. Cell","firstPage":"5053","lastPage":"5063","volume":"15"},"referencePositions":["SUBCELLULAR LOCATION"]},{"referenceNumber":18,"citation":{"id":"15930114","citationType":"journal article","authors":["Field C.M.","Coughlin M.","Doberstein S.","Marty T.","Sullivan W."],"citationCrossReferences":[{"database":"PubMed","id":"15930114"},{"database":"DOI","id":"10.1242/dev.01843"}],"title":"Characterization of anillin mutants reveals essential roles in septin localization and plasma membrane integrity.","publicationDate":"2005","journal":"Development","firstPage":"2849","lastPage":"2860","volume":"132"},"referencePositions":["FUNCTION","SUBCELLULAR LOCATION","CHARACTERIZATION OF MUTANTS ILE-549; SER-1107; ILE-1114; GLU-1121 AND SER-1143"]},{"referenceNumber":19,"citation":{"id":"16280552","citationType":"journal article","authors":["Zavortink M.","Contreras N.","Addy T.","Bejsovec A.","Saint R."],"citationCrossReferences":[{"database":"PubMed","id":"16280552"},{"database":"DOI","id":"10.1242/jcs.02652"}],"title":"Tum/RacGAP50C provides a critical link between anaphase microtubules and the assembly of the contractile ring in Drosophila melanogaster.","publicationDate":"2005","journal":"J. Cell Sci.","firstPage":"5381","lastPage":"5392","volume":"118"},"referencePositions":["SUBCELLULAR LOCATION"]},{"referenceNumber":20,"citation":{"id":"15496454","citationType":"journal article","authors":["Straight A.F.","Field C.M.","Mitchison T.J."],"citationCrossReferences":[{"database":"PubMed","id":"15496454"},{"database":"DOI","id":"10.1091/mbc.e04-08-0758"}],"title":"Anillin binds nonmuscle myosin II and regulates the contractile ring.","publicationDate":"2005","journal":"Mol. Biol. Cell","firstPage":"193","lastPage":"201","volume":"16"},"referencePositions":["FUNCTION","SUBCELLULAR LOCATION"]},{"referenceNumber":21,"citation":{"id":"18327897","citationType":"journal article","authors":["Zhai B.","Villen J.","Beausoleil S.A.","Mintseris J.","Gygi S.P."],"citationCrossReferences":[{"database":"PubMed","id":"18327897"},{"database":"DOI","id":"10.1021/pr700696a"}],"title":"Phosphoproteome analysis of Drosophila melanogaster embryos.","publicationDate":"2008","journal":"J. Proteome Res.","firstPage":"1675","lastPage":"1682","volume":"7"},"referencePositions":["PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-712; THR-740; SER-744; SER-754 AND THR-831","IDENTIFICATION BY MASS SPECTROMETRY"],"referenceComments":[{"value":"Embryo","type":"TISSUE"}]},{"referenceNumber":22,"citation":{"id":"20237161","citationType":"journal article","authors":["Fabian L.","Wei H.C.","Rollins J.","Noguchi T.","Blankenship J.T.","Bellamkonda K.","Polevoy G.","Gervais L.","Guichet A.","Fuller M.T.","Brill J.A."],"citationCrossReferences":[{"database":"PubMed","id":"20237161"},{"database":"DOI","id":"10.1091/mbc.e09-07-0582"}],"title":"Phosphatidylinositol 4,5-bisphosphate directs spermatid cell polarity and exocyst localization in Drosophila.","publicationDate":"2010","journal":"Mol. Biol. Cell","firstPage":"1546","lastPage":"1555","volume":"21"},"referencePositions":["SUBCELLULAR LOCATION","DEVELOPMENTAL STAGE"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"X89858","properties":[{"key":"ProteinId","value":"CAA61954.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AE013599","properties":[{"key":"ProteinId","value":"AAF59225.3"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AE013599","properties":[{"key":"ProteinId","value":"AAM71099.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY069520","properties":[{"key":"ProteinId","value":"AAL39665.