{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q9D711","secondaryAccessions":["A2AIH9","Q3UAN0","Q8CIE9"],"uniProtkbId":"PIR_MOUSE","entryAudit":{"firstPublicDate":"2001-06-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2001-06-01","entryVersion":160,"sequenceVersion":1},"annotationScore":4.0,"organism":{"scientificName":"Mus musculus","commonName":"Mouse","taxonId":10090,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Glires","Rodentia","Myomorpha","Muroidea","Muridae","Murinae","Mus","Mus"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Pirin"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"O00625"}],"value":"1.13.11.24"}]},"alternativeNames":[{"fullName":{"value":"Probable quercetin 2,3-dioxygenase PIR"},"shortNames":[{"value":"Probable quercetinase"}]}]},"genes":[{"geneName":{"value":"Pir"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"O00625"}],"value":"Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro)"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"quercetin + O2 = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:15381"},{"database":"ChEBI","id":"CHEBI:15379"},{"database":"ChEBI","id":"CHEBI:17245"},{"database":"ChEBI","id":"CHEBI:57628"},{"database":"ChEBI","id":"CHEBI:57694"}],"ecNumber":"1.13.11.24","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"O00625"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"Fe cation","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"O00625"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:24875"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"O00625"}],"value":"Binds 1 Fe cation per subunit."}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"O00625"}],"value":"Flavonoid metabolism; quercetin degradation"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"O00625"}],"value":"May interact with NF1/CTF1. Interacts with BCL3. Identified in a complex comprised of PIR, BLC3, NFKB1 and target DNA"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"O00625"}],"value":"Predominantly localized in dot-like subnuclear structures"}]},"subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"O00625"}],"value":"Nucleus","id":"SL-0191"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"O00625"}],"value":"Cytoplasm","id":"SL-0086"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"20010624"}],"value":"Weakly expressed in bone marrow"}],"commentType":"TISSUE SPECIFICITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"20010624"}],"value":"Down-regulated in mice with acute myeloid leukemias induced by either PML-RAR or AML1-ETO fusion oncoproteins"}],"commentType":"INDUCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Quercetin is a flavonoid compound synthesized by a variety of plants, including foods for human consumption"}],"commentType":"MISCELLANEOUS"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the pirin family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":290,"modifier":"EXACT"}},"description":"Pirin","featureId":"PRO_0000214052"},{"type":"Binding site","location":{"start":{"value":56,"modifier":"EXACT"},"end":{"value":56,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000250"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875"}},{"type":"Binding site","location":{"start":{"value":58,"modifier":"EXACT"},"end":{"value":58,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000250"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875"}},{"type":"Binding site","location":{"start":{"value":101,"modifier":"EXACT"},"end":{"value":101,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000250"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875"}},{"type":"Binding site","location":{"start":{"value":103,"modifier":"EXACT"},"end":{"value":103,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:24875"}],"evidences":[{"evidenceCode":"ECO:0000250"}],"ligand":{"name":"Fe cation","id":"ChEBI:CHEBI:24875"}},{"type":"Sequence conflict","location":{"start":{"value":49,"modifier":"EXACT"},"end":{"value":49,"modifier":"EXACT"}},"description":"in Ref. 2; AAH24062","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"K","alternativeSequences":["R"]}}],"keywords":[{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0223","category":"Molecular function","name":"Dioxygenase"},{"id":"KW-0408","category":"Ligand","name":"Iron"},{"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0804","category":"Biological process","name":"Transcription"},{"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"16141072","citationType":"journal article","authors":["Carninci