{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q9US55","uniProtkbId":"GLU2A_SCHPO","entryAudit":{"firstPublicDate":"2009-05-05","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2000-05-01","entryVersion":139,"sequenceVersion":1},"annotationScore":4.0,"organism":{"scientificName":"Schizosaccharomyces pombe (strain 972 / ATCC 24843)","commonName":"Fission yeast","taxonId":284812,"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Taphrinomycotina","Schizosaccharomycetes","Schizosaccharomycetales","Schizosaccharomycetaceae","Schizosaccharomyces"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P38138"}],"value":"Glucosidase 2 subunit alpha"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9774332"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9813085"}],"value":"3.2.1.207"}]},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P38138"}],"value":"Alpha-glucosidase II subunit alpha"}},{"fullName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"EMBL","id":"CAB65603.1"}],"value":"Glucosidase II gls2"}},{"fullName":{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P38138"}],"value":"Glucosidase II subunit alpha"}}],"flag":"Precursor"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"EMBL","id":"CAB65603.1"}],"value":"gls2"},"orfNames":[{"value":"SPAC1002.03c"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P38138"}],"value":"Catalytic subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"N(4)-(alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + H2O = N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + beta-D-glucose","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:56000"},{"database":"Rhea","id":"RHEA-COMP:14356"},{"database":"Rhea","id":"RHEA-COMP:14357"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:15903"},{"database":"ChEBI","id":"CHEBI:59080"},{"database":"ChEBI","id":"CHEBI:139493"}],"ecNumber":"3.2.1.207","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9774332"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9813085"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"N(4)-(alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + H2O = N(4)-(alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + beta-D-glucose","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:55996"},{"database":"Rhea","id":"RHEA-COMP:14355"},{"database":"Rhea","id":"RHEA-COMP:14357"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:15903"},{"database":"ChEBI","id":"CHEBI:59080"},{"database":"ChEBI","id":"CHEBI:59082"}],"ecNumber":"3.2.1.207","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9774332"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9813085"}]}},{"texts":[{"value":"Glycan metabolism; N-glycan metabolism"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P38138"}],"value":"Heterodimer of a catalytic subunit alpha (gls2) and a subunit beta (gtb1)"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16823372"}],"value":"Endoplasmic reticulum","id":"SL-0095"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9774332"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9813085"}],"value":"Gls2 and alg6 double mutant cells that transfer Man(9)GlcNAc(2) and that are unable to remove the glucose units as they lack gls2, grow at 37 degrees Celsius, but are characterized by swollen cells, displaying pear, lemon and round shapes and have, when grown at 28 degrees Celsius, a phenotype of growth and morphology almost identical to that of wild-type cells, indicating that facilitation of glycoprotein folding mediated by the interaction of calnexin and monoglucosylated oligosaccharides does not necessarily require cycles of reglucosylation and deglucosylation. The gls2 and alg6 double mutant cells grown in the absence of exogenous stress show an induction of the binding protein (BiP)-encoding mRNA. An incubation of intact gls2 and alg6 mutant cells with [(14)C]glucose for 15 minutes in the absence of 1-deoxynojirimycin (DNJ) leads to the production of protein-linked Glc(1)Man(9)GlcNAc(2), Man(9)GlcNAc(2) and Man(8)GlcNAc(2)"}],"commentType":"DISRUPTION PHENOTYPE"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255"}],"value":"Belongs