{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q9FN11","secondaryAccessions":["B7XG93","Q2HIV4","Q8LA66"],"uniProtkbId":"LBD37_ARATH","entryAudit":{"firstPublicDate":"2003-01-17","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2001-03-01","entryVersion":112,"sequenceVersion":1},"annotationScore":3.0,"organism":{"scientificName":"Arabidopsis thaliana","commonName":"Mouse-ear cress","taxonId":3702,"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Brassicales","Brassicaceae","Camelineae","Arabidopsis"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"value":"LOB domain-containing protein 37"}},"alternativeNames":[{"fullName":{"value":"ASYMMETRIC LEAVES 2-like protein 39"},"shortNames":[{"value":"AS2-like protein 39"}]}]},"genes":[{"geneName":{"value":"LBD37"},"synonyms":[{"value":"ASL39"}],"orderedLocusNames":[{"value":"At5g67420"}],"orfNames":[{"value":"K8K14.16"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"12068116"}],"value":"Expressed in young shoots, roots, stems, leaves and flowers"}],"commentType":"TISSUE SPECIFICITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the LOB domain-containing protein family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":250,"modifier":"EXACT"}},"description":"LOB domain-containing protein 37","featureId":"PRO_0000132287"},{"type":"Domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":107,"modifier":"EXACT"}},"description":"LOB","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00291"}]},{"type":"Region","location":{"start":{"value":145,"modifier":"EXACT"},"end":{"value":227,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":157,"modifier":"EXACT"},"end":{"value":170,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Sequence conflict","location":{"start":{"value":131,"modifier":"EXACT"},"end":{"value":131,"modifier":"EXACT"}},"description":"in Ref. 6; AAM65544","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"A","alternativeSequences":["S"]}}],"keywords":[{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"12068116","citationType":"journal article","authors":["Shuai B.","Reynaga-Pena C.G.","Springer P.S."],"citationCrossReferences":[{"database":"PubMed","id":"12068116"},{"database":"DOI","id":"10.1104/pp.010926"}],"title":"The LATERAL ORGAN BOUNDARIES gene defines a novel, plant-specific gene family.","publicationDate":"2002","journal":"Plant Physiol.","firstPage":"747","lastPage":"761","volume":"129"},"referencePositions":["NUCLEOTIDE SEQUENCE [MRNA]","TISSUE SPECIFICITY","GENE FAMILY","NOMENCLATURE"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"19154202","citationType":"journal article","authors":["Matsumura Y.","Iwakawa H.","Machida Y.","Machida C."],"citationCrossReferences":[{"database":"PubMed","id":"19154202"},{"database":"DOI","id":"10.1111/j.1365-313x.2009.03797.x"}],"title":"Characterization of genes in the ASYMMETRIC LEAVES2/LATERAL ORGAN BOUNDARIES (AS2/LOB) family in Arabidopsis thaliana, and functional and molecular comparisons between AS2 and other family members.","publicationDate":"2009","journal":"Plant J.","firstPage":"525","lastPage":"537","volume":"58"},"referencePositions":["NUCLEOTIDE SEQUENCE [MRNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"9501997","citationType":"journal article","authors":["Nakamura Y.","Sato S.","Kaneko T.","Kotani H.","Asamizu E.","Miyajima N.","Tabata S."],"citationCrossReferences":[{"database":"PubMed","id":"9501997"},{"database":"DOI","id":"10.1093/dnares/4.6.401"}],"title":"Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence features of the regions of 1,191,918 bp covered by seventeen physically assigned P1 clones.","publicationDate":"1997","journal":"DNA Res.","firstPage":"401","lastPage":"414","volume":"4"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"27862469","citationType":"journal article","authors":["Cheng C.Y.","Krishnakumar V.","Chan A.P.","Thibaud-Nissen F.","Schobel S.","Town C.D."],"citationCrossReferences":[{"database":"PubMed","id":"27862469"},{"database":"DOI","id":"10.1111/tpj.13415"}],"title":"Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.","publicationDate":"2017","journal":"Plant J.","firstPage":"789","lastPage":"804","volume":"89"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"CI-CI4AM1G71UC0S","citationType":"submission","authoringGroup":["The Arabidopsis Information Resource (TAIR)"],"title":"Community-consensus reference genome of Arabidopsis thaliana Col-0.","publicationDate":"FEB-2026","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":6,"citation":{"id":"CI-3TH3AFLAVIRO9","citationType":"submission","authors":["Brover V.V.","Troukhan M.E.","Alexandrov N.A.","Lu Y.