P.","Kasukawa T.","Katayama S.","Gough J.","Frith M.C.","Maeda N.","Oyama R.","Ravasi T.","Lenhard B.","Wells C.","Kodzius R.","Shimokawa K.","Bajic V.B.","Brenner S.E.","Batalov S.","Forrest A.R.","Zavolan M.","Davis M.J.","Wilming L.G.","Aidinis V.","Allen J.E.","Ambesi-Impiombato A.","Apweiler R.","Aturaliya R.N.","Bailey T.L.","Bansal M.","Baxter L.","Beisel K.W.","Bersano T.","Bono H.","Chalk A.M.","Chiu K.P.","Choudhary V.","Christoffels A.","Clutterbuck D.R.","Crowe M.L.","Dalla E.","Dalrymple B.P.","de Bono B.","Della Gatta G.","di Bernardo D.","Down T.","Engstrom P.","Fagiolini M.","Faulkner G.","Fletcher C.F.","Fukushima T.","Furuno M.","Futaki S.","Gariboldi M.","Georgii-Hemming P.","Gingeras T.R.","Gojobori T.","Green R.E.","Gustincich S.","Harbers M.","Hayashi Y.","Hensch T.K.","Hirokawa N.","Hill D.","Huminiecki L.","Iacono M.","Ikeo K.","Iwama A.","Ishikawa T.","Jakt M.","Kanapin A.","Katoh M.","Kawasawa Y.","Kelso J.","Kitamura H.","Kitano H.","Kollias G.","Krishnan S.P.","Kruger A.","Kummerfeld S.K.","Kurochkin I.V.","Lareau L.F.","Lazarevic D.","Lipovich L.","Liu J.","Liuni S.","McWilliam S.","Madan Babu M.","Madera M.","Marchionni L.","Matsuda H.","Matsuzawa S.","Miki H.","Mignone F.","Miyake S.","Morris K.","Mottagui-Tabar S.","Mulder N.","Nakano N.","Nakauchi H.","Ng P.","Nilsson R.","Nishiguchi S.","Nishikawa S.","Nori F.","Ohara O.","Okazaki Y.","Orlando V.","Pang K.C.","Pavan W.J.","Pavesi G.","Pesole G.","Petrovsky N.","Piazza S.","Reed J.","Reid J.F.","Ring B.Z.","Ringwald M.","Rost B.","Ruan Y.","Salzberg S.L.","Sandelin A.","Schneider C.","Schoenbach C.","Sekiguchi K.","Semple C.A.","Seno S.","Sessa L.","Sheng Y.","Shibata Y.","Shimada H.","Shimada K.","Silva D.","Sinclair B.","Sperling S.","Stupka E.","Sugiura K.","Sultana R.","Takenaka Y.","Taki K.","Tammoja K.","Tan S.L.","Tang S.","Taylor M.S.","Tegner J.","Teichmann S.A.","Ueda H.R.","van Nimwegen E.","Verardo R.","Wei C.L.","Yagi K.","Yamanishi H.","Zabarovsky E.","Zhu S.","Zimmer A.","Hide W.","Bult C.","Grimmond S.M.","Teasdale R.D.","Liu E.T.","Brusic V.","Quackenbush J.","Wahlestedt C.","Mattick J.S.","Hume D.A.","Kai C.","Sasaki D.","Tomaru Y.","Fukuda S.","Kanamori-Katayama M.","Suzuki M.","Aoki J.","Arakawa T.","Iida J.","Imamura K.","Itoh M.","Kato T.","Kawaji H.","Kawagashira N.","Kawashima T.","Kojima M.","Kondo S.","Konno H.","Nakano K.","Ninomiya N.","Nishio T.","Okada M.","Plessy C.","Shibata K.","Shiraki T.","Suzuki S.","Tagami M.","Waki K.","Watahiki A.","Okamura-Oho Y.","Suzuki H.","Kawai J.","Hayashizaki Y."],"citationCrossReferences":[{"database":"PubMed","id":"16141072"},{"database":"DOI","id":"10.1126/science.1112014"}],"title":"The transcriptional landscape of the mammalian genome.","publicationDate":"2005","journal":"Science","firstPage":"1559","lastPage":"1563","volume":"309"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"C57BL/6J","type":"STRAIN"},{"value":"Bone marrow","type":"TISSUE"},{"value":"Hypothalamus","type":"TISSUE"},{"value":"Tongue","type":"TISSUE"}]},{"referenceNumber":2,"citation":{"id":"19468303","citationType":"journal article","authors":["Church D.M.","Goodstadt L.","Hillier L.W.","Zody M.C.","Goldstein S.","She X.","Bult C.J.","Agarwala R.","Cherry J.L.","DiCuccio M.","Hlavina W.","Kapustin Y.","Meric P.","Maglott D.","Birtle Z.","Marques A.C.","Graves T.","Zhou S.","Teague B.","Potamousis K.","Churas C.","Place M.","Herschleb J.","Runnheim R.","Forrest D.","Amos-Landgraf J.","Schwartz D.C.","Cheng Z.","Lindblad-Toh K.","Eichler E.E.","Ponting C.P."],"citationCrossReferences":[{"database":"PubMed","id":"19468303"},{"database":"DOI","id":"10.1371/journal.pbio.1000112"}],"title":"Lineage-specific biology revealed by a finished genome assembly of the mouse.","publicationDate":"2009","journal":"PLoS Biol.","firstPage":"E1000112","lastPage":"E1000112","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"C57BL/6J","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"CI-70VOB8UOSDVQL","citationType":"submission","authors":["Mural R.J.","Adams M.D.","Myers E.W.","Smith H.O.","Venter J.C."],"publicationDate":"SEP-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":4,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Czech II","type":"STRAIN"},{"value":"Mammary tumor","type":"TISSUE"}]},{"referenceNumber":5,"citation":{"id":"CI-5RQ3JLJL70LE7","citationType":"submission","authors":["Teng X.","Li D.","Johns R.A."],"title":"Hypoxia upregulates VEGF-D promoter in pulmonary vascular smooth muscle