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"PIR","id":"A57369","properties":[{"key":"EntryName","value":"A57369"}]},{"database":"RefSeq","id":"NP_724582.1","properties":[{"key":"NucleotideSequenceId","value":"NM_165543.2"}],"isoformId":"Q9V4P1-1"},{"database":"RefSeq","id":"NP_724583.1","properties":[{"key":"NucleotideSequenceId","value":"NM_165544.2"}],"isoformId":"Q9V4P1-2"},{"database":"AlphaFoldDB","id":"Q9V4P1","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q9V4P1","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"61572","properties":[{"key":"Interactions","value":"52"}]},{"database":"FunCoup","id":"Q9V4P1","properties":[{"key":"Number of interactors","value":"48"}]},{"database":"IntAct","id":"Q9V4P1","properties":[{"key":"Interactions","value":"41"}]},{"database":"STRING","id":"7227.FBpp0087986","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"Q9V4P1","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"7227-FBpp0087986","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q9V4P1","properties":[{"key":"Description","value":"-"}]},{"database":"DNASU","id":"35696","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblMetazoa","id":"FBtr0088912","properties":[{"key":"ProteinId","value":"FBpp0087986"},{"key":"GeneId","value":"FBgn0261385"}]},{"database":"GeneID","id":"35696","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"dme:Dmel_CG2092","properties":[{"key":"Description","value":"-"}]},{"database":"AGR","id":"FB:FBgn0261385","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"35696","properties":[{"key":"Description","value":"-"}]},{"database":"FlyBase","id":"FBgn0261385","properties":[{"key":"GeneName","value":"scra"}]},{"database":"VEuPathDB","id":"VectorBase:FBgn0261385","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG3640","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_008475_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q9V4P1","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"TMSIPPK","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"5915976at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"Q9V4P1","properties":[{"key":"Description","value":"-"}]},{"database":"Reactome","id":"R-DME-8980692","properties":[{"key":"PathwayName","value":"RHOA GTPase cycle"}]},{"database":"SignaLink","id":"Q9V4P1","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID-ORCS","id":"35696","properties":[{"key":"hits","value":"0 hits in 1 CRISPR screen"}]},{"database":"GenomeRNAi","id":"35696","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:Q9V4P1","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000803","properties":[{"key":"Component","value":"Chromosome 2R"}]},{"database":"Bgee","id":"FBgn0261385","properties":[{"key":"ExpressionPatterns","value":"Expressed in egg cell and 62 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"Q9V4P1","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0005826","properties":[{"key":"GoTerm","value":"C:actomyosin contractile ring"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"15496454"}]},{"database":"GO","id":"GO:0032154","properties":[{"key":"GoTerm","value":"C:cleavage furrow"},{"key":"GoEvidenceType","value":"IDA:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"10485851"},{"evidenceCode":"ECO:0000314","source":"PubMed","id":"28100664"},{"evidenceCode":"ECO:0000314","source":"PubMed","id":"33037125"}]},{"database":"GO","id":"GO:0070938","properties":[{"key":"GoTerm","value":"C:contractile ring"},{"key":"GoEvidenceType","value":"IDA:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"10485851"},{"evidenceCode":"ECO:0000314","source":"PubMed","id":"20237160"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IDA:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"7559773"}]},{"database":"GO","id":"GO:0045172","properties":[{"key":"GoTerm","value":"C:germline ring canal"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"9013326"}]},{"database":"GO","id":"GO:0035323","properties":[{"key":"GoTerm","value":"C:male