{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q9STS6","secondaryAccessions":["B7XG83"],"uniProtkbId":"LBD27_ARATH","entryAudit":{"firstPublicDate":"2003-03-28","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2000-05-01","entryVersion":113,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Arabidopsis thaliana","commonName":"Mouse-ear cress","taxonId":3702,"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Brassicales","Brassicaceae","Camelineae","Arabidopsis"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"LOB domain-containing protein 27"}},"alternativeNames":[{"fullName":{"value":"ASYMMETRIC LEAVES 2-like protein 29"},"shortNames":[{"value":"AS2-like protein 29"}]}]},"genes":[{"geneName":{"value":"LBD27"},"synonyms":[{"value":"ASL29"}],"orderedLocusNames":[{"value":"At3g47870"}],"orfNames":[{"value":"T23J7.200"}]}],"comments":[{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"Q9STS6","intActId":"EBI-15209584"},"interactantTwo":{"uniProtKBAccession":"Q39237","geneName":"TGA1","intActId":"EBI-541351"},"numberOfExperiments":3,"organismDiffer":false}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the LOB domain-containing protein family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":328,"modifier":"EXACT"}},"description":"LOB domain-containing protein 27","featureId":"PRO_0000132278"},{"type":"Domain","location":{"start":{"value":35,"modifier":"EXACT"},"end":{"value":136,"modifier":"EXACT"}},"description":"LOB","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00291"}]}],"keywords":[{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"19154202","citationType":"journal article","authors":["Matsumura Y.","Iwakawa H.","Machida Y.","Machida C."],"citationCrossReferences":[{"database":"PubMed","id":"19154202"},{"database":"DOI","id":"10.1111/j.1365-313x.2009.03797.x"}],"title":"Characterization of genes in the ASYMMETRIC LEAVES2/LATERAL ORGAN BOUNDARIES (AS2/LOB) family in Arabidopsis thaliana, and functional and molecular comparisons between AS2 and other family members.","publicationDate":"2009","journal":"Plant J.","firstPage":"525","lastPage":"537","volume":"58"},"referencePositions":["NUCLEOTIDE SEQUENCE [MRNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"11130713","citationType":"journal article","authors":["Salanoubat M.","Lemcke K.","Rieger M.","Ansorge W.","Unseld M.","Fartmann B.","Valle G.","Bloecker H.","Perez-Alonso M.","Obermaier B.","Delseny M.","Boutry M.","Grivell L.A.","Mache R.","Puigdomenech P.","De Simone V.","Choisne N.","Artiguenave F.","Robert C.","Brottier P.","Wincker P.","Cattolico L.","Weissenbach J.","Saurin W.","Quetier F.","Schaefer M.","Mueller-Auer S.","Gabel C.","Fuchs M.","Benes V.","Wurmbach E.","Drzonek H.","Erfle H.","Jordan N.","Bangert S.","Wiedelmann R.","Kranz H.","Voss H.","Holland R.","Brandt P.","Nyakatura G.","Vezzi A.","D'Angelo M.","Pallavicini A.","Toppo S.","Simionati B.","Conrad A.","Hornischer K.","Kauer G.","Loehnert T.-H.","Nordsiek G.","Reichelt J.","Scharfe M.","Schoen O.","Bargues M.","Terol J.","Climent J.","Navarro P.","Collado C.","Perez-Perez A.","Ottenwaelder B.","Duchemin D.","Cooke R.","Laudie M.","Berger-Llauro C.","Purnelle B.","Masuy D.","de Haan M.","Maarse A.C.","Alcaraz J.-P.","Cottet A.","Casacuberta E.","Monfort A.","Argiriou A.","Flores M.","Liguori R.","Vitale D.","Mannhaupt G.","Haase D.","Schoof H.","Rudd S.","Zaccaria P.","Mewes H.-W.","Mayer K.F.X.","Kaul S.","Town C.D.","Koo H.L.","Tallon L.J.","Jenkins J.","Rooney T.","Rizzo M.","Walts A.","Utterback T.","Fujii C.Y.","Shea T.P.","Creasy T.H.","Haas B.","Maiti R.","Wu D.","Peterson J.","Van Aken S.","Pai G.","Militscher J.","Sellers P.","Gill J.E.","Feldblyum T.V.","Preuss D.","Lin X.","Nierman W.C.","Salzberg S.L.","White O.","Venter J.C.","Fraser C.M.","Kaneko T.","Nakamura Y.","Sato S.","Kato T.","Asamizu E.","Sasamoto S.","Kimura T.","Idesawa K.","Kawashima K.","Kishida Y.","Kiyokawa C.","Kohara M.","Matsumoto M.","Matsuno A.","Muraki A.","Nakayama S.","Nakazaki N.","Shinpo S.","Takeuchi C.","Wada T.","Watanabe A.","Yamada M.","Yasuda M.","Tabata S."],"citationCrossReferences":[{"database":"PubMed","id":"11130713"},{"database":"DOI","id":"10.1038/35048706"}],"title":"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.","publicationDate":"2000","journal":"Nature","firstPage":"820","lastPage":"822","volume":"408"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"27862469","citationType":"journal article","authors":["Cheng C.Y.","Krishnakumar V.","Chan A.P.","Thibaud-Nissen F.","Schobel S.","Town C.D."],"citationCrossReferences":[{"database":"PubMed","id":"27862469"},{"database":"DOI","id":"10.1111/tpj.13415"}],"title":"Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.","publicationDate":"2017","journal":"Plant J.","firstPage":"789","lastPage":"804","volume":"89"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"CI-CI4AM1G71UC0S","citationType":"submission","authoringGroup":["The Arabidopsis Information Resource (TAIR)"],"title":"Community-consensus reference genome of Arabidopsis thaliana Col-0.","publicationDate":"FEB-2026","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"12068116","citationType":"journal article","authors":["Shuai B.","Reynaga-Pena