cells.","publicationDate":"FEB-2001","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 255-290"],"referenceComments":[{"value":"ICR","type":"STRAIN"}]},{"referenceNumber":6,"citation":{"id":"21183079","citationType":"journal article","authors":["Huttlin E.L.","Jedrychowski M.P.","Elias J.E.","Goswami T.","Rad R.","Beausoleil S.A.","Villen J.","Haas W.","Sowa M.E.","Gygi S.P."],"citationCrossReferences":[{"database":"PubMed","id":"21183079"},{"database":"DOI","id":"10.1016/j.cell.2010.12.001"}],"title":"A tissue-specific atlas of mouse protein phosphorylation and expression.","publicationDate":"2010","journal":"Cell","firstPage":"1174","lastPage":"1189","volume":"143"},"referencePositions":["IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"],"referenceComments":[{"value":"Liver","type":"TISSUE"},{"value":"Lung","type":"TISSUE"},{"value":"Spleen","type":"TISSUE"}]},{"referenceNumber":7,"citation":{"id":"20010624","citationType":"journal article","authors":["Licciulli S.","Cambiaghi V.","Scafetta G.","Gruszka A.M.","Alcalay M."],"citationCrossReferences":[{"database":"PubMed","id":"20010624"},{"database":"DOI","id":"10.1038/leu.2009.247"}],"title":"Pirin downregulation is a feature of AML and leads to impairment of terminal myeloid differentiation.","publicationDate":"2010","journal":"Leukemia","firstPage":"429","lastPage":"437","volume":"24"},"referencePositions":["FUNCTION","TISSUE SPECIFICITY","INDUCTION"],"referenceComments":[{"value":"129/SvEv","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AK009757","properties":[{"key":"ProteinId","value":"BAB26481.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK138314","properties":[{"key":"ProteinId","value":"BAE23621.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK151301","properties":[{"key":"ProteinId","value":"BAE30284.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AL671706","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AL732475","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CH466571","properties":[{"key":"ProteinId","value":"EDL40759.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BC024062","properties":[{"key":"ProteinId","value":"AAH24062.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AF345635","properties":[{"key":"ProteinId","value":"AAK54068.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"CCDS","id":"CCDS30520.1","properties":[{"key":"Description","value":"-"}]},{"database":"RefSeq","id":"NP_081429.1","properties":[{"key":"NucleotideSequenceId","value":"NM_027153.3"}]},{"database":"RefSeq","id":"XP_036017982.1","properties":[{"key":"NucleotideSequenceId","value":"XM_036162089.1"}]},{"database":"AlphaFoldDB","id":"Q9D711","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q9D711","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"213592","properties":[{"key":"Interactions","value":"2"}]},{"database":"FunCoup","id":"Q9D711","properties":[{"key":"Number of interactors","value":"1296"}]},{"database":"STRING","id":"10090.ENSMUSP00000033749","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"Q9D711","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q9D711","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"Q9D711","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"10090-ENSMUSP00000033749","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"289579","properties":[{"key":"Description","value":"-"}]},{"database":"Pumba","id":"Q9D711","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"358","properties":[{"key":"antibodies","value":"218 antibodies from 31 providers"}]},{"database":"DNASU","id":"69656","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENSMUST00000033749.9","properties":[{"key":"ProteinId","value":"ENSMUSP00000033749.8"},{"key":"GeneId","value":"ENSMUSG00000031379.14"}]},{"database":"GeneID","id":"69656","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"mmu:69656","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"uc009uvl.2","properties":[{"key":"OrganismName","value":"mouse"}]},{"database":"AGR","id":"MGI:1916906","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"8544","properties":[{"key":"Description","value":"-"}]},{"database":"MGI","id":"MGI:1916906","properties":[{"key":"GeneName","value":"Pir"}]},{"database":"VEuPathDB","id":"HostDB:ENSMUSG00000031379","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG502QQ5A","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00390000008044","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_045717_0_1_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q9D711","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"TPWHPHR","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"198735at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"Q9D711","properties":[{"key":"Description","value":"-"}]},{"database":"Reactome","id":"R-MMU-8935690","properties":[{"key":"PathwayName","value":"Digestion"}]},{"database":"UniPathway","id":"UPA00724","properties":[{"key":"RectionId","value":"-"}]},{"database":"BioGRID-ORCS","id":"69656","properties":[{"key":"hits","value":"3 