germline ring canal"},{"key":"GoEvidenceType","value":"IDA:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"20237160"}]},{"database":"GO","id":"GO:0031514","properties":[{"key":"GoTerm","value":"C:motile cilium"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"9013326"}]},{"database":"GO","id":"GO:0003779","properties":[{"key":"GoTerm","value":"F:actin binding"},{"key":"GoEvidenceType","value":"IDA:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"11076973"},{"evidenceCode":"ECO:0000314","source":"PubMed","id":"7559773"}]},{"database":"GO","id":"GO:0051015","properties":[{"key":"GoTerm","value":"F:actin filament binding"},{"key":"GoEvidenceType","value":"IDA:WormBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"7559773"}]},{"database":"GO","id":"GO:0008017","properties":[{"key":"GoTerm","value":"F:microtubule binding"},{"key":"GoEvidenceType","value":"IDA:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"11076973"}]},{"database":"GO","id":"GO:0017022","properties":[{"key":"GoTerm","value":"F:myosin binding"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"15496454"}]},{"database":"GO","id":"GO:0000915","properties":[{"key":"GoTerm","value":"P:actomyosin contractile ring assembly"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"15930114"}]},{"database":"GO","id":"GO:0044837","properties":[{"key":"GoTerm","value":"P:actomyosin contractile ring organization"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"38728140"}]},{"database":"GO","id":"GO:0008356","properties":[{"key":"GoTerm","value":"P:asymmetric cell division"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"18295597"}]},{"database":"GO","id":"GO:0007349","properties":[{"key":"GoTerm","value":"P:cellularization"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"14736750"}]},{"database":"GO","id":"GO:0007105","properties":[{"key":"GoTerm","value":"P:cytokinesis, division site positioning"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"20237160"}]},{"database":"GO","id":"GO:0043063","properties":[{"key":"GoTerm","value":"P:intercellular bridge organization"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"20451383"}]},{"database":"GO","id":"GO:0008104","properties":[{"key":"GoTerm","value":"P:intracellular protein localization"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"15930114"}]},{"database":"GO","id":"GO:0030726","properties":[{"key":"GoTerm","value":"P:male germline ring canal formation"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"9013326"}]},{"database":"GO","id":"GO:0007112","properties":[{"key":"GoTerm","value":"P:male meiosis cytokinesis"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"20237160"}]},{"database":"GO","id":"GO:0000281","properties":[{"key":"GoTerm","value":"P:mitotic cytokinesis"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"15930114"}]},{"database":"GO","id":"GO:0007009","properties":[{"key":"GoTerm","value":"P:plasma membrane organization"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"15930114"}]},{"database":"GO","id":"GO:0007279","properties":[{"key":"GoTerm","value":"P:pole cell formation"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"15930114"}]},{"database":"GO","id":"GO:0032465","properties":[{"key":"GoTerm","value":"P:regulation of cytokinesis"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"15496454"}]},{"database":"GO","id":"GO:0007423","properties":[{"key":"GoTerm","value":"P:sensory organ development"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"18295597"}]},{"database":"GO","id":"GO:0045035","properties":[{"key":"GoTerm","value":"P:sensory organ precursor cell