{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q9ULG3","secondaryAccessions":["Q8IXY7","Q8N5T4"],"uniProtkbId":"CFA92_HUMAN","entryAudit":{"firstPublicDate":"2008-02-26","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-02-26","entryVersion":135,"sequenceVersion":2},"annotationScore":2.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Uncharacterized protein CFAP92"}},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"HGNC","id":"HGNC:29231"}],"value":"Putative cilia and flagella associated protein 92"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"HGNC","id":"HGNC:29231"}],"value":"CFAP92"},"synonyms":[{"value":"KIAA1257"}]}],"comments":[{"commentType":"ALTERNATIVE PRODUCTS","events":["Alternative splicing"],"isoforms":[{"name":{"value":"1"},"isoformIds":["Q9ULG3-1"],"isoformSequenceStatus":"Displayed"},{"name":{"value":"2"},"isoformIds":["Q9ULG3-2"],"sequenceIds":["VSP_031739"],"isoformSequenceStatus":"Described"}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"AAH38736.1","note":"Extended N-terminus.","evidences":[{"evidenceCode":"ECO:0000305"}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"BAA86571.1","note":"Extended N-terminus.","evidences":[{"evidenceCode":"ECO:0000305"}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"EAW79289.1","note":"Extended N-terminus.","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":409,"modifier":"EXACT"}},"description":"Uncharacterized protein CFAP92","featureId":"PRO_0000320679"},{"type":"Region","location":{"start":{"value":36,"modifier":"EXACT"},"end":{"value":67,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":239,"modifier":"EXACT"},"end":{"value":298,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":338,"modifier":"EXACT"},"end":{"value":373,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":36,"modifier":"EXACT"},"end":{"value":50,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":51,"modifier":"EXACT"},"end":{"value":67,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":245,"modifier":"EXACT"},"end":{"value":265,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":268,"modifier":"EXACT"},"end":{"value":281,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":282,"modifier":"EXACT"},"end":{"value":294,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":338,"modifier":"EXACT"},"end":{"value":350,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Alternative sequence","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":112,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"15489334"}],"featureId":"VSP_031739","alternativeSequence":{}}],"keywords":[{"id":"KW-0025","category":"Coding sequence diversity","name":"Alternative splicing"},{"id":"KW-1267","category":"Technical term","name":"Proteomics identification"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"10574462","citationType":"journal article","authors":["Nagase T.","Ishikawa K.","Kikuno R.","Hirosawa M.","Nomura N.","Ohara O."],"citationCrossReferences":[{"database":"PubMed","id":"10574462"},{"database":"DOI","id":"10.1093/dnares/6.5.337"}],"title":"Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.","publicationDate":"1999","journal":"DNA Res.","firstPage":"337","lastPage":"345","volume":"6"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)"],"referenceComments":[{"value":"Brain","type":"TISSUE"}]},{"referenceNumber":2,"citation":{"id":"CI-5GBD0VIIJ7C63","citationType":"submission","authors":["Mural R.J.","Istrail S.","Sutton G.G.","Florea L.","Halpern A.L.","Mobarry C.M.","Lippert R.","Walenz B.","Shatkay H.","Dew I.","Miller J.R.","Flanigan M.J.","Edwards N.J.","Bolanos R.","Fasulo D.","Halldorsson B.V.","Hannenhalli S.","Turner R.","Yooseph S.","Lu F.","Nusskern D.R.","Shue B.C.","Zheng X.H.","Zhong F.","Delcher A.L.","Huson D.H.","Kravitz S.A.","Mouchard L.","Reinert K.","Remington K.A.","Clark A.G.","Waterman M.S.","Eichler E.E.","Adams M.D.","Hunkapiller M.W.","Myers E.W.","Venter J.C."],"publicationDate":"SEP-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":3,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)"],"referenceComments":[{"value":"Brain","type":"TISSUE"},{"value":"Testis","type":"TISSUE"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB033083","properties":[{"key":"ProteinId","value":"BAA86571.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"CH471052","properties":[{"key":"ProteinId","value":"EAW79289.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BC031632","properties":[{"key":"ProteinId","value":"AAH31632.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"BC038736","properties":[{"key":"ProteinId","value":"AAH38736.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"CCDS","id":"CCDS46905.1","properties":[{"key":"Description","value":"-"}],"isoformId":"Q9ULG3-1"},{"database":"CCDS","id":"CCDS87133.1","properties":[{"key":"Description","value":"-"}],"isoformId":"Q9ULG3-2"},{"database":"RefSeq","id":"NP_001335451.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001348522.2"}],"isoformId":"Q9ULG3-2"},{"database":"RefSeq","id":"NP_001335452.