to the glycosyl hydrolase 31 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":25,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Chain","location":{"start":{"value":26,"modifier":"EXACT"},"end":{"value":923,"modifier":"EXACT"}},"description":"Glucosidase 2 subunit alpha","featureId":"PRO_0000372782"},{"type":"Active site","location":{"start":{"value":524,"modifier":"EXACT"},"end":{"value":524,"modifier":"EXACT"}},"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q9C0Y4"}]},{"type":"Active site","location":{"start":{"value":527,"modifier":"EXACT"},"end":{"value":527,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q9C0Y4"}]},{"type":"Active site","location":{"start":{"value":600,"modifier":"EXACT"},"end":{"value":600,"modifier":"EXACT"}},"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q9C0Y4"}]},{"type":"Glycosylation","location":{"start":{"value":262,"modifier":"EXACT"},"end":{"value":262,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Glycosylation","location":{"start":{"value":563,"modifier":"EXACT"},"end":{"value":563,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""},{"type":"Glycosylation","location":{"start":{"value":822,"modifier":"EXACT"},"end":{"value":822,"modifier":"EXACT"}},"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}],"featureId":""}],"keywords":[{"id":"KW-0256","category":"Cellular component","name":"Endoplasmic reticulum"},{"id":"KW-0325","category":"PTM","name":"Glycoprotein"},{"id":"KW-0326","category":"Molecular function","name":"Glycosidase"},{"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"11859360","citationType":"journal article","authors":["Wood V.","Gwilliam R.","Rajandream M.A.","Lyne M.H.","Lyne R.","Stewart A.","Sgouros J.G.","Peat N.","Hayles J.","Baker S.G.","Basham D.","Bowman S.","Brooks K.","Brown D.","Brown S.","Chillingworth T.","Churcher C.M.","Collins M.","Connor R.","Cronin A.","Davis P.","Feltwell T.","Fraser A.","Gentles S.","Goble A.","Hamlin N.","Harris D.E.","Hidalgo J.","Hodgson G.","Holroyd S.","Hornsby T.","Howarth S.","Huckle E.J.","Hunt S.","Jagels K.","James K.D.","Jones L.","Jones M.","Leather S.","McDonald S.","McLean J.","Mooney P.","Moule S.","Mungall K.L.","Murphy L.D.","Niblett D.","Odell C.","Oliver K.","O'Neil S.","Pearson D.","Quail M.A.","Rabbinowitsch E.","Rutherford K.M.","Rutter S.","Saunders D.","Seeger K.","Sharp S.","Skelton J.","Simmonds M.N.","Squares R.","Squares S.","Stevens K.","Taylor K.","Taylor R.G.","Tivey A.","Walsh S.V.","Warren T.","Whitehead S.","Woodward J.R.","Volckaert G.","Aert R.","Robben J.","Grymonprez B.","Weltjens I.","Vanstreels E.","Rieger M.","Schaefer M.","Mueller-Auer S.","Gabel C.","Fuchs M.","Duesterhoeft A.","Fritzc C.","Holzer E.","Moestl D.","Hilbert H.","Borzym K.","Langer I.","Beck A.","Lehrach H.","Reinhardt R.","Pohl T.M.","Eger P.","Zimmermann W.","Wedler H.","Wambutt R.","Purnelle B.","Goffeau A.","Cadieu E.","Dreano S.","Gloux S.","Lelaure V.","Mottier S.","Galibert F.","Aves S.J.","Xiang Z.","Hunt C.","Moore K.","Hurst S.M.","Lucas M.","Rochet M.","Gaillardin C.","Tallada V.A.","Garzon A.","Thode G.","Daga R.R.","Cruzado L.","Jimenez J.","Sanchez M.","del Rey F.","Benito J.","Dominguez A.","Revuelta J.L.","Moreno S.","Armstrong J.","Forsburg S.L.","Cerutti L.","Lowe T.","McCombie W.R.","Paulsen I.","Potashkin J.","Shpakovski G.V.","Ussery D.","Barrell B.G.","Nurse P."],"citationCrossReferences":[{"database":"PubMed","id":"11859360"},{"database":"DOI","id":"10.1038/nature724"}],"title":"The genome sequence of Schizosaccharomyces pombe.","publicationDate":"2002","journal":"Nature","firstPage":"871","lastPage":"880","volume":"415"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"972 / ATCC 24843","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"9774332","citationType":"journal article","authors":["Fernandez F.","D'Alessio C.","Fanchiotti S.","Parodi A.J."],"citationCrossReferences":[{"database":"PubMed","id":"9774332"},{"database":"DOI","id":"10.1093/emboj/17.20.5877"}],"title":"A misfolded protein conformation is not a sufficient condition for in vivo glucosylation by the UDP-Glc:glycoprotein