C.G.","Springer P.S."],"citationCrossReferences":[{"database":"PubMed","id":"12068116"},{"database":"DOI","id":"10.1104/pp.010926"}],"title":"The LATERAL ORGAN BOUNDARIES gene defines a novel, plant-specific gene family.","publicationDate":"2002","journal":"Plant Physiol.","firstPage":"747","lastPage":"761","volume":"129"},"referencePositions":["GENE FAMILY","NOMENCLATURE"]},{"referenceNumber":6,"citation":{"id":"12040093","citationType":"journal article","authors":["Iwakawa H.","Ueno Y.","Semiarti E.","Onouchi H.","Kojima S.","Tsukaya H.","Hasebe M.","Soma T.","Ikezaki M.","Machida C.","Machida Y."],"citationCrossReferences":[{"database":"PubMed","id":"12040093"},{"database":"DOI","id":"10.1093/pcp/pcf077"}],"title":"The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana, required for formation of a symmetric flat leaf lamina, encodes a member of a novel family of proteins characterized by cysteine repeats and a leucine zipper.","publicationDate":"2002","journal":"Plant Cell Physiol.","firstPage":"467","lastPage":"478","volume":"43"},"referencePositions":["GENE FAMILY","NOMENCLATURE"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB473862","properties":[{"key":"ProteinId","value":"BAH10573.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AL049746","properties":[{"key":"ProteinId","value":"CAB41870.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002686","properties":[{"key":"ProteinId","value":"AEE78342.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"OZ408685","properties":[{"key":"ProteinId","value":"CAO7043609.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"T07726","properties":[{"key":"EntryName","value":"T07726"}]},{"database":"RefSeq","id":"NP_190371.1","properties":[{"key":"NucleotideSequenceId","value":"NM_114657.6"}]},{"database":"AlphaFoldDB","id":"Q9STS6","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q9STS6","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"9263","properties":[{"key":"Interactions","value":"13"}]},{"database":"IntAct","id":"Q9STS6","properties":[{"key":"Interactions","value":"9"}]},{"database":"STRING","id":"3702.Q9STS6","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"3702-Q9STS6","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"823943","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ath:AT3G47870","properties":[{"key":"Description","value":"-"}]},{"database":"Araport","id":"AT3G47870","properties":[{"key":"Description","value":"-"}]},{"database":"TAIR","id":"AT3G47870","properties":[{"key":"GeneName","value":"LBD27"}]},{"database":"eggNOG","id":"ENOG502QTUX","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_073711_1_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q9STS6","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"RNGQNHP","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"PhylomeDB","id":"Q9STS6","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:Q9STS6","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000006548","properties":[{"key":"Component","value":"Chromosome 3"}]},{"database":"ExpressionAtlas","id":"Q9STS6","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IDA:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"21105930"}]},{"database":"GO","id":"GO:0001217","properties":[{"key":"GoTerm","value":"F:DNA-binding transcription repressor activity"},{"key":"GoEvidenceType","value":"IDA:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"37501369"}]},{"database":"GO","id":"GO:0009556","properties":[{"key":"GoTerm","value":"P:microsporogenesis"},{"key":"GoEvidenceType","value":"IMP:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"21105930"}]},{"database":"GO","id":"GO:0009555","properties":[{"key":"GoTerm","value":"P:pollen development"},{"key":"GoEvidenceType","value":"IMP:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"8898236"}]},{"database":"GO","id":"GO:0009786","properties":[{"key":"GoTerm","value":"P:regulation of asymmetric cell division"},{"key":"GoEvidenceType","value":"IMP:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"21105930"}]},{"database":"InterPro","id":"IPR004883","properties":[{"key":"EntryName","value":"LOB"}]},{"database":"PANTHER","id":"PTHR31301:SF21","properties":[{"key":"EntryName","value":"LOB DOMAIN-CONTAINING PROTEIN 27-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR31301","properties":[{"key":"EntryName","value":"LOB DOMAIN-CONTAINING PROTEIN 4-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03195","properties":[{"key":"EntryName","value":"LOB"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50891","properties":[{"key":"EntryName","value":"LOB"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSNTKHIHKGLQERLLDLLLIALIVYMTLKGGTSGACAACKYQRRRCAADCPLAPYFPAEQPKLFQNVHRLFGVRSIVKILEKLDETQKPEAMKSIIFQSYVRDRSPVHGCLGVTQQLQYMIWFAEEELKAVNSQLQLYRSQPQNGQNQNQNHNHNQMIHELGSDHNKQQEDVTSQQLDLGMGLNVNNNQSNVVTPFFSSLLPVSETQQPQMSYTYSCSEVNNNGYSPPAYNTDSGKEILTNNNNVWGDQNRFLYNNNNGGGYSNQNESCHEMKSNGVMAIQSQLVNLQMVSNHQRVEEEEADHEYDELHQFLDIIDDRQSFGDSKEA","length":328,"molWeight":37334,"crc64":"3DC982C9806C1D3D","md5":"628FCCB8AA56AEC6365ED1DB30DD83A3"},"extraAttributes":{"countByCommentType":{"INTERACTION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Domain":1},"uniParcId":"UPI000009FF81"}}