division"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"18295597"}]},{"database":"GO","id":"GO:0031106","properties":[{"key":"GoTerm","value":"P:septin ring organization"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"15930114"},{"evidenceCode":"ECO:0000315","source":"PubMed","id":"20237160"}]},{"database":"GO","id":"GO:0042060","properties":[{"key":"GoTerm","value":"P:wound healing"},{"key":"GoEvidenceType","value":"IMP:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"38728140"}]},{"database":"CDD","id":"cd01263","properties":[{"key":"EntryName","value":"PH_anillin"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.30.29.30:FF:000111","properties":[{"key":"EntryName","value":"anillin isoform X1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.30.29.30","properties":[{"key":"EntryName","value":"Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR012966","properties":[{"key":"EntryName","value":"AHD"}]},{"database":"InterPro","id":"IPR051364","properties":[{"key":"EntryName","value":"Cytokinesis/Rho-signaling"}]},{"database":"InterPro","id":"IPR011993","properties":[{"key":"EntryName","value":"PH-like_dom_sf"}]},{"database":"InterPro","id":"IPR037840","properties":[{"key":"EntryName","value":"PH_Anillin"}]},{"database":"InterPro","id":"IPR001849","properties":[{"key":"EntryName","value":"PH_domain"}]},{"database":"PANTHER","id":"PTHR21538:SF23","properties":[{"key":"EntryName","value":"ANILLIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR21538","properties":[{"key":"EntryName","value":"ANILLIN/RHOTEKIN RTKN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF08174","properties":[{"key":"EntryName","value":"Anillin"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00169","properties":[{"key":"EntryName","value":"PH"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00233","properties":[{"key":"EntryName","value":"PH"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF50729","properties":[{"key":"EntryName","value":"PH domain-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50003","properties":[{"key":"EntryName","value":"PH_DOMAIN"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDPFTQHMLEKAEQRSRALGISNASKFPLVECSVPSSSATSASGGDAGVLAPRSRSPGGQSAASGGGKVVTLGKATLEASPAKPLRHYTAVNKENLDMGIEINITTDKPIGVQVEIQEQEVTDDEEQAEGGALNPLLEAEPVNQPLARLRDTSRSRLQRMGALYSNTDDLSSPIHRTEGQFHVTTGEEEDCGNRSSRQPKQRLGKLAALADTINQWEDDTSHHEVHRLLEAPPPKPHLSSRRAEKGPAPLPPKKDEVDEASRTKQLKWDPKVLSSLEAQGFQRRESSTIKHTYDYAKQEEAAPASKVEDAVLTAKPPVPQKSTTVSQVAKNFASSAPAPKPAPAPAVSVKSGLVSGRAALFENKGTGGQSQGLRNQKDPCELSLKERMKLFETGNNKAMLPMAPIGSAPSITQIRAEEVKQHLAAMHPVTAAAATTVVAATKPKQENKLRDKVAALVANAQSSAETRIKDIDRQRQEDMQIISNRFNKQKELFDNQPSDSSVAAQARPPAPAPSRVVRPMPPPPPPPIAALSPGLASSKRRSPGDAPTTDEDSKRARKSHSDRLYPALSDLDSSGDNCCAAETASATDDSHQQDEEETESCMDESDDQSQTEDSSAGMCNGSLGREIMSAVQRNEVEMQQQQTGKKTVRYADQDMYYDDSSLNSSQVSAGIDDYLDEALVEDYGSTQDDQSDSGDEQNASRLSLGSKGTTASNSFSFRKNPASICTPIEEHHEMEMDLQTPLLSGAQPVKSELSVNQDNDNLVTLVHTVSFYRRQQSANSSNSTPVRKICREQQVMRSALAGDCHAKHRLEYDSPQQSDYVAAATDIADQTDEDDEEMQNAREVNDASQAQDKIKKLLSEVCKQQQVIGQASQALNLCAATVEFSGSTESVEGERYLLLATHRRQACLDEVQRLRVENSIRPVGAPKEKGLLTVKDITIPLRQEYVRKMASNNINGHHLVCLLKYNEHVLATKTVPTMPGLLSVKFPDVLQLNNVYADFRITLEIYGMLAQRDQLPHELKYHINLNKKGGIKTPKKKGGENRLVMPPVQSPAGPHVVRTPQLVQYGFAIFSLREIQRTTWTLTQVLGVSPLEGVVHMKVNCELSVSVEYKGFLTMFEDISGFGAWHRRWCYLNGSVINYWKYPDDEKRKTPMGSIDLNSCTSQKVTTAPRDICARLNTMLLECERPALETDQESLIIVPNGRTTTVRHLLSADTKEEREEWCAYLNKALTLLRAWGTTH","length":1239,"molWeight":136033,"crc64":"EAA58335AE139A24","md5":"3DFF783250D09257443C2CC267CF0083"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"ALTERNATIVE PRODUCTS":2,"TISSUE SPECIFICITY":1,"DEVELOPMENTAL STAGE":1},"countByFeatureType":{"Chain":1,"Domain":1,"Region":5,"Coiled coil":1,"Compositional bias":7,"Modified residue":5,"Alternative sequence":1,"Mutagenesis":5,"Sequence conflict":6},"uniParcId":"UPI000007FD14"}}