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001348523.2"}],"isoformId":"Q9ULG3-2"},{"database":"RefSeq","id":"NP_065792.1","properties":[{"key":"NucleotideSequenceId","value":"NM_020741.3"}],"isoformId":"Q9ULG3-1"},{"database":"AlphaFoldDB","id":"Q9ULG3","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"121566","properties":[{"key":"Interactions","value":"4"}]},{"database":"FunCoup","id":"Q9ULG3","properties":[{"key":"Number of interactors","value":"67"}]},{"database":"IntAct","id":"Q9ULG3","properties":[{"key":"Interactions","value":"1"}]},{"database":"STRING","id":"9606.ENSP00000265068","properties":[{"key":"Description","value":"-"}]},{"database":"GlyGen","id":"Q9ULG3","properties":[{"key":"glycosylation","value":"2 sites, 1 O-linked glycan (2 sites)"}]},{"database":"iPTMnet","id":"Q9ULG3","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q9ULG3","properties":[{"key":"Description","value":"-"}]},{"database":"SwissPalm","id":"Q9ULG3","properties":[{"key":"Description","value":"-"}]},{"database":"BioMuta","id":"KIAA1257","properties":[{"key":"Description","value":"-"}]},{"database":"DMDM","id":"172044692","properties":[{"key":"Description","value":"-"}]},{"database":"MassIVE","id":"Q9ULG3","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"9606-ENSP00000265068","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q9ULG3","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"85014","properties":[{"key":"Description","value":"-"}],"isoformId":"Q9ULG3-1"},{"database":"ProteomicsDB","id":"85015","properties":[{"key":"Description","value":"-"}],"isoformId":"Q9ULG3-2"},{"database":"Antibodypedia","id":"55543","properties":[{"key":"antibodies","value":"50 antibodies from 15 providers"}]},{"database":"DNASU","id":"57501","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENST00000265068.9","properties":[{"key":"ProteinId","value":"ENSP00000265068.5"},{"key":"GeneId","value":"ENSG00000114656.13"}],"isoformId":"Q9ULG3-1"},{"database":"Ensembl","id":"ENST00000515659.1","properties":[{"key":"ProteinId","value":"ENSP00000422539.1"},{"key":"GeneId","value":"ENSG00000114656.13"}],"isoformId":"Q9ULG3-2"},{"database":"GeneID","id":"57501","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"hsa:57501","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"uc003eli.5","properties":[{"key":"OrganismName","value":"human"}],"isoformId":"Q9ULG3-1"},{"database":"AGR","id":"HGNC:29231","properties":[{"key":"Description","value":"-"}]},{"database":"ClinPGx","id":"PA142671603","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"57501","properties":[{"key":"Description","value":"-"}]},{"database":"DisGeNET","id":"57501","properties":[{"key":"Description","value":"-"}]},{"database":"GeneCards","id":"CFAP92","properties":[{"key":"Description","value":"-"}]},{"database":"HGNC","id":"HGNC:29231","properties":[{"key":"GeneName","value":"CFAP92"}]},{"database":"HPA","id":"ENSG00000114656","properties":[{"key":"ExpressionPatterns","value":"Tissue enriched (testis)"}]},{"database":"MalaCards","id":"CFAP92","properties":[{"key":"Description","value":"-"}]},{"database":"OpenTargets","id":"ENSG00000114656","properties":[{"key":"Description","value":"-"}]},{"database":"VEuPathDB","id":"HostDB:ENSG00000114656","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG502S93N","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00390000008330","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q9ULG3","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"188352at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PAN-GO","id":"Q9ULG3","properties":[{"key":"Number of GO annotations","value":"0 GO annotations based on evolutionary models"}]},{"database":"PhylomeDB","id":"Q9ULG3","properties":[{"key":"Description","value":"-"}]},{"database":"PathwayCommons","id":"Q9ULG3","properties":[{"key":"Description","value":"-"}]},{"database":"SignaLink","id":"Q9ULG3","properties":[{"key":"Description","value":"-"}]},{"database":"Agora","id":"ENSG00000114656","properties":[{"key":"NominatedTarget","value":"-"}]},{"database":"BioGRID-ORCS","id":"57501","properties":[{"key":"hits","value":"18 hits in 1152 CRISPR screens"}]},{"database":"ChiTaRS","id":"KIAA1257","properties":[{"key":"OrganismName","value":"human"}]},{"database":"GenomeRNAi","id":"57501","properties":[{"key":"Description","value":"-"}]},{"database":"Pharos","id":"Q9ULG3","properties":[{"key":"DevelopmentLevel","value":"Tdark"}]},{"database":"PRO","id":"PR:Q9ULG3","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000005640","properties":[{"key":"Component","value":"Chromosome 3"}]},{"database":"RNAct","id":"Q9ULG3","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSG00000114656","properties":[{"key":"ExpressionPatterns","value":"Expressed in left testis and 101 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"Q9ULG3","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"InterPro","id":"IPR027876","properties":[{"key":"EntryName","value":"DUF4550"}]},{"database":"PANTHER","id":"PTHR33667:SF7","properties":[{"key":"EntryName","value":"RIKEN CDNA 1810020O05 GENE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33667","properties":[{"key":"EntryName","value":"SI:DKEY-57N24.6"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF15084","properties":[{"key":"EntryName","value":"DUF4550"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSLHAWEWEEDPASIEPISSITSFYQSTSECDVEEHLKAKARAQESDSDRPCSSIESSSEPASTFSSDVPHVVPCKFTISLAFPVNMGQKGKYASLIEKYKKHPKTDSSVTKMRRFYHIEYFLLPDDEEPKKVDILLFPMVAKVFLESGVKTVKPWHEGDKAWVSWEQTFNITVTKELLKKINFHKITLRLWNTKDKMSRKVRYYRLKTAGFTDDVGAFHKSEVRHLVLNQRKLSEQGIENTNIVREESNQEHPPGKQEKTEKHPKSLQGSHQAEPETSSKNSEEYEKSLKMDDSSTIQWSVSRTPTISLAGASMMEIKELIESESLSSLTNILDRQRSQIKGKDSEGRRKIQRRHKKPLAEEEADPTLTGPRKQSAFSIQLAVMPLLAGTHCLPCSQQLLLVLWPERP","length":409,"molWeight":46740,"crc64":"7B8A2DB2DD7F2B30","md5":"EAD586F79B3279EA547B1A4E6A063AF7"},"extraAttributes":{"countByCommentType":{"ALTERNATIVE PRODUCTS":2,"SEQUENCE CAUTION":3},"countByFeatureType":{"Chain":1,"Region":3,"Compositional bias":6,"Alternative sequence":1},"uniParcId":"UPI00001C1DE3"}}