-P.","Flavell R.B.","Feldmann K.A."],"title":"Full-length cDNA from Arabidopsis thaliana.","publicationDate":"MAR-2002","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"]},{"referenceNumber":7,"citation":{"id":"CI-E4RGTNQ8QTESC","citationType":"submission","authors":["Shinn P.","Chen H.","Kim C.J.","Ecker J.R."],"title":"Arabidopsis ORF clones.","publicationDate":"FEB-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":8,"citation":{"id":"12040093","citationType":"journal article","authors":["Iwakawa H.","Ueno Y.","Semiarti E.","Onouchi H.","Kojima S.","Tsukaya H.","Hasebe M.","Soma T.","Ikezaki M.","Machida C.","Machida Y."],"citationCrossReferences":[{"database":"PubMed","id":"12040093"},{"database":"DOI","id":"10.1093/pcp/pcf077"}],"title":"The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana, required for formation of a symmetric flat leaf lamina, encodes a member of a novel family of proteins characterized by cysteine repeats and a leucine zipper.","publicationDate":"2002","journal":"Plant Cell Physiol.","firstPage":"467","lastPage":"478","volume":"43"},"referencePositions":["GENE FAMILY","NOMENCLATURE"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AF447894","properties":[{"key":"ProteinId","value":"AAL38039.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AB473872","properties":[{"key":"ProteinId","value":"BAH10583.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AB007645","properties":[{"key":"ProteinId","value":"BAB09027.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002688","properties":[{"key":"ProteinId","value":"AED98342.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002688","properties":[{"key":"ProteinId","value":"ANM69094.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"OZ408687","properties":[{"key":"ProteinId","value":"CAO7058158.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY087998","properties":[{"key":"ProteinId","value":"AAM65544.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"BT024477","properties":[{"key":"ProteinId","value":"ABD19658.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"RefSeq","id":"NP_001318897.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001345828.1"}]},{"database":"RefSeq","id":"NP_201543.1","properties":[{"key":"NucleotideSequenceId","value":"NM_126142.5"}]},{"database":"AlphaFoldDB","id":"Q9FN11","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q9FN11","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"22120","properties":[{"key":"Interactions","value":"6"}]},{"database":"FunCoup","id":"Q9FN11","properties":[{"key":"Number of interactors","value":"194"}]},{"database":"STRING","id":"3702.Q9FN11","properties":[{"key":"Description","value":"-"}]},{"database":"GlyGen","id":"Q9FN11","properties":[{"key":"glycosylation","value":"1 site"}]},{"database":"PaxDb","id":"3702-Q9FN11","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"237080","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"836878","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ath:AT5G67420","properties":[{"key":"Description","value":"-"}]},{"database":"Araport","id":"AT5G67420","properties":[{"key":"Description","value":"-"}]},{"database":"TAIR","id":"AT5G67420","properties":[{"key":"GeneName","value":"LBD37"}]},{"database":"eggNOG","id":"ENOG502QU8T","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_054665_1_1_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q9FN11","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"WDNTATG","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"1922547at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"Q9FN11","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:Q9FN11","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000006548","properties":[{"key":"Component","value":"Chromosome 5"}]},{"database":"ExpressionAtlas","id":"Q9FN11","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0005739","properties":[{"key":"GoTerm","value":"C:mitochondrion"},{"key":"GoEvidenceType","value":"ISM:TAIR"}]},{"database":"GO","id":"GO:0001217","properties":[{"key":"GoTerm","value":"F:DNA-binding transcription repressor activity"},{"key":"GoEvidenceType","value":"IDA:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"37501369"}]},{"database":"GO","id":"GO:0000976","properties":[{"key":"GoTerm","value":"F:transcription cis-regulatory region binding"},{"key":"GoEvidenceType","value":"IPI:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000353","source":"PubMed","id":"30356219"}]},{"database":"GO","id":"GO:0060776","properties":[{"key":"GoTerm","value":"P:simple leaf morphogenesis"},{"key":"GoEvidenceType","value":"IMP:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"20085895"}]},{"database":"InterPro","id":"IPR004883","properties":[{"key":"EntryName","value":"LOB"}]},{"database":"PANTHER","id":"PTHR31304:SF35","properties":[{"key":"EntryName","value":"LOB DOMAIN-CONTAINING PROTEIN 37"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR31304","properties":[{"key":"EntryName","value":"LOB DOMAIN-CONTAINING PROTEIN 38"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF03195","properties":[{"key":"EntryName","value":"LOB"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50891","properties":[{"key":"EntryName","value":"LOB"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSCNGCRVLRKGCSENCILRPCIQWIETADAQGHATVFVAKFFGRAGLMSFISAVPDSQRPALFQSLLYEACGRTVNPVNGAIGMLWTGNWNICQAAVETVLRGGSLRPIPELLTHGGGFAGFPSPTSEEASEICTEMLNLQQNDSTDRNIYHHSRFSSSRSRSTMDSSSPTKRKRLSSEDQPSSELDLSLIPNFPIKQATPSSTRRRSVTPSMNSEDSGTTTTTTAFCDKGDVYGNGGGETTKLLNLFV","length":250,"molWeight":27113,"crc64":"C1276BF727008A27","md5":"3C124F5C4FB1BA2D381E5274EC33DDAB"},"extraAttributes":{"countByCommentType":{"TISSUE SPECIFICITY":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Domain":1,"Region":1,"Compositional bias":1,"Sequence conflict":1},"uniParcId":"UPI000012E248"}}