glucosyltransferase.","publicationDate":"1998","journal":"EMBO J.","firstPage":"5877","lastPage":"5886","volume":"17"},"referencePositions":["CATALYTIC ACTIVITY","DISRUPTION PHENOTYPE"]},{"referenceNumber":3,"citation":{"id":"9813085","citationType":"journal article","authors":["Fanchiotti S.","Fernandez F.","D'Alessio C.","Parodi A.J."],"citationCrossReferences":[{"database":"PubMed","id":"9813085"},{"database":"DOI","id":"10.1083/jcb.143.3.625"}],"title":"The UDP-Glc:Glycoprotein glucosyltransferase is essential for Schizosaccharomyces pombe viability under conditions of extreme endoplasmic reticulum stress.","publicationDate":"1998","journal":"J. Cell Biol.","firstPage":"625","lastPage":"635","volume":"143"},"referencePositions":["CATALYTIC ACTIVITY","DISRUPTION PHENOTYPE"]},{"referenceNumber":4,"citation":{"id":"16823372","citationType":"journal article","authors":["Matsuyama A.","Arai R.","Yashiroda Y.","Shirai A.","Kamata A.","Sekido S.","Kobayashi Y.","Hashimoto A.","Hamamoto M.","Hiraoka Y.","Horinouchi S.","Yoshida M."],"citationCrossReferences":[{"database":"PubMed","id":"16823372"},{"database":"DOI","id":"10.1038/nbt1222"}],"title":"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.","publicationDate":"2006","journal":"Nat. Biotechnol.","firstPage":"841","lastPage":"847","volume":"24"},"referencePositions":["SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"CU329670","properties":[{"key":"ProteinId","value":"CAB65603.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"NP_593490.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001018924.3"}]},{"database":"AlphaFoldDB","id":"Q9US55","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q9US55","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"279705","properties":[{"key":"Interactions","value":"27"}]},{"database":"FunCoup","id":"Q9US55","properties":[{"key":"Number of interactors","value":"509"}]},{"database":"STRING","id":"284812.Q9US55","properties":[{"key":"Description","value":"-"}]},{"database":"CAZy","id":"GH31","properties":[{"key":"FamilyName","value":"Glycoside Hydrolase Family 31"}]},{"database":"GlyCosmos","id":"Q9US55","properties":[{"key":"glycosylation","value":"3 sites, No reported glycans"}]},{"database":"iPTMnet","id":"Q9US55","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"284812-Q9US55","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"2543277","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"spo:2543277","properties":[{"key":"Description","value":"-"}]},{"database":"PomBase","id":"SPAC1002.03c","properties":[{"key":"GeneName","value":"gls2"}]},{"database":"VEuPathDB","id":"FungiDB:SPAC1002.03c","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG1066","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_000631_7_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q9US55","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"TVHQPLW","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"PhylomeDB","id":"Q9US55","properties":[{"key":"Description","value":"-"}]},{"database":"BRENDA","id":"3.2.1.207","properties":[{"key":"OrganismId","value":"5613"}]},{"database":"UniPathway","id":"UPA00957","properties":[{"key":"RectionId","value":"-"}]},{"database":"PRO","id":"PR:Q9US55","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000002485","properties":[{"key":"Component","value":"Chromosome I"}]},{"database":"GO","id":"GO:0005783","properties":[{"key":"GoTerm","value":"C:endoplasmic reticulum"},{"key":"GoEvidenceType","value":"HDA:PomBase"}],"evidences":[{"evidenceCode":"ECO:0007005","source":"PubMed","id":"16823372"}]},{"database":"GO","id":"GO:0017177","properties":[{"key":"GoTerm","value":"C:glucosidase II complex"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0030246","properties":[{"key":"GoTerm","value":"F:carbohydrate binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0106407","properties":[{"key":"GoTerm","value":"F:Glc2Man9GlcNAc2 oligosaccharide glucosidase activity"},{"key":"GoEvidenceType","value":"IDA:PomBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"19605557"}]},{"database":"GO","id":"GO:0005975","properties":[{"key":"GoTerm","value":"P:carbohydrate metabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006491","properties":[{"key":"GoTerm","value":"P:N-glycan processing"},{"key":"GoEvidenceType","value":"IDA:PomBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"19605557"}]},{"database":"CDD","id":"cd06603","properties":[{"key":"EntryName","value":"GH31_GANC_GANAB_alpha"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd14752","properties":[{"key":"EntryName","value":"GH31_N"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.60.40.1180:FF:000023","properties":[{"key":"EntryName","value":"neutral alpha-glucosidase AB isoform X2"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.20.20.80","properties":[{"key":"EntryName","value":"Glycosidases"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.60.40.1760","properties":[{"key":"EntryName","value":"glycosyl hydrolase (family 31)"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.60.40.1180","properties":[{"key":"EntryName","value":"Golgi alpha-mannosidase II"},{"key":"MatchStatus","value":"2"}]},{"database":"InterPro","id":"IPR033403","properties":[{"key":"EntryName","value":"DUF5110"}]},{"database":"InterPro","id":"IPR011013","properties":[{"key":"EntryName","value":"Gal_mutarotase_sf_dom"}]},{"database":"InterPro","id":"IPR017853","properties":[{"key":"EntryName","value":"GH_hydrolase_sf"}]},{"database":"InterPro","id":"IPR048395","properties":[{"key":"EntryName","value":"Glyco_hydro_31_C"}]},{"database":"InterPro","id":"IPR025887","properties":[{"key":"EntryName","value":"Glyco_hydro_31_N_dom"}]},{"database":"InterPro","id":"IPR000322","properties":[{"key":"EntryName","value":"Glyco_hydro_31_TIM"}]},{"database":"InterPro","id":"IPR013780","properties":[{"key":"EntryName","value":"Glyco_hydro_b"}]},{"database":"PANTHER","id":"PTHR22762","properties":[{"key":"EntryName","value":"ALPHA-GLUCOSIDASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR22762:SF54","properties":[{"key":"EntryName","value":"BCDNA.GH04962"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF17137","properties":[{"key":"EntryName","value":"DUF5110"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13802","properties":[{"key":"EntryName","value":"Gal_mutarotas_2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01055","properties":[{"key":"EntryName","value":"Glyco_hydro_31_2nd"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF21365","properties":[{"key":"EntryName","value":"Glyco_hydro_31_3rd"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF51445","properties":[{"key":"EntryName","value":"(Trans)glycosidases"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF74650","properties":[{"key":"EntryName","value":"Galactose mutarotase-like"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF51011","properties":[{"key":"EntryName","value":"Glycosyl hydrolase domain"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MRYHGICWFIFQAAIIFAIFGSCQGAFRHQFKTAEQDGFARRNRDLAKFQKENLNWNGLFQLNSISYNSGVVSGVFEQQSENGENQHLFPFSISFLKNDVVRFQMDEKSRLEGTVEYEKNILTKRRFDASTELGFNERAEVYGKDAHLLEQTSTSLTIRYGSHGRFTVIVTFSPFKVEFQRDGEPQVVLNERHLLNMEYYRPKSSRTPEQEANGMWDETFDNFHDSKPKGPESVGLDIKFVDYGNVYGVPEHTSSLSLKETNNSDAGYTEPYRLYNVDLFEYEVDSPMSQYGAIPFMQAHKPNSDVAVFWSNAAATWIDVEKESGPSPHSQSTSTHWYSESGTLDLFIFLGPKASDVYESYSALVGRPLLPPLFSIGYHQCRWNYVSEEDVLNVDAKFDEVDMPYDTIWLDIEYASKRRYFTWDKATFPNPKAMLEKLDSKSRKLIVILDPHIKNDPNYFVSKELIDYNYAVKDKSGVDNYNADCWPGNSVWVDFFNPEAQAWWGSLYEFDRFESDKNLWIWNDMNEPSVFRGPETSMHRDAIHYGGWEHRDIHNIYGHKCINGTYNGLIKRGEGAVRPFILTRSFFAGTSALAANWIGDTMTTWEHLRGSIPTVLTNGISGMAFSGADVAGFFGNPDAELFVRWYETAIFYPFFRAHAHIDTKRREPWLYGEPYTSLVRELLRIRYRLLPTWYTAFYNSHTHGFPILYPQFLMHPEDEEGFAIDDQFYVGDSGLLVKPVTHPSIDKITIYLADDEVYFDLHDHTEYAGKGHQVVPAPLGRVPVLLRGGNILITRERIRRAAELTRNDPFTLTIAVSKIGKNASGFLYLDDGVTFNYKKGEYLIRHFSYENGILTMKDSHSNPPVSPKYSSSQKHLKVERINIYGEQTRKSIKIRKIIDSEVTEWDVSVDDSGCIRNPQLFLV","length":923,"molWeight":106282,"crc64":"C2377CCD961B4AAF","md5":"E76456C9065C0241749BFFEB7A3BB9CF"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":2,"PATHWAY":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"DISRUPTION PHENOTYPE":1,"SIMILARITY":1},"countByFeatureType":{"Signal":1,"Chain":1,"Active site":3,"Glycosylation":3},"uniParcId":"UPI000006A49D"}}