hits in 76 CRISPR screens"}]},{"database":"PRO","id":"PR:Q9D711","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000589","properties":[{"key":"Component","value":"Chromosome X"}]},{"database":"RNAct","id":"Q9D711","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSMUSG00000031379","properties":[{"key":"ExpressionPatterns","value":"Expressed in esophagus and 192 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"Q9D711","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"ISO:GO_Central"}]},{"database":"GO","id":"GO:0016604","properties":[{"key":"GoTerm","value":"C:nuclear body"},{"key":"GoEvidenceType","value":"ISO:GO_Central"}]},{"database":"GO","id":"GO:0005654","properties":[{"key":"GoTerm","value":"C:nucleoplasm"},{"key":"GoEvidenceType","value":"ISO:GO_Central"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0046872","properties":[{"key":"GoTerm","value":"F:metal ion binding"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0008127","properties":[{"key":"GoTerm","value":"F:quercetin 2,3-dioxygenase activity"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0003712","properties":[{"key":"GoTerm","value":"F:transcription coregulator activity"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0030224","properties":[{"key":"GoTerm","value":"P:monocyte differentiation"},{"key":"GoEvidenceType","value":"ISO:MGI"}],"evidences":[{"evidenceCode":"ECO:0000266","source":"PubMed","id":"20010624"}]},{"database":"GO","id":"GO:0030099","properties":[{"key":"GoTerm","value":"P:myeloid cell differentiation"},{"key":"GoEvidenceType","value":"IMP:MGI"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"20010624"}]},{"database":"CDD","id":"cd20288","properties":[{"key":"EntryName","value":"cupin_pirin-like_C"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd02909","properties":[{"key":"EntryName","value":"cupin_pirin_N"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.60.120.10:FF:000055","properties":[{"key":"EntryName","value":"pirin"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.60.120.10","properties":[{"key":"EntryName","value":"Jelly Rolls"},{"key":"MatchStatus","value":"2"}]},{"database":"InterPro","id":"IPR012093","properties":[{"key":"EntryName","value":"Pirin"}]},{"database":"InterPro","id":"IPR008778","properties":[{"key":"EntryName","value":"Pirin_C_dom"}]},{"database":"InterPro","id":"IPR003829","properties":[{"key":"EntryName","value":"Pirin_N_dom"}]},{"database":"InterPro","id":"IPR014710","properties":[{"key":"EntryName","value":"RmlC-like_jellyroll"}]},{"database":"InterPro","id":"IPR011051","properties":[{"key":"EntryName","value":"RmlC_Cupin_sf"}]},{"database":"PANTHER","id":"PTHR13903:SF8","properties":[{"key":"EntryName","value":"PIRIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR13903","properties":[{"key":"EntryName","value":"PIRIN-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02678","properties":[{"key":"EntryName","value":"Pirin"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF05726","properties":[{"key":"EntryName","value":"Pirin_C"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF006232","properties":[{"key":"EntryName","value":"Pirin"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF51182","properties":[{"key":"EntryName","value":"RmlC-like cupins"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MASSKKVTLSVLSREQSEGVGARVRRSIGRPELKNLDPFLLFDEFKGGKPGGFPDHPHRGFETVSYLLEGGSMAHEDFCGHVGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNLRRSEKMVAPQYQELKSEEIPKPTKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDQGAKHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHHTAVLGEGDAVQLENKDPKRSHFVLIAGEPLREPVVQHGPFVMNTNEEISQAILDFRNAKNGFEGARTWKSKIGN","length":290,"molWeight":32066,"crc64":"B95915522F62EC5F","md5":"E9A8F4D68AF0DB36A6B9A55CFE6366B8"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"COFACTOR":1,"PATHWAY":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"TISSUE SPECIFICITY":1,"INDUCTION":1,"MISCELLANEOUS":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Binding site":4,"Sequence conflict":1},"uniParcId":"UPI0000023772"}}