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This observation has been challenged by experiments showing KGD4 copurification with the oxoglutarate dehydrogenase complex (OGDHC), also called alpha-ketoglutarate dehydrogenase complex (KGDH). Both mitochondrial ribosome 28S subunit and OGDC have a similar size and OGDC is highly abundant, therefore OGDC has been found to contaminate ribosomal preparations performed by sequential centrifugation steps (PubMed:25165143). 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